公开(公告)号：US20190049708A1

公开(公告)日：2019-02-14

申请号：US16041922

申请日：2018-07-23

Applicant: TECAN TRADING AG

Inventor： Andreas ERLBACHER ,  Markus SCHÜRF ,  Josef GRASSL ,  Alexander KASER

IPC: G02B21/00 ,  G02B21/24 ,  G02B21/06 ,  G02B21/36

Abstract: A system 100 and method are provided for imaging a sample in a sample holder. For providing autofocus, a 2D pattern is projected onto the sample holder 050 via an astigmatic optical element 120. Image data 172 of the sample is acquired by an image sensor 140 via magnification optics 150. A difference in sharpness of the two-dimensional pattern in the image data is measured along a first axis and a second axis. Based on the difference, a magnitude and direction of defocus of the camera subsystem is determined with respect to the sample holder. This enables the sample holder, and thereby the sample, to be brought into focus in a fast and reliable manner.

公开(公告)号：US20160018429A1

公开(公告)日：2016-01-21

申请号：US14870673

申请日：2015-09-30

Applicant: TECAN Trading AG

Inventor： Florian REINER ,  Harald GEBETHSROITHER ,  Josef GRASSL

IPC: G01N35/02 ,  G01N21/25 ,  G01N21/64

CPC classification number: G01N35/028 ,  B01L9/52 ,  C12M1/04 ,  C12M41/14 ,  C12M41/16 ,  C12Q1/02 ,  G01J3/12 ,  G01N21/253 ,  G01N21/6452 ,  G01N33/5005 ,  G01N2035/00356 ,  G01N2201/023 ,  G01N2201/0231 ,  G01N2201/0238 ,  G01N2201/0446 ,  G01N2201/06113

Abstract: The invention relates to a microplate reader and a respective method, wherein the microplate reader comprises at least one measuring device and a holding device for accommodating at least one microplate and for positioning the samples-containing wells of this(these) microplate(s) in relation to the at least one measuring device. The at least one measuring device is used for detecting light which is emitted by samples in wells of a microplate inserted in this microplate reader and/or which is influenced by samples transilluminated by light in wells of a microplate inserted in this microplate reader. The microplate reader comprises a control unit for controlling the temperature of a gas atmosphere surrounding the wells containing the samples of microplates used in this microplate reader.

Abstract translation: 本发明涉及一种酶标仪和相应的方法，其中该酶标仪包括至少一个测量装置和用于容纳至少一个微孔板的保持装置，并将该（微）微孔板的含样品的孔定位在 与至少一个测量装置的关系。 所述至少一个测量装置用于检测由插入该酶标板读数器中的微孔板的孔中的样品发出的光，和/或由插入该酶标板读数器中的微板的孔中的光透过的样品影响。 酶标仪包括用于控制包含在该酶标板读数器中使用的微孔板样品的孔周围的气体气氛的温度的控制单元。

公开(公告)号：US20240210124A1

公开(公告)日：2024-06-27

申请号：US18390579

申请日：2023-12-20

Applicant: TECAN TRADING AG

Inventor： Waltraud LAMPRECHT ,  Manfred LANSING ,  Josef GRASSL ,  Tobias SAWETZKI

IPC: F28F3/12 ,  B01L3/00 ,  F28F21/06 ,  F28F21/08

CPC classification number: F28F3/12 ,  B01L3/5027 ,  F28F21/062 ,  F28F21/081 ,  B01L2300/18

Abstract: A temperature equalizing plate (1) for a micro plate reader (4), onto which temperature equalizing plate (1) a microplate with wells can be removably arranged, the temperature equalizing plate (1) having a plate-shaped body, wherein a first vertical offset is provided between four upward facing corner surfaces (100) and four upward facing edge surfaces (110) and wherein a second vertical offset is provided between the four upward facing edge surfaces (110) and one upward facing center surface (120), resulting in gaps between at least some of the upward facing surfaces (100;110;120) of the temperature equalizing plate (1) and corresponding wells of the thereon arranged microplate.

公开(公告)号：US20210181223A1

公开(公告)日：2021-06-17

申请号：US17120882

申请日：2020-12-14

Applicant: TECAN TRADING AG

Inventor： Gerald ZERZA ,  Josef GRASSL ,  Alwin SCHULLER

IPC: G01N35/10 ,  G01N21/64 ,  H04N7/18 ,  B01L3/02

Abstract: A device for determining a position and/or an extension of a drop in a position determination space, where the device has a camera having an objective and a beam splitter in the recording area of the camera, and the device is designed in such a way that light coming from the position determination space can enter the objective of the camera along a first light path as well as along a second light path, where light along the first light path can be reflected at a first reflector element in the direction of the beam splitter and can be transmitted through the beam splitter towards the objective, and where light along the second light path can be reflected at a second reflector element in the direction of the beam splitter and can be reflected at the beam splitter towards the objective.