公开(公告)号：US20160206969A1

公开(公告)日：2016-07-21

申请号：US14917268

申请日：2013-09-09

申请人： Yutaro KYONO ,  MOLCURE, INC.

发明人： Yutaro Kyono ,  Takuro Yonezawa

IPC分类号： A63H33/28 ,  G10L15/22 ,  H04N9/31 ,  G06F3/01 ,  A61B5/0476 ,  A42B1/00

CPC分类号： A63H33/28 ,  A42B1/004 ,  A61B5/0476 ,  A61B5/04847 ,  A63J5/02 ,  A63J5/021 ,  A63J5/025 ,  G06F3/015 ,  G06F3/167 ,  G09F19/12 ,  G09F19/18 ,  G10L15/22 ,  G10L15/26 ,  G10L2015/223 ,  H04N9/3173 ,  H04N9/3194

摘要： To expand an information-presenting capacity of soap bubble, a soap bubble-generating system includes: a fragrance generating unit which generates a fragrance; a soap film generating unit which generates a soap film; and a soap bubble generating unit which sprays a fragrance-containing gas toward the soap film to generate a soap bubble in which the fragrance is enclosed.

摘要翻译： 为了扩大肥皂泡的信息呈现能力，肥皂泡产生系统包括：产生香味的香味生成单元; 生成皂膜的皂膜发生单元; 以及肥皂泡产生单元，其向香皂膜喷射含香料的气体以产生香味被包封的皂泡。

公开(公告)号：US20160058392A1

公开(公告)日：2016-03-03

申请号：US14935718

申请日：2015-11-09

申请人： New York University ,  Yeda Research and Development Co., Ltd. at the Weizmann Institute of Science

发明人： URI HASSON ,  Rafi Malach ,  David Heeger

IPC分类号： A61B5/00 ,  A61B5/04 ,  A61B5/0484 ,  A61B5/11 ,  A61B3/113 ,  A61B6/03 ,  A61B3/11

CPC分类号： A61B5/7246 ,  A61B3/11 ,  A61B3/113 ,  A61B5/0042 ,  A61B5/0048 ,  A61B5/0075 ,  A61B5/04009 ,  A61B5/04842 ,  A61B5/04845 ,  A61B5/04847 ,  A61B5/055 ,  A61B5/1114 ,  A61B5/1128 ,  A61B6/037 ,  A61B2503/12

摘要： Exemplary embodiments of a system and method can be provided for measuring a level and/or details of how engaging, effective or memorable a stimulus that may be based on information associated with one or more subjects' neuronal, physiological and/or behavioral responses to the stimulus. In addition, an exemplary embodiment of a computer-accessible medium containing executable instructions thereon can also be provided which can be executed by a processing arrangement. For example, when the processing arrangement executes the instructions, the processing arrangement can be configured to, e.g., receive neuronal, physiological and/or behavioral data one or more subjects being presented with stimuli, determine further data associated with a measure of inter-subject similarity of the neuronal, physiological and/or behavioral data, and identify particular portions of the stimuli that meet a pre-determined criteria relating to the further data associated with the measure of inter-subject similarity. In addition, the processing arrangement can be further configured to display and/or store identifiers of the particular portions of the stimuli in a storage arrangement in a user-accessible format and/or a user-readable format.

摘要翻译： 可以提供系统和方法的示例性实施例，用于测量可以基于与一个或多个受试者的神经元，生理和/或行为反应相关联的信息的吸引，有效或难忘的刺激的水平和/或细节 刺激。 此外，还可以提供其上包含可执行指令的计算机可访问介质的示例性实施例，其可以由处理装置执行。 例如，当处理装置执行指令时，处理装置可以被配置为例如接收神经元，生理和/或行为数据，一个或多个被呈现刺激的对象，确定与对象间的度量相关联的进一步的数据 神经元，生理和/或行为数据的相似性，并且识别满足与与受试者间相似性的测量相关联的进一步数据相关的预定准则的刺激的特定部分。 此外，处理装置还可以被配置为以用户可访问的格式和/或用户可读格式在存储装置中显示和/或存储刺激的特定部分的标识符。

公开(公告)号：US20160015289A1

公开(公告)日：2016-01-21

申请号：US14772996

申请日：2014-03-06

申请人： Adam J. SIMON ,  Gary S. KATH ,  Cerora, Inc.

