公开(公告)号：US20070038267A1

公开(公告)日：2007-02-15

申请号：US11502413

申请日：2006-08-11

Applicant: Kenzo Shodo ,  Akihiro Uehara ,  Jun Ohta ,  Takashi Tokuda

Inventor： Kenzo Shodo ,  Akihiro Uehara ,  Jun Ohta ,  Takashi Tokuda

IPC: A61N1/32

CPC classification number: A61N1/0543 ,  A61N1/36046 ,  A61N1/36185

Abstract: A vision regeneration assisting apparatus includes: a substrate which is to be placed in a body of a patient; a plurality of electrode groups each having a plurality of electrodes which are arranged on the substrate, the electrodes applying electrical stimulation pulse signals to cells forming a retina of the patient; and a plurality of switch units which are arranged on the substrate and of which one is provided for each electrode group, the switch units selectively switching output of the electrical stimulation pulse signals from each of the electrodes.

Abstract translation: 视觉再生辅助装置包括：待置于患者体内的基底; 多个电极组，每个具有布置在所述基板上的多个电极，所述电极将电刺激脉冲信号施加到形成患者视网膜的细胞; 以及多个开关单元，其布置在基板上，并且为每个电极组提供一个开关单元，开关单元选择性地切换来自每个电极的电刺激脉冲信号的输出。

公开(公告)号：US20050004626A1

公开(公告)日：2005-01-06

申请号：US10876530

申请日：2004-06-28

Applicant: Yasuo Terasawa ,  Hiroyuki Tashiro ,  Kenzo Shodo ,  Jun Ohta ,  Takashi Tokuda ,  Keiichiro Kagawa ,  Akihiro Uehara ,  Toru Yagi

Inventor： Yasuo Terasawa ,  Hiroyuki Tashiro ,  Kenzo Shodo ,  Jun Ohta ,  Takashi Tokuda ,  Keiichiro Kagawa ,  Akihiro Uehara ,  Toru Yagi

IPC: A61F9/08 ,  A61N1/05 ,  A61N1/36 ,  A61N1/18

CPC classification number: A61N1/36046

Abstract: A visual restoration aiding device for restoring vision of a patient comprises: a plurality of substrates which are placed on or under a retina of a patient's eye; a plurality of electrodes which are mounted on each substrate to apply an electrical stimulation pulse signal to cells constituting the retina; and a connecting unit which has flexibility and connects the substrates.

Abstract translation: 用于恢复患者视力的视觉恢复辅助装置包括：放置在患者眼睛的视网膜上或下面的多个基底; 多个电极，安装在每个基板上，以将电刺激脉冲信号施加到构成视网膜的细胞; 以及具有柔性并连接基板的连接单元。

公开(公告)号：US07968833B2

公开(公告)日：2011-06-28

申请号：US12226687

申请日：2007-04-12

Applicant: Takashi Tokuda ,  Jun Ohta

Inventor： Takashi Tokuda ,  Jun Ohta

IPC: H01L31/042

CPC classification number: H01L27/14623 ,  G01N27/3275 ,  H01L27/14603 ,  H01L27/14609 ,  H01L27/14634 ,  H01L27/14636

Abstract: The uppermost metallic wiring layer in light-blocking layers constituted by multilevel metallic wiring that prevents light from impinging on areas other than the light-receiving area of a photodiode in each picture cell is used as a measurement electrode to be directly contacted with a specimen to measure electrical signals. Furthermore, in each picture cell including a circuit for reading out electrical signals collected through the measurement electrode, another circuit for reading out electrical signals generated by the photodiode is provided in an independent or shared form. This configuration enables the photodiode for optical measurements and the measurement electrode for electrical measurements to be provided in every picture cell. Thus, in a hybrid image sensor having an optical measurement function for obtaining optical information due to specimen and an electrical measurement functions for obtaining electrical information due to the specimen, the spatial resolution of both types of two-dimensional images can be simultaneously improved.

