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1.发明申请公开(公告)号：US20140081299A1
公开(公告)日：2014-03-20
申请号：US13622921
申请日：2012-09-19
CPC分类号： H01L21/62 , A61B17/320068 , A61B17/3211 , A61B2017/00526
摘要： An ultrasonic core including a longitudinally elongated, generally planar waveguide defining an aperture extending from a first side of the waveguide toward a medial plane of the waveguide, and having a transducer element sized and shaped so as to substantially conform to the size and shape of the aperture and to be at least partially embedded within the waveguide. In other aspects, an ultrasonic core including a longitudinally elongated, generally planar silicon waveguide having at least one transducer element secured thereto and a wedge-shaped acoustic horn including an inclined side surface, characterized in that the inclined side surface is oriented along the {1,1,1} crystallographic plane of the silicon material. Also, methods of manufacturing the respective ultrasonic cores and ultrasonic handpieces for an ultrasonic surgical instruments incorporating such cores.
摘要翻译： 一种超声波芯，包括纵向细长的大致平面的波导，其限定了从波导的第一侧朝向波导的中间平面延伸的孔，并且具有尺寸和形状的换能器元件，以便基本上符合波导的尺寸和形状 并且至少部分地嵌入在波导内。 在其它方面，一种超声波芯，其包括纵向细长的大致平面的硅波导，其具有固定到其上的至少一个换能器元件和包括倾斜侧表面的楔形声喇叭，其特征在于，所述倾斜侧表面沿着{1 ，1,1}晶体平面的硅材料。 此外，制造用于包括这种芯的超声外科器械的各个超声波芯和超声手机的方法。
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公开(公告)号：US20120165794A1
公开(公告)日：2012-06-28
申请号：US12976761
申请日：2010-12-22
申请人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James W. Voegele , Mark S. Zeiner , Mark D. Overmyer , Joseph B. Kraimer , Jeff Shimizu , Rocco Crivelli , Yanik Tardy , Thierry Utard , Juergen Burger , Toralf Bork , Martin Pfleiderer , Olivier Chossat
发明人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James W. Voegele , Mark S. Zeiner , Mark D. Overmyer , Joseph B. Kraimer , Jeff Shimizu , Rocco Crivelli , Yanik Tardy , Thierry Utard , Juergen Burger , Toralf Bork , Martin Pfleiderer , Olivier Chossat
IPC分类号： A61M31/00
CPC分类号： A61B1/041 , A61B1/00147 , A61F5/0013 , A61M31/002
摘要： Devices and related methods are provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, methods and devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as “catchers,” are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs.
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公开(公告)号：US09427580B2
公开(公告)日：2016-08-30
申请号：US13825459
申请日：2012-03-30
申请人： Toralf Bork , Rocco Crivelli , Mathilde Miguras , Martin Pfleiderer , Yanik Tardy , Jason L. Harris , Mark S. Ortiz , Alessandro Pastorelli , Michele D'Arcangelo
发明人： Toralf Bork , Rocco Crivelli , Mathilde Miguras , Martin Pfleiderer , Yanik Tardy , Jason L. Harris , Mark S. Ortiz , Alessandro Pastorelli , Michele D'Arcangelo
CPC分类号： A61N1/36007 , A61F5/0026 , A61F2005/0016 , A61F2005/002 , A61N1/0509 , A61N1/0517
摘要： An implantable system for stimulating the release of satiety hormone in a subject comprises a stimulus device which is implantable in the subject and adapted to apply an electrical stimulus to a tissue of a gastrointestinal system of said subject, and a detection device which is implantable in the subject and adapted to continuously monitoring at least one of a mechanical characteristic and an electrical characteristic of the subject to detect an ingestion of food by said subject, wherein the detection device cooperates with the stimulus device such that the stimulus device applies said electrical stimulus in response to a detected ingestion of food.
摘要翻译： 用于刺激受试者中的饱腹感激素的释放的可植入系统包括刺激装置，该刺激装置可植入受试者并适于对所述受试者的胃肠系统的组织施加电刺激，以及可植入在所述受试者中的检测装置 受试者并且适于连续监测受试者的机械特征和电特性中的至少一个以检测所述受试者摄取食物，其中所述检测装置与刺激装置配合使得刺激装置应答所述电刺激 检测到摄入食物。
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公开(公告)号：US20150045850A1
公开(公告)日：2015-02-12
申请号：US13825459
申请日：2012-03-30
申请人： Toralf Bork , Rocco Crivelli , Mathilde Miguras , Martin Pfleiderer , Yanik Tardy , Jason L. Harris , Mark S. Ortiz , Alessandro Pastorelli , Michele D' Arcangelo
发明人： Toralf Bork , Rocco Crivelli , Mathilde Miguras , Martin Pfleiderer , Yanik Tardy , Jason L. Harris , Mark S. Ortiz , Alessandro Pastorelli , Michele D' Arcangelo
CPC分类号： A61N1/36007 , A61F5/0026 , A61F2005/0016 , A61F2005/002 , A61N1/0509 , A61N1/0517
摘要： An implantable system for stimulating the release of satiety hormone in a subject comprises a stimulus device (11) which is implantable in the subject and adapted to apply an electrical stimulus to a tissue of a gastrointestinal system of said subject, and a detection device which is implantable in the subject and adapted to continuously monitoring at least one of a mechanical characteristic and an electrical characteristic of the subject to detect an ingestion of food by said subject, wherein the detection device cooperates with the stimulus device (11) such that the stimulus device (11) applies said electrical stimulus in response to a detected ingestion of food.
