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1.发明申请公开(公告)号：US20050255092A1
公开(公告)日：2005-11-17
申请号：US11129767
申请日：2005-05-13
CPC分类号： A61K35/742 , A23K10/18 , A23K50/30 , C12R1/07 , A61K2300/00
摘要： Bacillus strains that inhibit pathogenic swine E. coli and/or improve performance are provided. Inhibition of pathogenic swine E. coli decreases E. coli disease. At least one strain enhanced swine performance by improving average daily gain, feed efficiency, and feed intake. Preferred Bacillus strains are of species that are included on the GRAS list. Bacillus species are sporeformers and therefore are highly stable and can be fed to swine.
摘要翻译： 提供了抑制致病性猪大肠杆菌和/或改善性能的芽孢杆菌菌株。 致病性猪大肠杆菌的抑制减少大肠杆菌病。 至少一种通过提高平均日增重，饲料效率和饲料摄入量来提高猪的表现。 优选的芽孢杆菌菌株是GRAS列表中包含的物种。 芽孢杆菌种是孢子形成物，因此是高度稳定的，可以喂给猪。
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公开(公告)号：US20130295067A1
公开(公告)日：2013-11-07
申请号：US13887792
申请日：2013-05-06
申请人： Tammy Baltzley , Firmin Lago , Tony Neumann , Thomas Rehberger , Shelly Gebert
发明人： Tammy Baltzley , Firmin Lago , Tony Neumann , Thomas Rehberger , Shelly Gebert
CPC分类号： C12N1/20 , A61K35/742 , C12R1/07
摘要： An isolated Bacillus strain LSSAO1 is provided. When fed to a bird, this and other Bacillus strains described herein provide benefits to the birds. For example, administration of the one or more Bacillus strain can increase low G+C, gram positive bacteria in the gastrointestinal flora of the bird. These type of bacteria are increased by antibiotics and include beneficial Clostridium. Administration of the one or more Bacillus strain can also inhibit pathogen in the bird, such as E. coli, Salmonella, and Clostridium. These benefits can enhance feed conversion in poultry. Useful combinations of Bacillus strains and methods of using one or more Bacillus strain are also provided.
摘要翻译： 提供了分离的芽孢杆菌菌株LSSAO1。 当喂养鸟类时，本文所述的这种和其它芽孢杆菌菌株对鸟类有益。 例如，一种或多种芽孢杆菌菌株的施用可以增加鸟的胃肠道菌群中的低G + C，革兰氏阳性细菌。 这些类型的细菌通过抗生素增加并且包括有益的梭菌。 一种或多种芽孢杆菌菌株的施用也可以抑制鸟类中的病原体，例如大肠杆菌，沙门氏菌和梭菌属。 这些益处可以提高家禽饲料转化率。 还提供了芽孢杆菌菌株的有用组合和使用一种或多种芽孢杆菌菌株的方法。
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公开(公告)号：US20070202088A1
公开(公告)日：2007-08-30
申请号：US11565474
申请日：2006-11-30
申请人： Tammy Baltzley , Firmin Lago , Tony Neumann , Thomas Rehberger , Shelly Gebert
发明人： Tammy Baltzley , Firmin Lago , Tony Neumann , Thomas Rehberger , Shelly Gebert
CPC分类号： C12N1/20 , A61K35/742 , C12R1/07
摘要： An isolated Bacillus strain LSSAO1 is provided. When fed to a bird, this and other Bacillus strains described herein provide benefits to the birds. For example, administration of the one or more Bacillus strain can increase low G+C, gram positive bacteria in the gastrointestinal flora of the bird. These type of bacteria are increased by antibiotics and include beneficial Clostridium. Administration of the one or more Bacillus strain can also inhibit pathogen in the bird, such as E. coli, Salmonella, and Clostridium. These benefits can enhance feed conversion in poultry. Useful combinations of Bacillus strains and methods of using one or more Bacillus strain are also provided.
摘要翻译： 提供了分离的芽孢杆菌菌株LSSAO1。 当喂养鸟类时，本文所述的这种和其它芽孢杆菌菌株对鸟类有益。 例如，一种或多种芽孢杆菌菌株的施用可以增加鸟的胃肠道菌群中的低G + C，革兰氏阳性细菌。 这些类型的细菌通过抗生素增加并且包括有益的梭菌。 一种或多种芽孢杆菌菌株的施用也可以抑制鸟类中的病原体，例如大肠杆菌，沙门氏菌和梭菌属。 这些益处可以提高家禽饲料转化率。 还提供了芽孢杆菌菌株的有用组合和使用一种或多种芽孢杆菌菌株的方法。
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公开(公告)号：US06887489B2
公开(公告)日：2005-05-03
申请号：US10209735
申请日：2002-08-01
IPC分类号： A23K1/00 , A23K1/18 , A61K35/74 , A61K35/744 , A61K35/745 , A61K35/747 , A61K45/00
CPC分类号： A61K35/747 , A23K10/18 , A23K50/00 , A23K50/10 , A23K50/30 , A23Y2320/00 , A61K35/74 , A61K35/744 , A61K35/745 , Y10S426/807
摘要： A ruminant direct fed microbial composition of matter comprising an acidosis inhibiting effective amount of Propionibacterium P-63 is provided. Also disclosed is a process for reducing acidosis in ruminants or scours in swine by administration of the bacterium to the ruminant or swine. The microbial composition may be administered by itself, or combined with animal feed and/or lactic acid producing cultures.
