公开(公告)号：US5645846A

公开(公告)日：1997-07-08

申请号：US582786

申请日：1996-01-04

申请人： Hiroaki Oka ,  Toshikazu Tomioka ,  Katsumi Tomita ,  Kenji Hoshino ,  Atsushi Nishino ,  Shigeharu Ueda

发明人： Hiroaki Oka ,  Toshikazu Tomioka ,  Katsumi Tomita ,  Kenji Hoshino ,  Atsushi Nishino ,  Shigeharu Ueda

IPC分类号： A01N59/16 ,  A01N59/20 ,  A61K9/16

CPC分类号： A01N59/16 ,  A01N59/20

摘要： An antiviral composition comprising: a thiosulfate salt and at least one of thiosulfate complex salt of a metal and a porous particulate carrier; said metal being at least one selected from the group consisting of silver, copper and zinc: said salts being carried on said porous particulate carrier. It is applicable to a wide range of living environment such as medical instruments and appliances, hygienic implements as well as kitchen utensils, and also demonstrates an antibacterial activity in addition to the antiviral activity. The composition releases its salts slowly to the environment and the antiviral and antibacterial activities of said composition lasts for a long period of time. A method for preparing said composition as well as an antiviral disinfection method and a virucidal disinfection fluid using said composition are also disclosed.

摘要翻译： 一种抗病毒组合物，其包含：硫代硫酸盐和金属的硫代硫酸盐配合盐和多孔颗粒载体中的至少一种; 所述金属为选自银，铜和锌中的至少一种金属：所述盐载于所述多孔颗粒载体上。 它适用于各种生活环境，如医疗仪器和电器，卫生用具以及厨房用具，除抗病毒活性外，还具有抗菌活性。 该组合物缓慢地将其盐释放到环境中，并且所述组合物的抗病毒和抗菌活性持续很长时间。 还公开了使用所述组合物制备所述组合物的方法以及抗病毒消毒方法和杀病毒消毒液。

公开(公告)号：US5651978A

公开(公告)日：1997-07-29

申请号：US693496

申请日：1996-08-02

申请人： Toshikazu Tomioka ,  Katsumi Tomita ,  Hiroaki Oka ,  Kenji Hoshino ,  Atsushi Nishino

发明人： Toshikazu Tomioka ,  Katsumi Tomita ,  Hiroaki Oka ,  Kenji Hoshino ,  Atsushi Nishino

IPC分类号： A01N59/16 ,  A01N25/26

CPC分类号： A01N59/16

摘要： An antibacterial composition having a heat-resistant property sufficient for avoiding its decomposition or discoloration at the resin molding temperature comprises; a silver thiosulfate complex salt carried on silica gel particles having an equilibrium water content of 10% or smaller, wherein at least part of the surface of the silica gel particles carrying said silver thiosulfate complex salt is covered with a coating layer composed of silicon dioxide formed by means of hydrolysis of an alkoxysilane.

摘要翻译： 具有足以避免其在树脂成型温度下分解或变色的耐热性的抗菌组合物包括： 将平均含水量为10％以下的硅胶粒子上载持的硫代硫酸银配合盐，其中载有所述硫代硫酸银配合盐的硅胶粒子表面的至少一部分被形成有二氧化硅的被覆层覆盖 通过烷氧基硅烷的水解。

公开(公告)号：US5516519A

公开(公告)日：1996-05-14

申请号：US420182

申请日：1995-04-11

申请人： Hiroaki Oka ,  Toshikazu Tomioka ,  Katsumi Tomita ,  Kenji Hoshino ,  Atsushi Nishino ,  Shigeharu Ueda

发明人： Hiroaki Oka ,  Toshikazu Tomioka ,  Katsumi Tomita ,  Kenji Hoshino ,  Atsushi Nishino ,  Shigeharu Ueda

IPC分类号： A01N59/16 ,  A01N59/20 ,  A61K9/16

CPC分类号： A01N59/16 ,  A01N59/20

摘要： An antiviral composition comprising: a thiosulfate salt and at least one of thiosulfate complex salt of a metal and a porous particulate carrier; said metal being at least one selected from the group consisting of silver, copper and zinc; said salts being carried on said porous particulate carrier. It is applicable to a wide range of living environment such as medical instruments and appliances, hygienic implements as well as kitchen utensils, and also demonstrates an antibacterial activity in addition to the antiviral activity. The composition releases its salts slowly to the environment and the antiviral and antibacterial activities of said composition lasts for a long period of time. A method for preparing said composition as well as an antiviral disinfection method and a virucidal disinfection fluid using said composition are also disclosed.

