利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

104 条记录 (耗时 0.031 秒)

    3D Ultrasonic imaging method
    1.
    发明申请
    3D Ultrasonic imaging method 审中-公开
    3D超声波成像方法

    公开(公告)号：US20080139937A1

    公开(公告)日：2008-06-12

    申请号：US11974689

    申请日：2007-10-15

    申请人： Timothy J. Nohara ,  Peter Weber ,  Richard Bernardi

    发明人： Timothy J. Nohara ,  Peter Weber ,  Richard Bernardi

    IPC分类号： A61B8/00

    CPC分类号： G01S15/8927 ,  A61B8/483 ,  G01S7/52044 ,  G01S7/52047 ,  G01S15/8925 ,  G01S15/8993 ,  G10K11/346

    摘要： A probe for electronic volume data acquisition using ultrasound incorporates a plurality of transducer elements arranged in a two dimensional array having an azimuth direction and an elevation direction. The transducer elements have a first element size in the azimuth dimension and a second element size in the elevation dimension. At least one of the first and second element sizes is at least twice a characteristic wavelength of a waveform used to drive the array of transducer elements, where the characteristic wavelength is defined as the wavelength corresponding to a center frequency of the waveform. Image data is generated in a scanning process using a CAC-BF technique in an azimuth dimension and/or an elevation dimension, to form an ultrasound image line, image plane, or image data cube.

    摘要翻译： 用于使用超声波的电子体积数据采集的探头包括以具有方位角方向和仰角方向的二维阵列排列的多个换能器元件。 换能器元件具有方位角尺寸中的第一元件尺寸和高度尺寸中的第二元件尺寸。 第一和第二元件尺寸中的至少一个是用于驱动换能器元件阵列的波形的特征波长的至少两倍，其中特征波长被定义为对应于波形的中心频率的波长。 图像数据在使用CAC-BF技术的方位角尺寸和/或仰角尺寸的扫描过程中产生，以形成超声图像线，图像平面或图像数据立方体。

    3D ultrasonic imaging apparatus and method
    2.
    发明授权
    3D ultrasonic imaging apparatus and method 有权
    3D超声波成像设备及方法

    公开(公告)号：US07285094B2

    公开(公告)日：2007-10-23

    申请号：US10353152

    申请日：2003-01-28

    申请人： Timothy J. Nohara ,  Peter Weber ,  Richard Bernardi

    发明人： Timothy J. Nohara ,  Peter Weber ,  Richard Bernardi

    IPC分类号： A61B8/00

    CPC分类号： G01S15/8927 ,  A61B8/483 ,  G01S7/52044 ,  G01S7/52047 ,  G01S15/8925 ,  G01S15/8993 ,  G10K11/346

    摘要： A probe for electronic volume data acquisition using ultrasound incorporates a plurality of transducer elements arranged in a two dimensional array having an azimuth direction and an elevation direction. The transducer elements have a first element size in the azimuth dimension and a second element size in the elevation dimension. At least one of the first and second element sizes is at least twice a characteristic wavelength of a waveform used to drive the array of transducer elements, where the characteristic wavelength is defined as the wavelength corresponding to a center frequency of the waveform. Image data is generated in a scanning process using a CAC-BF technique in an azimuth dimension and/or an elevation dimension, to form an ultrasound image line, image plane, or image data cube.

    摘要翻译： 用于使用超声波的电子体积数据采集的探头包括以具有方位角方向和仰角方向的二维阵列排列的多个换能器元件。 换能器元件具有方位角尺寸中的第一元件尺寸和高度尺寸中的第二元件尺寸。 第一和第二元件尺寸中的至少一个是用于驱动换能器元件阵列的波形的特征波长的至少两倍，其中特征波长被定义为对应于波形的中心频率的波长。 图像数据在使用CAC-BF技术的方位角尺寸和/或仰角尺寸的扫描过程中产生，以形成超声图像线，图像平面或图像数据立方体。

    Ultrasonic medical device and associated method
    3.
    发明授权
    Ultrasonic medical device and associated method 失效
    超声波医疗器械及相关方法

