Dialysis membrane of modified cellulose with improved biocompatibility
    1.
    发明授权
    Dialysis membrane of modified cellulose with improved biocompatibility 失效
    具有改善生物相容性的改性纤维素透析膜

    公开(公告)号:US4668396A

    公开(公告)日:1987-05-26

    申请号:US765530

    申请日:1985-08-14

    CPC分类号: C08B11/00 B01D71/22

    摘要: A dialysis membrane used for hemodialysis having a structure comprised of flat films, blown films or tubular threads of substitution-modified cellulose, in which the effects of complement activation and leukopenia are clearly reduced. The average degree of substitution of the modified cellulose is 0.02 to 0.07. Dialysis membranes, which have proven successful within the scope of the invention, contain modified cellulose, having a structure represented by the formula cellulose-Z, wherein Z represents the group --R'--X--Y.X is at least one member selected from the group consisting of ##STR1## Y is at least one member selected from the group consisting of --R, --NR.sub.2, --Si(OR").sub.3, --SO.sub.3 H, --COOH, --PO.sub.3 H.sub.2, --N.sup.+ HR.sub.2, --OR" and the salts thereof.R' is at least one member selected from the group consisting of an alkylenes cycloalkylenes and arylenes having a total of 1 to 25 carbon atoms.R" is a hydrogen atom or R.R is at least one member selected from the group consisting of an alkyls with 1 to 5 carbon atoms, cycloalkyls and an aryls.

    摘要翻译: 用于血液透析的透析膜具有包含补体活化和白细胞减少的效果的取代改性纤维素的平膜,吹膜或管状线构成的结构。 改性纤维素的平均取代度为0.02〜0.07。 已经证明在本发明范围内成功的透析膜含有具有式Z-基团-R'-X-Y所示结构式纤维素-Z的改性纤维素。 X是从由以下组成的组中选择的至少一个成员:Y是至少一个选自-R,-NR2,-Si(OR“)3,-SO3H, -COOH,-PO 3 H 2,-N + HR 2,-OR“及其盐。 R'是选自具有总共1至25个碳原子的亚烷基环烷烃和亚芳基中的至少一种。 R“是氢原子或R.R是选自具有1至5个碳原子的烷基,环烷基和芳基中的至少一个。

    Process for producing extractive-material-reduced cellulose
    3.
    发明授权
    Process for producing extractive-material-reduced cellulose 失效
    生产萃取材料减少纤维素的方法

    公开(公告)号:US4814440A

    公开(公告)日:1989-03-21

    申请号:US103345

    申请日:1987-10-01

    摘要: The invention relates to a process for obtaining extractive-material-reduced cellulose with a low LAL reaction, wherein cotton linters or wood pulps, subsequent to the customary digesting treatment, are subjected for 1 to 10 hours to hydraulic washing with water, lye with a concentration of less than 5 g/l alkali content, or with a diluted acid containing less than 5 g/l acid at temperatures of 120.degree. to 180.degree. C. and under a pressure of 2 to 20 bar.The resulting cellulose is used for the manufacture of hemodialysis and/or hemofiltration membranes in the form of flat membranes, tubular membranes or hollow filaments by regeneration of a cellulose solution containing the extractive-material-reduced cellulose with a low LAL reaction.The regeneration may be effected from solutions of cellulose cuoxam, cellulose xanthate, or solutions of cellulose in tertiary amine oxide or in an LiCl-containing solvent.

    摘要翻译: 本发明涉及一种获得具有低LAL反应的萃取材料还原的纤维素的方法,其中在常规消化处理之后将棉绒或木浆进行1至10小时以水洗液体,碱 浓度小于5g / l碱含量,或在120℃至180℃的温度和2至20巴的压力下,使用含有少于5g / l酸的稀酸。 所得到的纤维素用于通过用低LAL反应再生含有萃取材料还原的纤维素的纤维素溶液来制造平膜,管状膜或中空细丝形式的血液透析和/或血液滤过膜。 再生可以由纤维素cuoxam,黄原酸纤维素或纤维素在叔胺氧化物溶液中或在含LiCl的溶剂中的溶液进行。

