4-alkylresorcinol derivative and external preparation for skin containing the same
    4.
    发明授权
    4-alkylresorcinol derivative and external preparation for skin containing the same 有权
    4-烷基间苯二酚衍生物和含有其的皮肤外用剂

    公开(公告)号:US08486919B2

    公开(公告)日:2013-07-16

    申请号:US13809696

    申请日:2011-06-01

    IPC分类号: A61K31/6615 C07F9/12

    摘要: The present invention provides a compound that has a high whitening effect and is excellent in safety and stability and provides an external preparation for skin comprising the same. The compound of the present invention is a 4-alkylresorcinol derivative represented by formula (1) or a salt thereof: wherein R1 is a branched or cyclic alkyl group of 3 to 7 carbon atoms or a linear alkyl group of 2 to 5 carbon atoms; R2 and R3 are each independently a hydrogen atom or a group represented by —P(O)(OR4)(OR5), and at least one of R2 and R3 is a group represented by —P(O)(OR4)(OR5); and R4 and R5 are each independently a hydrogen atom or a linear or branched alkyl group of 2 to 5 carbon atoms.

    摘要翻译: 本发明提供了具有高白化效果并且安全性和稳定性优异的化合物,并且提供了包含其的皮肤外用剂。 本发明的化合物是式(1)表示的4-烷基间苯二酚衍生物或其盐:其中,R 1为碳原子数3〜7的支链或环状烷基或碳原子数2〜5的直链烷基; R 2和R 3各自独立地为氢原子或由-P(O)(OR 4)(OR 5)表示的基团,R 2和R 3中的至少一个为-P(O)(OR 4)(OR 5) ; R 4和R 5各自独立地为氢原子或2〜5个碳原子的直链或支链烷基。

    SKIN-WHITENING AGENT AND COSMETIC METHOD FOR WHITENING SKIN
    6.
    发明申请
    SKIN-WHITENING AGENT AND COSMETIC METHOD FOR WHITENING SKIN 审中-公开
    用于白化皮肤的皮肤白化剂和化妆方法

    公开(公告)号:US20120122951A1

    公开(公告)日:2012-05-17

    申请号:US13138787

    申请日:2010-03-04

    摘要: The development of a skin-whitening agent which has a lower molecular weight, can be synthesized through a fewer steps and can be produced at low cost has been demanded. Thus, it is provided by the present invention a skin-whitening agent including one or more compounds selected from the group consisting of 4-cis-hydroxyproline and its derivative and/or its salt, a skin-whitening composition for external formulation to the skin, a cosmetic composition and a pharmaceutical composition, each of which contains the skin-whitening agent of the invention, and a cosmetic method for whitening the skin, which includes a step of administering one or more compounds selected from the group consisting of 4-cis-hydroxyproline and its derivative and/or its salt. In the skin-whitening agent and the cosmetic method for whitening the skin of the invention, the 4-cis-hydroxyproline may be 4-cis-L-hydroxyproline and/or 4-cis-D-hydroxyproline.

    摘要翻译: 需要开发具有较低分子量的皮肤增白剂,可以通过较少的步骤合成并且可以以低成本生产。 因此,本发明提供一种皮肤增白剂,其包含一种或多种选自4-顺式 - 羟基脯氨酸及其衍生物和/或其盐的化合物,用于皮肤外用制剂的皮肤增白组合物 ,化妆品组合物和药物组合物,其含有本发明的皮肤增白剂和美白化妆品的方法,其包括给予一种或多种选自4-顺式 - 羟脯氨酸及其衍生物和/或其盐。 在本发明的皮肤美白剂和美白化妆品的美白方法中,4-顺式 - 羟基脯氨酸可以是4-顺式-L-羟基脯氨酸和/或4-顺式-D-羟基脯氨酸。

    Connector unit for differential transmission
    7.
    发明授权
    Connector unit for differential transmission 失效
    用于差速传动的连接器单元

    公开(公告)号:US08152539B2

    公开(公告)日:2012-04-10

    申请号:US12346951

    申请日:2008-12-31

    IPC分类号: H01R4/66 H01R13/648

    摘要: A differential transmission connector unit is disclosed that includes a first differential transmission connector including a first electrically insulating block body; and first signal contact pairs and first ground contacts arranged alternately in a row in the first block body; and a second differential transmission connector including a second electrically insulating block body; and second signal contact pairs and second ground contacts arranged alternately in a row in the second block body. The first differential transmission connector is connected to the second differential transmission connector with the first signal contact pairs and the second signal contact pairs being in contact with each other and the first ground contacts and the second ground contacts being in contact with each other. One of the contact surface of each first ground contact and the contact surface of the corresponding second ground contact is a rolled surface, the contact surfaces contacting each other.

    摘要翻译: 公开了一种差分传输连接器单元,其包括:第一差分传输连接器,包括第一电绝缘块体; 以及在所述第一块体中交替布置的第一信号触点对和第一接地触点; 以及包括第二电绝缘块体的第二差分传输连接器; 以及第二信号接触对和第二接地触头,其在第二块体中交替布置成一行。 第一差分传输连接器与第二差分传输连接器连接,其中第一信号接触对和第二信号接触对彼此接触,并且第一接地触点和第二接地触点彼此接触。 每个第一接地触点的接触表面和相应的第二接地触点的接触表面之一是轧制表面,接触表面彼此接触。