公开(公告)号：US5852217A

公开(公告)日：1998-12-22

申请号：US888394

申请日：1997-07-07

申请人： Thomas Haas ,  Dietrich Arntz ,  Karl-Ludwig Weber ,  Willi Hofen ,  Stefan Wieland

发明人： Thomas Haas ,  Dietrich Arntz ,  Karl-Ludwig Weber ,  Willi Hofen ,  Stefan Wieland

IPC分类号： C07C209/24 ,  C07B61/00 ,  C07C209/26 ,  C07C209/48 ,  C07C209/52 ,  C07C211/01 ,  C07C211/33 ,  C07C211/36 ,  C07C211/43

CPC分类号： C07C209/26 ,  C07C209/48 ,  C07C211/36 ,  C07C2101/14

摘要： This invention relates to a process for the production of primary and/or secondary amines from oxo compounds by catalytic imination of the oxo compound with ammonia or a primary amine and subsequent hydrogenation. Imination proceeds according to the invention in the presence of a novel imination catalyst, namely an organopolysiloxane containing sulphonate groups. This imination catalyst is distinguished by elevated activity. The process is in particular suitable for the production of isophorone diamine from isophorone nitrile, wherein it has proved possible to reduce the content of secondary products and to increase yield.

摘要翻译： 本发明涉及通过氧化合物与氨或伯胺的催化模拟和随后的氢化从氧代化合物制备伯胺和/或仲胺的方法。 根据本发明，在新型酰化催化剂，即含有磺酸酯基团的有机聚硅氧烷的存在下进行本发明。 该仿制催化剂的活性升高。 该方法特别适用于从异佛尔酮腈生产异佛尔酮二胺，其中证明可以减少二次产物的含量并提高产率。

公开(公告)号：US6011179A

公开(公告)日：2000-01-04

申请号：US182196

申请日：1998-10-30

申请人： Thomas Haas ,  Karl Ludwig Weber ,  Klaus Stadtmuller ,  Willi Hofen ,  Rudolf Vanheertum

发明人： Thomas Haas ,  Karl Ludwig Weber ,  Klaus Stadtmuller ,  Willi Hofen ,  Rudolf Vanheertum

IPC分类号： B01J23/75 ,  C07B61/00 ,  C07C209/48 ,  C07C209/52 ,  C07C211/36 ,  C07C209/32

CPC分类号： C07C209/52 ,  C07C209/48 ,  C07C2101/14

摘要： A process for the production of primary and/or secondary amines from imines or nitriles, comprising an aminating hydrogenation of imine or of nitrile with hydrogen in the presence of ammonia, of a hydrogenation catalyst based on cobalt, nickel, ruthenium or mixtures of these metals and of a base, at a temperature within the range of 50.degree. C. to 200.degree. C. and at a pressure within the range of 0.3 to 30 MPa. The yield of amine is increased by the use of a quaternary ammonium hydroxide as base. Preferably a tetraalkylammonium hydroxide is used in a quantity of from 0.01 to 100 mMol per mol of amine or of nitrile. The process is suitable in particular for the production of isophoronediamine from isophorone nitrile imine.

摘要翻译： 一种由亚胺或腈生产伯胺和/或仲胺的方法，包括在氨存在下亚胺或腈与氢的氨化氢化，基于钴，镍，钌的氢化催化剂或这些金属的混合物 在50〜200℃的范围内，压力为0.3〜30MPa的范围内进行。 通过使用季铵氢氧化物作为碱来增加胺的产率。 优选氢氧化四烷基铵的用量为每摩尔胺或腈的0.01至100mMol。 该方法特别适用于从异佛尔酮腈亚胺生产异佛尔酮二胺。

公开(公告)号：US5679860A

公开(公告)日：1997-10-21

申请号：US739044

申请日：1996-10-28

申请人： Thomas Haas ,  Roland Burmeister ,  Dietrich Arntz ,  Karl-Ludwig Weber ,  Monika Berweiler

发明人： Thomas Haas ,  Roland Burmeister ,  Dietrich Arntz ,  Karl-Ludwig Weber ,  Monika Berweiler