Abstract translation: 作为测定用电极，与被检体直接接触，使用由多层金属布线构成的遮光层中最上层的金属布线层，该多层金属布线防止光照射到各图像单元的光电二极管的受光面以外的区域 测量电信号。 此外，在包括用于读取通过测量电极收集的电信号的电路的每个图像单元中，用于读出由光电二极管产生的电信号的另一电路以独立或共享的形式提供。 该配置使得能够在每个图像单元中提供用于光学测量的光电二极管和用于电测量的测量电极。 因此，在具有用于获取样本的光学信息的光学测量功能的混合图像传感器和用于获得由于样本导致的电信息的电测量功能的情况下，可以同时提高两种类型的二维图像的空间分辨率。

公开(公告)号：US20090166514A1

公开(公告)日：2009-07-02

申请号：US12226687

申请日：2007-04-12

Applicant: Takashi Tokuda ,  Jun Ohta

Inventor： Takashi Tokuda ,  Jun Ohta

IPC: H01L31/042 ,  H01L31/0224

CPC classification number: H01L27/14623 ,  G01N27/3275 ,  H01L27/14603 ,  H01L27/14609 ,  H01L27/14634 ,  H01L27/14636

Abstract: The uppermost metallic wiring layer in light-blocking layers constituted by multilevel metallic wiring that prevents light from impinging on areas other than the light-receiving area of a photodiode in each picture cell is used as a measurement electrode to be directly contacted with a specimen to measure electrical signals. Furthermore, in each picture cell including a circuit for reading out electrical signals collected through the measurement electrode, another circuit for reading out electrical signals generated by the photodiode is provided in an independent or shared form. This configuration enables the photodiode for optical measurements and the measurement electrode for electrical measurements to be provided in every picture cell. Thus, in a hybrid image sensor having an optical measurement function for obtaining optical information due to specimen and an electrical measurement functions for obtaining electrical information due to the specimen, the spatial resolution of both types of two-dimensional images can be simultaneously improved.

Abstract translation: 作为测定用电极，与被检体直接接触，使用由多层金属布线构成的遮光层中最上层的金属布线层，该多层金属布线防止光照射到各图像单元的光电二极管的受光面以外的区域 测量电信号。 此外，在包括用于读取通过测量电极收集的电信号的电路的每个图像单元中，用于读出由光电二极管产生的电信号的另一电路以独立或共享的形式提供。 该配置使得能够在每个图像单元中提供用于光学测量的光电二极管和用于电测量的测量电极。 因此，在具有用于获取样本的光学信息的光学测量功能的混合图像传感器和用于获得由于样本导致的电信息的电测量功能的情况下，可以同时提高两种类型的二维图像的空间分辨率。

公开(公告)号：US07337008B2

公开(公告)日：2008-02-26

申请号：US10876530

申请日：2004-06-28

Applicant: Yasuo Terasawa ,  Hiroyuki Tashiro ,  Kenzo Shodo ,  Jun Ohta ,  Takashi Tokuda ,  Keiichiro Kagawa ,  Akihiro Uehara ,  Toru Yagi

Inventor： Yasuo Terasawa ,  Hiroyuki Tashiro ,  Kenzo Shodo ,  Jun Ohta ,  Takashi Tokuda ,  Keiichiro Kagawa ,  Akihiro Uehara ,  Toru Yagi

IPC: A61N1/18

CPC classification number: A61N1/36046

Abstract: A visual restoration aiding device for restoring vision of a patient comprises: a plurality of substrates which are placed on or under a retina of a patient's eye; a plurality of electrodes which are mounted on each substrate to apply an electrical stimulation pulse signal to cells constituting the retina; and a connecting unit which has flexibility and connects the substrates.

Abstract translation: 用于恢复患者视力的视觉恢复辅助装置包括：放置在患者眼睛的视网膜上或下面的多个基底; 多个电极，安装在每个基板上，以将电刺激脉冲信号施加到构成视网膜的细胞; 以及具有柔性并连接基板的连接单元。

公开(公告)号：US08874201B2

公开(公告)日：2014-10-28

申请号：US13121506

申请日：2009-09-25

Applicant: Takashi Tokuda ,  Jun Ohta

Inventor： Takashi Tokuda ,  Jun Ohta

IPC: A61B5/0476 ,  A61B5/0478 ,  A61B5/00 ,  A61B5/04 ,  A61B5/0492

CPC classification number: A61B5/04001 ,  A61B5/0086 ,  A61B5/0478 ,  A61B5/0492 ,  A61B5/4064