公开(公告)号：US5429819A

公开(公告)日：1995-07-04

申请号：US134124

申请日：1993-10-08

申请人： Hiroaki Oka ,  Toshikazu Tomioka ,  Katsumi Tomita ,  Kenji Hoshino ,  Atsushi Nishino ,  Shigeharu Ueda

发明人： Hiroaki Oka ,  Toshikazu Tomioka ,  Katsumi Tomita ,  Kenji Hoshino ,  Atsushi Nishino ,  Shigeharu Ueda

IPC分类号： A01N59/16 ,  A01N59/20 ,  A61K9/16

CPC分类号： A01N59/16 ,  A01N59/20

摘要： An antiviral composition comprising: a thiosulfate salt and at least one of thiosulfate complex salt of a metal and a porous particulate carrier; said metal being at least one selected from the group consisting of silver, copper and zinc; said salts being carried on said porous particulate carrier. It is applicable to a wide range of living environment such as medical instruments and appliances, hygienic implements as well as kitchen utensils, and also demonstrates an antibacterial activity in addition to the antiviral activity. The composition releases its salts slowly to the environment and the antiviral and antibacterial activities of said composition lasts for a long period of time. A method for preparing said composition as well as an antiviral disinfection method and a virucidal disinfection fluid using said composition are also disclosed.

摘要翻译： 一种抗病毒组合物，其包含：硫代硫酸盐和金属的硫代硫酸盐配合盐和多孔颗粒载体中的至少一种; 所述金属为选自银，铜和锌的至少一种; 所述盐被携带在所述多孔颗粒载体上。 它适用于各种生活环境，如医疗仪器和电器，卫生用具以及厨房用具，除抗病毒活性外，还具有抗菌活性。 该组合物缓慢地将其盐释放到环境中，并且所述组合物的抗病毒和抗菌活性持续很长时间。 还公开了使用所述组合物制备所述组合物的方法以及抗病毒消毒方法和杀病毒消毒液。

公开(公告)号：US08247218B2

公开(公告)日：2012-08-21

申请号：US12133452

申请日：2008-06-05

申请人： Masaya Nakatani ,  Nobuhiko Ozaki ,  Hiroaki Oka

发明人： Masaya Nakatani ,  Nobuhiko Ozaki ,  Hiroaki Oka

IPC分类号： C12M1/34

CPC分类号： G01N33/48728

摘要： A sensing element for measuring extracellular potential including a substrate, a well provided in a substrate, a guide section provided on the wall of the well, and a detective electrode formed at a lower surface of the substrate. The guide section is for guiding drug. The well is provided at the bottom with a depression, and a first throughhole penetrating through the depression and the lower surface of the substrate. The well is for mixing a subject cell, a culture solution and the drug together. The above-configured sensing element accurately measures a change generated by a subject cell.

摘要翻译： 用于测量细胞外电位的感测元件，包括衬底，设置在衬底中的阱，设置在阱的壁上的引导部分和形成在衬底的下表面处的检测电极。 指导部分是指导药物。 井在底部设置有凹陷，并且第一通孔穿过基底的凹陷和下表面。 该井用于将主体细胞，培养液和药物混合在一起。 上述构成的感测元件精确地测量由被摄体单元产生的变化。

公开(公告)号：US20100236859A1

公开(公告)日：2010-09-23

申请号：US12095736

申请日：2006-11-17

申请人： Kouji Kitahata ,  Naoki Uchida ,  Mitsuo Yoneda ,  Hiroaki Oka ,  Tomotaka Nakagawa ,  Masahiro Hayashi