发明人： Adam J. SIMON ,  Gary S. KATH

IPC分类号： A61B5/0484 ,  A61B5/0478 ,  A61B5/16 ,  A61B7/04 ,  A61B5/026 ,  A61B3/14 ,  A61B5/00 ,  A61B5/04 ,  A61B5/1455 ,  A61B5/0205 ,  A61B3/113

CPC分类号： A61B5/04842 ,  A61B3/113 ,  A61B3/145 ,  A61B5/0002 ,  A61B5/0006 ,  A61B5/0057 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/02416 ,  A61B5/026 ,  A61B5/04012 ,  A61B5/0478 ,  A61B5/0484 ,  A61B5/04845 ,  A61B5/04847 ,  A61B5/0533 ,  A61B5/11 ,  A61B5/1103 ,  A61B5/1124 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/162 ,  A61B5/4041 ,  A61B5/4094 ,  A61B5/6803 ,  A61B5/681 ,  A61B5/6826 ,  A61B5/6898 ,  A61B5/7203 ,  A61B5/7246 ,  A61B5/7264 ,  A61B5/7275 ,  A61B5/744 ,  A61B7/04 ,  A61B2560/0443 ,  A61B2560/0475 ,  A61B2562/0204 ,  A61B2562/0219 ,  G16H15/00 ,  G16H20/70 ,  G16H40/63 ,  G16H40/67 ,  G16H50/20

摘要： A multi-modal physiological assessment device and method enables the simultaneous recording and then subsequent analysis of multiple data streams of biological signal measurements to assess the health and function of the brain. The multi-modal assessment system includes at least one channel of EEG brainwave data in combination with cognitive information that provide a two-dimensional data stream of (x(t), y(t)) of cognitive information; voice recordings; motion, position, and stability data; galvanic skin conductance; temperature of the subject; pulse-oximetry data, cerebral blood perfusion data, vaso-motor reactivity data, and the like. The collected data is processed to construct candidate features extracted from multiple biological sensor data streams and correlated with multi-modal signatures to identify data indicative of brain health, disease and injury.

摘要翻译： 多模式生理评估装置和方法能够同时记录并随后分析生物信号测量的多个数据流，以评估大脑的健康和功能。 多模式评估系统包括至少一个EEG脑波数据通道与认知信息的组合，提供认知信息的（x（t），y（t））的二维数据流; 录音; 运动，位置和稳定性数据; 电流皮肤电导; 受试者的温度; 脉搏血氧饱和度数据，脑血液灌注数据，血管运动反应性数据等。 处理收集的数据以构建从多个生物传感器数据流中提取的候选特征，并与多模式签名相关联以识别指示脑健康，疾病和损伤的数据。

公开(公告)号：US20150334990A1

公开(公告)日：2015-11-26

申请号：US14759084

申请日：2014-01-06

申请人： Golan NIR ,  Tamir GOREN

发明人： Golan NIR ,  Tamir GOREN

IPC分类号： A01K15/02 ,  A61B5/0205 ,  A61B5/024 ,  A61B5/16 ,  A61B5/00 ,  A61B5/0478 ,  A61B5/0484 ,  A01K1/00 ,  A61B5/11

CPC分类号： A01K15/02 ,  A01K1/00 ,  A61B5/0077 ,  A61B5/0205 ,  A61B5/024 ,  A61B5/0478 ,  A61B5/04847 ,  A61B5/11 ,  A61B2503/40

摘要： A biological sensor based system for detecting odors, which comprises (a) a compartment for completely or partially secluding and enclosing a biological sensor located therewithin that is configured to enable the biological sensor to perform normal animal motions as well as an odor detection operation; (b) an air inlet in the compartment through which odor laden flows into an interior of the compartment; (c) an air outlet through which the odor laden air is dischargeable from the compartment; (d) an animal depressible button which is movably connected to a wall of the compartment and is depressible by the biological sensor upon detection that the introduced odor is a predetermined target odor; (e) a force sensor connected to the button for sensing the pressing parameters applied by the biological sensor onto the pushbutton; (f) an analysis unit for determining whether the pressing parameters are within an expected range for the biological sensor and for transmitting an alert signal to a law enforcement entity or relevant official authorities when the pressing parameters are within the expected range and the pressing parameters are indicative of a known reaction of the biological sensor after detecting the predetermined target odor.

