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公开(公告)号：US06688492B2
公开(公告)日：2004-02-10
申请号：US10056873
申请日：2002-01-24
IPC分类号： G01F1100
CPC分类号： B65D83/265
摘要： A valve assembly can automatically dispense aerosol content from an aerosol container at predetermined intervals without the use of electric power. A diaphragm at least partially defines an accumulation chamber that receives gas propellant from a portion of the can during an accumulation phase. Once the internal pressure of the accumulation chamber reaches a predetermined threshold, the diaphragm moves, carrying with it a seal so as to unseal an outlet channel, and thereby initiate a spray burst of the main active chemical. The diaphragm assumes its original position when the pressure within the accumulation chamber falls below a threshold pressure.
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公开(公告)号：US06837396B2
公开(公告)日：2005-01-04
申请号：US10729173
申请日：2003-12-05
CPC分类号： B65D83/265
摘要： A valve assembly can automatically dispense aerosol content from an aerosol container at predetermined intervals without the use of electric power. A diaphragm at least partially defines an accumulation chamber that receives gas propellant from a portion of the can during an accumulation phase. Once the internal pressure of the accumulation chamber reaches a predetermined threshold, the diaphragm moves, carrying with it a seal so as to unseal an outlet channel, and thereby initiate a spray burst of the main active chemical. The diaphragm assumes its original position when the pressure within the accumulation chamber falls below a threshold pressure.
摘要翻译： 阀组件可以在不使用电力的情况下以预定间隔自动从气溶胶容器分配气溶胶含量。 隔膜至少部分地限定在积聚阶段期间从罐的一部分接收气体推进剂的积聚室。 一旦积聚室的内部压力达到预定的阈值，隔膜就会移动，携带密封件，以便开启出口通道，从而引发主活性化学品的喷雾。 当积聚室内的压力低于阈值压力时，隔膜承受其原始位置。
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公开(公告)号：US06588627B2
公开(公告)日：2003-07-08
申请号：US10002664
申请日：2001-10-31
IPC分类号： G01F1100
CPC分类号： B65D83/265
摘要： A valve assembly can automatically dispense aerosol content from an aerosol container at predetermined intervals without the use of electric power. A diaphragm at least partially defines an accumulation chamber that receives aerosol content from the can during an accumulation phase. Once the internal pressure of the accumulation chamber reaches a predetermined threshold, the diaphragm moves, carrying with it a leg so as to unseal a valve stem, and thereby initiate a spray burst. The diaphragm assumes its original position when the pressure within the accumulation chamber falls below a threshold pressure. A barrier prevents the aerosol container from resupplying the accumulation chamber at a high rate during the spray phase, preferably due to a textured interface between the barrier and a passageway in which it is housed.
摘要翻译： 阀组件可以在不使用电力的情况下以预定间隔自动从气溶胶容器分配气溶胶含量。 隔膜至少部分地限定在积聚阶段期间从罐接收气溶胶含量的积聚室。 一旦积聚室的内部压力达到预定的阈值，隔膜就会移动，携带腿部，以便开启阀杆，从而开始喷雾。 当积聚室内的压力低于阈值压力时，隔膜承受其原始位置。 屏障防止气雾剂容器在喷雾阶段以高速率重新供应积聚室，优选地是由于屏障和其所容纳的通道之间的纹理界面。
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公开(公告)号：US06533141B1
公开(公告)日：2003-03-18
申请号：US10002657
申请日：2001-10-31
IPC分类号： G01F1100
CPC分类号： B65D83/265
摘要： An valve assembly is provided that automatically dispenses aerosol content from a can at predetermined intervals. A diaphragm at least partially defines an accumulation chamber that receives aerosol content from the can during an accumulation phase. Once the internal pressure of the accumulation chamber reaches a predetermined threshold, the diaphragm flexes to initiate a spray phase, during which the aerosol content is delivered from the accumulation chamber to the ambient environment. A rotatable pawl provides resistive pressure and control of diaphragm movement.