    公开(公告)号：US08235907B2

    公开(公告)日：2012-08-07

    申请号：US12074869

    申请日：2008-03-06

    申请人： Peter J. Wilk ,  Timothy J. Nohara ,  Peter Weber

    发明人： Peter J. Wilk ,  Timothy J. Nohara ,  Peter Weber

    IPC分类号： A61B8/00

    CPC分类号： A61B8/483 ,  A61B5/6804 ,  A61B8/00 ,  A61B8/08 ,  A61B8/13 ,  A61B8/4227 ,  A61B8/4281 ,  A61B8/4494 ,  A61B17/3403 ,  A61B34/10 ,  A61B2017/3413 ,  A61B2017/3492 ,  A61B2090/378 ,  Y10S128/916

    摘要： A medical system includes a carrier and a multiplicity of electromechanical transducers mounted to the carrier, the transducers being disposable in effective pressure-wave-transmitting contact with a patient. Energization componentry is operatively connected to a first plurality of the transducers for supplying the same with electrical signals of at least one pre-established ultrasonic frequency to produce first pressure waves in the patient. A control unit is operatively connected to the energization componentry and includes an electronic analyzer operatively connected to a second plurality of the transducers for performing electronic 3D volumetric data acquisition and imaging (which includes determining three-dimensional shapes) of internal tissue structures of the patient by analyzing signals generated by the second plurality of the transducers in response to second pressure waves produced at the internal tissue structures in response to the first pressure waves. The control unit includes phased-array signal processing circuitry for effectuating an electronic scanning of the internal tissue structures which facilitates one-dimensional (vector), 2D (planar), and 3D (volume) data acquisition. The control unit further includes circuitry for defining multiple data gathering apertures and for coherently combining structural data from the respective apertures to increase spatial resolution. When the data gathering apertures are contained in a flexible web or carrier so that the instantaneous positions of the data gathering apertures are unknown, a self-cohering algorithm is used to determine their positions so that coherent aperture combining can be performed.

    摘要翻译： 医疗系统包括载体和安装到载体上的多个机电换能器，换能器与患者有效的压力波传播接触一次。 通电组件可操作地连接到第一组多个换能器，以向其提供至少一个预先建立的超声频率的电信号，以在患者体内产生第一压力波。 控制单元可操作地连接到通电组件，并且包括可操作地连接到第二多个换能器的电子分析器，用于通过以下步骤执行电子3D体积数据采集和成像（其包括确定三维形状）的患者的内部组织结构 响应于在第一压力波响应于在内部组织结构处产生的第二压力波来分析由第二多个换能器产生的信号。 控制单元包括相控阵信号处理电路，用于实现促进一维（矢量），2D（平面）和3D（体积）数据采集的内部组织结构的电子扫描。 控制单元还包括用于定义多个数据收集孔并用于相干地组合来自相应孔的结构数据以增加空间分辨率的电路。 当数据收集孔被包含在柔性幅材或载体中，使得数据收集孔的瞬时位置是未知的时，使用自我聚焦算法来确定它们的位置，从而可以执行相干孔结合。

    Ultrasonic medical device and associated method
    4.
    发明授权
    Ultrasonic medical device and associated method 失效
    超声波医疗器械及相关方法

    公开(公告)号：US07597665B2

    公开(公告)日：2009-10-06

    申请号：US10663084

    申请日：2003-09-16

    申请人： Peter J. Wilk ,  Timothy J. Nohara ,  Peter Weber

    发明人： Peter J. Wilk ,  Timothy J. Nohara ,  Peter Weber

    IPC分类号： A61B8/14

    CPC分类号： A61B8/483 ,  A61B5/6804 ,  A61B8/00 ,  A61B8/08 ,  A61B8/13 ,  A61B8/4227 ,  A61B8/4281 ,  A61B8/4494 ,  A61B17/3403 ,  A61B34/10 ,  A61B2017/3413 ,  A61B2017/3492 ,  A61B2090/378 ,  Y10S128/916

