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公开(公告)号：US20060176470A1
公开(公告)日：2006-08-10
申请号：US11299266
申请日：2005-12-09
申请人： Thomas Baer , Mark Enright , David Head , Christopher Todd
发明人： Thomas Baer , Mark Enright , David Head , Christopher Todd
IPC分类号： G01N1/00
CPC分类号： G01N1/2813 , G01N1/2806 , G01N1/286 , G01N2001/2833 , G01N2001/284 , G02B21/32
摘要： Systems and methods for laser capture microdissection are disclosed. One method incorporates the step of changing the beam diameter of the laser to adjust the size of the activated area of the transfer film and as a result, the size of the at least one microdissected portion of the sample adhered to the transfer film. Changing the beam diameter while operating the laser in idle mode permits the user to visualize the spot on the desired portion of the tissue sample and simultaneously increase or decrease the beam spot to optimally match the beam spot size with the portion of the tissue to be extracted. This method advantageously provides increased accuracy in microdissection and reduced heating of the tissue sample.
摘要翻译： 公开了用于激光捕获显微切割的系统和方法。 一种方法包括改变激光束的光束直径以调节转印膜的活化区域的尺寸的步骤，结果，样品的至少一个显微切割部分的尺寸粘附到转印膜上。 在空闲模式下操作激光器时改变光束直径允许用户将组织样本的所需部分上的斑点可视化，并且同时增加或减少光束斑点，以将光束斑点尺寸与要提取的组织的部分最佳地匹配 。 该方法有利地提高了组织样本的显微切割和减少加热的增加的精度。
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公开(公告)号：USD532314S1
公开(公告)日：2006-11-21
申请号：US29200720
申请日：2004-03-03
申请人： Christopher Todd
设计人： Christopher Todd
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公开(公告)号：US08797396B2
公开(公告)日：2014-08-05
申请号：US13312322
申请日：2011-12-06
申请人： Lou Dietz , Kurt Kuhlmann , Christopher Todd , Glenn Stark , Barry Rodriguez , Gregory Loney
发明人： Lou Dietz , Kurt Kuhlmann , Christopher Todd , Glenn Stark , Barry Rodriguez , Gregory Loney
CPC分类号： G02B21/365 , G02B21/0016 , G02B21/367 , H04N7/18
摘要： Provided herein are systems methods including a design of a microscope slide scanner for digital pathology applications which provides high quality images and automated batch-mode operation at low cost. The instrument architecture is advantageously based on a convergence of high performance, yet low cost, computing technologies, interfaces and software standards to enable high quality digital microscopy at very low cost. Also provided is a method based in part on a stitching method that allows for dividing an image into a number of overlapping tiles and reconstituting the image with a magnification without substantial loss of accuracy. A scanner is employed in capturing snapshot images. The method allows for overlapping images captured in consecutive snapshots.
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公开(公告)号：US20120092481A1
公开(公告)日：2012-04-19
申请号：US13312322
申请日：2011-12-06
申请人： Lou Dietz , Kurt Kuhlmann , Lokesh Tatke , Suraj Somwanshi , Christopher Todd , Glenn Stark , Barry Rodriguez , Gregory Loney , Bikash Sabata , Ronald L. Allen , Suhas Patil , Sujit Chivate , Prashanth Ravindran , Sanford Barsky
发明人： Lou Dietz , Kurt Kuhlmann , Lokesh Tatke , Suraj Somwanshi , Christopher Todd , Glenn Stark , Barry Rodriguez , Gregory Loney , Bikash Sabata , Ronald L. Allen , Suhas Patil , Sujit Chivate , Prashanth Ravindran , Sanford Barsky
IPC分类号： H04N7/18
CPC分类号： G02B21/365 , G02B21/0016 , G02B21/367 , H04N7/18
摘要： Provided herein are systems methods including a design of a microscope slide scanner for digital pathology applications which provides high quality images and automated batch-mode operation at low cost. The instrument architecture is advantageously based on a convergence of high performance, yet low cost, computing technologies, interfaces and software standards to enable high quality digital microscopy at very low cost. Also provided is a method based in part on a stitching method that allows for dividing an image into a number of overlapping tiles and reconstituting the image with a magnification without substantial loss of accuracy. A scanner is employed in capturing snapshot images. The method allows for overlapping images captured in consecutive snapshots.
