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18 条记录 (耗时 0.041 秒)

    Amidopyrazole Derivative
    5.
    发明申请
    Amidopyrazole Derivative 审中-公开
    吡唑衍生物

    公开(公告)号：US20070219210A1

    公开(公告)日：2007-09-20

    申请号：US10584632

    申请日：2004-12-27

    申请人： Naoaki Kanaya ,  Takashi Ishiyama ,  Ryo Muto ,  Yuichi Ochiai ,  Toshiyuki Watanabe ,  Noriko Shima

    发明人： Naoaki Kanaya ,  Takashi Ishiyama ,  Ryo Muto ,  Yuichi Ochiai ,  Toshiyuki Watanabe ,  Noriko Shima

    IPC分类号： A61K31/415 ,  A61K31/4427 ,  A61K31/497 ,  A61K31/501 ,  C07D231/04 ,  C07D401/14

    CPC分类号： C07D401/14 ,  C07D401/04 ,  C07D403/04 ,  C07D403/14 ,  C07D405/14 ,  C07D417/14

    摘要： A platelet coagulation inhibitor which inhibits neither COX-1 nor COX-2 is provided. The inhibitor is a compound represented by general formula (I): wherein Ar1 and Ar2 independently represent a 5- or 6-membered aromatic heterocyclic group optionally substituted with 1 to 3 substituents, or a phenyl group optionally substituted with 1 to 3 substituents; R1 represents a lower acyl group, carboxyl group, a lower alkoxy carbonyl group, a lower alkoxy group, a lower alkyl group optionally substituted with 1 or 2 substituents, a carbamoyl group optionally substituted with 1 or 2 substituents, an oxamoyl group optionally substituted with 1 or 2 substituents, an amino group optionally substituted with 1 or 2 substituents, a 4- to 7-membered alicyclic heterocyclic group optionally substituted with 1 or 2 substituents, a phenyl group optionally substituted with 1 to 3 substituents, or a 5- or 6-membered aromatic heterocyclic group optionally substituted with 1 to 3 substituents; and R2 represents hydrogen atom, a halogeno group, or the like.

    摘要翻译： 提供了既不抑制COX-1也不抑制COX-2的血小板凝血抑制剂。 抑制剂是由通式（I）表示的化合物：其中Ar 1和Ar 2独立地表示任选被1至 3个取代基或任选被1至3个取代基取代的苯基; R 1表示低级酰基，羧基，低级烷氧基羰基，低级烷氧基，任选被1或2个取代基取代的低级烷基，任选被1或2个取代基取代的氨基甲酰基，任选被 1或2个取代基，任选被1或2个取代基取代的氨基，任选被1或2个取代基取代的4-至7-元脂环族杂环基，任选被1至3个取代基取代的苯基，或5-或 任选被1至3个取代基取代的6元芳族杂环基; R 2表示氢原子，卤代基等。

    Pyrazole Derivatives
    6.
    发明申请
    Pyrazole Derivatives 审中-公开
    吡唑衍生物

    公开(公告)号：US20080064682A1

    公开(公告)日：2008-03-13

    申请号：US11571387

    申请日：2005-07-01

    申请人： Naoaki Kanaya ,  Takashi Ishiyama ,  Ryo Muto ,  Toshiyuki Watanabe ,  Yuichi Ochiai

    发明人： Naoaki Kanaya ,  Takashi Ishiyama ,  Ryo Muto ,  Toshiyuki Watanabe ,  Yuichi Ochiai

    IPC分类号： A61K31/55 ,  A61K31/415 ,  A61K31/44 ,  A61P9/00 ,  C07D231/02 ,  C07D401/00 ,  C07D413/00 ,  C07D243/08 ,  C07D211/68 ,  A61K31/445 ,  A61K31/5375

