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    METHODS AND KITS OF DETERMINING WHETHER A SUBJECT IS SUSCEPTIBLE TO HAVE A HYPER-AGGRESSIVE BEHAVIOUR
    2.
    发明申请
    METHODS AND KITS OF DETERMINING WHETHER A SUBJECT IS SUSCEPTIBLE TO HAVE A HYPER-AGGRESSIVE BEHAVIOUR 审中-公开
    方法和方法确定一个主体是否可以拥有一个更高的行为

    公开(公告)号：US20160123989A1

    公开(公告)日：2016-05-05

    申请号：US14898628

    申请日：2014-06-20

    申请人： INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) ,  UNIVERSITÉ DE ROUEN ,  CENTRE HOSPITALIER UNIVERSITAIRE DE ROUEN ,  AKERSHUS UNIVERSITETSSYKEHUS HF

    发明人： Serguei FETISSOV ,  Pierre DECHELOTTE ,  Henning VÆRØY ,  Romain LEGRAND

    IPC分类号： G01N33/68

    CPC分类号： G01N33/6854 ,  G01N33/74 ,  G01N2333/695

    摘要： The present invention relates to methods and kits of determining whether a subject is susceptible to have a hyper-aggressive behaviour. In particular, the present invention relates to a method for determining whether a subject is susceptible to have a hyper-aggressive behaviour comprising the steps consisting of i) isolating the auto antibodies that bind to adrenocorticotropic hormone (ACTH) from a blood sample obtained from the subject, ii) determining the affinity of the isolated autoantibodies iii) comparing the affinity determined at step ii) with a predetermined reference value and iv) concluding that the subject is susceptible to have a hyper-aggressive behaviour when the affinity determined at step ii) is higher than the predetermined reference value.

    摘要翻译： 本发明涉及确定受试者是否容易具有过度侵袭行为的方法和试剂盒。 特别地，本发明涉及一种用于确定受试者是否易于具有过度侵袭行为的方法，该方法包括以下步骤：i）从获得的血液样品中分离与促肾上腺皮质激素（ACTH）结合的自身抗体 主题，ii）确定分离的自身抗体的亲和力iii）将在步骤ii）中确定的亲和力与预定参考值进行比较，以及iv）当在步骤ii）确定的亲和力确定受试者易于具有过度侵袭行为时， 高于预定的参考值。