    Cellulose dialysis membrane with improved biocompatibility
    4.
    发明授权
    Cellulose dialysis membrane with improved biocompatibility 失效
    纤维素透析膜具有改善的生物相容性

    公开(公告)号:US4772393A

    公开(公告)日:1988-09-20

    申请号:US81534

    申请日:1987-08-04

    CPC分类号: B01D71/10 B01D71/12

    摘要: The invention relates to a dialysis membrane of regenerated cellulose and to a process for its production. Isocyanate prepolymers with an average molecular weight of 300 to 50,000, which are soluble in organic solvents other than solvents reacting with isocyanate groups and dissolving cellulose, are bound chemically at least to one membrane surface of the dialysis membrane. The dialysis membrane of the present invention substantially eliminates the symptoms of leukopenia and complement activation.

    摘要翻译: 本发明涉及再生纤维素的透析膜及其生产方法。 平均分子量为300〜50,000的异氰酸酯预聚物,其可溶于与异氰酸酯基反应的溶剂和溶解纤维素以外的有机溶剂中,化学键合在透析膜的至少一个膜表面。 本发明的透析膜基本上消除了白细胞减少症和补体激活的症状。

    Production of cellulose dialysis membrane with improved biocompatibility
    5.
    发明授权
    Production of cellulose dialysis membrane with improved biocompatibility 失效
    纤维素透析膜的生产具有改善的生物相容性

    公开(公告)号:US4741927A

    公开(公告)日:1988-05-03

    申请号:US871761

    申请日:1986-05-16

    CPC分类号: B01D71/10 B01D71/12

    摘要: The invention relates to a method for the production of a dialysis membrane of regenerated cellulose. Isocyanate prepolymers with an average molecular weight of 300 to 50,000, which are soluble in organic solvents other than solvents reacting with isocyanate groups and dissolving cellulose, are bound chemically at least to one membrane surface of the dialysis membrane. The dialysis membrane made by the process of the present invention substantially eliminates the symptoms of leukopenia and complement activation.

    摘要翻译: 本发明涉及生产再生纤维素透析膜的方法。 平均分子量为300〜50,000的异氰酸酯预聚物,其可溶于与异氰酸酯基反应的溶剂和溶解纤维素以外的有机溶剂中,化学键合在透析膜的至少一个膜表面。 通过本发明的方法制备的透析膜基本上消除了白细胞减少症和补体激活的症状。

    Embedding mass of polyurethane
    6.
    发明授权
    Embedding mass of polyurethane 失效
    嵌入聚氨酯的质量

    公开(公告)号:US4391964A

    公开(公告)日:1983-07-05

    申请号:US351140

    申请日:1982-02-22

    摘要: Embedding mass of polyurethane produced on the basis of castor oil, and a method for its production, wherein an aromatic diisocyanate is reacted with a mixture of castor oil and trimethylolpropane into an NCO-group displaying pre-adduct, the pre-adduct being mixed for network polymerization with castor oil or a mixture of castor oil and trimethylolpropane, and after embedding the mixture is hardened in the presence of catalyst, thereby characterized in that a titanium alkylate compound is used as catalyst in amounts from 7 to 700 ppm, calculated as elemental titanium. Preferably, the catalyst is a titanium tetraalkylate; in particular titanium tetrabutylate. Also, a titanium magnesium hexaalkylate may be used as titanium alkylate compound; preferably, titanium magnesium hexabutylate. Preferably the catalyst is present in amounts from 40 to 140 ppm, calculated as elemental titanium. The embedding mass may be used for the embedding of membranes, particularly in artificial organs, especially in the form of hollow filaments, tube foils or flat foils. They may be used for selectively working dialysators, including selectively working hemodialysators, and other arrangements for the detoxification of blood. The embedding is performed according to the casting process, preferably the centrifuge casting process.

