摘要:
The present invention provides a process for producing 1,1,1,3,3,3-hexafluoro-2-methoxypropane, wherein a novel compound, 2-methoxy-2-trifluoromethyl-3,3,3-trifluoropropionic acid or a salt thereof is decarboxylated, or wherein an olefin compound represented by chemical formula (4): CF2═C(CF3)(OCH3) is reacted with a fluorinating agent; and a process for producing 2-methoxy-2-trifluoromethyl-3,3,3-trifluoropropionic acid or a salt thereof by reacting a hydroxycarboxylic ester with a methylating agent and then hydrolyzing the reaction product, or hydrolyzing the hydroxycarboxylic ester and then reacting the resulting product with a methylating agent.In accordance with the invention, 1,1,1,3,3,3-hexafluoro-2-methoxypropane, which is useful as a raw material for, for example, the anesthetic Sevoflurane, can be produced efficiently and at low cost.
摘要:
The present invention provides a process for producing 1,1,1,3,3,3-hexafluoro-2-methoxypropane, wherein a novel compound, 2-methoxy-2-trifluoromethyl-3,3,3-trifluoropropionic acid or a salt thereof is decarboxylated, or wherein an olefin compound represented by chemical formula (4): CF2═C(CF3)(OCH3) is reacted with a fluorinating agent; and a process for producing 2-methoxy-2-trifluoromethyl-3,3,3-trifluoropropionic acid or a salt thereof by reacting a hydroxycarboxylic ester with a methylating agent and then hydrolyzing the reaction product, or hydrolyzing the hydroxycarboxylic ester and then reacting the resulting product with a methylating agent.In accordance with the invention, 1,1,1,3,3,3-hexafluoro-2-methoxypropane, which is useful as a raw material for, for example, the anesthetic Sevoflurane, can be produced efficiently and at low cost.
摘要:
The present invention relates to a method for producing a compound represented by formula (2): [CF3(CF2)n][CF3(CF2)m]C(OH)2 (2) wherein n and m independently represent 0 to 10, the method comprising reacting with a halogen or a halogen-containing oxidizing agent a salt of a compound represented by formula (1): [CF3(CF2)n][CF3(CF2)m]C(OH)COOH (1) wherein n and m independently represent 0 to 10.
摘要:
The present invention relates to a method for producing a compound represented by formula (2): [CF3(CF2)n][CF3(CF2)m]C(OH)2 (2) wherein n and m independently represent 0 to 10, the method comprising reacting with a halogen or a halogen-containing oxidizing agent a salt of a compound represented by formula (1): [CF3(CF2)n][CF3(CF2)m]C(OH)COOH (1) wherein n and m independently represent 0 to 10.
摘要:
The present invention provides a process for producing a novel compound, i.e., α-chloromethoxycarboxylic acid ester represented by General Formula (1): (CF3)2C(OCH2Cl)COOR, wherein R is a hydrocarbon group which may be substituted with at least one atom selected from the group consisting of halogen, oxygen, nitrogen, and sulfur atoms, comprising reacting an α-methoxycarboxylic acid ester represented by General Formula (2): (CF3)2C(OCH3)COOR, wherein R is as defined above, with molecular chlorine; and a process for producing 1,1,1,3,3,3-hexafluoroisopropyl fluoromethyl ether represented by a chemical formula (CF3)2CH(OCH2F), comprising fluorinating and decarboxylating the α-chloromethoxycarboxylic acid ester.According to the present invention, 1,1,1,3,3,3-hexafluoroisopropyl fluoromethyl ether (sevoflurane), which is known as a compound having an anesthetic property, can be produced efficiently and at a low cost.
摘要:
The present invention provides a process for producing a novel compound, i.e., α-chloromethoxycarboxylic acid ester represented by General Formula (1): (CF3)2C(OCH2Cl)COOR, wherein R is a hydrocarbon group which may be substituted with at least one atom selected from the group consisting of halogen, oxygen, nitrogen, and sulfur atoms, comprising reacting an α-methoxycarboxylic acid ester represented by General Formula (2): (CF3)2C(OCH3)COOR, wherein R is as defined above, with molecular chlorine; and a process for producing 1,1,1,3,3,3-hexafluoroisopropyl fluoromethyl ether represented by a chemical formula (CF3)2CH(OCH2F), comprising fluorinating and decarboxylating the α-chloromethoxycarboxylic acid ester.According to the present invention, 1,1,1,3,3,3-hexafluoroisopropyl fluoromethyl ether (sevoflurane), which is known as a compound having an anesthetic property, can be produced efficiently and at a low cost.