摘要翻译： 一种用于检测气味的基于生物传感器的系统，其包括（a）用于完全或部分地隔离并包围位于其中的生物传感器的隔室，所述生物传感器被配置为使生物传感器能够执行正常的动物运动以及气味检测操作; （b）室内的空气入口，气味通过该进气流入隔室的内部; （c）空气出口，通过该空气出口的气味可从隔室排出; （d）动物按压按钮，其可移动地连接到隔室的壁，并且在检测到所引入的气味是预定的目标气味时可被生物传感器压下; （e）连接到按钮的力传感器，用于感测由生物传感器施加到按钮上的按压参数; （f）分析单元，用于确定按压参数是否在生物传感器的预期范围内，并且当按压参数在预期范围内并且按压参数为...时，向执法实体或相关官方机构发送警报信号 指示在检测到预定目标气味之后生物传感器已知的反应。

公开(公告)号：US20080188729A1

公开(公告)日：2008-08-07

申请号：US12014311

申请日：2008-01-15

申请人： Hiroki Sato ,  Akiko Obata ,  Atsushi Maki ,  Kazutaka Ozaki ,  Takaomi Yasuhara ,  Ichiro Moda

发明人： Hiroki Sato ,  Akiko Obata ,  Atsushi Maki ,  Kazutaka Ozaki ,  Takaomi Yasuhara ,  Ichiro Moda

IPC分类号： A61B5/1455

CPC分类号： A61B5/4011 ,  A61B5/04842 ,  A61B5/04847 ,  A61B5/14553 ,  A61B5/4017 ,  A61B5/486

摘要： Appropriate measurement and analysis parameters are set according to cerebral function to be measured. To measure gustatory function, a time period of absence of cerebral activity to be measured is set so as not to contain a period of 60 seconds after start of stimulation, an activity period for analysis for an oxyhemoglobin concentration change signal is set so as to contain a period between an instant after a lapse of 16 seconds, and an instant after a lapse of 25 seconds, after the start of the stimulation, and an activity period for analysis for a deoxyhemoglobin concentration change signal is set so as to contain a period between an instant after a lapse of 28 seconds and an instant after a lapse of 37 seconds after the start of the stimulation. Moreover, a time interval between stimulations is set to 80 seconds or more.

摘要翻译： 根据要测量的脑功能设定适当的测量和分析参数。 为了测定放气功能，设定要测定的脑活动不存在的时间段，以使刺激开始后不含有60秒的期间，设定氧合血红蛋白浓度变化信号的分析活动期，使其含有 在经过16秒之后的瞬间与经过25秒之后的瞬间之间的时间之间，以及用于分析脱氧血红蛋白浓度改变信号的活动期间，设定为包含： 经过28秒之后的瞬间，以及在刺激开始后经过了37秒的瞬间。 此外，刺激之间的时间间隔设定为80秒以上。

公开(公告)号：US20020122770A1

公开(公告)日：2002-09-05

申请号：US10070170

申请日：2002-03-05

发明人： Hiroaki Oka ,  Ryuta Ogawa ,  Tetsuo Yukimasa

IPC分类号： A61K049/00 ,  A61B005/04

CPC分类号： G01N33/5088 ,  A01K1/031 ,  A01K29/005 ,  A61B5/0478 ,  A61B5/04847 ,  A61B5/4011 ,  A61B2562/0215 ,  A61B2562/046 ,  G01N2333/46

摘要： A method and apparatus for readily and reliably screening olfactory mucosa stimulating compounds are provided. An olfactory mucosa stimulating compound is sprayed through an atomizing nozzle 33 to an olfactory mucosa of a rat fixed in a test animal fixing device 32. A measuring electrode portion 10 is implanted in an olfactory bulb of the rat for measuring an electrical signal generated in the olfactory bulb. Efficacy of the olfactory mucosa stimulating compound is determined based on a correlation between an electrical signal measured by the measuring electrode portion 10 when the olfactory mucosa stimulating compound is sprayed on the olfactory mucosa of the rat and a physiological response induced in the rat.