    CPC分类号： C07D401/14 ,  C07D417/14

    摘要： A compound represented by formula (I): (wherein Ar1 represents a phenyl group which may have 1 to 3 substituents, or a non-substituted 5- or 6-membered aromatic heterocyclic group; Ar2 represents (i) a non-substituted phenyl group, (ii) a phenyl group which has been substituted by a lower alkyl group having 1 to 3 groups or atoms selected from among a carbamoyl group, an amino group, a hydroxyl group, a lower alkoxy group, and a halogen atom, or (iii) a 5- or 6-membered nitrogen-containing aromatic heterocyclic group which has been substituted by 1 to 3 groups or atoms selected from among a lower alkyl group, a lower alkynyl group, a lower alkanoyl group, a carbamoyl group, a cyano group, an amino group, a hydroxyl group, a lower alkoxy group, and a halogen atom; and X represents a group represented by formula (II): (wherein the ring structure represents a 4- to 7-membered heterocyclic group which may have, in addition to the nitrogen atom shown in formula (II), one heteroatom selected from among nitrogen, oxygen, a sulfur, and which may be substituted by 1 to 4 groups or atoms selected from among a lower alkyl group, a carbamoyl group, an amino group, a hydroxyl group, a lower alkoxy group, an oxo group a lower alkanoyl group, a lower alkylsulfonyl group, and a halogen atom)), a salt thereof, a solvate of the compound or the salt, and a drug.

    摘要翻译： 由式（I）表示的化合物：其中Ar 1表示可具有1至3个取代基的苯基或未取代的5或6元芳族杂环基团; Ar 2 表示（i）未取代的苯基，（ii）被具有1〜3个选自氨基甲酰基，氨基， 羟基，低级烷氧基和卤素原子，或（iii）被1〜3个选自低级烷基，低级烷氧基， 低级炔基，低级烷酰基，氨基甲酰基，氰基，氨基，羟基，低级烷氧基和卤素原子; X表示由式（II）表示的基团：（其中 环结构表示除了式（II）所示的氮原子之外还可以具有o至4个的7-元杂环基 选自氮，氧，硫的杂原子，可以被1〜4个选自低级烷基，氨基甲酰基，氨基，羟基，低级烷氧基， 氧代基，低级烷酰基，低级烷基磺酰基和卤原子）），其盐，化合物或其盐的溶剂化物和药物。

    Torque converter
    7.
    发明授权
    Torque converter 有权
    转矩转换器

    公开(公告)号：US09316273B2

    公开(公告)日：2016-04-19

    申请号：US13817798

    申请日：2011-07-21

    申请人： Tokimori Saka ,  Norio Iwashita ,  Takashi Ishiyama ,  Hidetoshi Maeta

    发明人： Tokimori Saka ,  Norio Iwashita ,  Takashi Ishiyama ,  Hidetoshi Maeta

    IPC分类号： F16D39/00 ,  F16H45/02 ,  F16F15/12

    CPC分类号： F16D39/00 ,  F16F15/12 ,  F16H45/02 ,  F16H2041/246 ,  F16H2045/0205 ,  F16H2045/021 ,  F16H2045/0284 ,  F16H2045/0294

    摘要： Provided is a torque converter (1) which comprises: a casing (10) coupled to an output shaft of an engine; a torus (T) defined by a pump (20), a turbine (30) and a stator (40) each disposed within the casing (10); a multi-plate lockup clutch (60) adapted to directly couple the turbine (30) and the casing (10); and a lockup damper (70) adapted to absorb shock during engagement of the lockup clutch (60). The lockup clutch (60) and the lockup damper (70) are arranged within a space between the torus (T) and a surface of the casing (10) on the side of the engine, in an axially overlapping relation. The lockup clutch (60) is disposed on a radially inner side with respect to a widest region (T1) of the torus (T), and the lockup damper (70) is disposed on a radially outer side with respect to the widest region (T1). This makes it possible to engage the lockup clutch (60) with excellent response while suppressing shock, and shorten an overall length of an automatic transmission.

