公开(公告)号：US20100063000A1

公开(公告)日：2010-03-11

申请号：US12448591

申请日：2007-12-26

申请人： Takashi Furuyashiki ,  Hiroki Takata ,  Hideki Kajiura

发明人： Takashi Furuyashiki ,  Hiroki Takata ,  Hideki Kajiura

IPC分类号： A61K31/715 ,  A23L1/48 ,  C07H1/00

CPC分类号： A61K31/715 ,  A21D2/181 ,  A23K20/163 ,  A23K50/10 ,  A23K50/40 ,  A23L29/269 ,  A23L29/275 ,  A23L33/10 ,  A23V2002/00 ,  A23V2200/3202 ,  A23V2200/30

摘要： The object is to improve a blood glucose level, a visceral fat level, a blood cholesterol level, a neutral fat level and the like. Disclosed is a food containing glycogen as a carbohydrate. The food can be ingested to improve a blood glucose level, a visceral fat level, a blood cholesterol level, a neutral fat level and the like comprehensively.

摘要翻译： 目的是提高血糖水平，内脏脂肪水平，血液胆固醇水平，中性脂肪水平等。 公开了含有糖原作为碳水化合物的食物。 能够全面地摄取食物来提高血糖值，内脏脂肪含量，血液中胆固醇含量，中性脂肪含量等。

公开(公告)号：US08461130B2

公开(公告)日：2013-06-11

申请号：US12448591

申请日：2007-12-26

申请人： Takashi Furuyashiki ,  Hiroki Takata ,  Hideki Kajiura

发明人： Takashi Furuyashiki ,  Hiroki Takata ,  Hideki Kajiura

IPC分类号： A61K31/715 ,  A01N43/04

CPC分类号： A61K31/715 ,  A21D2/181 ,  A23K20/163 ,  A23K50/10 ,  A23K50/40 ,  A23L29/269 ,  A23L29/275 ,  A23L33/10 ,  A23V2002/00 ,  A23V2200/3202 ,  A23V2200/30

摘要： The present invention is directed towards improving blood glucose levels, visceral fat levels, blood cholesterol levels, neutral fat levels, etc. by oral administration of enzyme synthesized glycogen (ESG). The invention is further directed towards the intake of food by a subject that comprises ESG as a carbohydrate to improve blood glucose levels, visceral fat levels, blood cholesterol levels, neutral fat levels and the like.

摘要翻译： 本发明旨在通过口服施用酶合成糖原（ESG）来改善血糖水平，内脏脂肪水平，血液胆固醇水平，中性脂肪水平等。 本发明进一步涉及由包含ESG作为碳水化合物的受试者摄取食物以改善血糖水平，内脏脂肪水平，血液胆固醇水平，中性脂肪水平等。

公开(公告)号：US07670812B2

公开(公告)日：2010-03-02

申请号：US11575794

申请日：2005-09-28

申请人： Hideki Kajiura ,  Hiroki Takata ,  Takeshi Takaha ,  Takashi Kuriki

发明人： Hideki Kajiura ,  Hiroki Takata ,  Takeshi Takaha ,  Takashi Kuriki

IPC分类号： C12P19/04 ,  C12N9/00 ,  C12N9/10 ,  C12N1/20 ,  C12N15/00 ,  C07H21/04

CPC分类号： C12P19/04 ,  C12N9/2411 ,  C12P19/18

摘要： A method of producing glycogen comprising a step of: allowing a branching enzyme having the ability to synthesize glycogen to act on a substrate in a solution to produce a glycogen, wherein the substrate is an α-glucan being linked mainly with α-1,4-glucosidic bonds and having a degree of polymerization of 4 or more, and the number-average molecular weight of saccharides in the solution before initiation of the reaction is more than 180 but not more than 150,000. (The branching enzyme activity of the branching enzyme)/(the molecular-weight-decreasing activity of the branching enzyme) can be 500 or less. The branching enzyme can be a thermostable branching enzyme.