Abstract: An intracerebral information measuring device which can be mounted on the head of a subject by simple surgery and which attains measurement of low invasion, high sensitivity, and high resolution is provided. An internally mounted unit is composed of a probe section to be inserted in the brain through a hole having a small diameter bored in the skull of the subject, and a head section integrated with the probe section and to be disposed between the skull and the scalp. The probe section includes an electrode for sensing an action potential. The head section includes a transmitter for wirelessly transmitting signals captured with the electrode to the outside. On the outside of the head, an external measuring unit for receiving the signal transmitted from the head section and reproducing the original signal is provided.

Abstract translation: 提供了可以通过简单的手术安装在受试者的头部并且具有低入侵，高灵敏度和高分辨率的测量的脑内信息测量装置。 内部安装的单元由探针部分组成，该探头部分通过在被检体的头骨中钻孔的小直径插入脑内，头部与探头部一体化并设置在颅骨与头皮之间 。 探针部分包括用于感测动作电位的电极。 头部包括用于将用电极捕获的信号无线传输到外部的发射器。 在头部的外侧，提供用于接收从头部发送的信号并再现原始信号的外部测量单元。

公开(公告)号：US20110178422A1

公开(公告)日：2011-07-21

申请号：US13121506

申请日：2009-09-25

Applicant: Takashi Tokuda ,  Jun Ohta

Inventor： Takashi Tokuda ,  Jun Ohta

IPC: A61B5/0476

CPC classification number: A61B5/04001 ,  A61B5/0086 ,  A61B5/0478 ,  A61B5/0492 ,  A61B5/4064

Abstract: An intracerebral information measuring device which can be mounted on the head of a subject by simple surgery and which attains measurement of low invasion, high sensitivity, and high resolution is provided. An internally mounted unit is composed of a probe to be inserted in the brain through a hole having a small diameter bored in the skull of the subject, and a head section integrated with the probe section and to be disposed between the skull and the scalp. The probe section includes an electrode for sensing an action potential. The head section includes a transmitter for wirelessly transmitting signals captured with the electrode to the outside. On the outside of the head, an external measuring unit for receiving the signal transmitted from the head section and reproducing the original signal is provided.

Abstract translation: 提供了可以通过简单的手术安装在受试者的头部并且具有低入侵，高灵敏度和高分辨率的测量的脑内信息测量装置。 内部安装的单元由通过在被检体的头骨中钻孔的小直径的孔插入脑内的探针构成，头部与探头部一体化，并设置在颅骨与头皮之间。 探针部分包括用于感测动作电位的电极。 头部包括用于将用电极捕获的信号无线传输到外部的发射器。 在头部的外侧，提供用于接收从头部发送的信号并再现原始信号的外部测量单元。

公开(公告)号：US07923674B2

公开(公告)日：2011-04-12

申请号：US11922592

申请日：2006-06-06

Applicant: Keiichiro Kagawa ,  Jun Ohta

Inventor： Keiichiro Kagawa ,  Jun Ohta

IPC: H01L27/00

CPC classification number: H04N5/23241 ,  H01L27/14609 ,  H01L27/14643 ,  H04N5/3698 ,  H04N5/37455 ,  H04N5/378

Abstract: After resetting the potential VPD of the photodiode (11) to the predetermined potential VRST, light is incident onto the photodiode (11) for a predetermined period to decrease the VPD corresponding to the amount of the incident light. After that, a declivous ramp voltage VRAMP is applied to the source terminal of the first MOS transistor (12) which is a common-source amplifier for reading out the VPD. When the voltage difference between the gate and source of the MOS transistor (12) exceeds a threshold voltage, the MOS transistor is turned on and the output suddenly decreases. If a signal having a pulse width from the starting point of the sweep of the ramp voltage to the sudden lowering point of the output is generated, the pulse width depends on the amount of the incident light. With the signal readout of this PWM method, it is possible to lower the power consumption while a wide dynamic range is maintained, and to downsize the picture cells to achieve a higher number of picture cells.

