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1.发明申请Probiotics in the treatment of atypical depression and other disorders characterised by hypothalamic pitiuitary-ardrenal axis over activity 审中-公开益生菌治疗非典型性抑郁症等特征性下丘脑垂体 - 肾上腺轴超过活动公开(公告)号：US20060204485A1
公开(公告)日：2006-09-14
申请号：US11434002
申请日：2006-05-15
申请人： Timothy Dinan , Liam O'Mahony , Barry Kiely , Eamonn Quigley , Fergus Shanahan , John Collins
发明人： Timothy Dinan , Liam O'Mahony , Barry Kiely , Eamonn Quigley , Fergus Shanahan , John Collins
IPC分类号： A61K35/74
CPC分类号： C12R1/225 , A61K35/745 , A61K35/747 , C12R1/01
摘要： A method of treating a disorder characterized by hypothalamic-pituitary-adrenal axis over-activity comprising administering to a subject a probiotic bacterium.
摘要翻译： 一种治疗以下丘脑 - 垂体 - 肾上腺轴过度活性为特征的疾病的方法，其包括对受试者施用益生菌。
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公开(公告)号：US20060088514A1
公开(公告)日：2006-04-27
申请号：US11238092
申请日：2005-09-29
申请人： Liam O'Mahony , Fergus Shanahan , Barry Kiely , John Collins , Gerald O'Sullivan
发明人： Liam O'Mahony , Fergus Shanahan , Barry Kiely , John Collins , Gerald O'Sullivan
IPC分类号： A61K35/74
CPC分类号： A61K35/747 , A61K9/0019 , A61K39/07 , A61K47/02
摘要： An injectable formulation of a bacterial strain such as a Lactobacillus salivarius strain is useful in treating of inflammatory disorders such as colitis or arthritis.
摘要翻译： 细菌菌株例如唾液乳杆菌菌株的可注射制剂可用于治疗炎症性疾病如结肠炎或关节炎。
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公开(公告)号：US20060121015A1
公开(公告)日：2006-06-08
申请号：US11149195
申请日：2005-06-10
申请人： John Collins , Gerald O'Sullivan , Liam O'Mahony , Fergus Shanahan , Barry Kiely
发明人： John Collins , Gerald O'Sullivan , Liam O'Mahony , Fergus Shanahan , Barry Kiely
CPC分类号： C12N1/20 , A23L33/135 , A23Y2300/00 , A23Y2300/55 , A61K35/745 , C12R1/02
摘要： A Bifidobacterium strain, AH208, AH209, AH210, AH211, AH212 or AH214 or mutants or variants thereof are useful in the prophylaxis and/or treatment of inflammatory activity especially undesirable gastrointestinal inflammatory activity, such as inflammatory bowel disease or irritable bowel syndrome.
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公开(公告)号：US20060078547A1
公开(公告)日：2006-04-13
申请号：US11105590
申请日：2005-04-14
申请人： John Collins , Gerald O'Sullivan , Liam O'Mahony , Fergus Shanahan , Barry Kiely
发明人： John Collins , Gerald O'Sullivan , Liam O'Mahony , Fergus Shanahan , Barry Kiely
CPC分类号： A61K35/747 , A23L33/135 , A23Y2220/79 , C12N1/20 , C12R1/225
摘要： A Lactobacillus salivarius strain, AH102, AH103, AH105, AH109 or AH110 or mutants or variants thereof are useful in the prophylaxis and/or treatment of inflammatory activity especially undesirable gastrointestinal inflammatory activity, such as inflammatory bowel disease or irritable bowel syndrome.
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5.发明申请Modulation of Tissue Fatty Acid Composition of a Host by Human Gut Bacteria 审中-公开通过人肠细菌调节宿主的组织脂肪酸组成公开(公告)号：US20100284979A1
公开(公告)日：2010-11-11
申请号：US12681045
申请日：2008-09-30
申请人： Liam O'Mahony , Fergus Shanahan , Eamonn Quigley , Paul Ross , Catherine Stanton
发明人： Liam O'Mahony , Fergus Shanahan , Eamonn Quigley , Paul Ross , Catherine Stanton
CPC分类号： C12N1/20 , A23L33/135 , A61K31/201 , A61K35/74 , A61K35/744 , A61K35/745 , A61K35/747 , C12P7/6427 , C12P7/6472 , C12R1/01
摘要： The current invention provides use of a CLA-producing bacterium for the in vivo conversion in the gut of polyunsaturated fatty acids to CLA. The CLA-producing bacterium is selected from one or more of the group consisting of propionibacteria, lactobacilli, lactococci and streptococci, and bifidobacteria.
