Production method of citalopram, intermediate therefor and production method of the intermediate
    2.
    发明授权
    Production method of citalopram, intermediate therefor and production method of the intermediate 失效
    西酞普兰的生产方法,中间体和中间体的生产方法

    公开(公告)号:US06433196B1

    公开(公告)日:2002-08-13

    申请号:US09654768

    申请日:2000-09-05

    IPC分类号: C07D30778

    摘要: Citalopram can be industrially and economically produced and at a high yield by reacting a compound of the following formula [VI] with 3-(dimethylamino)propyl chloride in the presence of at least one of N,N,N′,N′-tetramethylethylenediamine and 1,3-dimethyl-2-imidazolidinone and a condensing agent. The compound of the following formula [III], which is a key compound for the production of citalopram, can be easily produced by subjecting the compound of the following formula [II] to reduction and cyclization.

    摘要翻译: 通过在N,N,N',N'-四甲基乙二胺中的至少一种的存在下使下式[Ⅵ]化合物与3-(二甲基氨基)丙基氯反应,可以工业和经济地制备,并以高收率 和1,3-二甲基-2-咪唑啉酮和缩合剂。 通过使下式[Ⅱ]的化合物还原和环化,可以容易地制备作为西酞普兰生产的关键化合物的下式[III]的化合物。

    Citalopram hydrobromide crystal and method for crystallization thereof
    3.
    发明授权
    Citalopram hydrobromide crystal and method for crystallization thereof 失效
    西酞普兰氢溴酸盐晶体及其结晶方法

    公开(公告)号:US06977306B2

    公开(公告)日:2005-12-20

    申请号:US09824447

    申请日:2001-04-02

    CPC分类号: C07D307/87

    摘要: According to the present invention, citalopram hydrobromide dissolved in a solvent containing at least one member selected from the group consisting of alcohol having 1-3 carbon atoms, water and acetone is crystallized or recrystallized while controlling the cooling rate, thereby to 1) provide an industrial method for crystallizing citalopram hydrobromide, which enables easy control of the crystal characteristics, such as particle size, particle size distribution and aspect ratio and the like of the crystal, and 2) provide citalopram hydrobromide crystal having crystal characteristics useful as a pharmaceutical bulk.

    摘要翻译: 根据本发明,在控制冷却速度的同时,溶解在含有选自具有1-3个碳原子的醇中的至少一种的水溶液和水和丙酮中​​的西酞普兰氢溴酸盐结晶或重结晶,从而1) 用于结晶西酞普兰氢溴酸盐的工业方法,其能够容易地控制晶体的晶体特性,例如粒度,粒度分布和长宽比等,以及2)提供具有作为药物体积有用的晶体特性的西酞普兰氢溴酸盐晶体。

    Method of purifying epoxy compound
    4.
    发明申请
    Method of purifying epoxy compound 失效
    环氧化合物的净化方法

    公开(公告)号:US20080081921A1

    公开(公告)日:2008-04-03

    申请号:US11889524

    申请日:2007-08-14

    IPC分类号: C07D303/12

    CPC分类号: C07D301/32 C07D303/08

    摘要: An epoxy compound of the formula (1): wherein, R represents a hydrogen atom or an alkyl group having 1 to 12 carbon atoms, and Ar represents an optionally substituted aromatic group, can be purified by dissolving a crude product containing the epoxy compound (1), an aprotic polar solvent and an alkali metal salt in a two-phase solvent composed of water and an organic solvent, which is capable of phase-separating from water, obtaining the organic layer by phase separation, washing with water and then subjecting to isolation of the epoxy compound (1) without decomposition.

    摘要翻译: 式(1)的环氧化合物:其中,R表示氢原子或碳原子数1〜12的烷基,Ar表示可以具有取代基的芳香族基,可以将含有环氧化合物的粗制品 1),非质子极性溶剂和碱金属盐在由水和有机溶剂组成的两相溶剂中,其能够与水相分离,通过相分离获得有机层,用水洗涤,然后 以分解环氧化合物(1)而不分解。

    Process for recovering 1,3-dimethyl-2-imidazolidinone
    5.
    发明申请
    Process for recovering 1,3-dimethyl-2-imidazolidinone 失效
    回收1,3-二甲基-2-咪唑烷酮的方法

    公开(公告)号:US20050261505A1

    公开(公告)日:2005-11-24

    申请号:US11129357

    申请日:2005-05-16

    CPC分类号: C07D233/32

    摘要: The present invention provides a process for recovering 1,3-dimethyl-2-imidazolidinone comprising extracting 1,3-dimethyl-2-imidazolidinone from an aqueous solution containing it with n-butanol in the presence of an inorganic salt to obtain n-butanol layer and, subjecting the n-butanol layer to distillation. As 1,3-dimethyl-2-imidazolidinone can be recoverable at high purity from an aqueous solution containing 1,3-dimethyl-2-imidazolidinone easily and efficiently without using alkali, the present process is industrially advantageous.