摘要翻译： 一种制备糖原的方法，包括以下步骤：使具有合成糖原的能力的分支酶作用于溶液中的底物以产生糖原，其中所述底物是α-葡聚糖主要与α-1,4 - 糖苷键，聚合度为4以上，反应开始前溶液中的糖类的数均分子量大于180，但不大于150,000。 （支化酶的分支酶活性）/（分支酶的分子量降低活性）可以为500以下。 分支酶可以是热稳定分支酶。

公开(公告)号：US20080131941A1

公开(公告)日：2008-06-05

申请号：US11575794

申请日：2005-09-28

申请人： Hideki Kajiura ,  Hiroki Takata ,  Takeshi Takaha ,  Takashi Kuriki

发明人： Hideki Kajiura ,  Hiroki Takata ,  Takeshi Takaha ,  Takashi Kuriki

IPC分类号： C12P19/04

CPC分类号： C12P19/04 ,  C12N9/2411 ,  C12P19/18

摘要： A method of producing glycogen comprising a step of: allowing a branching enzyme having the ability to synthesize glycogen to act on a substrate in a solution to produce a glycogen, wherein the substrate is an α-glucan being linked mainly with α-1,4-glucosidic bonds and having a degree of polymerization of 4 or more, and the number-average molecular weight of saccharides in the solution before initiation of the reaction is more than 180 but not more than 150,000. (The branching enzyme activity of the branching enzyme)/(the molecular-weight-decreasing activity of the branching enzyme) can be 500 or less. The branching enzyme can be a thermostable branching enzyme.

摘要翻译： 一种制备糖原的方法，包括以下步骤：使具有合成糖原的能力的分支酶在溶液中作用于底物以产生糖原，其中所述底物是主要与α-1,4连接的α-葡聚糖 - 糖苷键，聚合度为4以上，反应开始前溶液中的糖类的数均分子量大于180，但不大于150,000。 （支化酶的分支酶活性）/（分支酶的分子量降低活性）可以为500以下。 分支酶可以是热稳定分支酶。

公开(公告)号：US20080131945A1

公开(公告)日：2008-06-05

申请号：US10573718

申请日：2004-09-29

申请人： Tetsuo Toraya ,  Takamasa Tobimatsu ,  Mamoru Yamanishi ,  Kouichi Mori ,  Hideki Kajiura ,  Seiki Yamada ,  Michio Yuzuki ,  Muneaki Azuma ,  Tetsuya Hara ,  Shinzo Yasuda

发明人： Tetsuo Toraya ,  Takamasa Tobimatsu ,  Mamoru Yamanishi ,  Kouichi Mori ,  Hideki Kajiura ,  Seiki Yamada ,  Michio Yuzuki ,  Muneaki Azuma ,  Tetsuya Hara ,  Shinzo Yasuda

IPC分类号： C12P7/24 ,  C12P7/52

CPC分类号： C12P7/24 ,  C12P7/18 ,  C12P7/40 ,  C12P7/42 ,  C12P7/62

摘要： A method for producing 3-hydroxypropionaldehyde from glycerin in high conversion ratio is provided. The method is characterized by comprising a step of dehydrating glycerin using a microbial cell and/or a treated microbial cell containing diol dehydratase and/or glycerol dehydratase, and optionally diol dehydratase reactivating factor and/or glycerol dehydratase reactivating factor, under conditions so as to give a value (X/Y2) calculated by dividing a catalytic amount [X (U/g glycerin)] of diol dehydratase and/or glycerol dehydratase by square of glycerin concentration [Y (g/100 ml)] within a range of 10 to 8,000, to produce 3-hydroxypropionaldehyde.

摘要翻译： 提供了一种以高转化率从甘油生产3-羟基丙醛的方法。 该方法的特征在于包括使用微生物细胞和/或含有二醇脱水酶和/或甘油脱水酶的处理的微生物细胞和任选的二醇脱水酶再活化因子和/或甘油脱水酶再活化因子的甘油脱水甘油的步骤， 给出通过将二醇脱水酶和/或甘油脱水酶的催化量[X（U / g甘油）]除以甘油浓度平方[Y（g / 100）]计算的值（X / Y 2 ml）]在10至8,000的范围内，以产生3-羟基丙醛。