发明人： Kouji Kitahata ,  Naoki Uchida ,  Mitsuo Yoneda ,  Hiroaki Oka ,  Tomotaka Nakagawa ,  Masahiro Hayashi

IPC分类号： B62D5/04 ,  C10M173/02 ,  F16H57/04

CPC分类号： B62D5/0409 ,  C10M149/14 ,  C10M149/20 ,  C10M169/00 ,  C10M2205/0285 ,  C10M2207/1256 ,  C10M2217/045 ,  C10N2230/08 ,  C10N2230/26 ,  C10N2230/76 ,  F16H57/041 ,  F16H57/0463 ,  Y10T74/19991

摘要： There provided a lubricant composition that without any excess increase of the steering torque of an electric power steering apparatus and without any generation of sliding noise, reduces rattling sound thereby excel in the effect of noise reduction in automobile compartment, and is capable of favorably sustaining the above effect even when continuously used in high-temperature environment for a prolonged period of time; a speed reduction gear using the lubricant composition; and an electric power steering apparatus. The lubricant composition includes buffer particles of a polyurethane resin synthesized by reacting a polycarbonate polyol, cross-linking agent having three or more active hydrogen groups per molecule and a polyisocyanate. The speed reduction gear (50) is filled with the lubricant composition. The electric power steering apparatus incorporates the speed reduction gear therein.

摘要翻译： 提供了一种润滑剂组合物，其没有电动转向装置的转向扭矩的任何过度增加，并且没有任何产生的滑动噪声，从而减少了咔嗒声，从而在汽车隔室中降低噪音的效果，并且能够有利地维持 即使在高温环境下长时间连续使用也能起到上述作用。 使用润滑剂组合物的减速装置; 和电动助力转向装置。 润滑剂组合物包括通过使聚碳酸酯多元醇，每分子具有三个或更多个活性氢基团的交联剂和多异氰酸酯反应合成的聚氨酯树脂的缓冲颗粒。 减速齿轮（50）填充有润滑剂组合物。 电动助力转向装置内装有减速装置。

公开(公告)号：US07736477B2

公开(公告)日：2010-06-15

申请号：US10595275

申请日：2005-07-14

申请人： Masaya Nakatani ,  Nobuhiko Ozaki ,  Hiroaki Oka

发明人： Masaya Nakatani ,  Nobuhiko Ozaki ,  Hiroaki Oka

IPC分类号： G01N33/487

CPC分类号： G01N33/48728

摘要： A probe for measuring an electric potential of a cell includes a plate having a surface having a first cavity provided therein, and a sensor element provided in the first cavity. A second cavity is provided in the bottomsurface of the first cavity. The first flow passage having first and second openings is provided in the plate. The first and second openings of the first flow passage open to the second cavity and outside the plate, respectively. The sensor element includes a thin plate, and a supporting substrate provided around the thin plate and in the first cavity of the plate. The thin plate has a through-hole therein having a first opening and a second opening communicating with the second cavity of the plate. The first flow passage allows fluid to flow therein. A sucking device is coupled with the second opening of the first flow passage as to suck the fluid flowing in the first flow passage. This probe can measure an electric potential of a cell floating in solution as it is in this environment.

摘要翻译： 用于测量电池的电位的探针包括具有设置在其中的具有第一腔的表面的板和设置在第一腔中的传感器元件。 在第一腔的底面设有第二腔。 具有第一和第二开口的第一流动通道设置在板中。 第一流动通道的第一和第二开口分别向第二腔室和板外开口。 传感器元件包括薄板，以及设置在薄板周围和板的第一腔中的支撑基板。 薄板的通孔中具有第一开口和与板的第二腔连通的第二开口。 第一流道允许流体流入其中。 抽吸装置与第一流动通道的第二开口联接以吸收在第一流动通道中流动的流体。 该探头可以在这种环境中测量浮动在溶液中的电池的电位。

公开(公告)号：US07594950B2

公开(公告)日：2009-09-29

申请号：US11490253

申请日：2006-07-21

申请人： Hiroaki Oka ,  Nariaki Oka

发明人： Hiroaki Oka ,  Nariaki Oka

IPC分类号： C22B9/02

CPC分类号： B22C9/086 ,  B22D43/005 ,  F27D3/1563

摘要： A method for removing slag comprises: preparing a filter 21 of heat-resistant porous ceramics, which passes a molten metal and catches slag, liquidizing metal material to form a molten metal A on which slag is floating; and traveling filter 21 along a surface of the molten metal A and removing slag. And a device for removing slag comprises: a filter 21 of heat-resistant porous ceramics, which passes a molten metal and catches slag; and a driving device for traveling filter 21 along a surface of the molten metal on which slag is floating and removing slag.

