公开(公告)号：US20190247542A1

公开(公告)日：2019-08-15

申请号：US16274047

申请日：2019-02-12

Applicant: University of Southampton

Inventor： Richard Oreffo ,  Jonathan Dawson ,  David Gibbs ,  Jons Hilborn ,  Dmitri Ossipov

IPC: A61L27/44 ,  A61L27/54 ,  A61K47/02 ,  C08K3/34 ,  A61K38/18 ,  C08J3/075 ,  A61L27/52

CPC classification number: A61L27/446 ,  A61K38/1875 ,  A61K47/02 ,  A61L27/52 ,  A61L27/54 ,  A61L2300/414 ,  A61L2300/64 ,  A61L2400/12 ,  A61L2430/02 ,  C08J3/075 ,  C08J2305/08 ,  C08K3/346 ,  C08K2201/006 ,  C08L5/08

Abstract: The invention relates to a polymer-clay composite material comprising clay nanoparticles and a polymer, and wherein (a) the polymer comprises phosphate and/or phosphonate ligands; or (b) the polymer-clay composite further comprises linker molecules comprising a phosphate or phosphonate ligand, wherein the linker molecules are arranged to be anchored to the polymer. The invention further relates to organoclays, BMP-clay composite material. Uses, treatments, and manufacturer of the material are also provided.

公开(公告)号：US11173230B2

公开(公告)日：2021-11-16

申请号：US16274047

申请日：2019-02-12

Applicant: University of Southampton

Inventor： Richard Oreffo ,  Jonathan Dawson ,  David Gibbs ,  Jons Hilborn ,  Dmitri Ossipov

IPC: C08K3/34 ,  A61L27/44 ,  A61L27/52 ,  A61L27/54 ,  C08J3/075 ,  A61K38/18 ,  A61K47/02

Abstract: The invention relates to a polymer-clay composite material comprising clay nanoparticles and a polymer, and wherein (a) the polymer comprises phosphate and/or phosphonate ligands; or (b) the polymer-clay composite further comprises linker molecules comprising a phosphate or phosphonate ligand, wherein the linker molecules are arranged to be anchored to the polymer. The invention further relates to organoclays, BMP-clay composite material. Uses, treatments, and manufacturer of the material are also provided.

公开(公告)号：US20220096715A1

公开(公告)日：2022-03-31

申请号：US17277690

申请日：2019-09-20

Applicant: UNIVERSITY OF SOUTHAMPTON

Inventor： Richard Oreffo ,  Jonathan Dawson ,  Nicolas Evans ,  Roxanna Sharon Ramnarine Sanchez

IPC: A61L27/44 ,  A61K38/18 ,  A61K38/17 ,  A61K31/4188 ,  A61K38/16 ,  C07K16/28 ,  A61L27/54

Abstract: The invention relates to a method for assembling a clay-nanoparticle gel suitable for loading with one or more molecule species such that they are spatially structured therein, and a method for forming a clay-nanoparticle gel comprising one or more spatially structured molecule species. The invention further relates to structured clay nanoparticle gel and their use, for example in treatment.

公开(公告)号：US10245350B2

公开(公告)日：2019-04-02

申请号：US15306020

申请日：2015-04-24

Applicant: University of Southampton

Inventor： Richard Oreffo ,  Jonathan Dawson ,  David Gibbs ,  Jons Hilborn ,  Dmitri Ossipov

IPC: C08K3/34 ,  A61L27/44 ,  A61L27/52 ,  A61L27/54 ,  C08J3/075 ,  A61K38/18 ,  A61K47/02

Abstract: The invention relates to a polymer-clay composite material comprising clay nanoparticles and a polymer, and wherein (a) the polymer comprises phosphate and/or phosphonate ligands; or (b) the polymer-clay composite further comprises linker molecules comprising a phosphate or phosphonate ligand, wherein the linker molecules are arranged to be anchored to the polymer. The invention further relates to organoclays, BMP-clay composite material. Uses, treatments, and manufacturer of the material are also provided.