    摘要翻译: 本发明提供一种回收1,3-二甲基-2-咪唑啉酮的方法,其包括在无机盐存在下,从含有正丁醇的水溶液中提取1,3-二甲基-2-咪唑啉酮,得到正丁醇 层,并使正丁醇层进行蒸馏。 由于1,3-二甲基-2-咪唑啉酮可以在不使用碱的情况下容易且有效地从含有1,3-二甲基-2-咪唑啉酮的水溶液中以高纯度回收,因此本工艺在工业上是有利的。

    Surface light source device having shielding layer
    6.
    发明授权
    Surface light source device having shielding layer 失效
    表面光源装置,其具有屏蔽层片材和在导光层之间的反射层

    公开(公告)号:US6079840A

    公开(公告)日:2000-06-27

    申请号:US953553

    申请日:1997-10-17

    CPC分类号: G02B6/0055

    摘要: There is provided a surface light source device of side light type, which is not reduced in efficiency of illumination light utilization, even if the surface light source device is subjected to fringing such as to trim a luminant portion. For instance, a light shielding layer formed by coating black ink 21A, which absorbs illumination light, by means of printing is provided on a protection sheet 21 arranged as the outermost emission-side additional sheet. The light shielding layer absorbs and shields illumination light L1 tending to be transmitted through a peripheral edge portion of the protection sheet 12, and as a result, provides fringing. A reflective surface is formed by applying a silver tape 21B or the like to a surface facing the light guide plate 6. Since illumination light reflected by the silver tape 21B is used again inside the light guide plate 6, it is possible to avoid a reduction in efficiency of light utilization. The reflective layer may be narrower or wider than the light shielding layer, or may be equal in width to the light shielding layer at need. The reflective surface and the light shielding layer may be also formed on other components.

    摘要翻译: 提供了一种侧光型的面光源装置,即使表面光源装置受到诸如修整发光体部分的边缘的影响,也不会降低照明光利用的效率。 例如,在作为最外侧发光侧附加片配置的保护片21上设置通过涂布通过印刷吸收照明光的黑色墨21A形成的遮光层。 遮光层吸收并遮蔽趋向于透过保护片12的周边部分的照明光L1,结果提供了边缘。 通过将银带21B等施加到与导光板6相对的表面来形成反射表面。由于在导光板6内再次使用由银带21B反射的照明光,因此可以避免减少 在光利用效率上。 反射层可以比遮光层更窄或更宽,或者在需要时可以与遮光层的宽度相等。 反射表面和遮光层也可以形成在其它部件上。

    Battery charger for portable electronic equipment
    7.
    发明授权
    Battery charger for portable electronic equipment 有权
    便携式电子设备电池充电器

    公开(公告)号:US09142985B2

    公开(公告)日:2015-09-22

    申请号:US13078384

    申请日:2011-04-01

    摘要: There is offered a battery charger for a portable electronic device that has a simple structure and is capable of detecting that the portable electronic device is connected to the battery charger. A first power supply line is connected to a positive terminal (+) of a rechargeable battery, while a ground line is connected to a negative terminal (−) of the rechargeable battery. An output transistor is connected between the first power supply line and a second power supply line. The output transistor is connected to a Vbus terminal of a USB connector through the second power supply line. A controller outputs a voltage of an H level to the Vbus terminal to detect a change in a voltage at the Vbus terminal, and judges whether the portable electronic device is connected to the USB connector based on a result of the detection. The controller turns the output transistor on when the portable electronic device is judged to be connected to the USB connector.

