公开(公告)号：US10073082B2

公开(公告)日：2018-09-11

申请号：US15028846

申请日：2014-10-03

Applicant: UNIVERSITY HEALTH NETWORK ,  BECKMAN COULTER, INC.

Inventor： T. Vincent Shankey ,  Sergei Gulnik ,  Lidice L. Lopez ,  David W. Hedley ,  Sue Chow

IPC: G01N33/49 ,  G01N33/53 ,  G01N33/50 ,  C12Q1/37 ,  G01N33/58 ,  G01N15/14 ,  C07K14/47 ,  C07K16/18 ,  G01N15/00 ,  G01N15/10

CPC classification number: G01N33/5041 ,  C07K14/47 ,  C07K16/18 ,  C12Q1/37 ,  G01N15/14 ,  G01N33/4915 ,  G01N33/5011 ,  G01N33/5047 ,  G01N33/53 ,  G01N33/582 ,  G01N2015/008 ,  G01N2015/1006 ,  G01N2015/149 ,  G01N2333/4704 ,  G01N2440/14

Abstract: Assays that can measure the effect of proteasome inhibitors on target cells in a biological sample are provided. The assays include evaluation of the effects of proteasome inhibitors on proteasome activity in cells in a biological sample.