公开(公告)号：US20180194890A1

公开(公告)日：2018-07-12

申请号：US15742266

申请日：2016-06-30

申请人： Universiteit Gent ,  Allnex Belgium SA

发明人： Peter DUBRUEL ,  Sandra VAN VLIERBERGHE ,  Annemie HOUBEN ,  Hugues VAN DEN BERGEN ,  Patrice ROOSE ,  Dirk BONTINCK

IPC分类号： C08G18/75 ,  C08G18/67 ,  C08G18/48 ,  C08G18/42 ,  C08G18/10 ,  C08J3/24 ,  C08J3/28 ,  C09D175/16 ,  D01D5/00 ,  D01F11/08

CPC分类号： C08G18/755 ,  C08G18/10 ,  C08G18/4277 ,  C08G18/4833 ,  C08G18/672 ,  C08G18/6725 ,  C08G18/673 ,  C08J3/24 ,  C08J3/28 ,  C09D175/16 ,  D01D5/0015 ,  D01F11/08 ,  D10B2401/02 ,  C08G18/48

摘要： The invention pertains to the technical field of urethane based materials, in particular to radiation curable urethane precursors that are cross-linkable in solid form and materials obtainable therefrom. In addition the invention pertains to methods for manufacturing these precursors and materials, and their uses. The invention is advantageous to the fields of i.e. coatings and biomedical applications.

公开(公告)号：US20130245606A1

公开(公告)日：2013-09-19

申请号：US13832069

申请日：2013-03-15

申请人： UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK ,  INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM VZW ,  KATHOLIEKE UNVIVERSITEIT LEUVEN - KU LEUVEN RESEARCH & DEVELOPMENT ,  UNIVERSITEIT GENT ,  RAMOT AT TEL-AVIV UNIVERSITY, LTD. ,  TECHNISCHE UNIVERSITEIT DELFT

发明人： Frank Albert STAM ,  Nathan JACKSON ,  Peter DUBRUEL ,  Kehinde ADESANYA ,  Anika EMBRECHTS ,  Eduardo MENDES, JR. ,  Hurcules Pereira NEVES ,  Paul HERIJGERS ,  Peter VERBRUGGHE ,  Yosi SHACHAM ,  Leeya ENGEL ,  Viacheslav KRYLOV

IPC分类号： A61B17/12

CPC分类号： A61B17/12109 ,  A61B17/12122 ,  A61B17/12181 ,  A61B17/1219 ,  A61B90/361 ,  A61B2017/1205 ,  A61B2090/061

摘要： A hydrogel based occlusion system, a method for occluding vessels, appendages or aneurysms, and a method for hydrogel synthesis are disclosed. The hydrogel based occlusion system includes a hydrogel having a shrunken and a swollen state and a delivery tool configured to deliver the hydrogel to a target occlusion location. The hydrogel is configured to permanently occlude the target occlusion location in the swollen state. The hydrogel may be an electro-activated hydrogel (EAH) which could be electro-activated with a delivery system to control the degree of swelling/shrinking.

摘要翻译： 公开了一种基于水凝胶的闭塞系统，闭塞血管，附属物或动脉瘤的方法以及水凝胶合成方法。 基于水凝胶的闭塞系统包括具有收缩和膨胀状态的水凝胶和被配置为将水凝胶递送到目标闭塞位置的递送工具。 水凝胶被配置为在肿胀状态下永久闭塞目标闭塞位置。 水凝胶可以是电活化水凝胶（EAH），其可以用递送系统电活化以控制膨胀/收缩的程度。

公开(公告)号：US20190031824A1

公开(公告)日：2019-01-31

申请号：US16082844

申请日：2017-03-23

申请人： UNIVERSITEIT GENT

发明人： Elena Diana GIOL ,  Peter DUBRUEL ,  Sandra VAN VLIERBERGHE

IPC分类号： C08G63/183 ,  C12N5/071 ,  A61L27/50 ,  A61L27/58 ,  A61L27/54 ,  A61L27/38 ,  A61L27/18 ,  C08G63/81 ,  C12N5/00

摘要： The present invention relates to poly(alkylene terephthalate) polyesters having long poly-methylene segments and their use in a wide variety of applications. Particularly, said PAT polyesters are used in biotechnological or biomedical applications, wherein the extent of cell adhesion, cell growth or cell interaction, in particular endothelial cells, depends on the odd or even number of carbon atoms in the aliphatic segments. Also provided are methods for the preparation of poly(alkylene terephthalates) (PAT) having long poly-methylene segments, wherein the bifunctional monomers, in particular terephthalic acid (or a derivative thereof) and an aliphatic diol, are dissolved in a solvent and the polycondensation reaction takes place in solution.

公开(公告)号：US20240060216A1

公开(公告)日：2024-02-22

申请号：US17641210

申请日：2020-09-11

申请人： UNIVERSITEIT GENT

发明人： Arn MIGNON ,  Tom GHEYSENS ,  Sandra VAN VLIERBERGHE ,  Peter DUBRUEL

IPC分类号： D01F6/70 ,  D01F1/10

CPC分类号： D01F6/70 ,  D01F1/103 ,  D01D5/003

摘要： Fibrous materials are provided that comprise a cross-linkable urethane-based polymer (CUP) and an oligomeric or macromonomeric urethane-based cross-linker. The fibrous materials may be used in hydrogels, in filtration devices, in affinity membranes, in (protective) clothing, in drug delivery systems, and in tissue scaffolds, for example. The fibrous materials are useable also in human and/or veterinary medicine, such as in skin care and/or wound care.

公开(公告)号：US20220325030A1

公开(公告)日：2022-10-13

申请号：US17640518

申请日：2020-09-11

申请人： UNIVERSITEIT GENT

发明人： Arn Mignon ,  Tom GHEYSENS ,  Sandra VAN VLIERBERGHE ,  Peter DUBRUEL

IPC分类号： C08G18/75 ,  C08G18/48 ,  C08F290/06 ,  A61L26/00 ,  C08K5/00 ,  C08J3/075

摘要： Hydrogels are provided that include an antimicrobial agent and a cross-linkable urethane-based polymer (CUP). Such hydrogels may be used for the controlled-release of antimicrobial agents as well as in the manufacturing of wound dressings. Wound dressings are provided that comprise a hydrogel as defined herein.