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    SYNTHESIS AND USE OF GRAFTED GRAPHENE IN OIL BASED DRILLING FLUIDS AS A LOW SHEAR RATE VISCOSITY ENHANCER
    1.
    发明公开
    SYNTHESIS AND USE OF GRAFTED GRAPHENE IN OIL BASED DRILLING FLUIDS AS A LOW SHEAR RATE VISCOSITY ENHANCER 审中-公开

    公开(公告)号：US20240343966A1

    公开(公告)日：2024-10-17

    申请号：US18756356

    申请日：2024-06-27

    申请人： SAUDI ARABIAN OIL COMPANY

    发明人： Ashok Santra ,  Carl J. Thaemlitz

    IPC分类号： C09K8/34 ,  C08F292/00

    CPC分类号： C09K8/34 ,  C08F292/00 ,  C09K2208/34

    摘要： A composition that includes a polymer-grafted graphene particle and oil-based drilling fluid is provided. At least one side of the graphene particle comprises a grafted polymer. A method of using an oil-based drilling fluid is also provided. The method includes introducing the oil-based drilling fluid into a wellbore and circulating the oil-based drilling fluid during drilling operations. The drilling fluid includes a polymer-grafted graphene particle and oil-based drilling fluid. At least one side of the graphene particle comprises a grafted polymer. The oil-based drilling fluid includes a range of from about 0.01 ppb to 10 ppb of the polymer-grafted graphene particle.

    GENERIC HIGH-CAPACITY PROTEIN CAPTURE AND TUNABLE ELECTROCHEMICAL RELEASE
    9.
    发明申请
    GENERIC HIGH-CAPACITY PROTEIN CAPTURE AND TUNABLE ELECTROCHEMICAL RELEASE 有权

    公开(公告)号：US20220409726A1

    公开(公告)日：2022-12-29

    申请号：US17756253

    申请日：2020-11-19

    申请人： Nyctea Technologies AB

    发明人： Gustav Ferrand-Drake del Castillo ,  Andreas Dahlin

    IPC分类号： A61K41/00 ,  C08F292/00 ,  A61K47/64 ,  A61K47/60 ,  A61K47/69 ,  A61K47/58

    摘要： An electrochemical catch-release system (1) for repeated use comprising pH-responsive polymers (2) covalently linked to a structure (3) via a monolayer (4) of eletrochemically insensitive aryl bonds, forming a polyelectrolyte arrangement (5), the polyelectrolyte arrangement (5) being arranged to, when the covalently bounded polymers (2) are in a neutral state, catch an entity (6) being a protein, a vesicle, or a compound modified with poly(ethylene glycol) by non-electrostatic interactions e.g. hydrogen bonds, and when the polymers (2) are in a charged state, release by electrostatic repulsion an entity (6) captured by the polyelectrolyte arrangement (5). The system also comprising a device (7) for applying an electrochemical potential to the polyelectrolyte arrangement (5) to induce a switch of the polyelectrolyte arrangement (5) from the neutral state to the charged state or the reverse in the presence of redox active species.

    BIOMAGNETIC MICROSPHERE AND PREPARATION METHOD AND USE METHOD THEREFOR
    10.
    发明申请
    BIOMAGNETIC MICROSPHERE AND PREPARATION METHOD AND USE METHOD THEREFOR 有权

    公开(公告)号：US20220372196A1

    公开(公告)日：2022-11-24

    申请号：US17621432

    申请日：2020-06-19

    申请人： KANGMA-HEALTHCODE (SHANGHAI) BIOTECH CO., LTD.

    发明人： Min GUO ,  Liang WU ,  Liqiong XU ,  Zheng ZHANG ,  Jie SU ,  Xue YU

    IPC分类号： C08F292/00 ,  C07K1/22

    摘要： A biomagnetic microsphere and a preparation method and a method for protein isolation and purification therefor. The outer surface of a magnetic microsphere body of the biomagnetic microsphere has at least one liner polymer with a branched chain; one end of the linear polymer with a branched chain is covalently coupled to the outer surface of the magnetic microsphere body, and other parts are free on the outer surface of the magnetic microsphere body; a backbone of the linear polymer is a polyolefin backbone, and no cross-linking agent is required in the backbone forming process of the linear polymer. The prepared biomagnetic microsphere can implement efficient elution of target proteins and effectively reduce the retention time and retention ratio of the target proteins, and it is easy to operate and widely used.