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公开(公告)号：US20050002921A1
公开(公告)日：2005-01-06
申请号：US10874777
申请日：2004-06-23
CPC分类号： A61K35/747 , A23K10/18 , A23K50/60 , Y10S426/807 , Y10S435/855 , A61K2300/00
摘要： A composition comprising lactic acid bacteria that are selected from at least one of Lactococcus lactis, Lactobacillus lactis, and Lactobacillus brevis. The composition is suitable for administration to animals. Upon administration to an animal, the composition provides at least one of the following (a) improves performance in the animal and (b) reduces scours in animals. Also provided is a method of treating an animal in which the composition is administered to the animal. A method of forming a direct-fed microbial is also provided. A culture including the lactic acid bacteria is grown in a liquid nutrient broth. The lactic acid bacteria are separated from the liquid nutrient broth. The lactic acid bacteria can be freeze dried.
摘要翻译： 一种组合物，其包含选自乳酸乳球菌，乳酸乳杆菌和短乳杆菌中的至少一种的乳酸菌。 该组合物适用于给予动物。 在给予动物时，组合物提供以下至少一种（a）改善动物的性能，和（b）减少动物的冲洗。 还提供了一种治疗其中向动物施用组合物的动物的方法。 还提供了形成直接进料的微生物的方法。 包含乳酸菌的培养物在液体营养肉汤中生长。 从液体营养液中分离乳酸菌。 乳酸菌可以冷冻干燥。
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公开(公告)号：US08021654B2
公开(公告)日：2011-09-20
申请号：US12404149
申请日：2009-03-13
申请人： Thomas Rehberger , Mari Ellen Davis , Ashley Baker
发明人： Thomas Rehberger , Mari Ellen Davis , Ashley Baker
IPC分类号： A01N63/00
CPC分类号： A61K35/74 , A23K10/18 , A23K50/10 , A23K50/30 , A61K2035/11
摘要： Disclosed are methods of administering at least two Bacillus strains to a pig, such as female breeding stock, nursery pigs, or other pigs. The Bacillus strains inhibit Clostridium in litters borne to the pig. The Bacillus strains also are useful when administered to herds lacking symptoms of Clostridium infection. Administration of the Bacillus strains improves performance of female breeding stock and in piglets borne by the female breeding stock.
摘要翻译： 公开了将至少两种芽孢杆菌菌株施用于猪的方法，例如雌性育种种，育苗猪或其他猪。 芽孢杆菌菌株抑制猪的梭菌。 当对缺乏梭菌感染症状的群体施用时，芽孢杆菌菌株也是有用的。 芽孢杆菌菌株的施用提高了雌性育种种群和由雌性育种种群携带的仔猪的表现。
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7.发明申请Propionibacterium P-63 for use in direct fed microbials for animal feeds 审中-公开用于动物饲料的直接饲养微生物的丙酸杆菌P-63公开(公告)号：US20050214273A1
公开(公告)日：2005-09-29
申请号：US10995018
申请日：2004-11-22
申请人： Thomas Rehberger , Terry Parrott , Fred Owens , Charles Hibberd
发明人： Thomas Rehberger , Terry Parrott , Fred Owens , Charles Hibberd
IPC分类号： A23K1/00 , A23K1/18 , A61K35/74 , A61K35/744 , A61K35/745 , A61K35/747 , A61K45/00
CPC分类号： A61K35/747 , A23K10/18 , A23K50/00 , A23K50/10 , A23K50/30 , A23Y2320/00 , A61K35/74 , A61K35/744 , A61K35/745 , Y10S426/807
摘要： A ruminant direct fed microbial composition of matter comprising an acidosis inhibiting effective amount of Propionibacterium P-63 is provided. Also disclosed is a process for reducing acidosis in ruminants or scours in swine by administration of the bacterium to the ruminant or swine. The microbial composition may be administered by itself, or combined with animal feed and/or lactic acid producing cultures.