    摘要翻译: 基于蓖麻油生产的聚氨酯的嵌入质量及其制备方法,其中将芳族二异氰酸酯与蓖麻油和三羟甲基丙烷的混合物反应成显示预加合物的NCO-基团,将前加合物混合 用蓖麻油或蓖麻油和三羟甲基丙烷的混合物进行网络聚合,并且在包埋之后,在催化剂存在下将混合物硬化,其特征在于使用烷基钛化合物作为催化剂,其量为7至700ppm,以元素计算 钛。 优选地,催化剂是四烷基钛酸盐; 特别是四丁基钛。 此外,六烷基钛镁镁可以用作烷基化钛化合物; 优选钛酸镁六丁基锡。 催化剂优选以40-140ppm的量存在,以元素钛计算。 嵌入质量可以用于包埋膜,特别是在人造器官中,特别是中空丝,管箔或平箔的形式。 它们可用于选择性地加工透析器,包括选择性地加工血液透析器,以及用于解毒血液的其它安排。 根据铸造工艺,优选离心铸造工艺进行嵌入。

    Device for the protection of a converter which converts an impressed D-C
current from a current source into an A-C current fed to a load
    7.
    发明授权
    Device for the protection of a converter which converts an impressed D-C current from a current source into an A-C current fed to a load 失效
    用于保护转换器的装置,其将来自电流源的外加D-C电流转换为馈送到负载的A-C电流

    公开(公告)号:US4369492A

    公开(公告)日:1983-01-18

    申请号:US244123

    申请日:1981-03-16

    IPC分类号: H02H7/122 H02H7/127

    CPC分类号: H02H7/127 H02H7/1225

    摘要: The converter protection device has a number of controlled semiconductor elements. A control unit is connected to the semiconductor elements of the converter for forming firing pulses for the controlled semiconductor elements. Reference blocking intervals for the semiconductor elements are set and actual blocking intervals of the semiconductor elements are set and controlled. A comparator receives and compares the reference and actual blocking intervals. There are also provided a read-only memory for storing the reference blocking intervals, an event counter for counting disturbances detected by comparison of the reference and actual blocking intervals, a memory stage being connected to the event counter and being set if the event counter reaches a predetermined count, and a time-base device connected to the event counter and memory stage for resetting the event counter if the memory stage is not set at the end of a predetermined base time.

    摘要翻译: 转换器保护装置具有多个受控的半导体元件。 控制单元连接到用于形成用于受控半导体元件的点火脉冲的转换器的半导体元件。 设置用于半导体元件的参考阻挡间隔,并且设置和控制半导体元件的实际阻挡间隔。 比较器接收并比较参考和实际阻塞间隔。 还提供了用于存储参考阻塞间隔的只读存储器,用于对参考和实际阻塞间隔进行比较而检测到的扰动进行计数的事件计数器,连接到事件计数器的存储器级,如果事件计数器到达则被设置 如果在预定基准时间结束时没有设置存储器级,则连接到事件计数器和存储器级的时基设备用于复位事件计数器。

    Method and circuit arrangement for controlling an asynchronous motor
supplied from a static frequency changer
    8.
    发明授权
    Method and circuit arrangement for controlling an asynchronous motor supplied from a static frequency changer 失效
    用于控制从静态变频器提供的异步电动机的方法和电路装置

    公开(公告)号:US4263542A

    公开(公告)日:1981-04-21

    申请号:US963990

    申请日:1978-11-27

    IPC分类号: H02P23/08 H02P5/40

    CPC分类号: H02P23/08

    摘要: Method for controlling the speed and torque of an asynchronous machine fed through a static frequency changer with impressed intermediate current link, a control variable for the frequency of the current delivered by the frequency changer being formed from an electrical variable corresponding to a slip frequency value and an electrical variable corresponding to actual value of a frequency proportional to the rotor speed of the asynchronous machine which includes operating the asynchronous machine with constant flux in a region of constant maximal torque, and adjusting the flux in the machine, in a region of constant maximal power, as a function both of voltage at commutating capacitors of a self-commutating inverter and of a respective load condition of the asynchronous machine.

    摘要翻译: 用于控制通过具有外加中间电流链路的静态变频器馈送的异步电机的速度和转矩的方法,由变频器传送的电流的频率的控制变量由对应于转差频率值的电变量形成,以及 对应于与异步电机的转子转速成比例的频率的实际值的电变量,其包括在恒定最大扭矩的区域中操作具有恒定通量的异步电机,并且在恒定最大值的区域中调节机器中的通量 电力,作为自换向变换器的换向电容器的电压以及异步电机的相应负载条件的功能。