摘要翻译： 本发明提供了使CLA产生细菌用于多不饱和脂肪酸肠内体内转化成CLA的用途。 产生CLA的细菌选自丙酸杆菌属，乳杆菌属，乳球菌属和链球菌属中的一种或多种，以及双歧杆菌。
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公开(公告)号：US07390519B2
公开(公告)日：2008-06-24
申请号：US11105590
申请日：2005-04-14
申请人： John Kevin Collins , Gerald Christopher O'Sullivan , Liam O'Mahony , Fergus Shanahan , Barry Kiely
发明人： John Kevin Collins , Gerald Christopher O'Sullivan , Liam O'Mahony , Fergus Shanahan , Barry Kiely
CPC分类号： A61K35/747 , A23L33/135 , A23Y2220/79 , C12N1/20 , C12R1/225
摘要： A Lactobacillus salivarius strain, AH102, AH103, AH105, AH109 or AH110 or mutants or variants thereof are useful in the prophylaxis and/or treatment of inflammatory activity especially undesirable gastrointestinal inflammatory activity, such as inflammatory bowel disease or irritable bowel syndrome.
摘要翻译： A唾液乳杆菌菌株AH102，AH103，AH105，AH109或AH110或其突变体或变体可用于预防和/或治疗炎性活动，特别是不期望的胃肠炎症活动，例如炎性肠病或肠易激综合征。
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公开(公告)号：US20060002908A1
公开(公告)日：2006-01-05
申请号：US10975353
申请日：2004-10-29
CPC分类号： C12R1/01 , A23C9/1234 , A23L33/135 , A23V2002/00 , A23Y2220/77 , A61K39/09 , A61K2039/52 , A61K2039/542 , C12N1/20 , Y10S435/822 , Y10S435/853 , A23V2200/3204 , A23V2200/324
摘要： A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatroy activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer.
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公开(公告)号：US20050084482A1
公开(公告)日：2005-04-21
申请号：US10804223
申请日：2004-03-19
IPC分类号： A23L1/30 , A23C9/123 , A61K9/14 , A61K9/20 , A61K9/48 , A61K39/00 , A61K47/02 , A61K47/04 , A61K47/06 , A61K47/08 , A61K47/18 , A61K47/26 , A61K47/42 , A61K47/44 , A61K47/46 , A61P1/00 , A61P1/04 , A61P1/12 , A61P19/02 , A61P29/00 , A61P31/04 , A61P31/12 , A61P35/00 , A61P37/04 , A61P37/06 , A61P43/00 , C12N1/20 , C12R1/01 , C12R1/225 , A61K45/00
CPC分类号： C12R1/01 , A23C9/1234 , A23L33/135 , A23V2002/00 , A23Y2220/77 , A61K39/09 , A61K2039/52 , A61K2039/542 , C12N1/20 , Y10S435/822 , Y10S435/853 , A23V2200/3204 , A23V2200/324
摘要： Lactobacillus salivarius is useful in the prophylaxis or treatment of undesirable inflammatory activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer. The Lactobacillus salivarius is of human origin isolated from resected and washed human gastrointestinal tract. One such strain is UCC 118 described in WO-A-9835014.
摘要翻译： 唾液乳杆菌可用于预防或治疗不希望的炎性活动，特别是胃肠炎症活动，如炎性肠病或肠易激综合征。 炎症活动也可能是由于癌症。 唾液乳杆菌是从切除和洗涤的人类胃肠道分离的人源。 一种这样的菌株是在WO-A-9835014中描述的UCC 118。
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公开(公告)号：US20050074441A1
公开(公告)日：2005-04-07
申请号：US10783020
申请日：2004-02-23
IPC分类号： A23L1/30 , A23C9/123 , A61K9/14 , A61K9/20 , A61K9/48 , A61K39/00 , A61K47/02 , A61K47/04 , A61K47/06 , A61K47/08 , A61K47/18 , A61K47/26 , A61K47/42 , A61K47/44 , A61K47/46 , A61P1/00 , A61P1/04 , A61P1/12 , A61P19/02 , A61P29/00 , A61P31/04 , A61P31/12 , A61P35/00 , A61P37/04 , A61P37/06 , A61P43/00 , C12N1/20 , C12R1/01 , C12R1/225 , A61K45/00
CPC分类号： C12R1/01 , A23C9/1234 , A23L33/135 , A23V2002/00 , A23Y2220/77 , A61K39/09 , A61K2039/52 , A61K2039/542 , C12N1/20 , Y10S435/822 , Y10S435/853 , A23V2200/3204 , A23V2200/324
摘要： A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatroy activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer.
摘要翻译： 从切除和洗涤的人类胃肠道分离的双歧杆菌菌株在人类口服消费后是显着的免疫调节。 该菌株可用于预防和/或治疗不期望的炎症活性，特别是胃肠炎症活动如炎性肠病或肠易激综合征。 炎症活动也可能是由于癌症。
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公开(公告)号：US20080057109A1
公开(公告)日：2008-03-06
申请号：US11699115
申请日：2007-01-29
CPC分类号： C12R1/01 , A23C9/1234 , A23L33/135 , A23V2002/00 , A23Y2220/77 , A61K39/09 , A61K2039/52 , A61K2039/542 , C12N1/20 , Y10S435/822 , Y10S435/853 , A23V2200/3204 , A23V2200/324
摘要： A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatory activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer.
摘要翻译： 从切除和洗涤的人类胃肠道分离的双歧杆菌菌株在人类口服消费后是显着的免疫调节。 该菌株可用于预防和/或治疗不期望的炎性活动，特别是胃肠道炎症活动，如炎性肠病或肠易激综合征。 炎症活动也可能是由于癌症。
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