利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

72 条记录 (耗时 0.083 秒)

    Methods and apparatuses for treating gland dysfunction
    1.
    发明授权
    Methods and apparatuses for treating gland dysfunction 有权

    公开(公告)号：US10905898B2

    公开(公告)日：2021-02-02

    申请号：US16375196

    申请日：2019-04-04

    申请人： TearScience, Inc.

    发明人： Stephen M. Grenon ,  Donald R. Korb ,  Timothy R. Willis ,  Benjamin T. Gravely

    IPC分类号： A61N5/06 ,  A61H7/00 ,  A61F9/007 ,  A61N1/40 ,  A61N5/02 ,  A61B18/12 ,  A61B18/04 ,  A61F7/00 ,  A61H15/00 ,  A61N7/00 ,  A61N5/067

    摘要： A method of treating dry eye includes delivering light energy from outside an eyelid toward the eyelid, and maintaining the delivery of the light energy toward the eyelid for a period of time to soften an obstruction of at least one meibomian gland. The light energy may be delivered specifically to the obstruction in the at least one meibomian gland without physically contacting the at least one meibomian gland, or the light energy delivered toward the eyelid may conductively apply heat to the meibomian gland to melt the obstruction. A corresponding apparatus includes a light energy source positionable outside an eyelid and configured to deliver the light energy from outside an eyelid toward the eyelid, and a controller configured to control the light energy source to maintain the delivery of the light energy toward the eyelid for a period of time to soften the obstruction.

    METHODS AND APPARATUSES FOR TREATMENT OF MEIBOMIAN GLANDS
    2.
    发明申请
    METHODS AND APPARATUSES FOR TREATMENT OF MEIBOMIAN GLANDS 审中-公开

    公开(公告)号：US20190282251A1

    公开(公告)日：2019-09-19

    申请号：US16358754

    申请日：2019-03-20

    申请人： TearScience, Inc.

    发明人： Donald R. Korb ,  Timothy R. Willis ,  Stephen M. Grenon

    IPC分类号： A61B17/22 ,  A61F9/007 ,  A61H7/00 ,  A61F7/02

    摘要： Methods and apparatuses of treating meibomian glands are disclosed. An apparatus suitable to treat meibomian glands comprises a heat source, a controller, and a pressure applicator. The heat source is configured to apply regulated heat to an eyelid containing at least one meibomian gland to reach a temperature adequate to melt at least one obstruction within the at least one meibomian gland and place the at least one obstruction in a melted state. The controller is configured to maintain the regulated heat for a time period adequate to melt the at least one obstruction and place the at least one obstruction in the melted state. The pressure applicator is configured to be placed into direct contact with the eyelid and apply a pressure over at least a portion of the eyelid to express the at least one obstruction from the at least one meibomian gland.

    METHODS AND APPARATUSES FOR TREATING GLAND DYSFUNCTION
    3.
    发明申请
    METHODS AND APPARATUSES FOR TREATING GLAND DYSFUNCTION 审中-公开

    公开(公告)号：US20190224497A1

    公开(公告)日：2019-07-25

    申请号：US16375196

    申请日：2019-04-04

    申请人： TearScience, Inc.

    发明人： Stephen M. Grenon ,  Donald R. Korb ,  Timothy R. Willis ,  Benjamin T. Gravely

    IPC分类号： A61N5/06 ,  A61H7/00 ,  A61N1/40 ,  A61N5/02 ,  A61F9/007

    摘要： A method of treating dry eye includes delivering light energy from outside an eyelid toward the eyelid, and maintaining the delivery of the light energy toward the eyelid for a period of time to soften an obstruction of at least one meibomian gland. The light energy may be delivered specifically to the obstruction in the at least one meibomian gland without physically contacting the at least one meibomian gland, or the light energy delivered toward the eyelid may conductively apply heat to the meibomian gland to melt the obstruction. A corresponding apparatus includes a light energy source positionable outside an eyelid and configured to deliver the light energy from outside an eyelid toward the eyelid, and a controller configured to control the light energy source to maintain the delivery of the light energy toward the eyelid for a period of time to soften the obstruction.

    Ocular surface interferometry (OSI) devices and systems for imaging, processing, and/or displaying an ocular tear film
    9.
    发明授权
    Ocular surface interferometry (OSI) devices and systems for imaging, processing, and/or displaying an ocular tear film 有权

    公开(公告)号：US09357915B2

    公开(公告)日：2016-06-07

    申请号：US14299504

    申请日：2014-06-09

    申请人： TearScience Inc.

    发明人： Donald R. Korb ,  William L. Weber ,  Randal B. Chinnock ,  Benjamin T. Gravely ,  Stephen M. Grenon

    IPC分类号： A61B3/14 ,  A61B3/10 ,  A61B3/02 ,  A61B5/05 ,  A61B3/00 ,  G06T7/00

    摘要： Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).

    Apparatuses and methods of ocular surface interferometry (OSI) employing polarization and subtraction for imaging, processing, and/or displaying an ocular tear film
    10.
    发明授权
    Apparatuses and methods of ocular surface interferometry (OSI) employing polarization and subtraction for imaging, processing, and/or displaying an ocular tear film 有权
    使用偏振和减光进行成像，处理和/或显示眼泪膜的眼表干涉测量（OSI）的装置和方法

    公开(公告)号：US08915592B2

    公开(公告)日：2014-12-23

    申请号：US13870054

    申请日：2013-04-25

    申请人： TearScience, Inc.

    发明人： Donald R. Korb ,  William L. Weber ,  Randal B. Chinnock ,  Benjamin T. Gravely ,  Stephen M. Grenon

    IPC分类号： A61B3/14 ,  A61B3/10 ,  A61B3/02 ,  A61B5/05 ,  A61B3/00 ,  G06T7/00 ,  G01B11/06 ,  G06T5/00 ,  G06T5/50

    CPC分类号： A61B3/101 ,  A61B3/0025 ,  G01B11/0675 ,  G06T5/002 ,  G06T5/50 ,  G06T7/0012 ,  G06T2207/10016 ,  G06T2207/20224 ,  G06T2207/30041

    摘要： Apparatuses and methods employing ocular surface interferometry (OSI) employing polarization and subtraction for imaging, processing, and/or displaying an ocular tear film are disclosed. The apparatuses and methods can be employed for measuring tear film layer thickness (TFLT) of the ocular tear film, which includes lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). An imaging device is focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device is focused on the lipid layer of the tear film to capture a second image containing background signal(s) in the first image. The second image can be subtracted from the first image to reduce and/or eliminate background signal(s) in the first image to produce a resulting image that can be analyzed to measure tear film layer thickness (TFLT).

    摘要翻译： 公开了使用用于成像，处理和/或显示眼泪膜的偏振和减影的眼表面干涉测量（OSI）的装置和方法。 该装置和方法可用于测量眼泪膜的泪膜层厚度（TFLT），其包括脂质层厚度（LLT）和/或水层厚度（ALT）。 成像装置集中在泪膜的脂质层上，以捕获与第一图像中的背景信号结合的来自泪膜的镜面反射光的光波干涉相互作用。 成像装置聚焦在泪膜的脂质层上，以捕获包含第一图像中的背景信号的第二图像。 可以从第一图像中减去第二图像以减少和/或消除第一图像中的背景信号，以产生可以被分析以测量泪膜层厚度（TFLT）的所得图像。