摘要翻译： 提供了一种容易可靠地筛选嗅觉粘膜刺激化合物的方法和装置。 将嗅粘膜刺激化合物通过雾化喷嘴33喷射到固定在测试动物固定装置32中的大鼠的嗅粘膜上。测量电极部分10被植入大鼠的嗅球中，用于测量在 嗅球 基于当将嗅觉粘膜刺激化合物喷洒在大鼠的嗅粘膜上时由测量电极部分10测量的电信号与在大鼠中诱导的生理反应之间的相关性来确定嗅觉粘膜刺激化合物的功效。

公开(公告)号：US09826916B2

公开(公告)日：2017-11-28

申请号：US14432909

申请日：2013-10-02

申请人： FORSCHUNGSZENTRUM JÜLICH GMBH

发明人： Peter Alexander Tass

IPC分类号： A61B5/04 ,  A61B5/00 ,  A61N1/36 ,  A61B5/0484 ,  A61B5/0488 ,  A61B5/0478 ,  A61N1/05

CPC分类号： A61B5/04014 ,  A61B5/04009 ,  A61B5/0478 ,  A61B5/04842 ,  A61B5/04845 ,  A61B5/04847 ,  A61B5/0488 ,  A61B5/4064 ,  A61B5/4082 ,  A61B5/4094 ,  A61B5/7246 ,  A61B2562/0214 ,  A61N1/05 ,  A61N1/36025 ,  A61N1/3605

摘要： A device for examining a pathological interaction between different brain areas, including a stimulation unit, which administers identical stimuli to a patient in a sequential manner, wherein the stimuli stimulate neurons of the patient in the brain areas to be examined, a measuring unit for recording measurement signals that represent a neural activity of the stimulated neurons, and a control and analysis unit for controlling the stimulation unit and for analyzing the measurement signals. The control and analysis unit transforms the measurement signals into the complex plane, examines the distribution of the phases of stimuli of the measurement signals absorbed by the measuring unit in response to the stimuli delivered to the patient, and determines the probability, with which the phase distribution differs from a uniform distribution, in order to ascertain whether a pathological interaction between the brain areas exists.

公开(公告)号：US09179855B2

公开(公告)日：2015-11-10

申请号：US13285987

申请日：2011-10-31

申请人： Grigore C. Burdea ,  Bryan A. Rabin

发明人： Grigore C. Burdea ,  Bryan A. Rabin

IPC分类号： A61B5/04 ,  A61B5/0484 ,  A61B5/11 ,  A61B5/00 ,  A63F13/20 ,  A63F13/40 ,  A63B22/20 ,  A63B24/00 ,  A61B5/021 ,  A61B5/024 ,  A61B5/053 ,  A61B5/16 ,  A63B23/035 ,  A63B23/12 ,  A63B71/00 ,  A63B71/06

CPC分类号： A61B5/04 ,  A61B5/021 ,  A61B5/024 ,  A61B5/04842 ,  A61B5/04845 ,  A61B5/04847 ,  A61B5/0531 ,  A61B5/1104 ,  A61B5/165 ,  A61B5/4824 ,  A63B22/20 ,  A63B23/03508 ,  A63B23/03541 ,  A63B23/1209 ,  A63B24/0087 ,  A63B2024/0093 ,  A63B2024/0096 ,  A63B2071/0072 ,  A63B2071/0638 ,  A63B2071/0658 ,  A63B2220/13 ,  A63B2220/51 ,  A63B2220/70 ,  A63B2220/72 ,  A63B2220/76 ,  A63B2220/806 ,  A63B2225/20 ,  A63B2225/50 ,  A63B2230/062 ,  A63B2230/105 ,  A63B2230/425 ,  A63B2230/505 ,  A63B2230/655 ,  A63F13/06 ,  A63F13/10 ,  A63F13/212 ,  A63F13/67 ,  A63F2300/1012 ,  A63F2300/6027 ,  A63F2300/6045 ,  A63F2300/8094

摘要： Systems and methods for treating pain are described. Systems and methods for treating pain using video games, tilt tables and bio-sensors are described wherein the level of the video game is controlled by a computer based on the feedback from a patient. Corresponding systems are also disclosed.