Abstract translation: 在将光电二极管（11）的潜在VPD复位到预定电位VRST之后，光入射到光电二极管（11）上一段预定的时间以减小对应于入射光量的VPD。 之后，向作为用于读出VPD的公共源放大器的第一MOS晶体管（12）的源极端子施加斜率斜坡电压VRAMP。 当MOS晶体管（12）的栅极和源极之间的电压差超过阈值电压时，MOS晶体管导通，输出突然降低。 如果产生具有从斜坡电压的扫描的起始点到输出的突然降低点的脉冲宽度的信号，则脉冲宽度取决于入射光的量。 利用该PWM方法的信号读出，可以在维持宽的动态范围的同时降低功耗，并且可以减小图像单元以实现更高数量的图像单元。

公开(公告)号：US07308315B2

公开(公告)日：2007-12-11

申请号：US10467916

申请日：2002-02-14

Applicant: Jun Ohta ,  Shigeru Nishimura ,  Kohtaro Idegami ,  Keiichiro Kagawa

Inventor： Jun Ohta ,  Shigeru Nishimura ,  Kohtaro Idegami ,  Keiichiro Kagawa

IPC: A61N1/00

CPC classification number: A61F9/0017 ,  A61F9/08

Abstract: It is an object of the invention to provide a vision regeneration assisting apparatus capable of assisting in vision regeneration without making a system structure complicated.In the invention, a vision regeneration assisting apparatus for regenerating a vision of a patient going blind by a disease of a retina includes a photosensor embedded in the retina of an eye of the patient and converting an optical signal into an electric signal, photographing means for photographing an object to be recognized by the patient, image processing means for carrying out an image processing to extract a feature with respect to an image of the object obtained by the photographing means, pulse light forming means for forming a luminous flux into a pulse light to induce a vision, and irradiating means provided before the eye of the patient and applying the pulse light toward the photosensor so as to be formed as an image processed by the image processing means.

Abstract translation: 本发明的目的是提供一种能够辅助视觉再现而不使系统结构复杂化的视觉再生辅助装置。 在本发明中，视网膜再生辅助装置，用于再生由视网膜疾病失明的患者的视力，包括嵌入在患者眼睛的视网膜中的光传感器，并将光信号转换为电信号，拍摄装置 拍摄要被患者识别的对象，图像处理装置，用于执行图像处理以提取关于由拍摄装置获得的对象的图像的特征;脉冲光形成装置，用于将光束形成为脉冲光 以引起视力，以及设置在患者眼睛之前的照射装置，并将脉冲光施加到光传感器，以形成为由图像处理装置处理的图像。

公开(公告)号：US5095459A

公开(公告)日：1992-03-10

申请号：US375813

申请日：1989-07-05

Applicant: Jun Ohta ,  Kazuo Kyuma ,  Shuichi Tai ,  Masaya Oita

Inventor： Jun Ohta ,  Kazuo Kyuma ,  Shuichi Tai ,  Masaya Oita

IPC: G06K9/74 ,  G06N3/067

CPC classification number: G06K9/74 ,  G06N3/067

Abstract: An optical neural network which imitates a biological neural network, to provide an associative and/or pattern recognition function, is made of light emitting elements to represent an input neuron state vector, a correlation matrix which modulates light according to stored vector information, light receiving elements, an accumulator and a comparator to perform a threshold function. A stored vector closest to an input vector can be found from a large amount of information without increasing the system size by dividing the correlation matrix and the input neuron state vector with time division techniques, frequency modulation or phase modulation techniques. Positive and negative valves can also be provided with similar techniques.

Abstract translation: 模拟生物神经网络以提供关联和/或模式识别功能的光学神经网络由发光元件构成，以表示输入神经元状态向量，根据存储的矢量信息调制光的相关矩阵，光接收 元素，累加器和比较器来执行阈值函数。 可以从大量信息找到最接近输入向量的存储向量，而不需要通过用相关矩阵和输入神经元状态向量与时分技术，频率调制或相位调制技术相除来增加系统大小。 正极和负极阀也可以提供类似的技术。