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    SHAPE MEMORY POLYMER VESSEL OCCLUSION DEVICE
    4.
    发明申请
    SHAPE MEMORY POLYMER VESSEL OCCLUSION DEVICE 有权

    公开(公告)号：US20220323079A1

    公开(公告)日：2022-10-13

    申请号：US17846449

    申请日：2022-06-22

    申请人： THE TEXAS A&M UNIVERSITY SYSTEM ,  SHAPE MEMORY MEDICAL, INC.

    发明人： Duncan J. Maitland ,  Todd L. Landsman ,  Jennifer N. Rodriguez ,  Anthony J. Boyle ,  Alan C. Glowczwski ,  Mark A. Wierzbicki

    IPC分类号： A61B17/12

    摘要： An embodiment includes a system comprising: an outer conduit; a shape memory polymer (SMP) foam; a metal backbone including: (a)(i) a first portion that extends from the SMP foam proximal end to the SMP foam distal end and which is generally covered by the SMP foam, and (a)(ii) a distal portion that extends distally from the SMP foam distal end and which is not covered by the SMP foam; wherein: (b)(i) SMP foam and the metal backbone are both included within the outer conduit adjacent to the outer conduit distal end; (b)(ii) the metal backbone distal portion transitions from a secondary shape that is uncoiled to a primary shape that is coiled; and (b)(iii) the metal backbone distal portion is in the metal backbone distal portion secondary shape and is located between the SMP foam distal end and the distal end of the outer conduit.

    Shape memory polymer vessel occlusion device
    5.
    发明授权
    Shape memory polymer vessel occlusion device 有权

    公开(公告)号：US11369385B2

    公开(公告)日：2022-06-28

    申请号：US17032270

    申请日：2020-09-25

    申请人： THE TEXAS A&M UNIVERSITY SYSTEM ,  SHAPE MEMORY MEDICAL, INC

    发明人： Duncan J. Maitland ,  Todd L. Landsman ,  Jennifer N. Rodriguez ,  Anthony J. Boyle ,  Alan C. Glowczwski ,  Mark A. Wierzbicki

    IPC分类号： A61B17/12 ,  A61B17/00

    摘要： An embodiment includes a system comprising: an outer conduit; a shape memory polymer (SMP) foam; a metal backbone including: (a)(i) a first portion that extends from the SMP foam proximal end to the SMP foam distal end and which is generally covered by the SMP foam, and (a)(ii) a distal portion that extends distally from the SMP foam distal end and which is not covered by the SMP foam; wherein: (b)(i) SMP foam and the metal backbone are both included within the outer conduit adjacent to the outer conduit distal end; (b)(ii) the metal backbone distal portion transitions from a secondary shape that is uncoiled to a primary shape that is coiled; and (b)(iii) the metal backbone distal portion is in the metal backbone distal portion secondary shape and is located between the SMP foam distal end and the distal end of the outer conduit.

    Solvent depression of transition temperature to selectively stimulate actuation of shape memory polymer foams
    8.
    发明授权
    Solvent depression of transition temperature to selectively stimulate actuation of shape memory polymer foams 有权

    公开(公告)号：US11109869B2

    公开(公告)日：2021-09-07

    申请号：US16776638

    申请日：2020-01-30

    申请人： Lawrence Livermore National Security, LLC ,  The Texas A&M University System

    发明人： Anthony Boyle ,  Keith Hearon ,  Duncan J. Maitland ,  Landon D. Nash ,  Thomas S. Wilson

    IPC分类号： A61B17/12 ,  A61L31/06 ,  A61L31/14 ,  A61B17/00

    摘要： An embodiment of the invention is a shape memory polymer (SMP) foam designed to recover its original shape through exposure to a solvent. Thermo-responsive SMPs are polymers designed to maintain a programmed secondary shape until heated above their transition temperature, upon which the polymer recovers its original, or primary, shape. The thermo-responsive SMP foam is programmed to its secondary shape prior to use, typically compression of the foam to a small volume, and remains in this programmed shape until exposed to a selected solvent such as dimethyl sulfoxide or ethyl alcohol. Upon exposure to the solvent, the transition temperature of the SMP foam decreases below the temperature of the environment and the SMP foam actuates to its primary shape. The SMP foam is tailored to actuate upon exposure to specific solvents while minimizing or preventing actuation when exposed to water or other solvents. This selective solvent actuation can be used to increase working time of a SMP foam device, that is, the time allowed for use of a device without undesired actuation, while maintaining functional SMP actuation. Solvent actuated SMP foams can be used in various applications including, but not limited to, treatment of aneurysms and arterio-venous malformations, tissue engineering, and wound healing.