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公开(公告)号：US20080038289A1
公开(公告)日：2008-02-14
申请号：US11596395
申请日：2005-05-30
申请人： Takashi Kawai , Shigetoshi Mizutani , Tatsuji Enoki , Hiroaki Sagawa , Takeshi Sakai , Kazuo Shimanaka , Ikunoshin Kato
发明人： Takashi Kawai , Shigetoshi Mizutani , Tatsuji Enoki , Hiroaki Sagawa , Takeshi Sakai , Kazuo Shimanaka , Ikunoshin Kato
IPC分类号： A61K36/06 , A61K31/045 , A61P35/00
CPC分类号： A61K36/07 , A23L33/105 , A61K31/047
摘要： According to the present invention, an antitumor agent, an apoptosis-inducing agent or an angiogenesis-suppressing agent having the effect even via an oral route, containing a compound contained in an inexpensive edible basidiomycete or a composition derived from an edible basidiomycete, and a food having the antitumor activity, the apoptosis-inducing activity or the angiogenesis-suppressing activity containing the compound or the composition can be obtained. Therefore, the present invention is particularly useful, especially in the field of a medicine and a health food.
摘要翻译： 根据本发明，通过口服途径具有效果的抗肿瘤剂，细胞凋亡诱导剂或血管生成抑制剂，其含有廉价的可食用担子菌或含有可食用担子菌的组合物，以及 可以获得具有抗肿瘤活性，含有化合物或组合物的细胞凋亡诱导活性或血管生成抑制活性的食品。 因此，本发明特别有用，特别是在药物和保健食品领域。
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公开(公告)号：US07678368B2
公开(公告)日：2010-03-16
申请号：US11311341
申请日：2005-12-20
申请人： Shigetoshi Mizutani , Suzu Deguchi , Eiji Kobayashi , Eiji Nishiyama , Hiroaki Sagawa , Ikunoshin Kato
发明人： Shigetoshi Mizutani , Suzu Deguchi , Eiji Kobayashi , Eiji Nishiyama , Hiroaki Sagawa , Ikunoshin Kato
CPC分类号： A61Q19/10 , A61K8/60 , A61K8/73 , A61K8/9706 , A61K31/04 , A61K31/08 , A61K31/13 , A61K31/70 , A61K33/20 , A61Q5/00 , A61Q5/02 , A61Q7/00 , A61Q19/00 , A61Q19/005 , A61Q19/007 , A61Q19/08 , Y10S514/88
摘要： To find a substance which has a skin cosmeticizing effect such as prevention of skin aging, amelioriation of sensitive skin, or antipruritic action, and can serve as an effective ingredient for a hair-care product, thereby providing cosmetics comprising the effective ingredient. Concretely, there are provided cosmetics characterized in that the cosmetics comprise as an effective ingredient a compound selected from a fucoidan, a degradation product thereof, a sulfated monosaccharide or a salt thereof.
摘要翻译： 为了找到具有防止皮肤老化，敏感性皮肤的改善或止痒作用的皮肤美容效果的物质，可以作为护发品的有效成分，从而提供含有效成分的化妆品。 具体地，提供了化妆品，其特征在于，所述化妆品包含选自岩藻依聚糖，其降解产物，硫酸化单糖或其盐的化合物作为有效成分。
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公开(公告)号：US20060093566A1
公开(公告)日：2006-05-04
申请号：US11311341
申请日：2005-12-20
申请人： Shigetoshi Mizutani , Suzu Deguchi , Eiji Kobayashi , Eiji Nishiyama , Hiroaki Sagawa , Ikunoshin Kato
发明人： Shigetoshi Mizutani , Suzu Deguchi , Eiji Kobayashi , Eiji Nishiyama , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K8/73
CPC分类号： A61Q19/10 , A61K8/60 , A61K8/73 , A61K8/9706 , A61K31/04 , A61K31/08 , A61K31/13 , A61K31/70 , A61K33/20 , A61Q5/00 , A61Q5/02 , A61Q7/00 , A61Q19/00 , A61Q19/005 , A61Q19/007 , A61Q19/08 , Y10S514/88
摘要： To find a substance which has a skin cosmeticizing effect such as prevention of skin aging, amelioriation of sensitive skin, or antipruritic action, and can serve as an effective ingredient for a hair-care product, thereby providing cosmetics comprising the effective ingredient. Concretely, there are provided cosmetics characterized in that the cosmetics comprise as an effective ingredient a compound selected from a fucoidan, a degradation product thereof, a sulfated monosaccharide or a salt thereof.
摘要翻译： 为了找到具有防止皮肤老化，敏感性皮肤的改善或止痒作用的皮肤美容效果的物质，可以作为护发品的有效成分，从而提供含有效成分的化妆品。 具体地，提供了化妆品，其特征在于，所述化妆品包含选自岩藻依聚糖，其降解产物，硫酸化单糖或其盐的化合物作为有效成分。
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公开(公告)号：US20050276821A1
公开(公告)日：2005-12-15
申请号：US11119769
申请日：2005-05-03
申请人： Kazutoh Takesako , Shigetoshi Mizutani , Masahiro Endo , Junko Ogawa , Takashi Okado , Ikunoshin Kato
发明人： Kazutoh Takesako , Shigetoshi Mizutani , Masahiro Endo , Junko Ogawa , Takashi Okado , Ikunoshin Kato
IPC分类号： G01N33/50 , A61K38/00 , A61K39/00 , A61K49/00 , A61P13/02 , A61P15/00 , A61P31/04 , C07K14/40 , C07K16/14 , C12N5/10 , C12N15/09 , C12N15/31 , C12Q1/68 , G01N33/53 , G01N33/569 , C07H21/04 , C12N1/18 , C12N15/74
CPC分类号： C07K14/40 , A61K38/00 , A61K39/00 , Y10S530/824
摘要： To provide a novel antigenic protein and a nucleic acid encoding the antigenic protein, which are useful for prophylaxis, treatment and diagnosis of diseases caused by fungi including Candida albicans. An antigenic protein characterized in that the antigenic protein is recognized by antiserum derived from a mammal having Candida albicans-infection resistance; and a nucleic acid encoding an antigenic protein which is recognized by antiserum derived from a mammal having Candida albicans-infection resistance.