摘要翻译： 本文提供了系统方法，其包括用于数字病理应用的显微镜幻灯片扫描器的设计，其以低成本提供高质量图像和自动批量模式操作。 仪器架构有利地基于高性能但是低成本的计算技术，接口和软件标准的融合，以非常低的成本实现高质量数字显微镜。 还提供了一种部分地基于缝合方法的方法，其允许将图像划分成多个重叠的瓦片并且以放大率重新构建图像而不会显着损失精度。 扫描仪用于捕获快照图像。 该方法允许重叠在连续快照中拍摄的图像。
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公开(公告)号：US20120076391A1
公开(公告)日：2012-03-29
申请号：US13312223
申请日：2011-12-06
申请人： Lou Dietz , Kurt Kuhlmann , Lokesh Tatke , Suraj Somwanshi , Christopher Todd , Glenn Stark , Barry Rodriguez , Gregory Loney , Bikash Sabata , Ronald L. Allen , Suhas Patil , Sujit Chivate , Prashanth Ravindran , Sanford Barsky
发明人： Lou Dietz , Kurt Kuhlmann , Lokesh Tatke , Suraj Somwanshi , Christopher Todd , Glenn Stark , Barry Rodriguez , Gregory Loney , Bikash Sabata , Ronald L. Allen , Suhas Patil , Sujit Chivate , Prashanth Ravindran , Sanford Barsky
IPC分类号： G06K9/46
CPC分类号： G02B21/365 , G02B21/0016 , G02B21/367 , H04N7/18
摘要： Provided herein are systems methods including a design of a microscope slide scanner for digital pathology applications which provides high quality images and automated batch-mode operation at low cost. The instrument architecture is advantageously based on a convergence of high performance, yet low cost, computing technologies, interfaces and software standards to enable high quality digital microscopy at very low cost. Also provided is a method based in part on a stitching method that allows for dividing an image into a number of overlapping tiles and reconstituting the image with a magnification without substantial loss of accuracy. A scanner is employed in capturing snapshot images. The method allows for overlapping images captured in consecutive snapshots.
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公开(公告)号：US20120076411A1
公开(公告)日：2012-03-29
申请号：US13312425
申请日：2011-12-06
申请人： Lou Dietz , Kurt Kuhlmann , Lokesh Tatke , Suraj Somwanshi , Christopher Todd , Glenn Stark , Barry Rodriguez , Gregory Loney , Bikash Sabata , Ronald L. Allen , Suhas Patil , Sujit Chivate , Prashanth Ravindran , Sanford Barsky
发明人： Lou Dietz , Kurt Kuhlmann , Lokesh Tatke , Suraj Somwanshi , Christopher Todd , Glenn Stark , Barry Rodriguez , Gregory Loney , Bikash Sabata , Ronald L. Allen , Suhas Patil , Sujit Chivate , Prashanth Ravindran , Sanford Barsky
IPC分类号： G06K9/34
CPC分类号： G02B21/365 , G02B21/0016 , G02B21/367 , H04N7/18
摘要： Provided herein are systems methods including a design of a microscope slide scanner for digital pathology applications which provides high quality images and automated batch-mode operation at low cost. The instrument architecture is advantageously based on a convergence of high performance, yet low cost, computing technologies, interfaces and software standards to enable high quality digital microscopy at very low cost. Also provided is a method based in part on a stitching method that allows for dividing an image into a number of overlapping tiles and reconstituting the image with a magnification without substantial loss of accuracy. A scanner is employed in capturing snapshot images. The method allows for overlapping images captured in consecutive snapshots.
