FORMATION AND USE OF EMBEDDED SOLUTIONS IN NANOSCALE MATERIALS

    公开(公告)号:US20230184752A1

    公开(公告)日:2023-06-15

    申请号:US18066441

    申请日:2022-12-15

    Inventor: Ting Guo

    CPC classification number: G01N33/542 G01N23/223

    Abstract: Provided herein are methods and materials that allow targeting and imaging of interactions between probes and targets. In some embodiments, the probes include nanoscale materials with embedded solutions that can be used to measure physical enhancement by materials under X-ray irradiation. In some embodiments, the methods of the present invention include delivering a probe material to a target that can have a delivered donor material. In some embodiments, methods of the present invention include irradiating the target and determining an optical change in the probe characteristic of a physical enhancement.

    Chemical enhancement by nanomaterials under X-ray irradiation

    公开(公告)号:US09604955B2

    公开(公告)日:2017-03-28

    申请号:US14370733

    申请日:2013-01-11

    Inventor: Ting Guo

    CPC classification number: C07D311/12

    Abstract: A method for dynamic enhancement of chemical reactions by nanomaterials under hard X-ray irradiation. The nanomaterials were gold and platinum nanoparticles, and the chemical reaction employed was the hydroxylation of coumarin carboxylic acid. The reaction yield was enhanced 2000 times over that predicted on the basis of the absorption of X-rays only by the nanoparticles, and the enhancement was found for the first time to depend on the X-ray dose rate. The maximum turnover frequency was measured at 1 16×10-4 s-1 Gy-1. We call this process chemical enhancement, which is defined as the increased yield of a chemical reaction due to the chemical properties of the added materials. The chemical enhancement described here is believed to be ubiquitous and may significantly alter the outcome of chemical reactions under X-ray irradiation with the assistance of nanomaterials.

Patent Agency Ranking