摘要翻译： 用于刺激受试者中的饱腹感激素的释放的可植入系统包括刺激装置（11），其可植入对象中并适于对所述受试者的胃肠系统的组织施加电刺激，以及检测装置 可植入在受试者中并且适于连续地监测受试者的机械特性和电特性中的至少一个以检测所述受试者摄入的食物，其中检测装置与刺激装置（11）配合使得刺激装置 （11）响应于检测到的食物摄入而应用所述电刺激。
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公开(公告)号：US20060000270A1
公开(公告)日：2006-01-05
申请号：US10881425
申请日：2004-06-30
申请人： Frank Zumkehr , Juergen Burger , Toralf Bork , Alec Ginggen
发明人： Frank Zumkehr , Juergen Burger , Toralf Bork , Alec Ginggen
IPC分类号： G01F1/68
CPC分类号： A61B5/028 , G01F1/6845
摘要： A thermal flow sensor has a first substrate, second substrate and a third substrate, each of which has a first side and a second opposite side. The first substrate is connected to the second substrate such that the second side of the first substrate abuts the first side of the second substrate. The third substrate is connected to the second substrate such that the second side of the second substrate abuts the first side of the third substrate. The second substrate has a groove formed therein so as to form a conduit bounded by the second substrate and the second side of the first substrate and the first side of the third substrate. A heater is disposed on the first side of the first substrate opposed to the conduit. A first temperature sensor is disposed on the first side of the first substrate opposed to the conduit.
摘要翻译： 热流传感器具有第一基板，第二基板和第三基板，每个基板具有第一侧和第二相对侧。 第一基板连接到第二基板，使得第一基板的第二面邻接第二基板的第一侧。 第三基板连接到第二基板，使得第二基板的第二侧邻接第三基板的第一侧。 第二基板具有形成在其中的槽，以便形成由第二基板和第一基板的第二侧和第三基板的第一侧限定的导管。 加热器设置在与导管相对的第一基板的第一侧上。 第一温度传感器设置在与导管相对的第一基板的第一侧上。
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公开(公告)号：US20110040206A1
公开(公告)日：2011-02-17
申请号：US12853364
申请日：2010-08-10
申请人： Juergen Burger , Toralf Bork
发明人： Juergen Burger , Toralf Bork
CPC分类号： A61B5/6846 , A61B5/0031 , A61B5/031 , A61B5/032 , A61B2560/0223 , A61B2562/0247 , G01L19/02 , G01L27/002
摘要： A pressure sensor having a substrate and a first, deformable membrane, partially supported by the substrate, which generates a first sensor reading when deformed by pressure. A second membrane is contiguous to the first membrane. When the second membrane is energized, it deforms the first membrane to alter the first sensor reading.
摘要翻译： 一种压力传感器，其具有基板和由基板部分支撑的第一可变形膜，当通过压力变形时产生第一传感器读数。 第二个膜与第一个膜相邻。 当第二个膜通电时，它会使第一个膜变形，从而改变第一个传感器读数。
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公开(公告)号：US09131896B2
公开(公告)日：2015-09-15
申请号：US12853364
申请日：2010-08-10
申请人： Juergen Burger , Toralf Bork
发明人： Juergen Burger , Toralf Bork
CPC分类号： A61B5/6846 , A61B5/0031 , A61B5/031 , A61B5/032 , A61B2560/0223 , A61B2562/0247 , G01L19/02 , G01L27/002
摘要： A pressure sensor having a substrate and a first, deformable membrane, partially supported by the substrate, which generates a first sensor reading when deformed by pressure. A second membrane is contiguous to the first membrane. When the second membrane is energized, it deforms the first membrane to alter the first sensor reading.
摘要翻译： 一种压力传感器，其具有基板和由基板部分支撑的第一可变形膜，当通过压力变形时产生第一传感器读数。 第二个膜与第一个膜相邻。 当第二个膜通电时，它会使第一个膜变形，从而改变第一个传感器读数。
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公开(公告)号：US07069779B2
公开(公告)日：2006-07-04
申请号：US10881425
申请日：2004-06-30
申请人： Frank Zumkehr , Juergen Burger , Toralf Bork , Alec Ginggen
发明人： Frank Zumkehr , Juergen Burger , Toralf Bork , Alec Ginggen
IPC分类号： G01F1/68
CPC分类号： A61B5/028 , G01F1/6845
摘要： A thermal flow sensor has a first substrate, second substrate and a third substrate, each of which has a first side and a second opposite side. The first substrate is connected to the second substrate such that the second side of the first substrate abuts the first side of the second substrate. The third substrate is connected to the second substrate such that the second side of the second substrate abuts the first side of the third substrate. The second substrate has a groove formed therein so as to form a conduit bounded by the second substrate and the second side of the first substrate and the first side of the third substrate. A heater is disposed on the first side of the first substrate opposed to the conduit. A first temperature sensor is disposed on the first side of the first substrate opposed to the conduit.
