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公开(公告)号:US20040010126A1
公开(公告)日:2004-01-15
申请号:US09968930
申请日:2001-10-01
发明人: David M. Lubman , Timothy J. Barder , Daniel B. Wall , Stephen J. Parus , Maureen T. Kachman , Bathsheba E. Chong , Samir M. Hanash , David E. Misek , Robert Hinderer
IPC分类号: C07K001/20
CPC分类号: G01N27/44773 , C07K1/36 , G01N30/02 , G01N30/461 , G01N30/7233 , G01N30/82 , G01N30/8651 , G01N33/6803 , G01N2030/027 , G01N2030/524 , G01N2030/8813 , G01N2030/8831 , B01D15/325
摘要: The present invention relates to multiphase protein separation methods capable of resolving large numbers of cellular proteins. The methods of the present invention provide protein profile maps for imaging and comparing protein expression patterns. The present invention provides alternatives to traditional 2-D gel separation methods for the screening of protein profiles.
摘要翻译: 本发明涉及能够解析大量细胞蛋白质的多相蛋白质分离方法。 本发明的方法提供用于成像和比较蛋白质表达模式的蛋白质谱图。 本发明提供了用于筛选蛋白质谱的传统的2-D凝胶分离方法的替代方案。
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公开(公告)号:US20020098595A1
公开(公告)日:2002-07-25
申请号:US09778548
申请日:2001-02-07
发明人: David M. Lubman , Timothy J. Barder , Daniel B. Wall , Stephen J. Parus , Maureen T. Kachman , Bathsheba E. Chong , Robert C. North , Fang Yan
IPC分类号: G01N027/26 , G01N027/447 , G01N033/48
CPC分类号: G01N33/6842 , C07K1/36 , G01N27/44795 , G01N30/02 , G01N30/461 , G01N30/463 , G01N30/7233 , G01N30/82 , G01N30/8651 , G01N33/6803 , G01N2030/027 , G01N2030/524 , G01N2030/8804 , G01N2030/8813 , G01N2030/8831 , Y10T436/24 , Y10T436/25 , Y10T436/255 , B01D15/325
摘要: The present invention relates to multi-phase protein separation methods capable of resolving and characterizing large numbers of cellular proteins, including methods for efficiently facilitating the transfer of protein samples between separation phases. In particular, the present invention provides an automated system for the separation, identification, and characterization of protein samples. The present invention thus provides improved methods for the analysis of samples containing large numbers of proteins.
摘要翻译: 本发明涉及能够解析和表征大量细胞蛋白质的多相蛋白质分离方法,包括有效促进蛋白质样品在分离阶段之间转移的方法。 特别地,本发明提供了用于蛋白质样品的分离,鉴定和表征的自动化系统。 因此,本发明提供了用于分析含有大量蛋白质的样品的改进方法。
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