公开(公告)号：US20180333580A1

公开(公告)日：2018-11-22

申请号：US15984626

申请日：2018-05-21

申请人： The Research Foundation for the State University of New York

发明人： John S. CHOI ,  Joseph T. FRANCIS

IPC分类号： A61N1/36 ,  A61B5/00 ,  A61N1/05 ,  A61F2/50

CPC分类号： A61N1/36103 ,  A61B5/0002 ,  A61B5/4064 ,  A61B5/4827 ,  A61B5/685 ,  A61B5/7267 ,  A61B2503/40 ,  A61B2503/42 ,  A61B2562/046 ,  A61F2002/5058 ,  A61F2002/5061 ,  A61N1/0529 ,  A61N1/0534 ,  A61N1/0551 ,  A61N1/36003 ,  A61N1/36139

摘要： Sensory information can be delivered to a subject mammal, for example, for restoring a sense of cutaneous touch and limb motion to the subject mammal. A biomimetic electrical signal is generated based on (a) a stimulation reference signal applied to a somatosensory region of a nervous system of a reference mammal, (b) a stimulated-response signal acquired from a sensory cortex of the reference mammal in response to application of the stimulation reference signal to the thalamic nucleus, and (c) a natural-response signal acquired from the sensory cortex in response to peripheral touch stimuli and/or peripheral nerve stimulation of the reference mammal. The biomimetic electrical signal is applied to a somatosensory region of a nervous system of the subject mammal to induce an activation response, in a sensory cortex of the subject mammal.