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    Naphthyridine derivatives having inhibitory activity against hiv integrase
    1.
    发明申请
    Naphthyridine derivatives having inhibitory activity against hiv integrase 有权
    对hiv整合酶具有抑制活性的萘啶衍生物

    公开(公告)号：US20090227621A1

    公开(公告)日：2009-09-10

    申请号：US10587857

    申请日：2005-02-02

    申请人： Teruhiko Taishi ,  Yukio Tada

    发明人： Teruhiko Taishi ,  Yukio Tada

    IPC分类号： A61K31/4375 ,  C07D471/02 ,  A61P31/18

    CPC分类号： C07D471/04

    摘要： [Problems to be Solved] To provide a novel compound having antiviral activity, especially inhibitory activity against HIV integrase, a pharmaceutical composition, especially anti-HIV drug, containing the same. [Means to Solve the Problem] A compound of the formula: (wherein: R1 is optionally substituted aralkyl; R2 and R3 are each independently hydrogen, optionally substituted alkyl, optionally substituted amino, optionally substituted alkenyl or optionally substituted alkoxy (provided that each substituent for “optionally substituted” is a noncyclic group); R4 is hydrogen, optionally substituted carboxy, optionally substituted formylamino, optionally substituted carbamoyl, optionally substituted amino (provided that a substituent on amino in “optionally substituted formylamino”, “optionally substituted carbamoyl” and “optionally substituted amino” may form an optionally-substituted N-atom containing heterocyclic ring together with an adjacent N atom), optionally substituted alkyl, optionally substituted alkenyl, optionally substituted aryl, or optionally substituted heteroaryl) or a salt thereof.

    摘要翻译： [待解决的问题]提供具有抗病毒活性，特别是针对HIV整合酶的抑制活性的新型化合物，含有该化合物的药物组合物，特别是抗HIV药物。 解决问题的方法下式化合物：其中：R 1为任选取代的芳烷基; R 2和R 3各自独立地为氢，任选取代的烷基，任选取代的氨基，任选取代的烯基或任选取代的烷氧基（条件是每个取代基 对于“任选取代的”是非环基团）; R 4是氢，任选取代的羧基，任选取代的甲酰氨基，任选取代的氨基甲酰基，任选取代的氨基（条件是“任选取代的甲酰氨基” “任选取代的氨基”可以与相邻的N原子一起形成任选取代的含有N原子的杂环，任选取代的烷基，任选取代的烯基，任选取代的芳基或任选取代的杂芳基）或其盐。

    Naphthyridine derivatives having inhibitory activity against HIV integrase
    2.
    发明授权
    Naphthyridine derivatives having inhibitory activity against HIV integrase 有权
    对HIV整合酶具有抑制活性的萘吡啶衍生物

    公开(公告)号：US07919623B2

    公开(公告)日：2011-04-05

    申请号：US10587857

    申请日：2005-02-02

    申请人： Teruhiko Taishi ,  Yukio Tada

    发明人： Teruhiko Taishi ,  Yukio Tada

    IPC分类号： C07D471/02

    CPC分类号： C07D471/04

    摘要： A compound having HIV Integrase Inhibitory activity of the formula: (wherein: R1 is optionally substituted aralkyl; R2 and R3 are each independently hydrogen, optionally substituted alkyl, optionally substituted amino, optionally substituted alkenyl or optionally substituted alkoxy (provided that each substituent for “optionally substituted” is a noncyclic group); R4 is hydrogen, optionally substituted carboxy, optionally substituted formylamino, optionally substituted carbamoyl, optionally substituted amino (provided that a substituent on amino in “optionally substituted formylamino”, “optionally substituted carbamoyl” and “optionally substituted amino” may form an optionally-substituted N-atom containing heterocyclic ring together with an adjacent N atom), optionally substituted alkyl, optionally substituted alkenyl, optionally substituted aryl, or optionally substituted heteroaryl) or a salt thereof.

    摘要翻译： 具有下式的HIV整合酶抑制活性的化合物：其中：R 1为任选取代的芳烷基; R 2和R 3各自独立地为氢，任选取代的烷基，任选取代的氨基，任选取代的烯基或任选取代的烷氧基（条件是每个取代基为“ 任选取代的“是非环基团）; R 4是氢，任选取代的羧基，任选取代的甲酰氨基，任选取代的氨基甲酰基，任选取代的氨基（条件是在”任选取代的甲酰氨基“中的氨基上的取代基，”任选取代的氨基甲酰基“ 取代的氨基“可以与相邻的N原子一起形成任选取代的含有N原子的杂环，任选取代的烷基，任选取代的烯基，任选取代的芳基或任选取代的杂芳基）或其盐。

    Echo removing apparatus
    3.
    发明授权
    Echo removing apparatus 有权
    回波消除装置

    公开(公告)号：US08630405B2

    公开(公告)日：2014-01-14

    申请号：US12677200

    申请日：2008-09-24

    申请人： Yukio Tada

    发明人： Yukio Tada

    IPC分类号： H04M1/00 ,  H04M9/00 ,  H04M9/08

    CPC分类号： H04M9/082 ,  H01L2924/14 ,  H01L2924/00

    摘要： An echo removing apparatus that can remove an echo appropriately if the produced sound volume becomes large although the configuration is simple is provided. A control section 17 switches the operations of an echo suppressor 14 and an echo canceller 15 in response to the volume value input from a volume operation section 18. If the volume value is large, the echo suppressor 14 is operated and an echo is suppressed reliably. If the volume value is small, the echo canceller 15 is operated and double talk is enabled.