摘要:
The present invention provides a process for the preparation of hexafluoroacetone characterized by bringing hexafluoro-1,2-epoxypropane into contact with at least one catalyst selected from the group consisting of titanium oxide catalysts and fluorinated titanium oxide catalysts to isomerize hexafluoro-1,2-epoxypropane; and a process for the preparation of hexafluoroacetone hydrate characterized by absorbing the hexafluoroacetone prepared by the above process into water to produce crude hexafluoroacetone hydrate, neutralizing the crude hexafluoroacetone hydrate with an alkali, and distilling the resulting mixture. According to the invention, high-purity hexafluoroacetone can be obtained by isomerization of hexafluoro-1,2-epoxypropane with little formation of by-products, and substantially acid-free high-purity hexafluoroacetone hydrate can also be obtained.
摘要:
An electric automobile includes a fuel cell for power generation by supply of hydrogen and oxidizing agent, a hydrogen generating device for generating a gas containing hydrogen to be supplied to the fuel cell, and a motor driven by electricity generated by the fuel cell. The hydrogen generating device generates gas containing hydrogen by decomposing an organic compound-containing fuel, and includes a proton conductive partition membrane, a fuel electrode provided on one surface of the partition membrane to directly generate the gas containing hydrogen, a device for supplying, to the fuel electrode, water and organic compound-containing fuel capable of producing a proton as a result of electrochemical oxidization which can pass through the partition membrane, an oxidizing electrode provided on the other surface of the partition membrane, a device for supplying the oxidizing agent to the oxidizing electrode, and a device for generating and collecting the gas containing hydrogen.
摘要:
A hydrogen supply system includes at least a hydrogen supply device for supplying hydrogen to a hydrogen storing device, and a hydrogen generating device producing hydrogen containing gas to be supplied to the hydrogen supply device. The hydrogen generating device produces the hydrogen containing gas by decomposing a fuel containing an organic compound, and includes a partition membrane, a fuel electrode provided on one surface of the partition membrane for generating hydrogen containing gas, a device for supplying a fuel containing the organic compound and water to the fuel electrode, an oxidizing electrode provided on the other surface of the partition membrane, a device for supplying an oxidizing agent to the oxidizing electrode, and a device for collecting the hydrogen containing gas directly from the fuel electrode.
摘要:
A hydrogen generating device capable of generating a gas containing hydrogen at a low temperature, as well as a fuel cell power generating device, an electric automobile, a submergible ship and a hydrogen supply system using the hydrogen generating device are provided.A hydrogen generating device (10) for generating a gas containing hydrogen by decomposing a fuel containing an organic compound, includes: a partition membrane (11); a fuel electrode (12) provided on one surface of the partition membrane (11); a means for supplying a fuel containing organic compound and water to the fuel electrode (12); an oxidizing electrode (14) provided on the other surface of the partition membrane (11); a means for supplying an oxidizing agent to the oxidizing electrode (14); and a means for generating and collecting the gas containing hydrogen from the fuel electrode, and a region of insufficient oxidizing agent supply is provided on the oxidizing electrode side so that a reaction (C) 6H++6e−→3H2 may occur on the fuel electrode side and a reaction (D) CH3OH+H2O→6H++6e−+CO2 may occur on the oxidizing electrode side. The region of insufficient oxidizing agent supply can be provided by performing masking (14M) on part of the gas diffusion layer of the oxidizing electrode (14). Moreover, by connecting the hydrogen generating device (10) to a fuel cell and connecting a fuel cell power generating device for supplying a gas containing hydrogen generated by the hydrogen generating device (10) to the fuel cell, an electric automobile and a submergible ship incorporating the fuel cell power generating device, and the hydrogen generating device (10) to a hydrogen storage means, a hydrogen supply system can be configured for supplying a gas containing hydrogen generated by the hydrogen generating device (10) to the hydrogen storage means.