摘要:
Citalopram can be industrially and economically produced and at a high yield by reacting a compound of the following formula [VI] with 3-(dimethylamino)propyl chloride in the presence of at least one of N,N,N′,N′-tetramethylethylenediamine and 1,3-dimethyl-2-imidazolidinone and a condensing agent.
摘要:
Citalopram can be industrially and economically produced and at a high yield by reacting a compound of the following formula [VI] with 3-(dimethylamino)propyl chloride in the presence of at least one of N,N,N′,N′-tetramethylethylenediamine and 1,3-dimethyl-2-imidazolidinone and a condensing agent. The compound of the following formula [III], which is a key compound for the production of citalopram, can be easily produced by subjecting the compound of the following formula [II] to reduction and cyclization.
摘要:
According to the present invention, citalopram hydrobromide dissolved in a solvent containing at least one member selected from the group consisting of alcohol having 1-3 carbon atoms, water and acetone is crystallized or recrystallized while controlling the cooling rate, thereby to 1) provide an industrial method for crystallizing citalopram hydrobromide, which enables easy control of the crystal characteristics, such as particle size, particle size distribution and aspect ratio and the like of the crystal, and 2) provide citalopram hydrobromide crystal having crystal characteristics useful as a pharmaceutical bulk.
摘要:
An epoxy compound of the formula (1): wherein, R represents a hydrogen atom or an alkyl group having 1 to 12 carbon atoms, and Ar represents an optionally substituted aromatic group, can be purified by dissolving a crude product containing the epoxy compound (1), an aprotic polar solvent and an alkali metal salt in a two-phase solvent composed of water and an organic solvent, which is capable of phase-separating from water, obtaining the organic layer by phase separation, washing with water and then subjecting to isolation of the epoxy compound (1) without decomposition.
摘要:
The present invention provides a process for recovering 1,3-dimethyl-2-imidazolidinone comprising extracting 1,3-dimethyl-2-imidazolidinone from an aqueous solution containing it with n-butanol in the presence of an inorganic salt to obtain n-butanol layer and, subjecting the n-butanol layer to distillation. As 1,3-dimethyl-2-imidazolidinone can be recoverable at high purity from an aqueous solution containing 1,3-dimethyl-2-imidazolidinone easily and efficiently without using alkali, the present process is industrially advantageous.
摘要:
There is provided a surface light source device of side light type, which is not reduced in efficiency of illumination light utilization, even if the surface light source device is subjected to fringing such as to trim a luminant portion. For instance, a light shielding layer formed by coating black ink 21A, which absorbs illumination light, by means of printing is provided on a protection sheet 21 arranged as the outermost emission-side additional sheet. The light shielding layer absorbs and shields illumination light L1 tending to be transmitted through a peripheral edge portion of the protection sheet 12, and as a result, provides fringing. A reflective surface is formed by applying a silver tape 21B or the like to a surface facing the light guide plate 6. Since illumination light reflected by the silver tape 21B is used again inside the light guide plate 6, it is possible to avoid a reduction in efficiency of light utilization. The reflective layer may be narrower or wider than the light shielding layer, or may be equal in width to the light shielding layer at need. The reflective surface and the light shielding layer may be also formed on other components.
摘要:
There is offered a battery charger for a portable electronic device that has a simple structure and is capable of detecting that the portable electronic device is connected to the battery charger. A first power supply line is connected to a positive terminal (+) of a rechargeable battery, while a ground line is connected to a negative terminal (−) of the rechargeable battery. An output transistor is connected between the first power supply line and a second power supply line. The output transistor is connected to a Vbus terminal of a USB connector through the second power supply line. A controller outputs a voltage of an H level to the Vbus terminal to detect a change in a voltage at the Vbus terminal, and judges whether the portable electronic device is connected to the USB connector based on a result of the detection. The controller turns the output transistor on when the portable electronic device is judged to be connected to the USB connector.
摘要:
Objects of the present invention are to provide an endless metal belt superior in flexing resistance and durability, to provide a fixing belt using the endless metal belt, and to provide a heat fixing device with high durability and high reliability. The objects are achieved by the endless metal belt formed of a nickel alloy containing 5% by weight or more of an additional metallic element and having a half-value width of an X-ray diffraction peak in a range of 0.5 degrees to 2 degrees for each of a crystal plane and a crystal plane, and by using the same.
摘要:
Signal lines and ground lines formed on a major surface of a printed circuit board are electrically connected to signal lines and ground lines on a major surface of a flexible printed circuit film opposed to the major surface of the printed circuit board through a stacking connector, a conductive coupling member and another conductive coupling member are attached to a first ground pattern formed on the major surface of the printed circuit board and a second ground pattern formed on the reverse surface of the flexible printed circuit film, and the conductive coupling members are engaged with each other so as to provide a bypass of the conductive paths in the stacking connector for the ground lines and a shield against electro-magnetic noise radiated from the stacking connector.
摘要:
A charger includes a power supply generating a direct current power supply potential, an output transistor, a USB connector, a controller, and a resistor bridge circuit. The controller has a potential setting circuit which sets the potentials of the first and second connection nodes of the resistor bridge circuit to a middle potential between a power supply potential and a ground potential in a first mode, and sets the potentials of the first and second connection nodes to the power supply potential in a second mode.