IPC分类号： B01J21/06 ,  C07B61/00 ,  C07C209/48 ,  C07C209/52 ,  C07C211/36 ,  C07C209/32

CPC分类号： C07C211/36 ,  C07C209/48 ,  C07C209/52 ,  C07C2101/14

摘要： A process for producing 3-aminomethyl-3,5,5-trimethylcyclohexyl amine (isophorone diamine) from isophorone nitrile. Isophorone nitrile is iminated in a first stage and then the reaction mixture is subjected to aminating hydrogenation in a second stage in the presence of a fixed bed hydrogenation catalyst based on Raney cobalt. The fixed bed hydrogenation catalyst is produced in a special manner by mixing a powdery Co--containing Raney alloy with powdery cobalt, sintering the powdery mixture to shaped moldings and then activating by leaching with alkali hydroxide solution. The yield and/or space-time yield in isophorone diamine production can be increased.

摘要翻译： 由异佛尔酮腈生产3-氨基甲基-3,5,5-三甲基环己胺（异佛尔酮二胺）的方法。 在第一阶段中将异佛尔酮腈进行酰化，然后在基于阮内钴的固定床氢化催化剂的存在下，将反应混合物在第二阶段进行氨化氢化。 固定床加氢催化剂以特殊的方式通过将粉末状含钴阮内合金与粉末状钴混合，将粉末状混合物烧结成型成形体，然后通过用碱金属氢氧化物溶液浸出而活化。 可以增加异佛尔酮二胺生产中的产率和/或时空产率。

公开(公告)号：US20060135826A1

公开(公告)日：2006-06-22

申请号：US11312237

申请日：2005-12-19

申请人： Willi Hofen ,  Thomas Haas ,  Barbel Kolbe

发明人： Willi Hofen ,  Thomas Haas ,  Barbel Kolbe

IPC分类号： C07C29/74

CPC分类号： B01D1/26 ,  B01D3/146 ,  B01D3/148 ,  C07C29/80 ,  Y02P70/34 ,  C07C31/04

摘要： A process for recovering methanol from mixtures containing methanol and water, comprising multistage evaporation with heat integration, wherein the pressure is reduced from each stage to the next, and a downstream series of distillation stages with heat integration, wherein the pressure is increased from each stage to the next. The process reduces the amount of energy required for methanol recovery.

摘要翻译： 一种从含有甲醇和水的混合物中回收甲醇的方法，包括具有热积分的多级蒸发，其中压力从每个阶段下降到下一个阶段，以及下游一系列具有热积分的蒸馏阶段，其中压力从每个阶段增加 到下一个。 该方法减少甲醇回收所需的能量。

公开(公告)号：US06596883B2

公开(公告)日：2003-07-22

申请号：US10226766

申请日：2002-08-23

申请人： Willi Hofen ,  Thomas Haas ,  Wolfgang Wöll ,  Georg Thiele

发明人： Willi Hofen ,  Thomas Haas ,  Wolfgang Wöll ,  Georg Thiele

IPC分类号： C07D30132

CPC分类号： C07D301/12

摘要： A process for the working up of a product stream from the epoxidation of olefins that contains olefin, olefin oxide, water-miscible organic solvent and water, by separating this product stream into an overhead product containing olefin, olefin oxide and organic solvent, and into a bottom product containing organic solvent and water, wherein the separation takes place in a pre-evaporator with less than 10 theoretical separation stages at a pressure of 1.5 to less than 3 bar, and 20 to 60% of the total amount of organic solvent introduced with the product stream is removed with the overhead product and the balance remains in the bottom product. A process for the epoxidation of olefins that includes this working up stage is also disclosed.

