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    Blood analyzer, blood analyzing method, and computer program product
    3.
    发明授权
    Blood analyzer, blood analyzing method, and computer program product 有权
    血液分析仪，血液分析法，计算机程序产品

    公开(公告)号：US09453790B2

    公开(公告)日：2016-09-27

    申请号：US12729989

    申请日：2010-03-23

    申请人： Ayumu Yoshida ,  Shinichiro Oguni ,  Tatsuya Narikawa ,  Saori Suzuki

    发明人： Ayumu Yoshida ,  Shinichiro Oguni ,  Tatsuya Narikawa ,  Saori Suzuki

    IPC分类号： G01N15/06 ,  G01N33/00 ,  G01N27/00 ,  G01N21/00 ,  G01N15/14 ,  G01N15/10

    CPC分类号： G01N15/1459 ,  G01N2015/1006 ,  G01N2015/1402

    摘要： A blood analyzer comprising: a specimen preparation section for preparing a measurement specimen that is used to measure a white blood cell count among CBC measurement items; a measurement section for obtaining optical information from blood cells contained in the measurement specimen; and a controller carrying out operations comprising: classifying blood cells contained in the measurement specimen into at least white blood cells and blood cells suspected to be abnormal blood cells based on the optical information; obtaining distribution data of the white blood cells and distribution data of the blood cells suspected to be abnormal blood cells; counting the white blood cells based on the distribution data of the white blood cells; and determining presence or absence of the abnormal blood cells in the blood sample, based on the distribution data of the blood cells suspected to be abnormal blood cells. A blood analyzing method and a computer program product are also disclosed.

    摘要翻译： 1.一种血液分析装置，其特征在于，具备：准备用于测定CBC测定项目中的白细胞计数的测定试样的检体准备部， 测量部分，用于从测量样本中包含的血球获得光学信息; 以及控制器，其执行操作包括：基于所述光学信息将包含在所述测量样本中的血球细胞分类为怀疑是异常血细胞的至少白血球和血细胞; 获得怀疑是异常血细胞的白细胞分布数据和分配数据; 根据白血细胞的分布数据对白细胞进行计数; 并且根据怀疑是异常血细胞的血细胞的分布数据，确定血液样品中异常血细胞的存在或不存在。 还公开了血液分析方法和计算机程序产品。

    BLOOD ANALYZER, BLOOD ANALYZING METHOD, AND COMPUTER PROGRAM PRODUCT
    4.
    发明申请
    BLOOD ANALYZER, BLOOD ANALYZING METHOD, AND COMPUTER PROGRAM PRODUCT 有权
    血液分析仪，血液分析方法和计算机程序产品

    公开(公告)号：US20100248300A1

    公开(公告)日：2010-09-30

    申请号：US12729989

    申请日：2010-03-23

    申请人： Ayumu Yoshida ,  Shinichiro Oguni ,  Tatsuya Narikawa ,  Saori Suzuki

    发明人： Ayumu Yoshida ,  Shinichiro Oguni ,  Tatsuya Narikawa ,  Saori Suzuki

    IPC分类号： C12Q1/06 ,  C12M1/34

    CPC分类号： G01N15/1459 ,  G01N2015/1006 ,  G01N2015/1402

    摘要： A blood analyzer comprising: a specimen preparation section for preparing a measurement specimen that is used to measure a white blood cell count among CBC measurement items; a measurement section for obtaining optical information from blood cells contained in the measurement specimen; and a controller carrying out operations comprising: classifying blood cells contained in the measurement specimen into at least white blood cells and blood cells suspected to be abnormal blood cells based on the optical information; obtaining distribution data of the white blood cells and distribution data of the blood cells suspected to be abnormal blood cells; counting the white blood cells based on the distribution data of the white blood cells; and determining presence or absence of the abnormal blood cells in the blood sample, based on the distribution data of the blood cells suspected to be abnormal blood cells. A blood analyzing method and a computer program product are also disclosed.

