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1.发明申请公开(公告)号：US20090257557A1
公开(公告)日：2009-10-15
申请号：US12404881
申请日：2009-03-16
申请人： Thilaka Sumanaweera , Patrick Maguire , Ed Gardner , Jay West
发明人： Thilaka Sumanaweera , Patrick Maguire , Ed Gardner , Jay West
CPC分类号： A61N5/1049 , A61N5/1037 , A61N5/1067 , A61N2005/1059 , A61N2005/1061
摘要： Method and systems are disclosed for radiating a moving target inside a heart. The method includes acquiring sequential volumetric representations of an area of the heart and defining a target tissue region and/or a radiation sensitive structure region in 3D for a first of the representations. The target tissue region and/or radiation sensitive structure region are identified for another of the representations by an analysis of the area of the heart from the first representation and the other representation. Radiation beams to the target tissue region are fired in response to the identified target tissue region and/or radiation sensitive structure region from the other representation.
摘要翻译： 公开了用于在心脏内辐射移动目标的方法和系统。 该方法包括获取心脏区域的顺序体积表示，并且针对第一表示定义3D的目标组织区域和/或辐射敏感结构区域。 通过从第一表示和其他表示的心脏区域的分析来识别目标组织区域和/或辐射敏感结构区域以用于另一个表示。 响应于来自其他表示的识别的目标组织区域和/或辐射敏感结构区域，对目标组织区域的辐射束被点燃。
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2.发明授权公开(公告)号：US07953204B2
公开(公告)日：2011-05-31
申请号：US12404881
申请日：2009-03-16
申请人： Thilaka Sumanaweera , Patrick Maguire , Ed Gardner , Jay West
发明人： Thilaka Sumanaweera , Patrick Maguire , Ed Gardner , Jay West
CPC分类号： A61N5/1049 , A61N5/1037 , A61N5/1067 , A61N2005/1059 , A61N2005/1061
摘要： Method and systems are disclosed for radiating a moving target inside a heart. The method includes acquiring sequential volumetric representations of an area of the heart and defining a target tissue region and/or a radiation sensitive structure region in 3D for a first of the representations. The target tissue region and/or radiation sensitive structure region are identified for another of the representations by an analysis of the area of the heart from the first representation and the other representation. Radiation beams to the target tissue region are fired in response to the identified target tissue region and/or radiation sensitive structure region from the other representation.
摘要翻译： 公开了用于在心脏内辐射移动目标的方法和系统。 该方法包括获取心脏区域的顺序体积表示，并且针对第一表示定义3D的目标组织区域和/或辐射敏感结构区域。 通过从第一表示和其他表示的心脏区域的分析来识别目标组织区域和/或辐射敏感结构区域以用于另一个表示。 响应于来自其他表示的识别的目标组织区域和/或辐射敏感结构区域，对目标组织区域的辐射束被点燃。
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3.发明申请Heart Treatment Kit, System, and Method for Radiosurgically Alleviating Arrhythmia 有权心脏治疗套件，系统和放射外科缓解心律失常的方法公开(公告)号：US20130131425A1
公开(公告)日：2013-05-23
申请号：US13619509
申请日：2012-09-14
申请人： Thilaka Sumanaweera , Ed Gardner , Oliver Blanck , Tao Cai , Darrin Uecker , Patrick Maguire
发明人： Thilaka Sumanaweera , Ed Gardner , Oliver Blanck , Tao Cai , Darrin Uecker , Patrick Maguire
IPC分类号： A61N5/10
CPC分类号： A61N5/1037 , A61B5/0422 , A61B5/7207 , A61B5/7289 , A61B6/03 , A61B6/037 , A61B6/503 , A61B6/504 , A61B8/0883 , A61B8/0891 , A61B90/39 , A61B2034/2051 , A61B2034/2063 , A61N5/1039 , A61N5/1049 , A61N5/1067 , A61N5/1077 , A61N2005/1061
摘要： Radiosurgical treatments of tissues of the heart mitigate arrhythmias and treat other tumerous and non-tumerous disease using an implanted fiducial positioned in or near the heart using cardiac catheterization techniques. The fiducials may be implanted after diagnostic and planning images of the target tissues have been acquired. Fiducial implantation may take place the day of a scheduled radiosurgical treatment. Techniques to accommodate post-planning fiducial implantation may include registration of the implanted fiducial location with the treatment plan, and active fiducials may limit collateral imaging radiation exposure while enhancing tracking accuracy.