公开(公告)号：US07169945B2

公开(公告)日：2007-01-30

申请号：US10724300

申请日：2003-11-26

申请人： Thomas Haas ,  Willi Hofen ,  Wolfgang Wöll ,  Claudia Brasse ,  Guido Stochniol ,  Norbert Ullrich

发明人： Thomas Haas ,  Willi Hofen ,  Wolfgang Wöll ,  Claudia Brasse ,  Guido Stochniol ,  Norbert Ullrich

IPC分类号： C07D301/12

CPC分类号： C07D301/12 ,  Y02P20/584

摘要： A process for the catalytic epoxidation of olefins in the presence of a titanium containing zeolite catalyst and a polar solvent whereby the deactivation of the catalyst upon recycling of the solvent has been considerably reduced. In the process one or more nitrogen containing compounds are introduced at some stage, a solvent stream is recovered, treated to contain less than 50 wppm nitrogen in the form of organic nitrogen compounds and at least a part of it is recycled to the epoxidation step. Also disclosed is a process for the catalytic epoxidation of propene which integrates the treatment and recycle of the solvent into the workup of the reaction mixture.

摘要翻译： 一种在含钛沸石催化剂和极性溶剂的存在下烯烃的催化环氧化方法，从而显着减少了在溶剂再循环时催化剂失活。 在该过程中，在一些阶段引入一种或多种含氮化合物，回收溶剂流，将其处理为含有少于50wppm氮的有机氮化合物形式，并将其至少一部分再循环至环氧化步骤。 还公开了丙烯的催化环氧化方法，其将溶剂的处理和再循环整合到反应混合物的后处理中。

公开(公告)号：US06720436B2

公开(公告)日：2004-04-13

申请号：US10384217

申请日：2003-03-07

申请人： Willi Hofen ,  Georg Thiele ,  Thomas Haas ,  Wolfgang Wöll ,  Percy Kampeis ,  Bärbel Kolbe

发明人： Willi Hofen ,  Georg Thiele ,  Thomas Haas ,  Wolfgang Wöll ,  Percy Kampeis ,  Bärbel Kolbe

IPC分类号： C07D30112

CPC分类号： C07D301/12

摘要： A process for the catalytic epoxidation of olefins in at least one reaction stage comprising: (a) reacting the olefin with hydrogen peroxide in an organic, water-miscible solvent in the presence of a titanium silicalite catalyst in a reactor while continuously feeding an inert gas stream into the reactor, (b) continuously removing an exit gas stream containing olefin oxide, unreacted olefin, oxygen and inert gas from the reactor, (c) bringing the exit gas stream into contact in an absorption unit with the same solvent as used in the reaction stage, (d) removing a solvent stream loaded with olefin and olefin oxide from the absorption unit and (e) discharging an gas stream containing oxygen and the inert gas from the absorption unit.

摘要翻译： 一种用于在至少一个反应阶段中对烯烃进行催化环氧化的方法，包括：（a）在反应器中在钛硅沸石催化剂存在下，使烯烃与有机的水混溶性溶剂中的过氧化氢反应，同时连续进料惰性气体 （b）从反应器中连续除去含有烯烃氧化物，未反应的烯烃，氧和惰性气体的出口气流，（c）使出口气流与吸收单元中的相同溶剂接触， 反应阶段，（d）从吸收单元除去负载有烯烃和烯烃氧化物的溶剂流，和（e）从吸收单元排出含有氧和惰性气体的气流。

公开(公告)号：US20050148797A1

公开(公告)日：2005-07-07

申请号：US10516319

申请日：2003-06-25

申请人： Bernd Jaeger ,  Thomas Haas ,  Guido Stochniol ,  Christian Lettmann ,  Willi Hofen ,  Klaus Stadtmuller ,  Jorg Lotz

发明人： Bernd Jaeger ,  Thomas Haas ,  Guido Stochniol ,  Christian Lettmann ,  Willi Hofen ,  Klaus Stadtmuller ,  Jorg Lotz

IPC分类号： C07B61/00 ,  C07C209/72 ,  C07C211/36 ,  C07C29/72

CPC分类号： C07C209/72 ,  C07C211/36

摘要： The invention relates to a process for increasing the selectivity of the hydrogenation of 4,4′-diaminodiphenylmethane (4,4′-MDA) to diaminodicyclohexylmethane (4,4′-HMDA) by catalytic hydrogenation of a mixture containing 4,4′-MDA as the main component and its mono-N-methyl derivative as a secondary component. According to the invention, the hydrogenation is terminated before a conversion of 4,4′-MDA to 4,4′-HMDA of 99% is achieved. Under these conditions, a substantially smaller proportion of the N-methyl-4,4′-MDA is hydrogenated to N-methyl-4,4-HMDA.

