公开(公告)号：US11969505B2

公开(公告)日：2024-04-30

申请号：US17712732

申请日：2022-04-04

Applicant: UPM-KYMMENE CORPORATION

Inventor： Heli Paukkonen ,  Vili-Veli Auvinen ,  Marjo Yliperttula ,  Patrick Laurën ,  Arto Urtti ,  Timo Laaksonen ,  Arto Merivaara ,  Tiina Hakkarainen ,  Outi Monni ,  Anne Mäkelä ,  Petter Somersalo ,  Piia-Riitta Karhemo ,  Heikki Joensuu ,  Raili Koivuniemi ,  Kari Luukko ,  Markus Nuopponen

IPC: A01N1/02 ,  A61K9/06 ,  A61K9/19 ,  A61K47/10 ,  A61K47/26 ,  A61K47/38 ,  C12N5/00 ,  C12N5/09 ,  F26B5/06

CPC classification number: A61K9/19 ,  A01N1/0221 ,  A01N1/0231 ,  A61K9/06 ,  A61K47/10 ,  A61K47/26 ,  A61K47/38 ,  C12N5/0062 ,  C12N5/0693 ,  F26B5/06 ,  C12N2513/00 ,  C12N2533/78

Abstract: The present disclosure provides a method for freeze-drying cells in a hydrogel comprising nanofibrillar cellulose, the method comprising providing a hydrogel comprising nanofibrillar cellulose, providing cells, combining the cells and the hydrogel comprising nanofibrillar cellulose to form a cell system, and freeze drying the cell system to obtain dried cells in a hydrogel comprising nanofibrillar cellulose. The present disclosure also provides a freeze-dried hydrogel comprising nanofibrillar cellulose and cells.

公开(公告)号：US20220349651A1

公开(公告)日：2022-11-03

申请号：US17245445

申请日：2021-04-30

Applicant: UPM-Kymmene Corporation

Inventor： Markus Nuopponen ,  Marjo Yliperttula ,  Arto Merivaara ,  Ossi Korhonen ,  Jacopo Zini ,  Elle Koivunotko ,  Lisa Chinello ,  Giulia Scapin ,  Anne Meriluoto ,  Lauri Paasonen

IPC: F26B5/06 ,  C12N5/00

Abstract: A method for freeze-drying a hydrogel composition is disclosed, the method comprising providing the hydrogel composition, wherein the hydrogel composition comprises cellulose nanofibrils and/or cellulose nanocrystals, at least one saccharide, at least one amino acid, and biologics; and freeze-drying the hydrogel composition, thereby obtaining a freeze-dried hydrogel composition.

公开(公告)号：US11324701B2

公开(公告)日：2022-05-10

申请号：US16468390

申请日：2017-08-25

Applicant: UPM-KYMMENE CORPORATION

Inventor： Heli Paukkonen ,  Vili-Veli Auvinen ,  Marjo Yliperttula ,  Patrick Laurén ,  Arto Urtti ,  Timo Laaksonen ,  Arto Merivaara ,  Tiina Hakkarainen ,  Outi Monni ,  Anne Mäkelä ,  Petter Somersalo ,  Piia-Riitta Karhemo ,  Heikki Joensuu ,  Raili Koivuniemi ,  Kari Luukko ,  Markus Nuopponen

IPC: A61K9/19 ,  A61K47/10 ,  A61K47/26 ,  A61K47/38 ,  A01N1/02 ,  C12N5/00 ,  C12N5/09 ,  A61K9/06 ,  F26B5/06

Abstract: The present disclosure provides a method for freeze-drying cells in a hydrogel comprising nanofibrillar cellulose, the method comprising providing a hydrogel comprising nanofibrillar cellulose, providing cells, combining the cells and the hydrogel comprising nanofibrillar cellulose to form a cell system, and freeze drying the cell system to obtain dried cells in a hydrogel comprising nanofibrillar cellulose. The present disclosure also provides a freeze-dried hydrogel comprising nanofibrillar cellulose and cells.