    摘要： A medical system includes a multiplicity of electromechanical transducers disposable in effective pressure-wave-transmitting contact with a patient and mounted to a carrier. Energization componentry is operatively connected to a first plurality of the transducers for supplying the same with electrical signals to produce first pressure waves in the patient. A control unit is operatively connected to the energization componentry and includes an electronic analyzer operatively connected to a second plurality of the transducers for performing electronic 3D volumetric data acquisition and imaging of internal tissue structures. The control unit includes phased-array signal processing circuitry for effectuating an electronic scanning of the internal tissue structures which facilitates one-dimensional, 2D, and 3D data acquisition and circuitry for defining multiple data gathering apertures and for coherently combining structural data from the respective apertures to increase spatial resolution. When the instantaneous positions of the data gathering apertures are unknown, a self-cohering algorithm is used to determine their positions so that coherent aperture combining can be performed.

    摘要翻译： 医疗系统包括多个机电换能器，其一次性与病人有效的压力波传播接触并安装到载体上。 通电组件可操作地连接到第一组多个换能器，以向其提供电信号以在患者体内产生第一压力波。 控制单元可操作地连接到通电组件，并且包括可操作地连接到第二多个换能器的电子分析器，用于执行电子3D体积数据采集和内部组织结构的成像。 控制单元包括用于实现内部组织结构的电子扫描的相控阵信号处理电路，其促进一维，二维和三维数据采集，以及用于定义多个数据收集孔的电路，以及用于相干地组合来自各个孔的结构数据 以增加空间分辨率。 当数据收集孔的瞬时位置未知时，使用自我聚焦算法来确定它们的位置，从而可以执行相干孔径组合。

    Real-time 3D ultrasonic imaging apparatus and method
    5.
    发明授权
    Real-time 3D ultrasonic imaging apparatus and method 有权
    实时三维超声成像设备及方法

    公开(公告)号：US07914454B2

    公开(公告)日：2011-03-29

    申请号：US10876743

    申请日：2004-06-25

    申请人： Peter Weber ,  Timothy J Nohara ,  Al-Nasir Premji

    发明人： Peter Weber ,  Timothy J Nohara ,  Al-Nasir Premji

    IPC分类号： A61B6/00

    CPC分类号： A61B8/483 ,  G01S7/52047 ,  G01S15/8925 ,  G01S15/8927 ,  G01S15/8993 ,  G01S15/8997

    摘要： A method and apparatus for electronic volume data acquisition using ultrasound generates image data in a scanning and imaging process known as coherent aperture combining beamforming (CAC-BF). The CAC-BF technique can be applied in an azimuth dimension and/or an elevation dimension, to form an ultrasound image line, image plane, or image data cube. Several innovations relating to the design and ordering of shots and efficient weighting algorithms that address various performance issues associated with B-mode and other modes such as Doppler, and harmonic imaging are disclosed. The invention has significant advantages over other synthetic aperture imaging techniques and conventional imaging techniques by supporting higher resolution, larger volumes and/or shorter acquisition times than comparative techniques, using similar system hardware complexity.

    摘要翻译： 用于使用超声波的电子体积数据采集的方法和装置在被称为相干孔径组合波束形成（CAC-BF）的扫描和成像过程中产生图像数据。 CAC-BF技术可以应用于方位角尺寸和/或高程尺寸，以形成超声图像线，图像平面或图像数据立方体。 公开了与针对B模式和其他模式（如多普勒和谐波成像）相关的各种性能问题的射击设计和排序以及高效加权算法的几项创新。 通过使用类似的系统硬件复杂性，通过支持比比较技术更高的分辨率，更大的体积和/或更短的采集时间，本发明具有优于其它合成孔径成像技术和常规成像技术的优点。

    CRYSTAL STRUCTURE OF AURORA-2 PROTEIN AND BINDING POCKETS THEREOF
    9.
    发明申请
    CRYSTAL STRUCTURE OF AURORA-2 PROTEIN AND BINDING POCKETS THEREOF 失效
    AURORA-2蛋白质的结晶结构及其结合点