    摘要翻译： 如果产生的音量变大，则尽管配置简单，但是可以适当地去除回声的回波消除装置。 控制部分17响应于从音量操作部分18输入的音量值来切换回波抑制器14和回波消除器15的操作。如果音量值大，则回波抑制器14被操作并且可靠地抑制回波 。 如果音量值较小，则回波消除器15被操作，并且启用双方通话。

    Music session support method, musical instrument for music session, and music session support program
    5.
    发明申请
    Music session support method, musical instrument for music session, and music session support program 有权
    音乐会议支持方式，音乐会乐器和音乐会议支持节目

    公开(公告)号：US20050120865A1

    公开(公告)日：2005-06-09

    申请号：US11002427

    申请日：2004-12-02

    申请人： Yukio Tada

    发明人： Yukio Tada

    IPC分类号： G06F15/00 ,  G10H1/00 ,  A63F9/24 ,  A63F13/00 ,  G06F17/00 ,  G06F19/00

    CPC分类号： G10H1/0058

    摘要： A music session support method which enables each of players in a music session which is performed via a network to immediately recognize whether or not the other players are in the state of being able to participate in the session. A session support apparatus 10 transmits sets of status information indicative of whether or not each of players is in a state of being able to participate in a session, and player identification information which identifies the players, to each of session terminals 20. Each of the session terminals 20 which have received the sets of status information and player identification information causes a touch display 24 thereof to display the status information for each of the players. The session support apparatus 10 acquires a set of status transition information indicating that a player of at least one of the session terminals 20 in which the detecting device has detected the performance preparatory operation has gone into the state of being able to participate in a session, and player identification information for a session terminal 20, from the session terminal 20. The session support apparatus 10 transmits the acquired set of status transition information and player identification information to the session terminals 20. Each of the session terminals 20 updates contents displayed on the touch display 24 thereof, based upon the status transition information and player identification information transmitted from the session support apparatus 10.

    摘要翻译： 一种音乐会话支持方法，其使得经由网络执行的音乐会话中的每个玩家能够立即识别其他玩家是否处于能够参与该会话的状态。 会话支持装置10发送指示每个玩家是否处于能够参加会话的状态的状态信息集合以及识别玩家的玩家识别信息给每个会话终端20.每个 已经接收到状态信息和玩家识别信息的会话终端20使其触摸显示器24显示每个玩家的状态信息。 会话支持装置10获取指示检测装置已经检测到演奏预备操作的会话终端20中的至少一个已经进入能够参加会话的状态的一组状态转换信息， 以及来自会话终端20的会话终端20的播放器识别信息。会话支持装置10将获取的一组状态转换信息和玩家识别信息发送到会话终端20.每个会话终端20更新显示在 基于从会话支持装置10发送的状态转移信息和玩家识别信息，触摸显示器24。

    Internal combustion engine
    7.
    发明授权
    Internal combustion engine 失效
    内燃机

    公开(公告)号：US4570587A

    公开(公告)日：1986-02-18

    申请号：US594162

    申请日：1984-03-28

    申请人： Yoshimi Watanabe ,  Yukio Tada ,  Takanori Suzuki ,  Hitoshi Suzuki

    发明人： Yoshimi Watanabe ,  Yukio Tada ,  Takanori Suzuki ,  Hitoshi Suzuki

    IPC分类号： F02B61/00 ,  F02B63/02 ,  F02B75/00 ,  F02B75/02 ,  F02B75/16 ,  F02F7/00 ,  F01B31/00

    CPC分类号： F02B75/007 ,  F02B61/00 ,  F02B63/02 ,  F02B75/16 ,  F02F7/00 ,  F02B2075/027 ,  F02B2275/34 ,  Y10S123/06

    摘要： An internal combustion engine includes a crank shaft having a crank web, a crank pin on one end of the crank web, and a weight on an opposite end of the crank web, a crank case supporting the crank shaft therein, a cylinder, a piston reciprocally fitted in the cylinder, a rod coupled to the piston by a piston pin and connecting the piston to the crank pin for reciprocally moving the piston in the cylinder, the crank case having an opening and extending obliquely to axes of the crank shaft and the cylinder. The cylinder has an end corresponding to a bottom dead center of the piston and having a first recess opening toward the opening, the first recess being of a size allowing the piston pin to pass therethrough when the piston is in the bottom dead center. The weight on the crank web has on one side a second recess of a shape defining with the end of the cylinder a space allowing the piston as disconnected from the rod to pass therethrough.

    摘要翻译： 一种内燃机，其特征在于，具备曲柄轴，曲柄腹板一端的曲柄销，曲柄腹板的另一端的曲柄轴，支承曲轴的曲轴箱，缸体，活塞 往复安装在气缸中，杆通过活塞销连接到活塞，并将活塞连接到曲柄销，以使活塞在气缸中往复运动，曲轴箱具有开口并且倾斜地延伸到曲轴的轴线和 圆筒。 气缸具有对应于活塞的下死点的端部，并且具有朝向开口的第一凹部开口，当活塞处于下止点时，第一凹部具有允许活塞销穿过的尺寸。 曲柄腹板上的重量在一侧具有形状为圆柱体端部的形状的第二凹槽，允许活塞与杆分离的空间通过。