摘要翻译： 心脏组织的放射外科治疗可以使用心脏导管插入技术使用位于心脏或心脏附近的植入基准来减轻心律失常并治疗其他肿瘤和非肿瘤性疾病。 可以在诊断和植入目标组织的图像之后植入基准。 基准植入可能是在进行放射外科治疗的当天进行的。 适应规划后基准植入的技术可以包括植入的基准位置与治疗计划的对齐，并且活动的基准可以限制旁路成像辐射暴露，同时增强跟踪精度。
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4.发明授权Heart treatment kit, system, and method for radiosurgically alleviating arrhythmia 有权心脏治疗套件，系统和放射外科减轻心律失常的方法公开(公告)号：US08784290B2
公开(公告)日：2014-07-22
申请号：US12838113
申请日：2010-07-16
申请人： Thilaka Sumanaweera , Ed Gardner , Oliver Blanck , Tao Cai , Darrin Uecker , Patrick Maguire
发明人： Thilaka Sumanaweera , Ed Gardner , Oliver Blanck , Tao Cai , Darrin Uecker , Patrick Maguire
IPC分类号： A61N5/00
CPC分类号： A61N5/1037 , A61B5/0422 , A61B5/7207 , A61B5/7289 , A61B6/03 , A61B6/037 , A61B6/503 , A61B6/504 , A61B8/0883 , A61B8/0891 , A61B90/39 , A61B2034/2051 , A61B2034/2063 , A61N5/1039 , A61N5/1049 , A61N5/1067 , A61N5/1077 , A61N2005/1061
摘要： Radiosurgical treatments of tissues of the heart mitigate arrhythmias and treat other tumerous and non-tumerous disease using an implanted fiducial positioned in or near the heart using cardiac catheterization techniques. The fiducials may be implanted after diagnostic and planning images of the target tissues have been acquired. Fiducial implantation may take place the day of a scheduled radiosurgical treatment. Techniques to accommodate post-planning fiducial implantation may include registration of the implanted fiducial location with the treatment plan, and active fiducials may limit collateral imaging radiation exposure while enhancing tracking accuracy.
摘要翻译： 心脏组织的放射外科治疗可以使用心脏导管插入技术使用位于心脏或心脏附近的植入基准来减轻心律失常并治疗其他肿瘤和非肿瘤性疾病。 可以在诊断和植入目标组织的图像之后植入基准。 基准植入可能是在进行放射外科治疗的当天进行的。 适应规划后基准植入的技术可以包括植入的基准位置与治疗计划的对齐，并且活动的基准可以限制旁路成像辐射暴露，同时增强跟踪精度。
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公开(公告)号：US20110166408A1
公开(公告)日：2011-07-07
申请号：US12838308
申请日：2010-07-16
申请人： Thilaka Sumanaweera , Ed Gardner , Oliver Blanck , Tao Cai , Darrin Uecker , Patrick Maguire
发明人： Thilaka Sumanaweera , Ed Gardner , Oliver Blanck , Tao Cai , Darrin Uecker , Patrick Maguire
CPC分类号： A61N5/1039 , A61B6/032 , A61B6/503 , A61B6/5211 , A61B34/10 , A61B2034/104 , A61B2034/105 , A61B2034/107 , A61N5/103 , G06T15/08 , G06T19/20 , G06T2210/41
摘要： A system that generates a three-dimensional model of a tissue surface, for example the inner surface of the heart from two-dimensional image data slices. On this surface, one or more pattern lines are drawn, e.g., by a physician using a user interface, to designate desired lesion(s) on the surface. From the pattern lines, a three-dimensional volume for a lesion can be determined using known constraints. Advantageously, the series of boundaries generated by the three-dimensional volume may be projected back onto the individual CT scans, which then may be transferred to a standard radiosurgical planning tool. A dose cloud may also be projected on the model to aid in evaluating a plan.
