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公开(公告)号：US20200005960A1
公开(公告)日：2020-01-02
申请号：US16309795
申请日：2017-06-13
发明人： Daniel T. CHIU , Jiangbo YU , Yu RONG , Changfeng WU
摘要： The present disclosure provides organic-inorganic hybrid polymer particles, which have desirable surface chemistry and optical properties that make them particularly suitable for biological and optical applications. The present disclosure also provides methods of making organic-inorganic hybrid polymer particles. The present disclosure also provides methods of using the organic-inorganic hybrid polymer particles for biological and optical applications.
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公开(公告)号：US20190004056A1
公开(公告)日：2019-01-03
申请号：US16041569
申请日：2018-07-20
发明人： Daniel T. CHIU , Yuhui JIN , Fangmao YE , Changfeng WU , Yang-Hsiang CHAN
摘要： Polymer nanoparticles and related methods are provided. The polymer particles can include polymer dots having a coating including a polyelectrolyte polymer. Methods of making and using the polymer nanoparticles are also provided.
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公开(公告)号：US20240047098A1
公开(公告)日：2024-02-08
申请号：US18484587
申请日：2023-10-11
发明人： Daniel T. CHIU , Jiangbo YU , Yu RONG , Changfeng WU
CPC分类号： H01B1/18 , C07K14/00 , C07K16/00 , C08K3/36 , C08L83/04 , G02F1/015 , C08K2201/001 , C08L2203/20
摘要： The present disclosure provides organic-inorganic hybrid polymer particles, which have desirable surface chemistry and optical properties that make them particularly suitable for biological and optical applications. The present disclosure also provides methods of making organic-inorganic hybrid polymer particles. The present disclosure also provides methods of using the organic-inorganic hybrid polymer particles for biological and optical applications.
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公开(公告)号：US20200312481A1
公开(公告)日：2020-10-01
申请号：US16900809
申请日：2020-06-12
发明人： Daniel T. CHIU , Jiangbo YU , Yu RONG , Changfeng WU
摘要： The present disclosure provides organic-inorganic hybrid polymer particles, which have desirable surface chemistry and optical properties that make them particularly suitable for biological and optical applications. The present disclosure also provides methods of making organic-inorganic hybrid polymer particles. The present disclosure also provides methods of using the organic-inorganic hybrid polymer particles for biological and optical applications.
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公开(公告)号：US20160018395A1
公开(公告)日：2016-01-21
申请号：US14774971
申请日：2014-03-14
发明人： Daniel T. CHIU , Wei SUN , Jiangbo YU , Changfeng WU , Fangmao YE
IPC分类号： G01N33/543 , C08G73/00 , C08G75/32 , C08G61/02 , G01N33/533 , G01N33/58
摘要： Lyophilized chromophoric polymer dot compositions are provided. Also disclosed are methods of making and using the lyophilized compositions, methods of dispersing the lyophilized compositions in aqueous solutions and kits supplying the compositions.
摘要翻译： 提供了冻干的发色聚合物点组合物。 还公开了制备和使用冻干组合物的方法，将冻干组合物分散在水溶液中的方法和提供组合物的试剂盒。
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公开(公告)号：US20210343445A1
公开(公告)日：2021-11-04
申请号：US17368078
申请日：2021-07-06
发明人： Daniel T. CHIU , Jiangbo YU , Yu RONG , Changfeng WU
摘要： The present disclosure provides organic-inorganic hybrid polymer particles, which have desirable surface chemistry and optical properties that make them particularly suitable for biological and optical applications. The present disclosure also provides methods of making organic-inorganic hybrid polymer particles. The present disclosure also provides methods of using the organic-inorganic hybrid polymer particles for biological and optical applications.
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公开(公告)号：US20200158724A1
公开(公告)日：2020-05-21
申请号：US16702228
申请日：2019-12-03
发明人： Daniel T. CHIU , Wei SUN , Jiangbo YU , Changfeng WU , Fangmao YE
IPC分类号： G01N33/543 , G01N33/58 , C09K11/02 , C08G61/02 , C08G73/00 , C08G75/32 , G01N33/533
摘要： Lyophilized chromophoric polymer dot compositions are provided. Also disclosed are methods of making and using the lyophilized compositions, methods of dispersing the lyophilized compositions in aqueous solutions and kits supplying the compositions.
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公开(公告)号：US20190234953A1
公开(公告)日：2019-08-01
申请号：US16209729
申请日：2018-12-04
发明人： Daniel T. CHIU , Changfeng WU , Jason MCNEILL , Jiangbo YU
CPC分类号： G01N33/587 , C09K11/06 , G01N33/582
摘要： The present invention provides, among other aspects, functionalized chromophoric polymer dots comprising a hydrophobic core and a hydrophilic cap, and bioconjugates thereof. Also provided are improved methods for preparing functionalized chromophoric polymer dots. Methods for in vivo imaging and molecular labeling are also disclosed.
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公开(公告)号：US20190106542A1
公开(公告)日：2019-04-11
申请号：US16138732
申请日：2018-09-21
发明人： Daniel T. CHIU , Changfeng WU , Yu RONG , Yong ZHANG , Yi-Che WU , Yang-Hsiang CHAN , Xuanjun ZHANG , Jiangbo YU , Wei SUN
摘要： Polymers, monomers, chromophoric polymer dots and related methods are provided. Highly fluorescent chromophoric polymer dots with narrow-band emissions are provided. Methods for synthesizing the chromophoric polymers, preparation methods for forming the chromophoric polymer dots, and biological applications using the unique properties of narrow-band emissions are also provided.
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