摘要翻译： 一种除渣方法包括：制备耐熔多孔陶瓷过滤器21，使过滤金属熔渣，使金属材料液化，形成熔渣，浮渣; 和沿着熔融金属A的表面的移动过滤器21，并去除渣。 另外，除渣装置包括：通过熔融金属并捕获炉渣的耐热多孔陶瓷过滤器21; 以及沿熔融金属浮渣并去除渣的熔融金属表面的行进过滤器21的驱动装置。

公开(公告)号：US20090239033A1

公开(公告)日：2009-09-24

申请号：US12359426

申请日：2009-01-26

申请人： Masaya Nakatani ,  Soichiro Hiraoka ,  Hiroshi Ushio ,  Akiyoshi Oshima ,  Hiroaki Oka ,  Fumiaki Emoto

发明人： Masaya Nakatani ,  Soichiro Hiraoka ,  Hiroshi Ushio ,  Akiyoshi Oshima ,  Hiroaki Oka ,  Fumiaki Emoto

IPC分类号： B32B3/10 ,  B44C1/22

CPC分类号： G01N33/48728 ,  Y10T428/24322

摘要： A diaphragm is formed by etching a substrate. This substrate has a first surface provided with a depression by isotropic dry etching, and a second surface opposite the first surface. Furthermore, a through-hole is formed from the depression to the second surface by anisotropic dry etching. The depression and the through-hole are formed by using one resist mask. The depression has a hemispherical shape or a semi-elliptical spherical shape.

摘要翻译： 通过蚀刻基板形成隔膜。 该基板具有通过各向同性干蚀刻设置有凹部的第一表面和与第一表面相对的第二表面。 此外，通过各向异性干蚀刻从凹陷形成通孔到第二表面。 通过使用一个抗蚀剂掩模形成凹陷和通孔。 凹陷具有半球形或半椭圆形球形。

公开(公告)号：US07297499B2

公开(公告)日：2007-11-20

申请号：US11489582

申请日：2006-07-20

申请人： Hidenobu Yaku ,  Hiroaki Oka ,  Tetsuo Yukimasa

发明人： Hidenobu Yaku ,  Hiroaki Oka ,  Tetsuo Yukimasa

IPC分类号： C12Q1/68 ,  C12P19/34

CPC分类号： C12Q1/6858 ,  C12Q2535/125 ,  C12Q2525/185

摘要： An object of the present invention is to provide an allele specific primer which is accompanied by less possibility of the false positive and enables definite discrimination when a base immediately adjacent to on the 3′ side of a target SNP base is C, while a base adjacent with one base spaced apart is T.According to the present invention, the 3′ end base is designed to be the base corresponding to SNP; the second base from the 3′ end to be T; the third base from the 3′ end to be any one of T, G or C; and the base sequence of from the fourth from the 3′ end to the 5′ end base to be completely complementary to the sequence of from a base three bases away from the target SNP base on the 3′ side to a desired base.

摘要翻译： 本发明的目的是提供一种等位基因特异性引物，当与目标SNP碱基的3'侧紧邻的碱基是C时，伴随着假阳性的可能性较小，并且能够进行确定的鉴别，而邻近的碱基 其中一个基座间隔开。根据本发明，3'端基被设计为对应于SNP的基座; 从3'端的第二个基地是T; 3'末端的第3个碱基为T，G或C任一个; 并且从3'末端到5'末端碱基的第四个碱基序列与从3'侧的目标SNP碱基到碱基的碱基三碱基的序列完全互补。