摘要翻译： 本发明涉及通过催化氢化含有4,4'-二氨基二苯基甲烷（4,4'-MDA）的混合物的方法提高4,4'-二氨基二苯基甲烷（4,4'-MDA） MDA为主要成分，其单-N-甲基衍生物为次要成分。 根据本发明，在将4,4'-MDA转化为99％的4,4'-HMDA之前终止氢化。 在这些条件下，将大部分比例的N-甲基-4,4'-MDA氢化成N-甲基-4,4-HMDA。

公开(公告)号：US06878836B2

公开(公告)日：2005-04-12

申请号：US10839572

申请日：2004-05-05

申请人： Thomas Haas ,  Claudia Brasse ,  Wolfgang Wöll ,  Willi Hofen ,  Bernd Jaeger ,  Guido Stochniol ,  Norbert Ullrich

发明人： Thomas Haas ,  Claudia Brasse ,  Wolfgang Wöll ,  Willi Hofen ,  Bernd Jaeger ,  Guido Stochniol ,  Norbert Ullrich

IPC分类号： C07D301/12 ,  C07D303/04

CPC分类号： C07D303/04 ,  C07D301/12 ,  Y02P20/584

摘要： A process for the continuous epoxidation of propene with hydrogen peroxide in the presence of a titanium silicalite catalyst and a methanol solvent, wherein the catalyst is periodically regenerated by washing with a methanol solvent at a temperature of at least 100° C. and the epoxidation reaction is carried out for periods of more than 300 h between two regeneration steps.

摘要翻译： 一种在钛硅沸石催化剂和甲醇溶剂存在下用过氧化氢连续环氧化丙烯的方法，其中催化剂通过在至少100℃的温度下用甲醇溶剂洗涤并周期性地再生，并且环氧化反应 在两个再生步骤之间进行超过300小时的时间。

公开(公告)号：US06838572B2

公开(公告)日：2005-01-04

申请号：US10669993

申请日：2003-09-24

申请人： Thomas Haas ,  Claudia Brasse ,  Guido Stochniol ,  Willi Hofen ,  Wolfgang Wöll ,  Georg Thiele

发明人： Thomas Haas ,  Claudia Brasse ,  Guido Stochniol ,  Willi Hofen ,  Wolfgang Wöll ,  Georg Thiele

IPC分类号： C01B15/013 ,  C01B15/023 ,  C07D301/12

CPC分类号： C01B15/013 ,  C01B15/023 ,  C07D301/12

摘要： A continuous process for the epoxidation of olefins with hydrogen peroxide in the presence of a heterogeneous catalyst promoting the epoxidation reaction, whereby the aqueous reaction mixture contains i) an olefin; ii) hydrogen peroxide; iii) less than 100 wppm of alkali metals, earth alkali metals, both irrespective whether in ionic, complex or covalently bonded form, bases or cations of bases having a pkB of less than 4.5, or combinations thereof; and, iv) at least 100 wppm of bases or cations of bases having a pkB of at least 4.5 or combinations thereof, whereby the wppm are based on the total weight of hydrogen peroxide in the reaction mixture.

摘要翻译： 在促进环氧化反应的多相催化剂的存在下用过氧化氢环氧化烯烃的连续方法，由此含水反应混合物含有i）烯烃; ii）过氧化氢; iii）小于100wppm的碱金属，碱土金属，无论是在离子，复合或共价键合的形式，碱性或pKB小于4.5的碱的阳离子，或其组合; 和iv）至少100wppm的pkB至少为4.5的碱或碱的阳离子或其组合，其中wppm是基于反应混合物中过氧化氢的总重量。