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公开(公告)号：US07072046B2
公开(公告)日：2006-07-04
申请号：US10633832
申请日：2003-08-04
申请人： Tianyu Xie , Akio Uchiyama , Atsushi Okawa
发明人： Tianyu Xie , Akio Uchiyama , Atsushi Okawa
IPC分类号： G01B9/02
CPC分类号： A61B5/6852 , A61B5/0066 , A61B2562/08
摘要： An attachment 10 that is proximal to an optical probe 9 includes probe information holding means 39 that holds probe information such as a scanning technique and an optical path length or the like. When the optical probe 9 is connected (attached) to an observing device 6, probe information detecting means included in the observing device 6 automatically detects the probe information held in the optical probe. Based on the detected probe information, a scanning technique and an optical path length of reference light are set to values suitable to an actually connected optical probe 9.
摘要翻译： 靠近光学探针9的附件10包括保持诸如扫描技术和光程长度等的探测信息的探测器信息保持装置39。 当光学探头9连接（附接）到观察装置6上时，观察装置6中包括的探测信息检测装置自动检测保持在光学探针中的探测信息。 基于检测到的探测信息，将参考光的扫描技术和光程长度设置为适合于实际连接的光学探针9的值。
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公开(公告)号：US08131349B2
公开(公告)日：2012-03-06
申请号：US11805228
申请日：2007-05-22
IPC分类号： A61B8/00
CPC分类号： A61B5/0071 , A61B1/00096 , A61B1/00188 , A61B1/043 , A61B1/0638 , A61B1/07 , A61B5/0084
摘要： A lesion extracting device having a control unit for changing an amount of the excitation light emitted toward a subject body, a measuring unit for measuring a change in the intensity of fluorescence generated from the subject body with respect to a change in the amount of the excitation light, and an extracting unit for calculating a ratio of the change in the intensity of fluorescence on the basis of a ratio of the change in the amount of the excitation light to the change in the intensity of fluorescence and for extracting a lesion part of the subject body on the basis of the ratio of the changes in the amount of the excitation light to the ratio of the changes in the intensity of fluorescence.
摘要翻译： 一种病变提取装置，具有用于改变朝向被检体发射的激发光的量的控制单元，测量单元，用于测量从被检体发出的荧光的强度相对于激发量的变化的变化 光和提取单元，用于基于激发光的量的变化与荧光强度的变化的比率和用于提取荧光强度的变化的比例来计算荧光强度的变化的比率 基于激发光量的变化与荧光强度的变化率的比率的对象体。
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公开(公告)号：US07129473B2
公开(公告)日：2006-10-31
申请号：US10846967
申请日：2004-05-14
申请人： Yasushige Ishihara , Atsushi Okawa , Hiroshi Tosaka , Tianyu Xie , Tadashi Hirata , Akihiro Horii , Kazunari Tokuda
发明人： Yasushige Ishihara , Atsushi Okawa , Hiroshi Tosaka , Tianyu Xie , Tadashi Hirata , Akihiro Horii , Kazunari Tokuda
CPC分类号： A61B1/04 , A61B1/0008 , A61B1/00096 , A61B1/00165 , A61B1/00172 , A61B1/00183 , A61B1/00188 , A61B1/07 , G02B21/0032 , G02B21/0036
摘要： A control portion of an optical image pickup apparatus includes a scan driver, a lock-in amplifier, and an A/D converter. The scan driver outputs a predetermined drive signal to a Y-scanning mirror and an X-scanning mirror and scans the Y-scanning mirror and the X-scanning mirror. The lock-in amplifier detects a signal level Vout of a frequency component of the drive signal of the scan driver among signals detected by a detector portion. The A/D converter converts a signal detected by a detector portion and a signal level of the detected signal of a frequency component of a drive signal detected by the lock-in amplifier to digital signals and outputs the digital signals to an image processor. Thus, mirror scan operations of the scanning mirrors can be securely detected.
摘要翻译： 光学摄像装置的控制部分包括扫描驱动器，锁定放大器和A / D转换器。 扫描驱动器向Y扫描镜和X扫描镜输出预定的驱动信号，扫描Y扫描镜和X扫描镜。 锁定放大器在由检测器部分检测的信号中检测扫描驱动器的驱动信号的频率分量的信号电平Vout。 A / D转换器将由检测器部分检测的信号和由锁定放大器检测的驱动信号的频率分量的检测信号的信号电平转换为数字信号，并将数字信号输出到图像处理器。 因此，可以可靠地检测扫描镜的镜像扫描操作。
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4.发明授权公开(公告)号：US07966051B2
公开(公告)日：2011-06-21
申请号：US11327866
申请日：2006-01-09
申请人： Tianyu Xie , Atsushi Okawa
发明人： Tianyu Xie , Atsushi Okawa
CPC分类号： A61M5/1723 , A61M5/16836 , A61M2005/1726 , A61M2205/3306 , G01N21/645 , G01N21/6486
摘要： A fluorescent agent accumulation concentration measuring apparatus is configured to include a single-wavelength LED to radiate excitation light to a test bottle loaded in the inside, a barrier filter to transmit only fluorescence from the test bottle, a photoreceptor to receive the fluorescence through the barrier filter and output an electric signal, a detection processing circuit to conduct signal processing of the electric signal from the photoreceptor and detect the fluorescence intensity, and an operation circuit 26 to compare the detection result from the detection processing circuit with an analytical pattern stored in a pattern storage portion and calculate the peak time of the accumulation concentration in a tissue of a sample in the test bottle.
