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105 条记录 (耗时 0.026 秒)

    Prognosis prediction for melanoma cancer
    5.
    发明授权
    Prognosis prediction for melanoma cancer 有权
    黑色素瘤预后预测

    公开(公告)号：US08822149B2

    公开(公告)日：2014-09-02

    申请号：US12592385

    申请日：2009-11-23

    申请人： Michael Alan Black ,  Jonathan Cebon ,  Parry John Guilford ,  Thomas John

    发明人： Michael Alan Black ,  Jonathan Cebon ,  Parry John Guilford ,  Thomas John

    IPC分类号： C12Q1/68 ,  C12P19/34 ,  C07H21/02 ,  C07H21/04

    CPC分类号： C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/16 ,  G06F19/00 ,  G16H50/30

    摘要： The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.

    摘要翻译： 本发明涉及预后标志物和预后特征，以及用于确定患者中癌症预后的组合物和方法，特别是对于黑素瘤。 具体而言，本发明涉及遗传和蛋白质标记物用于基于标记物和标记物的标记来预测癌症进展风险（例如黑素瘤）的用途。 在各个方面，本发明提供了基于预后癌症标志物，特别是黑素瘤预后标志物的方法，组合物，试剂盒和装置，以帮助癌症的预后和治疗。

    Prognosis prediction for melanoma cancer
    6.
    发明申请
    Prognosis prediction for melanoma cancer 有权
    黑色素瘤预后预测

    公开(公告)号：US20100136553A1

    公开(公告)日：2010-06-03

    申请号：US12592385

    申请日：2009-11-23

    申请人： Michael Alan Black ,  Jonathan Cebon ,  Parry John Guilford ,  Thomas John

    发明人： Michael Alan Black ,  Jonathan Cebon ,  Parry John Guilford ,  Thomas John

    IPC分类号： C12Q1/68 ,  C07H21/00

    CPC分类号： C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/16 ,  G06F19/00 ,  G16H50/30

    摘要： The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.

    摘要翻译： 本发明涉及预后标志物和预后特征，以及用于确定患者中癌症预后的组合物和方法，特别是对于黑素瘤。 具体而言，本发明涉及遗传和蛋白质标记物用于基于标记物和标记物的标记来预测癌症进展风险（例如黑素瘤）的用途。 在各个方面，本发明提供了基于预后癌症标志物，特别是黑素瘤预后标志物的方法，组合物，试剂盒和装置，以帮助癌症的预后和治疗。

    Method for cutting a continuous glass sheet during the production of flat glass
    7.
    发明授权
    Method for cutting a continuous glass sheet during the production of flat glass 有权
    在制造平板玻璃期间切割连续玻璃板的方法

    公开(公告)号：US08430289B2

    公开(公告)日：2013-04-30

    申请号：US13335177

    申请日：2011-12-22

    申请人： Thomas John ,  Andreas Morstein

    发明人： Thomas John ,  Andreas Morstein

    IPC分类号： B65H35/10

    CPC分类号： C03B33/0235 ,  Y10T83/0333 ,  Y10T83/0341 ,  Y10T83/0348 ,  Y10T225/10 ,  Y10T225/12 ,  Y10T225/16 ,  Y10T225/30

    摘要： In the method for cutting a continuously moving glass sheet with an inhomogeneous thickness distribution across the glass sheet, a cutting tool is moved across it at an angle to its travel direction to form a fissure and then the glass sheet is broken along the fissure. To avoid premature breakage in thin regions the applied cutting force is controlled by a controller based on control commands so that the cutting force is decreased when the glass sheet thickness decreases and is increased when it increases. In a preferred embodiment cutting force switchover points are based on an initial measurement of the thickness distribution. In another embodiment the thickness is continuously measured and the applied cutting force is automatically adjusted accordingly, so that the cutting force is greater when the thickness is greater, and vice versa.

    摘要翻译： 在用于切割玻璃板上具有不均匀厚度分布的连续移动的玻璃板的方法中，切割工具以与其行进方向成一定角度的方式移动，以形成裂缝，然后沿着裂缝破碎玻璃板。 为了避免在薄区域过早断裂，所施加的切削力由控制器基于控制命令控制，使得当玻璃板厚度减小时切削力降低，并且当其增加时其增加。 在优选实施例中，切割力切换点基于厚度分布的初始测量。 在另一个实施例中，连续地测量厚度并相应地自动调整所施加的切削力，使得当厚度较大时切削力更大，反之亦然。

    CONTROLLABLE SIGN FOR USE WITH ALTERNATE SIDE STREET PARKING
    9.
    发明申请
    CONTROLLABLE SIGN FOR USE WITH ALTERNATE SIDE STREET PARKING 审中-公开
    可控制的标志用于与另外的街道停放

    公开(公告)号：US20110199235A1

    公开(公告)日：2011-08-18

    申请号：US12888649

    申请日：2010-09-23

    申请人： Thomas John

    发明人： Thomas John

    IPC分类号： B60Q1/48

    CPC分类号： G08G1/14 ,  G08G1/142 ,  G08G1/147 ,  G08G1/149

    摘要： A method for dynamically changing information conveyed by a street sign to alert drivers that parking is permitted as a result of an official vehicle approaching and/or passing the sign and transmitting a control signal to cause updating of the sign.

    摘要翻译： 一种用于动态地改变由路牌传达的信息的方法，以警告驾驶员由于官方车辆接近和/或传递标志而允许停车，并发送控制信号以引起符号的更新。

    SECURITY SYSTEM FOR USE IN HIRED VEHICLES
    10.
    发明申请
    SECURITY SYSTEM FOR USE IN HIRED VEHICLES 审中-公开
    有用的车辆使用安全系统

    公开(公告)号：US20110058039A1

    公开(公告)日：2011-03-10

    申请号：US12859044

    申请日：2010-08-18

    申请人： Thomas John

    发明人： Thomas John

    IPC分类号： H04N7/18

    CPC分类号： B60R11/04 ,  G07C5/008 ,  G07C5/085 ,  G07C5/0866 ,  G07C5/0891

    摘要： In accordance with one embodiment, a security system is provided on the vehicle that captures and stores the image (face) of the customer but also documents, using a GPS system, the entry (start) point and the exit (end) point of the ride. All this information can be stored locally and transmitted wirelessly to a remote central database where it is stored and can later be accessed.

    摘要翻译： 根据一个实施例，在车辆上提供了一种安全系统，其捕获并存储顾客的图像（面部），而且还使用GPS系统记录文件的开始点（起点）和出口（终点） 骑。 所有这些信息可以在本地存储，并以无线方式传输到远程中央数据库，在那里存储并可以随后访问。