    公开(公告)号：US20110104782A1

    公开(公告)日：2011-05-05

    申请号：US12890826

    申请日：2010-09-27

    申请人： Graham Cheetham ,  Ronald Knegtel ,  Lovorka Swenson ,  Joyce T. Coll ,  Suzanne Renwick ,  Peter Weber

    发明人： Graham Cheetham ,  Ronald Knegtel ,  Lovorka Swenson ,  Joyce T. Coll ,  Suzanne Renwick ,  Peter Weber

    IPC分类号： C12N9/96 ,  C12N9/12

    CPC分类号： C12N9/1205 ,  C07K2299/00

    摘要： The present invention provides crystalline molecules or molecular complexes which comprise binding pockets of Aurora-2 or its homologues. The invention also provides crystals comprising Aurora-2. The present invention also relates to a computer comprising a data storage medium encoded with the structural coordinates of Aurora-2 binding pockets and methods of using a computer to evaluate the ability of a compound to bind to the molecule or molecular complex. This invention also provides methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. In addition, this invention provides methods of using the structure coordinates to screen for and design compounds, including inhibitory compounds, that bind to Aurora-2 or homologues thereof.

    摘要翻译： 本发明提供包含Aurora-2或其同系物的结合口袋的结晶分子或分子复合物。 本发明还提供了包含Aurora-2的晶体。 本发明还涉及包含用Aurora-2结合口袋的结构座标编码的数据存储介质的计算机，以及使用计算机评价化合物结合分子或分子复合物的能力的方法。 本发明还提供了使用结构坐标来解决同源蛋白质或蛋白质复合物的结构的方法。 此外，本发明提供了使用结构坐标筛选和设计结合Aurora-2或其同系物的化合物（包括抑制性化合物）的方法。

    Method and plant for producing low-temperature coke
    10.
    发明授权
    Method and plant for producing low-temperature coke 失效
    生产低温焦炭的方法和装置

    公开(公告)号：US07803268B2

    公开(公告)日：2010-09-28

    申请号：US10540073

    申请日：2003-12-01

    申请人： Andreas Orth ,  Martin Hirsch ,  Peter Weber

    发明人： Andreas Orth ,  Martin Hirsch ,  Peter Weber

    IPC分类号： C10G9/14 ,  B01J8/18

    CPC分类号： C10B49/10 ,  C10B53/04

    摘要： The present invention relates to a method and a plant for producing low 15 temperature coke, in which granular coal and possibly further solids are heated to a temperature of 700 to 1050° C. in a fluidized-bed reactor (2) by means of an oxygen-containing gas. To improve the utilization of energy it is proposed to introduce a first gas or gas mixture from below through at least one gas supply tube (3) into a mixing chamber region (8) of the reactor (2), the gas supply tube (3) being at least partly surrounded by a stationary annular fluidized bed (6) which is fluidized by supplying fluidizing gas. The gas velocities of the first gas or gas mixture and of the fluidizing gas for the annular fluidized bed (6) are adjusted such that the Particle-Froude-Numbers in the gas supply tube (3) are between 1 and 100, in the annular fluidized bed (6) between 0.02 and 2 and in the 25 mixing chamber (8) between 0.3 and 30.

    摘要翻译： 本发明涉及一种用于生产低温度焦炭的方法和设备，其中颗粒煤和可能的其它固体在流化床反应器（2）中通过以下方式加热至700至1050℃的温度： 含氧气体。 为了提高能量利用率，建议从下方将至少一个气体供给管（3）的第一气体或气体混合物引入反应器（2）的混合室区域（8），气体供给管（3） ）至少部分地被固定的环形流化床（6）包围，所述固定环形流化床通过供应流化气体而被流化。 调整第一气体或气体混合物和用于环形流化床（6）的流化气体的气体速度，使得气体供应管（3）中的“微粒 - 弗劳德数”为1至100，在环形 流化床（6）在0.02和2之间，在25混合室（8）中在0.3和30之间。