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公开(公告)号：US20110002860A1
公开(公告)日：2011-01-06
申请号：US12733798
申请日：2008-09-18
申请人： Christopher Todd , Sylvia Trimble
发明人： Christopher Todd , Sylvia Trimble
摘要： The present invention relates to a tooth bleaching preparation comprising an adduct formulated from starting materials comprising peroxide, urea and an alkali metal polyphosphate, the adduct being provided in the preparation in aqueous conditions and the preparation having a pH in aqueous solution which rises on dilution of the solution.
摘要翻译： 本发明涉及一种牙齿漂白制剂，其包括由起始原料配制的加合物，所述原料包括过氧化物，尿素和碱金属多磷酸盐，所述加合物在水性条件下在制剂中提供，并且制备物在水溶液中的pH值在稀释度 解决方案。
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公开(公告)号：US20080240613A1
公开(公告)日：2008-10-02
申请号：US12054309
申请日：2008-03-24
申请人： Lou Dietz , Kurt Kuhlmann , Lokesh Tatke , Suraj Somwanshi , Christopher Todd , Glenn Stark , Barry Rodriguez , Gregory Loney , Bikash Sabata , Ronald L. Allen , Suhas Patil , Sujit Chivate , Prashanth Ravindran , Sanford Barsky
发明人： Lou Dietz , Kurt Kuhlmann , Lokesh Tatke , Suraj Somwanshi , Christopher Todd , Glenn Stark , Barry Rodriguez , Gregory Loney , Bikash Sabata , Ronald L. Allen , Suhas Patil , Sujit Chivate , Prashanth Ravindran , Sanford Barsky
IPC分类号： G06K9/36
CPC分类号： G02B21/365 , G02B21/0016 , G02B21/367 , H04N7/18
摘要： Provided herein are systems methods including a design of a microscope slide scanner for digital pathology applications which provides high quality images and automated batch-mode operation at low cost. The instrument architecture is advantageously based on a convergence of high performance, yet low cost, computing technologies, interfaces and software standards to enable high quality digital microscopy at very low cost. Also provided is a method based in part on a stitching method that allows for dividing an image into a number of overlapping tiles and reconstituting the image with a magnification without substantial loss of accuracy. A scanner is employed in capturing snapshot images. The method allows for overlapping images captured in consecutive snapshots.
摘要翻译： 本文提供了系统方法，其包括用于数字病理应用的显微镜幻灯片扫描器的设计，其以低成本提供高质量图像和自动批量模式操作。 仪器架构有利地基于高性能但是低成本的计算技术，接口和软件标准的融合，以非常低的成本实现高质量数字显微镜。 还提供了一种部分地基于缝合方法的方法，其允许将图像划分成多个重叠的瓦片并且以放大率重新构建图像而不会显着损失精度。 扫描仪用于捕获快照图像。 该方法允许重叠在连续快照中拍摄的图像。
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公开(公告)号：USD525132S1
公开(公告)日：2006-07-18
申请号：US29203921
申请日：2004-04-21
申请人： Christopher Todd
设计人： Christopher Todd
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公开(公告)号：US08815217B2
公开(公告)日：2014-08-26
申请号：US12733798
申请日：2008-09-18
申请人： Christopher Todd , Sylvia Trimble
发明人： Christopher Todd , Sylvia Trimble
摘要： The present invention relates to a tooth bleaching preparation comprising an adduct formulated from starting materials comprising peroxide, urea and an alkali metal polyphosphate, the adduct being provided in the preparation in aqueous conditions and the preparation having a pH in aqueous solution which rises on dilution of the solution.
摘要翻译： 本发明涉及一种牙齿漂白制剂，其包括由起始原料配制的加合物，所述原料包括过氧化物，尿素和碱金属多磷酸盐，所述加合物在水性条件下在制剂中提供，并且制备物在水溶液中的pH值在稀释度 解决方案。
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