利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

17 条记录 (耗时 0.022 秒)

    GUANOSINE TRIPHOSPHATE (GTP)-BINDING PROTEIN-COUPLED RECEPTOR PROTEIN, BG37
    1.
    发明申请
    GUANOSINE TRIPHOSPHATE (GTP)-BINDING PROTEIN-COUPLED RECEPTOR PROTEIN, BG37 失效
    冠状三磷酸（GTP） - 蛋白质偶联受体蛋白BG37

    公开(公告)号：US20100184236A1

    公开(公告)日：2010-07-22

    申请号：US12716906

    申请日：2010-03-03

    申请人： TAKAHARU MARUYAMA ,  Takao Nakamura ,  Hiraku Itadani ,  Ken-Ichi Tanaka

    发明人： TAKAHARU MARUYAMA ,  Takao Nakamura ,  Hiraku Itadani ,  Ken-Ichi Tanaka

    IPC分类号： G01N33/566 ,  C07K14/435

    CPC分类号： C07K14/705

    摘要： The present inventors conducted a similarity search of the amino acid sequence of known G protein-coupled receptor proteins in GenBank, and obtained a novel human GPCR gene “BG37”, cDNA containing the ORF of the gene was cloned and its nucleotide sequence was determined. Moreover, novel GPCR “BG37” genes from mouse and rat were isolated. Use of the novel GPCR of the present invention enables screening of ligands, compounds inhibiting the binding to a ligand, and candidate compounds of pharmaceuticals which can regulate signal transduction from the “BG37” receptor.

    摘要翻译： 本发明人对GenBank中已知的G蛋白偶联受体蛋白质的氨基酸序列进行了相似检索，得到新的人GPCR基因“BG37”，克隆了含有该基因的ORF的cDNA，并测定其核苷酸序列。 此外，分离了来自小鼠和大鼠的新型GPCR“BG37”基因。 使用本发明的新型GPCR能够筛选配体，抑制与配体结合的化合物，以及可调节从“BG37”受体的信号转导的药物的候选化合物。

    Guanosine triphosphate (GTP)-binding protein-coupled receptor protein, BG37
    2.
    发明授权
    Guanosine triphosphate (GTP)-binding protein-coupled receptor protein, BG37 失效
    鸟苷三磷酸（GTP） - 结合蛋白偶联受体蛋白，BG37

    公开(公告)号：US07198914B2

    公开(公告)日：2007-04-03

    申请号：US10432101

    申请日：2001-10-30

    申请人： Takaharu Maruyama ,  Takao Nakamura ,  Hiraku Itadani ,  Ken-Ichi Tanaka

    发明人： Takaharu Maruyama ,  Takao Nakamura ,  Hiraku Itadani ,  Ken-Ichi Tanaka

    IPC分类号： C12P21/06 ,  C07K5/00

    CPC分类号： C07K14/705

    摘要： The present inventors conducted a similarity search of the amino acid sequence of known G protein-coupled receptor proteins in GenBank, and obtained a novel human GPCR gene “BG37”. cDNA containing the ORF of the gene was cloned and its nucleotide sequence was determined. Moreover, novel GPCR “BG37” genes from mouse and rat were isolated. Use of the novel GPCR of the present invention enables screening of ligands, compounds inhibiting the binding to a ligand, and candidate compounds of pharmaceuticals which can regulate signal transduction from the “BG37” receptor.

    摘要翻译： 本发明人对GenBank中已知的G蛋白偶联受体蛋白质的氨基酸序列进行了相似检索，得到了新的人GPCR基因“BG37”。 克隆含有该基因ORF的cDNA，测定其核苷酸序列。 此外，分离了来自小鼠和大鼠的新型GPCR“BG37”基因。 使用本发明的新型GPCR能够筛选配体，抑制与配体结合的化合物，以及可调节从“BG37”受体的信号转导的药物的候选化合物。

    Guanosine triphosphate (GTP)-binding protein-coupled receptor protein, BG37
    3.
    发明授权
    Guanosine triphosphate (GTP)-binding protein-coupled receptor protein, BG37 失效
    鸟苷三磷酸（GTP） - 结合蛋白偶联受体蛋白，BG37

    公开(公告)号：US08076455B2

    公开(公告)日：2011-12-13

    申请号：US12716906

    申请日：2010-03-03

    申请人： Takaharu Maruyama ,  Takao Nakamura ,  Hiraku Itadani ,  Ken-ichi Tanaka

    发明人： Takaharu Maruyama ,  Takao Nakamura ,  Hiraku Itadani ,  Ken-ichi Tanaka

    IPC分类号： C07K1/00 ,  G01N33/567

    CPC分类号： C07K14/705

    摘要： The present inventors conducted a similarity search of the amino acid sequence of known G protein-coupled receptor proteins in GenBank, and obtained a novel human GPCR gene “BG37”, cDNA containing the ORF of the gene was cloned and its nucleotide sequence was determined. Moreover, novel GPCR “BG37” genes from mouse and rat were isolated. Use of the novel GPCR of the present invention enables screening of ligands, compounds inhibiting the binding to a ligand, and candidate compounds of pharmaceuticals which can regulate signal transduction from the “BG37” receptor.

    摘要翻译： 本发明人对GenBank中已知的G蛋白偶联受体蛋白质的氨基酸序列进行了相似检索，得到新的人GPCR基因“BG37”，克隆了含有该基因的ORF的cDNA，并测定其核苷酸序列。 此外，分离了来自小鼠和大鼠的新型GPCR“BG37”基因。 使用本发明的新型GPCR能够筛选配体，抑制与配体结合的化合物，以及可调节从“BG37”受体的信号转导的药物的候选化合物。