摘要翻译： 提供了一种阀组件，其以预定间隔自动地从罐中分配气溶胶含量。 隔膜至少部分地限定在积聚阶段期间从罐接收气溶胶含量的积聚室。 一旦积聚室的内部压力达到预定的阈值，膜片就会弯曲以启动喷雾阶段，在此期间气溶胶含量从积聚室输送到周围环境。 可旋转的棘爪提供阻力和控制隔膜的运动。
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公开(公告)号：US06612464B2
公开(公告)日：2003-09-02
申请号：US10010319
申请日：2001-11-13
IPC分类号： G01F1100
CPC分类号： B65D83/265
摘要： A valve assembly can automatically dispense aerosol content from an aerosol container at predetermined intervals without the use of electric power. A diaphragm at least partially defines an accumulation chamber that receives aerosol content from the can during an accumulation phase. Once the internal pressure of the accumulation chamber reaches a predetermined threshold, the diaphragm moves axially, carrying with it a leg so as to unseal an outlet, and thereby initiate a spray burst. A pawl extends from the diaphragm, and engages a retention surface to resist movement of the diaphragm and prolong the accumulation phase. The diaphragm assumes its original position when the pressure within the accumulation chamber falls below a threshold pressure.
摘要翻译： 阀组件可以在不使用电力的情况下以预定间隔自动从气溶胶容器分配气溶胶含量。 隔膜至少部分地限定在积聚阶段期间从罐接收气溶胶含量的积聚室。 一旦积聚室的内部压力达到预定的阈值，隔膜就会轴向移动，并带有支脚，以便开启出口，从而开始喷雾。 棘爪从隔膜延伸并与保持表面接合以阻止隔膜的移动并延长累积阶段。 当积聚室内的压力低于阈值压力时，隔膜承受其原始位置。
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公开(公告)号：US5837870A
公开(公告)日：1998-11-17
申请号：US828923
申请日：1997-03-28
申请人： Bruce A. Pearlman , William R. Perrault , Michael R. Barbachyn , Peter R. Manninen , Dana S. Toops , David J. Houser , Thomas J. Fleck
发明人： Bruce A. Pearlman , William R. Perrault , Michael R. Barbachyn , Peter R. Manninen , Dana S. Toops , David J. Houser , Thomas J. Fleck
IPC分类号： C07D263/20 , C07D263/24 , C07D295/00 , C07D413/04 , C07D413/10 , C07D487/04 , C07D521/00 , C07D249/16
CPC分类号： C07D487/04 , C07D231/12 , C07D233/56 , C07D249/08 , C07D263/20 , C07D263/24 , C07D413/04 , C07D413/10
摘要： The present invention includes processes for producing 5-hydroxymethyl substituted oxazolidinone alcohols (III) from carbamates (IIA) or a trifluoroacetamide (IIB) using a dihydroxy compound (I) or glycidol (IV) starting material and for the transformation of the hydroxymethyl substituted oxazolidinone alcohols (III) to the corresponding amino compounds, 5-aminomethyl substituted oxazolidinone amines (VII) which are acylated to form commercially useful antibacterial 5-acylamidomethyl substituted oxazolidinone (VIII).
摘要翻译： 本发明包括使用二羟基化合物（I）或缩水甘油（IV）起始物从氨基甲酸酯（IIA）或三氟乙酰胺（IIB）制备5-羟甲基取代的恶唑烷酮醇（III）和用于羟甲基取代的恶唑烷酮 醇（III）与相应的氨基化合物，5-氨基甲基取代的恶唑烷酮胺（VII），其被酰化形成商业上有用的抗菌5-酰氨基甲基取代的恶唑烷酮（VIII）。
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公开(公告)号：US5961043A
公开(公告)日：1999-10-05
申请号：US105486
申请日：1998-06-26
CPC分类号： A01M1/2055 , A01M1/2044 , A61L9/12 , Y10S206/806
摘要： A device supports and dispenses volatile materials. The device is self-supporting and has a tent-like configuration. It can be hung from a bar. One of its side panels is connected to another by a tab and slot, or tab and pocket, arrangement above a base. The base connects the side panels. There is a reservoir for dispensing the volatile material which is mounted on one of the side panels, with a rear of the reservoir being positioned between two of the panels above the base.