    摘要翻译: 为便携式电子设备提供电池充电器,其具有简单的结构并且能够检测便携式电子设备连接到电池充电器。 第一电源线连接到可充电电池的正极(+),而地线连接到可再充电电池的负极( - )。 输出晶体管连接在第一电源线和第二电源线之间。 输出晶体管通过第二电源线连接到USB连接器的Vbus端子。 控制器向Vbus终端输出H电平,以检测Vbus终端的电压变化,并且基于检测结果来判断便携式电子设备是否连接到USB连接器。 当便携式电子设备被判断为连接到USB连接器时,控制器接通输出晶体管。

    ENDLESS METAL BELT, FIXING BELT AND HEAT FIXING DEVICE
    8.
    发明申请
    ENDLESS METAL BELT, FIXING BELT AND HEAT FIXING DEVICE 审中-公开
    无铅金属带,固定带和热固定装置

    公开(公告)号:US20070147915A1

    公开(公告)日:2007-06-28

    申请号:US11681547

    申请日:2007-03-02

    IPC分类号: G03G15/20

    摘要: Objects of the present invention are to provide an endless metal belt superior in flexing resistance and durability, to provide a fixing belt using the endless metal belt, and to provide a heat fixing device with high durability and high reliability. The objects are achieved by the endless metal belt formed of a nickel alloy containing 5% by weight or more of an additional metallic element and having a half-value width of an X-ray diffraction peak in a range of 0.5 degrees to 2 degrees for each of a crystal plane and a crystal plane, and by using the same.

    摘要翻译: 本发明的目的是提供一种抗弯曲性和耐久性优异的环形金属带,提供使用该环形金属带的定影带,并且提供具有高耐久性和高可靠性的热定影装置。 目的是通过由含有5重量%以上的附加金属元素的镍合金形成的无端金属带实现的,并且在0.5度-2度的范围内具有0.5度至2度的X射线衍射峰的半值宽度, 每个晶体平面和晶体平面,并使用它们。

    Structure of printed circuit boards coupled through stacking connectors
    9.
    发明授权
    Structure of printed circuit boards coupled through stacking connectors 失效
    通过堆叠连接器耦合的印刷电路板的结构

    公开(公告)号:US5967799A

    公开(公告)日:1999-10-19

    申请号:US928511

    申请日:1997-09-12

    申请人: Nobuhiro Arai

    发明人: Nobuhiro Arai

    CPC分类号: H01R23/662 H01R12/79

    摘要: Signal lines and ground lines formed on a major surface of a printed circuit board are electrically connected to signal lines and ground lines on a major surface of a flexible printed circuit film opposed to the major surface of the printed circuit board through a stacking connector, a conductive coupling member and another conductive coupling member are attached to a first ground pattern formed on the major surface of the printed circuit board and a second ground pattern formed on the reverse surface of the flexible printed circuit film, and the conductive coupling members are engaged with each other so as to provide a bypass of the conductive paths in the stacking connector for the ground lines and a shield against electro-magnetic noise radiated from the stacking connector.

    摘要翻译: 形成在印刷电路板的主表面上的信号线和接地线通过堆叠连接器电连接到与印刷电路板的主表面相对的柔性印刷电路膜的主表面上的信号线和接地线, 导电耦合构件和另一个导电耦合构件附接到形成在印刷电路板的主表面上的第一接地图案​​和形成在柔性印刷电路膜的反面上的第二接地图案,并且导电耦合构件与 彼此提供用于接地线的堆叠连接器中的导电路径的旁路,以及防止从堆叠连接器辐射的电磁噪声的屏蔽。

    Charger for portable electronic device
    10.
    发明授权
    Charger for portable electronic device 有权
    便携式电子设备充电器

    公开(公告)号:US08907634B2

    公开(公告)日:2014-12-09

    申请号:US13416890

    申请日:2012-03-09

    IPC分类号: H02J7/00 H02J7/04

    CPC分类号: H02J7/04

    摘要: A charger includes a power supply generating a direct current power supply potential, an output transistor, a USB connector, a controller, and a resistor bridge circuit. The controller has a potential setting circuit which sets the potentials of the first and second connection nodes of the resistor bridge circuit to a middle potential between a power supply potential and a ground potential in a first mode, and sets the potentials of the first and second connection nodes to the power supply potential in a second mode.

    摘要翻译: 充电器包括产生直流电源电位的电源,输出晶体管,USB连接器,控制器和电阻桥电路。 控制器具有电位设定电路,其将第一模式中的电阻电桥电路的第一和第二连接节点的电位设定为电源电位与接地电位之间的中间电位,并设定第一和第二电位的电位 连接节点到第二模式的电源电位。