摘要:
A random copolyester is described, comprising recurring moieties represented by formula (I), (II), and (III), and having an intrinsic viscosity of not less than 0.5, wherein said recurring moieties of formulae (I) and (II) are existing substantially in equimolar amount and recurring moieties of formulae (I) and (III) are present in a molar ratio of from 95/5 to 5/95 ##STR1## wherein Ar.sub.1 represents a trivalent aromatic group and Ar.sub.2 represents a divalent aromatic group. In formulae (I), (II), and (III), aromatic rings may be substituted with an alkyl group or an alkoxy group having from 1 to 20 carbon atoms, an aryl group or aryloxy group having from 6 to 20 carbon atoms, or a halogen atom. The copolyester obtained is excellent in heat resistance and flame retardance.
摘要:
A flame resistant polyester produced by addition and copolymerization of a phosphorus compound represented by general formula (I) below as a diol component of the polyester in an amount of 500 ppm or more in terms of phosphorus atom content in the polyester, which polyester has alkylene terephthalate units as main repeating units and which has an intrinsic viscosity of not less than 0.5 measured at 20.degree. C. in a mixture of equal weight of phenol and tetrachloroethane: ##STR1## where E is --CH.sub.2 CH.sub.2 --, Ar is an aromatic group or an aromatic group substituted by a lower alkyl group or a halogen atom, and m and n denote, respectively, integers the sum of which is from 1 to 20.
摘要:
A polyester, wherein pendent phosphorus atoms are bound to the main chain of the polyester, having an excellent flame resistance and a high intrinsic viscosity can be stably produced without deteriorating the properties of said polyester by preliminarily copolymerizing a polyester with a specific unsaturated compound and then reacting the unsaturated bond thus-formed with a specific phosphorus compound having a P-H bond.
摘要:
A safe and effective hemostatic is provided. The invention relates to a bioabsorbable synthetic nonwoven fabric holding thrombin as an effective ingredient and a hemostatic comprising said bioabsorbable synthetic nonwoven fabric. The bioabsorbable synthetic nonwoven fabric holding thrombin in accordance with the present invention may be prepared by a process which comprises the steps of immersing a bioabsorbable synthetic nonwoven fabric into a solution containing thrombin and of lyophilizing the obtained nonwoven fabric. The bioabsorbable synthetic nonwoven fabric holding thrombin in accordance with the present invention allows for quicker and more effective hemostasis.
摘要:
A recombinant ecarin protein that specifically activates prothrombin, said protein being efficiently prepared by the genetic engineering technique comprising the steps: (1) culturing a transformant microorganism or animal cell transformed with an expression vector in which a gene encoding ecarin is incorporated to the downstream of a promoter so as to produce and accumulate ecarin in culture supernatant or within said transformant and recovering the produced ecarin; and (2) purifying a solution containing the recovered ecarin to obtain purified ecarin. The present invention allows for production of recombinant ecarin on an industrial scale.
摘要:
An input disk, a clutch disk and wave washers are installed to an output shaft to form an output shaft assembly of a motor apparatus. The input disk is axially non-detachable from the output shaft and is rotatable about an axis of the output shaft. The input disk is driven by a drive force supplied from a motor main body of the motor apparatus. The clutch disk is supported by the output shaft in such a manner that the clutch disk is non-rotatable relative to the output shaft and is axially movable along the output shaft relative to the input disk. The wave washers apply a resistive force against axial movement of the clutch disk from a coupled state, at which the input disk is coupled with the clutch disk to rotate together.
摘要:
An input disk, a clutch disk and wave washers are installed to an output shaft to form an output shaft assembly of a motor apparatus. The input disk is axially non-detachable from the output shaft and is rotatable about an axis of the output shaft. The input disk is driven by a drive force supplied from a motor main body of the motor apparatus. The clutch disk is supported by the output shaft in such a manner that the clutch disk is non-rotatable relative to the output shaft and is axially movable along the output shaft relative to the input disk. The wave washers apply a resistive force against axial movement of the clutch disk from a coupled state, at which the input disk is coupled with the clutch disk to rotate together.
摘要:
The present invention relates to a tissue sealant which is safe and effective. In accordance with the present invention, a tissue sealant comprising as an effective ingredient thrombin and fibrinogen characterized in that a bioabsorbable synthetic nonwoven fabric is used as a supporting material; use of a combination of a bioabsorbable synthetic nonwoven fabric as a supporting material and thrombin and fibrinogen as an effective ingredient for a tissue sealant; use of a combination of a bioabsorbable synthetic nonwoven fabric holding thrombin as an effective ingredient, and fibrinogen as an effective ingredient for a tissue sealant; a tissue sealing kit comprising a bioabsorbable synthetic nonwoven fabric holding thrombin as an effective ingredient, and a container comprising fibrinogen as an effective ingredient; and a tissue sealing kit comprising a bioabsorbable synthetic nonwoven fabric as a substrate, a container comprising thrombin as an effective ingredient and a container comprising fibrinogen as an effective ingredient are provided.
摘要:
The present invention provides a hemostatic material which is excellent in hemostatic property, biodegradability and bioabsorbability, uniformity and stability of the quality, as well as reduces a risk of contamination with a pathogenic organism derived from an animal. The hemostatic material comprises a thrombin and a synthetic polypeptide capable of forming a triple helical structure. The polypeptide may show a peak of the molecular weight in the range from 5×104 to 100×104 in the molecular weight distribution. The polypeptide may contain at least a peptide unit represented by the formula: -Pro-X-Gly- (in the formula, X represents Pro or Hyp). The thrombin may be a recombinant. In the hemostatic material, the proportion of the thrombin may be about 0.1 to 500 units (U) relative to 1 mg of the polypeptide. The hemostatic material may further comprise a binder component having biodegradability and bioabsorbability. The hemostatic material may be formed on a substrate.
摘要:
A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.