    摘要翻译： 1.一种血液分析装置，其特征在于，具备：准备用于测定CBC测定项目中的白细胞计数的测定试样的检体准备部， 测量部分，用于从测量样本中包含的血球获得光学信息; 以及控制器，其执行操作包括：基于所述光学信息将包含在所述测量样本中的血球细胞分类为怀疑是异常血细胞的至少白血球和血细胞; 获得怀疑是异常血细胞的白细胞分布数据和分配数据; 根据白血细胞的分布数据对白细胞进行计数; 并且根据怀疑是异常血细胞的血细胞的分布数据，确定血液样品中异常血细胞的存在或不存在。 还公开了血液分析方法和计算机程序产品。

    Method and apparatus for measuring hematological sample
    5.
    发明授权
    Method and apparatus for measuring hematological sample 有权
    用于测量血液样品的方法和装置

    公开(公告)号：US07892841B2

    公开(公告)日：2011-02-22

    申请号：US11727806

    申请日：2007-03-28

    申请人： Tomohiro Tsuji ,  Ayumu Yoshida ,  Shinichiro Oguni

    发明人： Tomohiro Tsuji ,  Ayumu Yoshida ,  Shinichiro Oguni

    IPC分类号： G01N33/48 ,  G01N21/47 ,  G01N21/64

    CPC分类号： G01N15/1459 ,  G01N2015/1006 ,  G01N2015/1402 ,  G01N2015/1477 ,  Y10T436/10 ,  Y10T436/101666 ,  Y10T436/25 ,  Y10T436/25125

    摘要： A measuring method and a measuring apparatus which can classify and count myeloblast more precisely without influence of other component in a sample including platelet aggregation in measurement of a blood sample with a flowcytometry, wherein damage is given to a cell membrane of erythrocyte and mature leukocyte contained in a hematological sample, a hemocyte in which a cell membrane is damaged is constricted, and this is dyeing-treated with a fluorescent dye which can stain a nucleic acid to obtain a sample, the sample is measured with a flowcytometer, and a cell contained in a first cell group containing myeloblast, which is specified based on forward scattered light information and side scattered light information, and contained in a second cell group containing myeloblast, which is specified based on forward scattered light information and fluorescent information, is counted as myeloblast.

    摘要翻译： 一种测量方法和测量装置，可以更精确地对成像细胞进行分类和计数，而不影响样品中的其他成分，包括用流式细胞术测量血液样品中的血小板聚集，其中包含红细胞和成熟白细胞的细胞膜受损 在血液样品中，细胞膜损伤的血细胞被收缩，并用荧光染料进行染色处理，荧光染料可以染色核酸以获得样品，用流式细胞仪测量样品，并且含有 在基于前向散射光信息和侧向散射光信息指定的包含成髓细胞的第一细胞组中，包含在基于前向散射光信息和荧光信息指定的含有成髓细胞的第二细胞群中，被计为成髓细胞 。

    Reagent for immature leukocyte analysis and reagent kit
    9.
    发明授权
    Reagent for immature leukocyte analysis and reagent kit 有权
    未成熟白细胞分析试剂和试剂盒

    公开(公告)号：US07625757B2

    公开(公告)日：2009-12-01

    申请号：US11650962

    申请日：2007-01-09

    申请人： Tomohiro Tsuji ,  Ayumu Yoshida ,  Shinichiro Oguni

    发明人： Tomohiro Tsuji ,  Ayumu Yoshida ,  Shinichiro Oguni

    IPC分类号： G01N31/00 ,  G01N33/48

    CPC分类号： G01N33/5094 ,  G01N15/1468 ,  G01N2015/008 ,  Y10T436/10 ,  Y10T436/101666 ,  Y10T436/107497 ,  Y10T436/25125

    摘要： A reagent for analyzing immature leukocyte capable of analyzing accurately immature leukocyte such as myeloblast and immature granulocyte, and mature leukocyte, which reagent has broader allowable range of sample processing conditions than conventional ones, and a reagent kit are provided. The present invention relates to a reagent for analyzing immature leukocyte containing a surfactant for giving damage to cell membrane of red blood cell and mature leukocyte in the sample, a solubilizing agent for causing contraction to damaged blood cell, sugar, a dye for staining nucleic acid.

    摘要翻译： 提供能够分析准确地未成熟白细胞例如成髓细胞和未成熟粒细胞的未成熟白细胞和成熟白细胞的试剂，该试剂比常规试剂处理条件更宽的允许范围和试剂盒。 本发明涉及一种用于分析含有表面活性剂的未成熟白细胞用于对样品中红细胞和成熟白细胞的细胞膜造成损伤的试剂，用于引起血细胞损伤的增溶剂，糖，用于染色核酸的染料 。