公开(公告)号：US06639225B2

公开(公告)日：2003-10-28

申请号：US09951762

申请日：2001-09-14

申请人： Ulf-Carsten Kirschstein ,  Erik Beckert ,  Andrew Hoffmann ,  Christoph Schaeffel ,  Eugen Saffert ,  Johannes Zentner ,  Torsten Gramsch

发明人： Ulf-Carsten Kirschstein ,  Erik Beckert ,  Andrew Hoffmann ,  Christoph Schaeffel ,  Eugen Saffert ,  Johannes Zentner ,  Torsten Gramsch

IPC分类号： G21K510

CPC分类号： G03F7/707 ,  G03F7/70716 ,  H01J2237/202 ,  H01L21/68

摘要： The invention refers to an arrangement for positioning substrates, in particular for positioning wafers, within a device that is provided for exposure of the substrates and/or for measurement on the substrates by means of radiation under high-vacuum conditions. The following are provided according to the present invention: a retention system (4), displaceable on a linear guidance system (3), for receiving the substrate, the guidance direction of the linear guidance system (3) being oriented parallel or substantially parallel to the Y coordinate of an X, Y, Z spatial coordinate system; drives for limited modification of the inclination of the guidance direction relative to the Y coordinate; drives for limited rotation of the linear guidance system (3), including the retention system (4), about the guidance direction; and drives for parallel displacement of the linear guidance system (3), including the retention system (4), in the direction of the X coordinate, the Y coordinate, and/or the Z coordinate.

公开(公告)号：US20050054958A1

公开(公告)日：2005-03-10

申请号：US10902122

申请日：2004-07-30

申请人： Andrew Hoffmann

发明人： Andrew Hoffmann

IPC分类号： A61B17/22 ,  A61H1/00 ,  A61H23/00 ,  A61H23/02 ,  A61H31/00 ,  A61M5/00

CPC分类号： A61H31/005 ,  A61B17/225 ,  A61H1/00 ,  A61H31/00 ,  A61H31/006 ,  A61H2023/0209 ,  A61H2201/5043 ,  A61H2201/5061

摘要： An emergency system for treatment of a patient (20) experiencing an acute vascular obstruction, employing a non-invasive vibrator (10), optimally in conjunction with drugs, for disrupting and lysing thromboses, relieving spasm (if associated), and thereby restoring blood perfusion. Vibrator (10) is operable in the sonic to infrasonic range, with a source output of up to 15 mm. For acute myocardial infarction cases, a pair of contacts (12), are advantageously placed to bridge the sternum at the fourth intercostal space. Vibration is initiated at 50 Hz (or any frequency, preferably within the 20-120 Hz range), and is ideally adjusted to a maximal amplitude (or force) deemed tolerable and safe to the patient (20), preferably with the administration of thrombolytic agents or other form of drug therapy. A synergistic effect is achieved between vibration and drugs to facilitate the disruption of thromboses, relieve spasm, and restore blood perfusion. In a variation, ultrasonic imaging may be used to direct vibration therapy.

摘要翻译： 用于治疗经历急性血管阻塞的患者（20）的紧急系统，使用非侵入式振动器（10），最佳地与药物结合，用于破坏和溶解血栓形成，缓解痉挛（如果相关联），从而恢复血液 灌注。 振动器（10）可在声速到声速范围内操作，源输出高达15 mm。 对于急性心肌梗死病例，有利地放置一对触点（12）以在第四肋间隙处桥接胸骨。 振动以50Hz（或任何频率，优选在20-120Hz范围内）开始，并且理想地被调整为对患者（20）被认为是可容忍和安全的最大幅度（或力），优选地通过施用溶栓剂 药剂或其他形式的药物治疗。 在振动和药物之间实现协同效应，以促进血栓形成的破坏，缓解痉挛和恢复血液灌注。 在一个变型中，可以使用超声成像来引导振动治疗。

公开(公告)号：US20060025683A1

公开(公告)日：2006-02-02

申请号：US11036386

申请日：2005-01-18

申请人： Andrew Hoffmann

发明人： Andrew Hoffmann

IPC分类号： A61B8/12

CPC分类号： A61B8/08 ,  A61B8/0883 ,  A61B8/0891 ,  A61B8/4455 ,  A61B8/483 ,  A61N7/00

摘要： A non-invasive hand-held treatment imaging probe for treatment of acute blood flow disturbances and states of low blood perfusion. The treatment imaging probe is operable to emit high intensity therapeutic mechanical acoustic waves while under ultrasonic imaging guidance. The probe has a substantially rigid application surface, sized to enable seating within a rib space of a patient (i.e. for cardiac applications), comprising the combination of an engagement face of an ultrasonic imaging transducer and an application end of a high powered therapeutic actuator operable in about the 1-500 kHz (and preferably 1-150 kHz) range. Treatment imaging probe can be used as an adjunct to thrombolytic therapy in the treatment of acute thrombotic vascular obstructions, such as in acute myocardial infarction, or alternatively to enhance localized delivery of angiogenic agents or other useful medications to targeted vascular regions.

摘要翻译： 一种用于治疗急性血流紊乱和低血液灌注状态的非侵入式手持治疗成像探针。 治疗成像探针可操作以在超声成像引导下发射高强度治疗机械声波。 该探针具有基本上刚性的施加表面，其大小使得能够在患者的肋部空间（即，用于心脏应用）中安置，包括超声波成像换能器的接合面和高功率治疗致动器的施加端的组合，其可操作 在约1-500kHz（优选地1-150kHz）范围内。 治疗成像探针可用作治疗急性血栓形成血管阻塞物（例如急性心肌梗塞）中血栓溶解治疗的辅助剂，或者用于增强血管生成剂或其它有用的药物到靶向血管区域的局部递送。