摘要翻译： 荧光剂蓄积浓度测量装置被配置为包括单波长LED以将激发光辐射到装在内部的测试瓶中，阻挡滤光器仅透射来自测试瓶的荧光，感光体以通过屏障接收荧光 滤波并输出电信号，检测处理电路，对来自感光体的电信号进行信号处理，检测荧光强度;以及运算电路26，将来自检测处理电路的检测结果与存储在 模式存储部分，并计算试验瓶中样品的组织中的累积浓度的峰值时间。
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公开(公告)号：US20060188402A1
公开(公告)日：2006-08-24
申请号：US11327866
申请日：2006-01-09
申请人： Tianyu Xie , Atsushi Okawa
发明人： Tianyu Xie , Atsushi Okawa
IPC分类号： G01N21/64
CPC分类号： A61M5/1723 , A61M5/16836 , A61M2005/1726 , A61M2205/3306 , G01N21/645 , G01N21/6486
摘要： A fluorescent agent accumulation concentration measuring apparatus is configured to include a single-wavelength LED to radiate excitation light to a test bottle loaded in the inside, a barrier filter to transmit only fluorescence from the test bottle, a photoreceptor to receive the fluorescence through the barrier filter and output an electric signal, a detection processing circuit to conduct signal processing of the electric signal from the photoreceptor and detect the fluorescence intensity, and an operation circuit 26 to compare the detection result from the detection processing circuit with an analytical pattern stored in a pattern storage portion and calculate the peak time of the accumulation concentration in a tissue of a sample in the test bottle.
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公开(公告)号：US08521261B2
公开(公告)日：2013-08-27
申请号：US13359671
申请日：2012-01-27
IPC分类号： A61B5/05
CPC分类号： A61B5/0071 , A61B1/00096 , A61B1/00188 , A61B1/043 , A61B1/0638 , A61B1/07 , A61B5/0084
摘要： A lesion extracting device includes a light source for emitting an excitation light toward a subject body, a control unit for changing an amount of the excitation light, a light irradiating and receiving portion for irradiating the excitation light to the subject body and receiving fluorescence generated from the subject body, a distance holding member for holding a distance between the subject body and the light irradiating and receiving portion at a predetermined value, a measuring unit for measuring the intensity of the fluorescence received by the light irradiating and receiving portion, and an extracting unit for extracting a lesion part of the subject body based on relationships between measured values of changes in the fluorescence intensity with respect to changes in the amount of the excitation light and information regarding the changes in the amount of the excitation light, the information being obtained from the control unit.
摘要翻译： 病变提取装置包括用于向受检者体发射激发光的光源，用于改变激发光量的控制单元，用于将激发光照射到被摄体的光照射和接收部分，并接收从 被检体，用于将被检体与受光部之间的距离保持在预定值的距离保持构件，用于测量由光照射和接收部接收的荧光强度的测量单元， 基于与激发光量的变化相关的荧光强度的变化的测量值与激发光量的变化的信息之间的关系来提取被检体的病变部的单元，获得的信息 从控制单元。
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公开(公告)号：US20060261263A1
公开(公告)日：2006-11-23
申请号：US11494184
申请日：2006-07-27
申请人： Yasushige Ishihara , Atsushi Okawa , Hiroshi Tosaka , Tianyu Xie , Tadashi Hirata , Akihiro Horii , Kazunari Tokuda
发明人： Yasushige Ishihara , Atsushi Okawa , Hiroshi Tosaka , Tianyu Xie , Tadashi Hirata , Akihiro Horii , Kazunari Tokuda
CPC分类号： A61B1/04 , A61B1/0008 , A61B1/00096 , A61B1/00165 , A61B1/00172 , A61B1/00183 , A61B1/00188 , A61B1/07 , G02B21/0032 , G02B21/0036
摘要： A control portion of an optical image pickup apparatus includes a scan driver, a lock-in amplifier, and an A/D converter. The scan driver outputs a predetermined drive signal to a Y-scanning mirror and an X-scanning mirror and scans the Y-scanning mirror and the X-scanning mirror. The lock-in amplifier detects a signal level Vout of a frequency component of the drive signal of the scan driver among signals detected by a detector portion. The A/D converter converts a signal detected by a detector portion and a signal level of the detected signal of a frequency component of a drive signal detected by the lock-in amplifier to digital signals and outputs the digital signals to an image processor. Thus, mirror scan operations of the scanning mirrors can be securely detected.
