公开(公告)号：US20150313498A1

公开(公告)日：2015-11-05

申请号：US14435398

申请日：2013-10-14

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  THE SALK INSTITUTE FOR BIOLOGICAL STUDIES

发明人： Todd Prentice Coleman ,  Rui Ma ,  Michael Bajema ,  Ricardo Gil Da Costa ,  Raynard Fung

IPC分类号： A61B5/0484 ,  A61B5/04 ,  A61B5/00 ,  A61B5/0478 ,  A61B5/0492

CPC分类号： A61B5/0478 ,  A61B5/04012 ,  A61B5/0482 ,  A61B5/0484 ,  A61B5/04842 ,  A61B5/04845 ,  A61B5/04847 ,  A61B5/0488 ,  A61B5/0492 ,  A61B5/165 ,  A61B5/167 ,  A61B5/168 ,  A61B5/6803 ,  A61B5/6814

摘要： Methods, systems, and devices are disclosed for acquiring and analyzing physiological signals. In one aspect, a physiological sensor device includes a substrate formed of an electrically insulative material and structured to allow physical contact of the device with the frontal region of the head of a user, a recording electrode configured at a first location on the substrate to acquire an electrophysiological signal of the user, a reference electrode configured at a second location on the substrate to acquire a reference signal to the electrophysiological signal, and a ground electrode configured at a third location at least partially between the first and the second locations on the substrate, in which the first location is posterior to the second and third locations, and in which the device is operable when electrically coupled to an electrical circuit to detect physiological signals of the user.

摘要翻译： 公开了用于获取和分析生理信号的方法，系统和装置。 一方面，一种生理传感器装置包括由电绝缘材料形成并被构造成允许该装置与使用者头部的前部区域的物理接触的记录电极，该记录电极配置在该基板上的第一位置以获得 用户的电生理信号，在基板上的第二位置处配置以获取对电生理信号的参考信号的参考电极，以及配置在第三位置处的至少部分地在衬底上的第一和第二位置之间的接地电极 ，其中所述第一位置位于所述第二和第三位置之后，并且其中所述装置在电耦合到电路以操作以检测所述用户的生理信号时可操作。

公开(公告)号：US10891313B2

公开(公告)日：2021-01-12

申请号：US15879396

申请日：2018-01-24

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  THE SALK INSTITUTE FOR BIOLOGICAL STUDIES

发明人： Todd Prentice Coleman ,  Rui Ma ,  Sanggyun Kim ,  Cheolsoo Park ,  Ricardo Gil Da Costa ,  Raynard Fung ,  Diego Mesa

IPC分类号： A61B5/0484 ,  G06F16/28 ,  G06F16/2457 ,  A61B5/0482 ,  G16H10/20 ,  A61B5/00 ,  A61B5/0488 ,  A61B5/16

摘要： Methods, devices, and systems are disclosed for producing cognitive and/or sensory profiles. In one aspect, a method to provide a cognitive or sensory assessment of a subject includes selecting a profile category from among a cognitive performance profile, a sensory performance profile, and a cognitive and sensory performance profile, presenting a sequence of stimuli to a subject, the sequence of stimuli based on the selected profile category, acquiring physiological signals of the subject before, during, and after the presenting the sequence of stimuli to produce physiological data, and processing the physiological data to generate an information set including one or more quantitative values associated with the selected profile category.

公开(公告)号：US20180285442A1

公开(公告)日：2018-10-04

申请号：US15879396

申请日：2018-01-24

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  THE SALK INSTITUTE FOR BIOLOGICAL STUDIES

发明人： Todd Prentice Coleman ,  Rui Ma ,  Sanggyun Kim ,  Cheolsoo Park ,  Ricardo Gil Da Costa ,  Raynard Fung ,  Diego Mesa

IPC分类号： G06F17/30 ,  A61B5/0482 ,  A61B5/0484 ,  G16H10/20 ,  A61B5/16 ,  A61B5/0488 ,  A61B5/00

摘要： Methods, devices, and systems are disclosed for producing cognitive and/or sensory profiles. In one aspect, a method to provide a cognitive or sensory assessment of a subject includes selecting a profile category from among a cognitive performance profile, a sensory performance profile, and a cognitive and sensory performance profile, presenting a sequence of stimuli to a subject, the sequence of stimuli based on the selected profile category, acquiring physiological signals of the subject before, during, and after the presenting the sequence of stimuli to produce physiological data, and processing the physiological data to generate an information set including one or more quantitative values associated with the selected profile category.