    摘要翻译： 提供一种变矩器（1），其包括：联接到发动机的输出轴的壳体（10） 每个设置在所述壳体（10）内的由泵（20），涡轮机（30）和定子（40）限定的环面（T）; 适于直接联接所述涡轮机（30）和所述壳体（10）的多板锁止离合器（60）; 以及适于在所述锁止离合器（60）的接合期间吸收冲击的锁止阻尼器（70）。 锁止离合器（60）和锁止阻尼器（70）以轴向重叠的关系布置在环形面（T）与壳体（10）的在发动机侧面上的空间之间。 锁止离合器（60）相对于环面（T）的最宽区域（T1）设置在径向内侧，锁止阻尼器（70）相对于最宽区域（径向外侧）设置 T1）。 这使得可以在抑制冲击的同时使锁止离合器（60）具有优异的响应，并缩短自动变速器的总长度。

    Torque converter
    8.
    发明授权
    Torque converter 有权
    转矩转换器

    公开(公告)号：US08939267B2

    公开(公告)日：2015-01-27

    申请号：US13821946

    申请日：2011-07-21

    申请人： Norio Iwashita ,  Tokimori Saka ,  Takashi Ishiyama ,  Hidetoshi Maeta

    发明人： Norio Iwashita ,  Tokimori Saka ,  Takashi Ishiyama ,  Hidetoshi Maeta

    IPC分类号： F16H45/02 ,  F16D33/18 ,  F16H41/30

    CPC分类号： F16D33/18 ,  F16H41/30 ,  F16H45/02 ,  F16H2045/021 ,  F16H2045/0284

    摘要： A torque converter includes, in a case coupled to an output shaft of an engine, a torus formed from a pump, a turbine and a stator having a one-way clutch on the inside thereof, and a lock-up clutch. In addition, in this torque converter, a fluid from a pump is introduced from a space between a stator shaft (F2) and a turbine shaft (F1), and discharged from a space between a pump sleeve (23) and the stator shaft (F2) through a space where the lock-up clutch is disposed and the torus. Moreover, this torque converter further includes a seal member (80) which is disposed at a side that is closer to the engine than a spline engagement part (P2) of an inner race (52) and the stator shaft (F2), and seals a space between an inner peripheral face of the inner race (52) and an outer peripheral face of the stator shaft (F2).

    摘要翻译： 在与发动机的输出轴联接的情况下，变矩器包括由泵，涡轮和在其内部具有单向离合器的定子形成的环形圈，以及锁止离合器。 此外，在该液力变矩器中，来自泵的流体从定子轴（F2）和涡轮轴（F1）之间的空间引入，并从泵套（23）与定子轴（ F2）通过设置锁止离合器的空间和环面。 此外，该变矩器还具备密封部件（80），该密封部件设置在比内圈（52）和定子轴（F2）的花键接合部（P2）更靠近发动机的一侧，并且密封 内座圈（52）的内周面与定子轴（F2）的外周面之间的空间。

    Torque converter
    9.
    发明授权
    Torque converter 有权
    转矩转换器

    公开(公告)号：US08925700B2

    公开(公告)日：2015-01-06

    申请号：US13817791

    申请日：2011-07-27

    申请人： Takeshi Kawamoto ,  Tokimori Saka ,  Norio Iwashita ,  Takashi Ishiyama ,  Hidetoshi Maeta

    发明人： Takeshi Kawamoto ,  Tokimori Saka ,  Norio Iwashita ,  Takashi Ishiyama ,  Hidetoshi Maeta

    IPC分类号： F16H45/02 ,  F16D39/00

    CPC分类号： F16D39/00 ,  F16H45/02 ,  F16H2045/021 ,  F16H2045/0284

    摘要： Disclosed is a torque converter (1) which comprises: a casing (10) coupled to an output shaft of an engine; a torus (T) defined by a pump (20), a turbine (30) and a stator (40) each disposed within the casing (10); a lockup clutch (60) adapted to directly couple the turbine (30) and the casing (10); and a lockup damper (70) adapted to absorb shock during engagement of the lockup clutch (60). The turbine (30) has an outer peripheral portion (31a) bulging toward the engine to define a part of the torus (T), an inner peripheral portion (31c) located on the side of the engine with respect to a one-way clutch (50) supporting the stator (40), and an intermediate portion (31b) formed to be concaved toward a side opposite to the engine, in a radial position between the outer peripheral portion (31a) and the inner peripheral portion (31c). A part (75) of the lockup damper (70) is disposed on the side of the engine with respect to the intermediate portion (31b) and in a position axially overlapping with the torus (T). This makes it possible to allow a torque converter to be axially downsized.