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公开(公告)号：US20120197134A1
公开(公告)日：2012-08-02
申请号：US13359671
申请日：2012-01-27
CPC分类号： A61B5/0071 , A61B1/00096 , A61B1/00188 , A61B1/043 , A61B1/0638 , A61B1/07 , A61B5/0084
摘要： A lesion extracting device includes a light source for emitting an excitation light toward a subject body, a control unit for changing an amount of the excitation light, a light irradiating and receiving portion for irradiating the excitation light to the subject body and receiving fluorescence generated from the subject body, a distance holding member for holding a distance between the subject body and the light irradiating and receiving portion at a predetermined value, a measuring unit for measuring the intensity of the fluorescence received by the light irradiating and receiving portion, and an extracting unit for extracting a lesion part of the subject body based on relationships between measured values of changes in the fluorescence intensity with respect to changes in the amount of the excitation light and information regarding the changes in the amount of the excitation light, the information being obtained from the control unit.
摘要翻译： 病变提取装置包括用于向受检者体发射激发光的光源，用于改变激发光量的控制单元，用于将激发光照射到被摄体的光照射和接收部分，并接收从 被检体，用于将被检体与受光部之间的距离保持在预定值的距离保持构件，用于测量由光照射和接收部接收的荧光强度的测量单元， 基于与激发光量的变化相关的荧光强度的变化的测量值与激发光量的变化的信息之间的关系来提取被检体的病变部的单元，获得的信息 从控制单元。
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公开(公告)号：US08123679B2
公开(公告)日：2012-02-28
申请号：US11897848
申请日：2007-08-31
IPC分类号： A61B1/06
CPC分类号： A61B1/042 , A61B1/00154 , A61B1/00163 , A61B1/00165 , A61B1/00177 , A61B1/0615 , A61B1/07 , A61B5/064
摘要： The invention includes an insertion portion, one end of which is inserted inside a lumen of a subject; an image-acquisition unit for acquiring an image of an interior wall in the lumen as a substantially circular or substantially ring-shaped interior wall image; a transformation processing unit for transforming, in the interior wall image, at least substantially ring-shaped images concerning the interior wall, whose distance from the one end is uniform, to substantially straight-line-shaped or substantially band-shaped images; a distance-measuring unit for measuring a distance moved by the insertion portion relative to the subject; and an image synthesizing unit for joining the transformed images on the basis of the distance moved measured by the distance-measuring unit.
摘要翻译： 本发明包括一个插入部分，其一端插入被检体内腔内; 图像获取单元，用于获取内腔中的内壁的图像为大致圆形或大致环形的内壁图像; 变换处理单元，用于在内壁图像中转换至少基本上呈直线状或基本上带状的图像的关于内壁的距离为一体的内壁的环形图像; 距离测量单元，用于测量由插入部分相对于被摄体移动的距离; 以及图像合成单元，用于基于由距离测量单元测量的移动距离来连接变换图像。
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公开(公告)号：US07427747B2
公开(公告)日：2008-09-23
申请号：US11494184
申请日：2006-07-27
申请人： Yasushige Ishihara , Atsushi Okawa , Hiroshi Tosaka , Tianyu Xie , Tadashi Hirata , Akihiro Horii , Kazunari Tokuda
发明人： Yasushige Ishihara , Atsushi Okawa , Hiroshi Tosaka , Tianyu Xie , Tadashi Hirata , Akihiro Horii , Kazunari Tokuda
CPC分类号： A61B1/04 , A61B1/0008 , A61B1/00096 , A61B1/00165 , A61B1/00172 , A61B1/00183 , A61B1/00188 , A61B1/07 , G02B21/0032 , G02B21/0036
摘要： A control portion of an optical image pickup apparatus includes a scan driver, a lock-in amplifier, and an A/D converter. The scan driver outputs a predetermined drive signal to a Y-scanning mirror and an X-scanning mirror and scans the Y-scanning mirror and the X-scanning mirror. The lock-in amplifier detects a signal level Vout of a frequency component of the drive signal of the scan driver among signals detected by a detector portion. The A/D converter converts a signal detected by a detector portion and a signal level of the detected signal of a frequency component of a drive signal detected by the lock-in amplifier to digital signals and outputs the digital signals to an image processor. Thus, mirror scan operations of the scanning mirrors can be securely detected.
摘要翻译： 光学摄像装置的控制部分包括扫描驱动器，锁定放大器和A / D转换器。 扫描驱动器向Y扫描镜和X扫描镜输出预定的驱动信号，扫描Y扫描镜和X扫描镜。 锁定放大器在由检测器部分检测的信号中检测扫描驱动器的驱动信号的频率分量的信号电平Vout。 A / D转换器将由检测器部分检测的信号和由锁定放大器检测的驱动信号的频率分量的检测信号的信号电平转换为数字信号，并将数字信号输出到图像处理器。 因此，可以可靠地检测扫描镜的镜像扫描操作。
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