摘要翻译： 生成组织表面的三维模型的系统，例如来自二维图像数据切片的心脏的内表面。 在该表面上，例如由医生使用用户界面绘制一个或多个图案线，以在表面上指定所需的损伤。 从图案线可以使用已知的约束来确定损伤的三维体积。 有利地，由三维体积产生的一系列边界可以被投射回到单独的CT扫描上，然后可以将它们转移到标准的放射外科规划工具。 也可以在模型上投射剂量云以帮助评估计划。
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6.发明授权Heart treatment kit, system, and method for radiosurgically alleviating arrhythmia 有权心脏治疗套件，系统和放射外科减轻心律失常的方法公开(公告)号：US09320916B2
公开(公告)日：2016-04-26
申请号：US13619509
申请日：2012-09-14
申请人： Thilaka Sumanaweera , Ed Gardner , Oliver Blanck , Tao Cai , Darrin Uecker , Patrick Maguire
发明人： Thilaka Sumanaweera , Ed Gardner , Oliver Blanck , Tao Cai , Darrin Uecker , Patrick Maguire
CPC分类号： A61N5/1037 , A61B5/0422 , A61B5/7207 , A61B5/7289 , A61B6/03 , A61B6/037 , A61B6/503 , A61B6/504 , A61B8/0883 , A61B8/0891 , A61B90/39 , A61B2034/2051 , A61B2034/2063 , A61N5/1039 , A61N5/1049 , A61N5/1067 , A61N5/1077 , A61N2005/1061
摘要： Radiosurgical treatments of tissues of the heart mitigate arrhythmias and treat other tumerous and non-tumerous disease using an implanted fiducial positioned in or near the heart using cardiac catheterization techniques. The fiducials may be implanted after diagnostic and planning images of the target tissues have been acquired. Fiducial implantation may take place the day of a scheduled radiosurgical treatment. Techniques to accommodate post-planning fiducial implantation may include registration of the implanted fiducial location with the treatment plan, and active fiducials may limit collateral imaging radiation exposure while enhancing tracking accuracy.
摘要翻译： 心脏组织的放射外科治疗可以使用心脏导管插入技术使用位于心脏或心脏附近的植入基准来减轻心律失常并治疗其他肿瘤和非肿瘤性疾病。 可以在诊断和植入目标组织的图像之后植入基准。 基准植入可能是在进行放射外科治疗的当天进行的。 适应规划后基准植入的技术可以包括植入的基准位置与治疗计划的对齐，并且活动的基准可以限制旁路成像辐射暴露，同时增强跟踪精度。
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7.发明授权公开(公告)号：US08345821B2
公开(公告)日：2013-01-01
申请号：US12900717
申请日：2010-10-08
申请人： Thilaka Sumanaweera , Patrick Maguire , Ed Gardner
发明人： Thilaka Sumanaweera , Patrick Maguire , Ed Gardner
IPC分类号： G21K5/10
CPC分类号： A61N5/1067 , A61B5/0402 , A61B6/032 , A61B6/503 , A61B6/5235 , A61B6/5294 , A61N5/1031 , A61N5/1037 , A61N5/1039 , A61N5/1049 , A61N5/1068 , A61N5/1077 , A61N2005/1061
摘要： Method and systems are disclosed for radiating a moving target inside a heart. The method includes acquiring sequential volumetric representations of an area of the heart and defining a target tissue region and/or a radiation sensitive structure region in 3D for a first of the representations. The target tissue region and/or radiation sensitive structure region are identified for another of the representations by an analysis of the area of the heart from the first representation and the other representation. Radiation beams to the target tissue region are fired in response to the identified target tissue region and/or radiation sensitive structure region from the other representation.