    摘要翻译： 公开了一种变矩器（1），其包括：联接到发动机的输出轴的壳体（10） 每个设置在所述壳体（10）内的由泵（20），涡轮机（30）和定子（40）限定的环面（T）; 适于直接联接所述涡轮机（30）和所述壳体（10）的锁止离合器（60）; 以及适于在所述锁止离合器（60）的接合期间吸收冲击的锁止阻尼器（70）。 涡轮机（30）具有朝向发动机膨胀以限定环面（T）的一部分的外周部（31a），相对于单向离合器位于发动机侧的内周部（31c） （50），以及在外周部（31a）和内周部（31c）之间的径向位置形成为朝向与发动机相反的一侧凹陷的中间部（31b）。 锁止阻尼器（70）的一部分（75）相对于中间部分（31b）设置在发动机的侧面并且在与环面（T）轴向重叠的位置。 这使得可以使变矩器轴向地小型化。

    TORQUE CONVERTER
    10.
    发明申请
    TORQUE CONVERTER 有权
    扭矩转换器

    公开(公告)号：US20130153352A1

    公开(公告)日：2013-06-20

    申请号：US13817791

    申请日：2011-07-27

    申请人： Takeshi Kawamoto ,  Tokimori Saka ,  Norio Iwashita ,  Takashi Ishiyama ,  Hidetoshi Maeta

    发明人： Takeshi Kawamoto ,  Tokimori Saka ,  Norio Iwashita ,  Takashi Ishiyama ,  Hidetoshi Maeta

    IPC分类号： F16D39/00

    CPC分类号： F16D39/00 ,  F16H45/02 ,  F16H2045/021 ,  F16H2045/0284

    摘要： Disclosed is a torque converter (1) which comprises: a casing (10) coupled to an output shaft of an engine; a torus (T) defined by a pump (20), a turbine (30) and a stator (40) each disposed within the casing (10); a lockup clutch (60) adapted to directly couple the turbine (30) and the casing (10); and a lockup damper (70) adapted to absorb shock during engagement of the lockup clutch (60). The turbine (30) has an outer peripheral portion (31a) bulging toward the engine to define a part of the torus (T), an inner peripheral portion (31c) located on the side of the engine with respect to a one-way clutch (50) supporting the stator (40), and an intermediate portion (31b) formed to be concaved toward a side opposite to the engine, in a radial position between the outer peripheral portion (31a) and the inner peripheral portion (31c). A part (75) of the lockup damper (70) is disposed on the side of the engine with respect to the intermediate portion (31b) and in a position axially overlapping with the torus (T). This makes it possible to allow a torque converter to be axially downsized.

    摘要翻译： 公开了一种变矩器（1），其包括：联接到发动机的输出轴的壳体（10） 每个设置在所述壳体（10）内的由泵（20），涡轮机（30）和定子（40）限定的环面（T）; 适于直接联接所述涡轮机（30）和所述壳体（10）的锁止离合器（60）; 以及适于在所述锁止离合器（60）的接合期间吸收冲击的锁止阻尼器（70）。 涡轮机（30）具有朝向发动机膨胀的外周部（31a），以限定环面（T）的一部分，相对于单向离合器位于发动机侧的内周部分（31c） （50），以及在外周部（31a）和内周部（31c）之间的径向位置形成为朝向与发动机相反的一侧凹陷的中间部（31b）。 锁止阻尼器（70）的一部分（75）相对于中间部分（31b）设置在发动机的侧面并且在与环面（T）轴向重叠的位置。 这使得可以使变矩器轴向地小型化。