摘要翻译： 提供反刍动物直接饲养的微生物组合物，其包含抑制酸中毒的有效量的丙酸杆菌P-63。 还公开了通过向反刍动物或猪施用细菌来减少反刍动物中的酸中毒或猪的冲洗的方法。 微生物组合物可以自身施用，或与动物饲料和/或产生乳酸的培养物组合施用。
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公开(公告)号：US08563295B2
公开(公告)日：2013-10-22
申请号：US12685979
申请日：2010-01-12
IPC分类号： C12N1/20
CPC分类号： A61K35/744 , A23K10/18 , A23K50/30 , A23K50/60 , A61K35/12 , A61K35/747 , C07K14/335 , C12Q1/689 , C12Q2600/158 , C12R1/01
摘要： TRFs useful for identifying strains of interest are provided. A method of identifying one or more strain that can be used as a direct-fed microbial is also provided. One or more strain identified by the method is additionally provided. A method is also provided for administering to an animal an effective amount of the one or more strain. Additionally provided is an isolated strain chosen from at least one of Lactobacillus acidophilus strain PlB c6 (NRRL B-50103), Lactobacillus salivarius strain o246e 33w (NRRL B-50102), Pediococcus acidilactici strain o246e 42 (NRRL B-50171), and Pediococcus acidilactici strain PlJ e3 (NRRL B-50101). An isolated strain having all of the identifying characteristics of one of the strains listed above is also provided. One or more strain can be administered as a direct-fed microbial to an animal. Methods of preparing a direct-fed microbial are also provided.
摘要翻译： 提供了用于鉴定感兴趣菌株的TRF。 还提供了鉴定可用作直接饲养的微生物的一种或多种菌株的方法。 另外提供了通过该方法鉴定的一种或多种菌株。 还提供了一种给动物施用有效量的一种或多种菌株的方法。 另外提供了选自嗜酸乳杆菌菌株PlB c6（NRRL B-50103），唾液乳杆菌菌株o246e 33w（NRRL B-50102），乳酸杆菌菌株o246e 42（NRRL B-50171）和鳞状球菌中的至少一种的分离菌株 酸性菌株PlJ e3（NRRL B-50101）。 还提供了具有上述一种菌株的所有鉴定特征的分离菌株。 一种或多种菌株可以作为直接饲养的微生物施用于动物。 还提供了制备直接饲养的微生物的方法。
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公开(公告)号：US20120100118A1
公开(公告)日：2012-04-26
申请号：US13212409
申请日：2011-08-18
申请人： Thomas Rehberger , Mari Ellen Davis , Ashley Baker
发明人： Thomas Rehberger , Mari Ellen Davis , Ashley Baker
CPC分类号： A61K35/74 , A23K10/18 , A23K50/10 , A23K50/30 , A61K2035/11
摘要： Disclosed are methods of administering at least two Bacillus strains to a pig, such as female breeding stock, nursery pigs, or other pigs. The Bacillus strains inhibit Clostridium in litters borne to the pig. The Bacillus strains also are useful when administered to herds lacking symptoms of Clostridium infection. Administration of the Bacillus strains improves performance of female breeding stock and in piglets borne by the female breeding stock.
摘要翻译： 公开了将至少两种芽孢杆菌菌株施用于猪的方法，例如雌性育种种，育苗猪或其他猪。 芽孢杆菌菌株抑制猪的梭菌。 当对缺乏梭菌感染症状的群体施用时，芽孢杆菌菌株也是有用的。 芽孢杆菌菌株的施用提高了雌性育种种群和由雌性育种种群携带的仔猪的表现。
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公开(公告)号：US20100284981A1
公开(公告)日：2010-11-11
申请号：US12829013
申请日：2010-07-01
申请人： Tammy Baltzley , Firmin Lago , Tony Neumann , Thomas Rehberger , Shelly Gebert
发明人： Tammy Baltzley , Firmin Lago , Tony Neumann , Thomas Rehberger , Shelly Gebert
CPC分类号： C12N1/20 , A61K35/742 , C12R1/07
摘要： An isolated Bacillus strain LSSAO1 is provided. When fed to a bird, this and other Bacillus strains described herein provide benefits to the birds. For example, administration of the one or more Bacillus strain can increase low G+C, gram positive bacteria in the gastrointestinal flora of the bird. These type of bacteria are increased by antibiotics and include beneficial Clostridium. Administration of the one or more Bacillus strain can also inhibit pathogen in the bird, such as E. coli, Salmonella, and Clostridium. These benefits can enhance feed conversion in poultry. Useful combinations of Bacillus strains and methods of using one or more Bacillus strain are also provided.
摘要翻译： 提供了分离的芽孢杆菌菌株LSSAO1。 当喂养鸟类时，本文所述的这种和其它芽孢杆菌菌株对鸟类有益。 例如，一种或多种芽孢杆菌菌株的施用可以增加鸟的胃肠道菌群中的低G + C，革兰氏阳性细菌。 这些类型的细菌通过抗生素增加并且包括有益的梭菌。 一种或多种芽孢杆菌菌株的施用也可以抑制鸟类中的病原体，例如大肠杆菌，沙门氏菌和梭菌属。 这些益处可以提高家禽饲料转化率。 还提供了芽孢杆菌菌株的有用组合和使用一种或多种芽孢杆菌菌株的方法。
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