GENE CLUSTER FOR BIOSYNTHESIS OF CYCLOCLAVINE
    3.
    发明申请
    GENE CLUSTER FOR BIOSYNTHESIS OF CYCLOCLAVINE 审中-公开
    CYCLOCLAVINE生物化学基因组

    公开(公告)号:US20140073008A1

    公开(公告)日:2014-03-13

    申请号:US14000080

    申请日:2012-02-24

    IPC分类号: C12P17/18

    摘要: The invention in principle pertains to the field of recombinant manufacture of alkaloids and, in particular, cycloclavine. It provides polynucleotides for the gene cluster of enzymes involved in the biosynthesis of cycloclavin as well as vectors and host cells comprising such polynucleotides. Also provided are polypeptides encoded by the said polynucleotides which can be applied in a method for the manufacture of cycloclavine also encompassed by the present invention.

    摘要翻译: 本发明原则上涉及生物碱重组生产领域,特别是环己烯环素。 它提供参与环烯克蛋白生物合成的酶的基因簇的多核苷酸以及包含这种多核苷酸的载体和宿主细胞。 还提供了由所述多核苷酸编码的多肽,其可以用于制备本发明也包括的环己烯环的方法。