公开(公告)号：US09886493B2

公开(公告)日：2018-02-06

申请号：US14431734

申请日：2013-09-27

申请人： The Regents of the University of California ,  The Salk Institute for Biological Studies

发明人： Todd Prentice Coleman ,  Rui Ma ,  Sanggyun Kim ,  Cheolsoo Park ,  Ricardo Gil Da Costa ,  Raynard Fung ,  Diego Mesa

IPC分类号： A61B5/0482 ,  G06F17/30 ,  A61B5/0484 ,  G06F19/00 ,  A61B5/0488 ,  A61B5/16 ,  A61B5/00

CPC分类号： G06F17/30598 ,  A61B5/0482 ,  A61B5/0484 ,  A61B5/04842 ,  A61B5/04845 ,  A61B5/04847 ,  A61B5/0488 ,  A61B5/165 ,  A61B5/167 ,  A61B5/168 ,  A61B5/4011 ,  A61B5/4017 ,  A61B5/6814 ,  G06F17/3053 ,  G06F19/00 ,  G16H10/20

摘要： Methods, devices, and systems are disclosed for producing cognitive and/or sensory profiles. In one aspect, a method to provide a cognitive or sensory assessment of a subject includes selecting a profile category from among a cognitive performance profile, a sensory performance profile, and a cognitive and sensory performance profile, presenting a sequence of stimuli to a subject, the sequence of stimuli based on the selected profile category, acquiring physiological signals of the subject before, during, and after the presenting the sequence of stimuli to produce physiological data, and processing the physiological data to generate an information set including one or more quantitative values associated with the selected profile category.

公开(公告)号：US20150305686A1

公开(公告)日：2015-10-29

申请号：US14441826

申请日：2013-11-11

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  THE SALK INSTITUTE FOR BIOLOGICAL STUDIES

发明人： Todd Prentice Coleman ,  Marcela Mendoza ,  Justin Tantiongloc ,  Ricardo Gil Da Costa ,  Thomas D. Albright ,  Gene Stoner ,  Raynard Fung

IPC分类号： A61B5/00 ,  A61B5/0488 ,  A61B5/0478 ,  A61B5/16 ,  A61B5/0484

CPC分类号： A61B5/7275 ,  A61B5/0402 ,  A61B5/0478 ,  A61B5/0484 ,  A61B5/0488 ,  A61B5/165 ,  A61B5/168 ,  A61B5/4011 ,  A61B5/4017 ,  A61B5/4082 ,  A61B5/4088 ,  A61B5/4094 ,  A61B5/4848 ,  A61B5/7203 ,  A61B5/7264 ,  A61B2503/40 ,  G06F19/00

摘要： Methods, systems, and devices are disclosed for evaluating vulnerability, disease progression, and treatments in neuropathologies. In one aspect, a method to provide an assessment related to a neurological or neuropsychiatric disorder includes selecting a profile category indicative of one or more aspects of cognitive or sensory functions associated with a neurological or neuropsychiatric disorder, presenting a sequence of stimuli to a subject, in which the sequence of stimuli is based on the selected profile category, acquiring physiological signals of the subject before, during, and after the presenting of the sequence of stimuli to produce physiological data, and processing the physiological data to generate an information set including one or more quantitative values associated with the selected profile category.

摘要翻译： 公开了用于评估神经病理学中的脆弱性，疾病进展和治疗的方法，系统和装置。 在一个方面，提供与神经或神经精神障碍相关的评估的方法包括选择指示与神经系统或神经精神障碍相关的认知或感觉功能的一个或多个方面的概况类别，向受试者呈现刺激序列， 其中所述刺激序列基于所选择的分类类别，在呈现所述刺激序列之前，期间和之后获取所述对象的生理信号以产生生理数据，以及处理所述生理数据以生成包括一个的信息集 或更多与所选概要文件类别相关联的定量值。

公开(公告)号：US10258291B2

公开(公告)日：2019-04-16

申请号：US14441826

申请日：2013-11-11

申请人： The Regents of the University of California ,  The Salk Institute for Biological Studies