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9.发明申请公开(公告)号：US20090326517A1
公开(公告)日：2009-12-31
申请号：US12147605
申请日：2008-06-27
申请人： Toralf Bork , Francois Bianchi
发明人： Toralf Bork , Francois Bianchi
CPC分类号： A61M5/14276 , A61M5/141 , A61M5/16813 , A61M5/16877 , A61M2205/0238 , A61M2205/0244 , A61M2205/0255 , A61M2205/0261 , F16K99/0001 , F16K99/0017 , F16K2099/0074 , F16K2099/0088
摘要： An erosion-resistant capillary chip for use with in an infusion pump that is made from a silicon substrate having a first surface that includes a micro groove etched therein and a glass plate laminated to the first surface. The glass plate covers the micro groove so that a micro fluid conduit is created. The glass plate includes an inlet bore that connects with the micro fluid conduit and the silicon substrate includes an outlet bore that connects with the micro fluid conduit so that a drug solution entering the inlet bore from the infusion pump may pass through the micro fluid conduit at a restricted flow rate to the outlet bore and thereafter to a target site of a patient. The micro groove includes a passivation layer made from silicon nitride or silicon carbide that protects the micro groove against erosion from passing fluids having high basic or high acidic pH levels. A method for making the capillary chip is disclosed, as well as an infusion pump incorporating the improved capillary chip.
摘要翻译： 一种用于输注泵的抗侵蚀毛细管芯片，其由具有第一表面的硅衬底制成，所述第一表面包括蚀刻在其中的微槽和层压到所述第一表面的玻璃板。 玻璃板覆盖微槽，从而产生微流体导管。 玻璃板包括与微流体导管连接的入口孔，并且硅衬底包括与微流体导管连接的出口孔，使得从输注泵进入入口孔的药液可以通过微流体导管 对出口孔的限制流速，此后到病人的目标部位。 微槽包括由氮化硅或碳化硅制成的钝化层，其保护微槽免受通过具有高碱性或高酸性pH水平的流体侵蚀。 公开了制造毛细管芯片的方法，以及结合改进的毛细管芯片的输液泵。
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公开(公告)号：US20110071557A1
公开(公告)日：2011-03-24
申请号：US12562250
申请日：2009-09-18
申请人： Daniel F. Dlugos, JR. , Toralf Bork , Christine H. Chen , Rocco Crivelli , Donna L. Korvick , David T. Krumanaker , Timothy P. Lessek , Amy L. Marcotte , Jeffrey D. Messerly , Daniel J. Mumaw , Anil K. Nalagatla , David N. Plescia , Frederick E. Shelton, IV , Jeffrey S. Swayze , Patrick J. Swindon , Mark Tsonton , Scott A. Woodruff
发明人： Daniel F. Dlugos, JR. , Toralf Bork , Christine H. Chen , Rocco Crivelli , Donna L. Korvick , David T. Krumanaker , Timothy P. Lessek , Amy L. Marcotte , Jeffrey D. Messerly , Daniel J. Mumaw , Anil K. Nalagatla , David N. Plescia , Frederick E. Shelton, IV , Jeffrey S. Swayze , Patrick J. Swindon , Mark Tsonton , Scott A. Woodruff
IPC分类号： A61B17/122 , A61F2/04
CPC分类号： A61F5/0059 , A61B17/12009 , A61F2/0036 , A61F5/003 , A61F5/0053 , A61F5/0056 , A61F2250/0002
摘要： An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. A symmetrical drive system including a drive element associated with and engaging the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct is further provided. In accordance with an alternate embodiment an apparatus for regulating the functioning of a patient's organ or duct including an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. The tension element is composed of a flexible first member and a flexible second member, wherein the flexible first member is movable relative to the flexible second member. A drive element is associated with and engages the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct.
摘要翻译： 用于调节患者器官或管道的功能的装置包括具有第一端和第二端的细长构件。 紧固件设置在细长构件的第一端上。 紧固件构造成接合细长构件的第二端，使得细长构件围绕器官或管道形成环。 张力元件设置成在细长构件内移动。 进一步提供一种对称的驱动系统，其包括与紧张元件相关联并与其接合的驱动元件，用于使张力元件控制细长构件对患者身体器官或管道施加的张力。 根据替代实施例，一种用于调节患者器官或管道的功能的装置，包括具有第一端和第二端的细长构件。 紧固件设置在细长构件的第一端上。 紧固件构造成接合细长构件的第二端，使得细长构件围绕器官或管道形成环。 张力元件设置成在细长构件内移动。 张力元件由柔性第一构件和柔性第二构件构成，其中柔性第一构件可相对于柔性第二构件移动。 驱动元件与张力元件相关联并与其接合，用于使张力元件控制由细长构件施加的抗张力抵靠患者身体器官或管道的张力。
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