摘要翻译： 公开了用于在心脏内辐射移动目标的方法和系统。 该方法包括获取心脏区域的顺序体积表示，并且针对第一表示定义3D的目标组织区域和/或辐射敏感结构区域。 通过从第一表示和其他表示的心脏区域的分析来识别目标组织区域和/或辐射敏感结构区域以用于另一个表示。 响应于来自其他表示的识别的目标组织区域和/或辐射敏感结构区域，对目标组织区域的辐射束被点燃。
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8.发明申请公开(公告)号：US20110137158A1
公开(公告)日：2011-06-09
申请号：US12900717
申请日：2010-10-08
申请人： Thilaka Sumanaweera , Patrick Maguire , Ed Gardner
发明人： Thilaka Sumanaweera , Patrick Maguire , Ed Gardner
IPC分类号： A61B6/00
CPC分类号： A61N5/1067 , A61B5/0402 , A61B6/032 , A61B6/503 , A61B6/5235 , A61B6/5294 , A61N5/1031 , A61N5/1037 , A61N5/1039 , A61N5/1049 , A61N5/1068 , A61N5/1077 , A61N2005/1061
摘要： Method and systems are disclosed for radiating a moving target inside a heart. The method includes acquiring sequential volumetric representations of an area of the heart and defining a target tissue region and/or a radiation sensitive structure region in 3D for a first of the representations. The target tissue region and/or radiation sensitive structure region are identified for another of the representations by an analysis of the area of the heart from the first representation and the other representation. Radiation beams to the target tissue region are fired in response to the identified target tissue region and/or radiation sensitive structure region from the other representation.
摘要翻译： 公开了用于在心脏内辐射移动目标的方法和系统。 该方法包括获取心脏区域的顺序体积表示，并且针对第一表示定义3D的目标组织区域和/或辐射敏感结构区域。 通过从第一表示和其他表示的心脏区域的分析来识别目标组织区域和/或辐射敏感结构区域以用于另一个表示。 响应于来自其他表示的识别的目标组织区域和/或辐射敏感结构区域，对目标组织区域的辐射束被点燃。
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公开(公告)号：US09205279B2
公开(公告)日：2015-12-08
申请号：US12838308
申请日：2010-07-16
申请人： Thilaka Sumanaweera , Ed Gardner , Oliver Blanck , Tao Cai , Darrin Uecker , Patrick Maguire
发明人： Thilaka Sumanaweera , Ed Gardner , Oliver Blanck , Tao Cai , Darrin Uecker , Patrick Maguire
CPC分类号： A61N5/1039 , A61B6/032 , A61B6/503 , A61B6/5211 , A61B34/10 , A61B2034/104 , A61B2034/105 , A61B2034/107 , A61N5/103 , G06T15/08 , G06T19/20 , G06T2210/41
摘要： A system that generates a three-dimensional model of a tissue surface, for example the inner surface of the heart from two-dimensional image data slices. On this surface, one or more pattern lines are drawn, e.g., by a physician using a user interface, to designate desired lesion(s) on the surface. From the pattern lines, a three-dimensional volume for a lesion can be determined using known constraints. Advantageously, the series of boundaries generated by the three-dimensional volume may be projected back onto the individual CT scans, which then may be transferred to a standard radiosurgical planning tool. A dose cloud may also be projected on the model to aid in evaluating a plan.
摘要翻译： 生成组织表面的三维模型的系统，例如来自二维图像数据切片的心脏的内表面。 在该表面上，例如由医生使用用户界面绘制一个或多个图案线，以在表面上指定所需的损伤。 从图案线可以使用已知的约束来确定损伤的三维体积。 有利地，由三维体积产生的一系列边界可以被投射回到单独的CT扫描上，然后可以将它们转移到标准的放射外科规划工具。 也可以在模型上投射剂量云以帮助评估计划。
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公开(公告)号：US20130102896A1
公开(公告)日：2013-04-25
申请号：US13619064
申请日：2012-09-14
申请人： Thilaka Sumanaweera , Patrick Maguire , Ed Gardner
发明人： Thilaka Sumanaweera , Patrick Maguire , Ed Gardner
IPC分类号： A61N5/10 , A61B6/00 , A61B5/0402 , A61B6/03
CPC分类号： A61N5/1067 , A61B5/0402 , A61B6/032 , A61B6/503 , A61B6/5235 , A61B6/5294 , A61N5/1031 , A61N5/1037 , A61N5/1039 , A61N5/1049 , A61N5/1068 , A61N5/1077 , A61N2005/1061
摘要： Method and systems are disclosed for radiating a moving target inside a heart. The method includes acquiring sequential volumetric representations of an area of the heart and defining a target tissue region and/or a radiation sensitive structure region in 3D for a first of the representations. The target tissue region and/or radiation sensitive structure region are identified for another of the representations by an analysis of the area of the heart from the first representation and the other representation. Radiation beams to the target tissue region are fired in response to the identified target tissue region and/or radiation sensitive structure region from the other representation.
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