发明人： Todd Prentice Coleman ,  Marcela Mendoza ,  Justin Tantiongloc ,  Ricardo Gil Da Costa ,  Thomas D. Albright ,  Gene Stoner ,  Raynard Fung

IPC分类号： A61B5/0484 ,  A61B5/0488 ,  A61B5/0478 ,  A61B5/0402 ,  A61B5/00 ,  A61B5/16

摘要： Methods, systems, and devices are disclosed for evaluating vulnerability, disease progression, and treatments in neuropathologies. In one aspect, a method to provide an assessment related to a neurological or neuropsychiatric disorder includes selecting a profile category indicative of one or more aspects of cognitive or sensory functions associated with a neurological or neuropsychiatric disorder, presenting a sequence of stimuli to a subject, in which the sequence of stimuli is based on the selected profile category, acquiring physiological signals of the subject before, during, and after the presenting of the sequence of stimuli to produce physiological data, and processing the physiological data to generate an information set including one or more quantitative values associated with the selected profile category.

公开(公告)号：US10182736B2

公开(公告)日：2019-01-22

申请号：US14435398

申请日：2013-10-14

申请人： The Regents of the University of California ,  The Salk Institute for Biological Studies

发明人： Todd Prentice Coleman ,  Rui Ma ,  Michael Bajema ,  Ricardo Gil Da Costa ,  Raynard Fung

IPC分类号： A61B5/0478 ,  A61B5/0484 ,  A61B5/0492 ,  A61B5/00 ,  A61B5/04 ,  A61B5/0482 ,  A61B5/0488 ,  A61B5/16

摘要： Methods, systems, and devices are disclosed for acquiring and analyzing physiological signals. In one aspect, a physiological sensor device includes a substrate formed of an electrically insulative material and structured to allow physical contact of the device with the frontal region of the head of a user, a recording electrode configured at a first location on the substrate to acquire an electrophysiological signal of the user, a reference electrode configured at a second location on the substrate to acquire a reference signal to the electrophysiological signal, and a ground electrode configured at a third location at least partially between the first and the second locations on the substrate, in which the first location is posterior to the second and third locations, and in which the device is operable when electrically coupled to an electrical circuit to detect physiological signals of the user.

公开(公告)号：US20150248470A1

公开(公告)日：2015-09-03

申请号：US14431734

申请日：2013-09-27

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  THE SALK INSTITUTE FOR BIOLOGICAL STUDIES

发明人： Todd Prentice Coleman ,  Rui Ma ,  Sanggyun Kim ,  Cheolsoo Park ,  Ricardo Gil Da Costa ,  Raynard Fung ,  Diego Mesa

IPC分类号： G06F17/30 ,  G06F19/00

CPC分类号： G06F17/30598 ,  A61B5/0482 ,  A61B5/0484 ,  A61B5/04842 ,  A61B5/04845 ,  A61B5/04847 ,  A61B5/0488 ,  A61B5/165 ,  A61B5/167 ,  A61B5/168 ,  A61B5/4011 ,  A61B5/4017 ,  A61B5/6814 ,  G06F17/3053 ,  G06F19/00 ,  G16H10/20

摘要： Methods, devices, and systems are disclosed for producing cognitive and/or sensory profiles. In one aspect, a method to provide a cognitive or sensory assessment of a subject includes selecting a profile category from among a cognitive performance profile, a sensory performance profile, and a cognitive and sensory performance profile, presenting a sequence of stimuli to a subject, the sequence of stimuli based on the selected profile category, acquiring physiological signals of the subject before, during, and after the presenting the sequence of stimuli to produce physiological data, and processing the physiological data to generate an information set including one or more quantitative values associated with the selected profile category.

摘要翻译： 公开了用于产生认知和/或感觉简档的方法，装置和系统。 一方面，提供对受试者的认知或感官评估的方法包括从认知表现简档，感官表现简档以及认知和感觉性能轮廓中选择概况类别，向对象呈现刺激序列， 基于所选择的分类类别的刺激序列，在呈现所述刺激序列之前，之中和之后获取所述对象的生理信号以产生生理数据，以及处理所述生理数据以生成包括一个或多个定量值的信息集 与所选配置文件类别相关联。