摘要翻译： 设备支持和分配挥发性材料。 该设备是自支撑的，具有帐篷式配置。 它可以从酒吧挂。 其一个侧板通过在基座上方的突片和槽，或突出部和口袋连接到另一个。 底座连接侧面板。 存在用于分配安装在一个侧板上的挥发性材料的储存器，储存器的后部位于基座上方的两个面板之间。
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8.发明授权公开(公告)号：US06978914B2
公开(公告)日：2005-12-27
申请号：US10496925
申请日：2002-11-27
申请人： Paul E. Furner , Kenneth W. Michaels , Thomas J. Szymczak , Edward J. Kunesh , David P. Mather , David J. Houser , William E. McCracken
发明人： Paul E. Furner , Kenneth W. Michaels , Thomas J. Szymczak , Edward J. Kunesh , David P. Mather , David J. Houser , William E. McCracken
CPC分类号： B65D83/72 , A45D27/02 , B05B12/10 , B65D83/384 , B65D83/388
摘要： Apparatus for placing contents of a first container in fluid communication with a delivery apparatus includes an actuating element carried by the delivery apparatus and a valve element carried by the first container. At least one of the actuating element and the valve element defines a flow path from the first container to the delivery apparatus when the actuating element and the valve element are engaged with one another. The actuating element is engageable with a circular cylindrical valve of a second container to prevent flow of contents of the second container into the delivery apparatus.
摘要翻译： 用于放置与输送装置流体连通的第一容器的内容物的装置包括由输送装置承载的致动元件和由第一容器承载的阀元件。 当致动元件和阀元件彼此接合时，致动元件和阀元件中的至少一个限定从第一容器到输送设备的流动路径。 致动元件可与第二容器的圆柱形阀接合，以防止第二容器的内容物流入输送设备。
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9.发明授权End of use and time duration indicator system and method based on volatile dye 失效基于挥发性染料的使用期限和持续时间指标体系及方法公开(公告)号：US06790670B2
公开(公告)日：2004-09-14
申请号：US09973504
申请日：2001-10-09
申请人： Murthy S. Munagavalasa , Stacey L. Forkner , Stanley J. Flashinski , Adam Hagop Buchaklian , David J. Houser
发明人： Murthy S. Munagavalasa , Stacey L. Forkner , Stanley J. Flashinski , Adam Hagop Buchaklian , David J. Houser
IPC分类号： G01N2178
CPC分类号： G01N31/229
摘要： A time duration of end of product life indicator is disclosed which utilizes a volatile dye coated or impregnated into a substrate or carrier. The dye evaporates as a volatile component of the product evaporates thereby changing the color of the substrate or carrier. The consumer is alerted to the depletion of the volatile component of the product when the substrate or carrier changes from a colored or dyed state to an uncolored state. As a result, a visual time duration or end of product life indicator is provided.
摘要翻译： 公开了产品寿命指示剂结束的持续时间，其使用涂布或浸渍到基底或载体中的挥发性染料。 当产物的挥发性成分蒸发时，染料蒸发，从而改变基材或载体的颜色。 当衬底或载体从着色或染色状态变为未着色状态时，消费者被警告消耗产品的挥发性成分。 因此，提供了视觉持续时间或产品寿命指示符的结束。
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公开(公告)号：US4238398A
公开(公告)日：1980-12-09
申请号：US89967
申请日：1979-10-31
申请人： Paul F. Wiley , David J. Houser
发明人： Paul F. Wiley , David J. Houser
IPC分类号： C07D493/08 , C07D319/08
CPC分类号： C07D493/08
摘要： Novel antibiotics, 7(R)-0-alkylnogalarols, prepared by acidic alcoholysis of nogalamycin of nogalarol, which are active against various microorganisms, for example, Bacillus subtilis, Streptococcus pyogenes, Sarcina lutea, Bacteroides fragilis, Clostridium perfringens, and Mycobacterium avium. Thus, they can be used to inhibit the growth of the above microorganisms in various environments. Further, the invention compounds possess unexpected superior activity against P388 leukemia infection in laboratory mice. Thus, the compounds of the invention can be used to treat laboratory mice infected with P388 leukemia.
摘要翻译： 新的抗生素，通过对各种微生物，例如枯草芽孢杆菌，化脓性链球菌，麻黄碱，脆弱拟杆菌，产气荚膜梭菌和鸟分枝杆菌具有活性的诺加拉林的诺加拉霉素的酸性醇解制备的7-（R）-O-烷基核酸。 因此，它们可用于抑制各种环境中上述微生物的生长。 此外，本发明化合物在实验室小鼠中具有对P388白血病感染的意想不到的优异活性。 因此，本发明的化合物可用于治疗P388白血病感染的实验室小鼠。
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