摘要翻译： 提供新型抗原蛋白和编码抗原蛋白的核酸，其可用于预防，治疗和诊断由真菌引起的疾病，包括白色念珠菌。 一种抗原蛋白，其特征在于抗原蛋白由来自具有白念珠菌感染抗性的哺乳动物的抗血清识别; 以及编码由来自具有白念珠菌感染抗性的哺乳动物的抗血清识别的抗原性蛋白质的核酸。
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公开(公告)号：US07070793B1
公开(公告)日：2006-07-04
申请号：US09509744
申请日：1998-09-28
申请人： Kazutoh Takesako , Shigetoshi Mizutani , Masahiro Endo , Junko Ogawa , Takashi Okado , Ikunoshin Kato
发明人： Kazutoh Takesako , Shigetoshi Mizutani , Masahiro Endo , Junko Ogawa , Takashi Okado , Ikunoshin Kato
CPC分类号： C07K14/40 , A61K38/00 , A61K39/00 , Y10S530/824
摘要： To provide a novel antigenic protein and a nucleic acid encoding the antigenic protein, which are useful for prophylaxis, treatment and diagnosis of diseases caused by fungi including Candida albicans. An antigenic protein characterized in that the antigenic protein is recognized by antiserum derived from a mammal having Candida albicans-infection resistance; and a nucleic acid encoding an antigenic protein which is recognized by antiserum derived from a mammal having Candida albicans-infection resistance.
摘要翻译： 提供新型抗原蛋白和编码抗原蛋白的核酸，其可用于预防，治疗和诊断由真菌引起的疾病，包括白色念珠菌。 一种抗原蛋白，其特征在于抗原蛋白由来自具有白念珠菌感染抗性的哺乳动物的抗血清识别; 以及编码由来自具有白念珠菌感染抗性的哺乳动物的抗血清识别的抗原性蛋白质的核酸。
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公开(公告)号：US07491511B2
公开(公告)日：2009-02-17
申请号：US11280416
申请日：2005-11-17
CPC分类号： C07K14/40 , A61K39/00 , A61K39/0002 , A61K39/35 , C07K14/37 , C12P21/00 , G01N33/56961 , Y10S435/921 , Y10S435/922
摘要： There can be provided a fungal antigen which is an insoluble fraction obtainable from fungal cells of which cell wall has been substantially removed or at least partially removed; a process for producing the same; a nucleic acid encoding the fungal antigen; a biologic product containing the fungal antigen; a method of stimulating immunological responses by using the biologic product; a method of suppressing allergic reaction to fungi in a vertebrate; and a method for diagnosing a disease caused by fungi in a vertebrate.
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公开(公告)号：US20060068448A1
公开(公告)日：2006-03-30
申请号：US11280416
申请日：2005-11-17
IPC分类号： G01N33/569 , C07H21/04 , C12Q1/68 , C12P21/06 , G01N33/53 , C12N15/74 , C12N1/18 , C07K14/40
CPC分类号： C07K14/40 , A61K39/00 , A61K39/0002 , A61K39/35 , C07K14/37 , C12P21/00 , G01N33/56961 , Y10S435/921 , Y10S435/922
摘要： There can be provided a fungal antigen which is an insoluble fraction obtainable from fungal cells of which cell wall has been substantially removed or at least partially removed; a process for producing the same; a nucleic acid encoding the fungal antigen; a biologic product containing the fungal antigen; a method of stimulating immunological responses by using the biologic product; a method of suppressing allergic reaction to fungi in a vertebrate; and a method for diagnosing a disease caused by fungi in a vertebrate.
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公开(公告)号：US06333164B1
公开(公告)日：2001-12-25
申请号：US09262856
申请日：1999-03-04
IPC分类号： G01N33569
CPC分类号： C07K14/40 , A61K39/00 , A61K39/0002 , A61K39/35 , C07K14/37 , C12P21/00 , G01N33/56961 , Y10S435/921 , Y10S435/922
摘要： There can be provided a fungal antigen which is an insoluble fraction obtainable from fungal cells of which cell wall has been substantially removed or at least partially removed; a process for producing the same; a nucleic acid encoding the fungal antigen; a biologic product containing the fungal antigen; a method of stimulating immunological responses by using the biologic product; a method of suppressing allergic reaction to fungi in a vertebrate; and a method for diagnosing a disease caused by fungi in a vertebrate.
摘要翻译： 可以提供真菌抗原，其是可从真菌细胞获得的不溶性级分，其中细胞壁基本上被除去或至少部分去除; 其制造方法; 编码真菌抗原的核酸; 含有真菌抗原的生物制品; 通过使用生物制品刺激免疫反应的方法; 抑制脊椎动物对真菌的过敏反应的方法; 以及用于诊断由脊椎动物中的真菌引起的疾病的方法。
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