摘要翻译： 描述了治疗疼痛的系统和方法。 描述了使用视频游戏，倾斜台和生物传感器来治疗疼痛的系统和方法，其中基于来自患者的反馈的计算机控制视频游戏的级别。 还公开了相应的系统。

公开(公告)号：US20150248470A1

公开(公告)日：2015-09-03

申请号：US14431734

申请日：2013-09-27

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  THE SALK INSTITUTE FOR BIOLOGICAL STUDIES

发明人： Todd Prentice Coleman ,  Rui Ma ,  Sanggyun Kim ,  Cheolsoo Park ,  Ricardo Gil Da Costa ,  Raynard Fung ,  Diego Mesa

IPC分类号： G06F17/30 ,  G06F19/00

CPC分类号： G06F17/30598 ,  A61B5/0482 ,  A61B5/0484 ,  A61B5/04842 ,  A61B5/04845 ,  A61B5/04847 ,  A61B5/0488 ,  A61B5/165 ,  A61B5/167 ,  A61B5/168 ,  A61B5/4011 ,  A61B5/4017 ,  A61B5/6814 ,  G06F17/3053 ,  G06F19/00 ,  G16H10/20

摘要： Methods, devices, and systems are disclosed for producing cognitive and/or sensory profiles. In one aspect, a method to provide a cognitive or sensory assessment of a subject includes selecting a profile category from among a cognitive performance profile, a sensory performance profile, and a cognitive and sensory performance profile, presenting a sequence of stimuli to a subject, the sequence of stimuli based on the selected profile category, acquiring physiological signals of the subject before, during, and after the presenting the sequence of stimuli to produce physiological data, and processing the physiological data to generate an information set including one or more quantitative values associated with the selected profile category.

摘要翻译： 公开了用于产生认知和/或感觉简档的方法，装置和系统。 一方面，提供对受试者的认知或感官评估的方法包括从认知表现简档，感官表现简档以及认知和感觉性能轮廓中选择概况类别，向对象呈现刺激序列， 基于所选择的分类类别的刺激序列，在呈现所述刺激序列之前，之中和之后获取所述对象的生理信号以产生生理数据，以及处理所述生理数据以生成包括一个或多个定量值的信息集 与所选配置文件类别相关联。

公开(公告)号：US20150230744A1

公开(公告)日：2015-08-20

申请号：US14420536

申请日：2013-08-09

申请人： VALORISATION-RECHERCHE, LIMITED PARTNERSHIP

发明人： Jocelyn Faubert ,  Claudine Habak ,  Rafael Doti ,  Jesus-Eduardo Lugo-Arce

IPC分类号： A61B5/1455 ,  A61B3/032 ,  A61B5/0484

CPC分类号： A61B5/14553 ,  A61B3/032 ,  A61B3/103 ,  A61B5/04842 ,  A61B5/04845 ,  A61B5/04847 ,  A61B5/6803

摘要： A method for assessing a subject perception of a stimulus property, comprising: applying to a subject at least a first sensory stimulus having a first value for the stimulus property and a second sensory stimulus having a second value for the stimulus property different from the first value; requesting the subject to identify a characteristic of the first and second sensory stimuli during the application thereof, the characteristic being unrelated to the stimulus property to be assessed, thereby focusing an attention of the subject on a decision making task; measuring an activity of at least one brain region of the subject during the application of the first and second sensorial stimuli and the identification of the characteristic thereof, thereby obtaining a brain activity measurement; and determining a difference of stimulus property perceived by the subject between the first and second sensory stimuli from the brain activity measurement.

摘要翻译： 一种用于评估刺激属性的受试者感知的方法，包括：向受试者施加至少具有刺激属性的第一值的第一感觉刺激和具有不同于第一值的刺激特性的第二值的第二感觉刺激 ; 要求受试者在施用期间识别第一和第二感觉刺激的特征，其特征与要评估的刺激性质无关，从而将受试者的注意力集中在决策任务上; 在施用第一和第二感觉刺激期间测量受试者的至少一个脑区域的活性并鉴定其特征，从而获得脑活动度量; 以及确定受试者在第一和第二感觉刺激之间从大脑活动测量中感觉到的刺激特性的差异。