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    Methods and devices for treating vulnerable plaque
    4.
    发明申请
    Methods and devices for treating vulnerable plaque 有权
    治疗易损斑块的方法和装置

    公开(公告)号：US20070123839A1

    公开(公告)日：2007-05-31

    申请号：US11290780

    申请日：2005-11-30

    申请人： Robert Rousseau ,  Kevin Weadock

    发明人： Robert Rousseau ,  Kevin Weadock

    IPC分类号： A61N1/30

    CPC分类号： A61B17/22 ,  A61B17/00491 ,  A61B17/12022 ,  A61B17/12136 ,  A61B17/12181 ,  A61B2017/00893 ,  A61B2017/22082 ,  A61M25/1002

    摘要： This invention provides methods, devices and kits for treating coronary artery disease, particularly “soft” or vulnerable plaque. The invention is based on the local delivery of crosslinking means to crosslink the collagen covering the plaque and other proteins that may be present at the site to stabilize the plaque and prevent leakage of thrombogenic material into the lumen of the coronary artery. In certain embodiments, catheters are employed to achieve local delivery of a crosslinking agent or ultraviolet light.

    摘要翻译： 本发明提供用于治疗冠状动脉疾病，特别是“软”或易损斑块的方法，装置和试剂盒。 本发明基于交联手段的局部递送，以交联覆盖斑块的胶原和可能存在于该部位的其它蛋白质以稳定斑块并防止血栓形成物质渗入冠状动脉的内腔。 在某些实施方案中，导管用于实现交联剂或紫外线的局部递送。

    Sternal closure device and method
    5.
    发明申请
    Sternal closure device and method 有权
    胸围闭合装置及方法

    公开(公告)号：US20050240189A1

    公开(公告)日：2005-10-27

    申请号：US10830122

    申请日：2004-04-22

    申请人： Robert Rousseau ,  Kevin Weadock ,  Etan Chatlynne

    发明人： Robert Rousseau ,  Kevin Weadock ,  Etan Chatlynne

    IPC分类号： A61B17/56 ,  A61B17/68 ,  A61B17/82

    CPC分类号： A61B17/683 ,  A61B17/823

    摘要： A device and method for joining a severed sternum is disclosed. The device includes first and second bearing members, a sternum joining member having an axis and first and second ends, the first end connected to the first bearing member, the second bearing member adapted to engage the sternum joining member, and the sternum joining member is adapted to traverse the exposed cancellous surfaces of the sternal portions. The method includes moving the second bearing member along the axis of the sternum joining member toward the first bearing member, with the sternum joining member traversing the cancellous surfaces of both sternal portions, and securing the second bearing member on the axis of the sternum joining member so that the severed sternum is securely closed. A kit including sternal closure devices and other tools for closing a sternotomy is also disclosed.

    摘要翻译： 公开了一种用于连接切断的胸骨的装置和方法。 该装置包括第一和第二轴承构件，具有轴线的胸骨连接构件和第一和第二端，第一端连接到第一轴承构件，第二轴承构件适于接合胸骨接合构件，并且胸骨接合构件是 适于穿过胸骨部分的暴露的松质骨表面。 所述方法包括使所述第二支承构件沿着所述胸骨接合构件的轴线朝向所述第一轴承构件移动，所述胸骨接合构件横穿所述两个胸骨部的松质面，并且将所述第二轴承构件固定在所述胸骨接合构件的轴线上 使得切断的胸骨牢固地关闭。 还公开了一种包括胸骨闭合装置和用于闭合胸骨切开术的其它工具的套件。

    Web function blocks capable of exchanging HTTP type of messages in automation equipment
    8.
    发明授权
    Web function blocks capable of exchanging HTTP type of messages in automation equipment 有权
    Web功能块能够在自动化设备中交换HTTP类型的消息

    公开(公告)号：US06915330B2

    公开(公告)日：2005-07-05

    申请号：US09893662

    申请日：2001-06-29

    申请人： Christian Hardy ,  Christophe Vincent ,  Jean-Marie Stawikowski ,  Robert Rousseau

    发明人： Christian Hardy ,  Christophe Vincent ,  Jean-Marie Stawikowski ,  Robert Rousseau

    IPC分类号： H04L29/06 ,  H04L29/08 ,  G06F15/16

    CPC分类号： H04L41/0253 ,  H04L29/06 ,  H04L67/02 ,  H04L67/12 ,  H04L69/329

    摘要： A communication system for automation equipment on a TCP/IP network. The automation equipment controls an automation application by executing an application program written according to standard IEC1131-3. The communication system includes at least a reception WEB function block integrated into the application program to implement a WEB server function, and/or at least one send WEB function block integrated into the application program to implement a WEB client function, and an HTTP interface capable of routing messages between the TCP/IP network and WEB function blocks identified by a URL address. The contents of HTTP requests may be an XML frame or a UEL encoded frame.

    摘要翻译： 一种用于TCP / IP网络上自动化设备的通信系统。 自动化设备通过执行根据标准IEC1131-3编写的应用程序来控制自动化应用。 通信系统至少包括集成到应用程序中以实现WEB服务器功能的接收WEB功能块和/或至少一个发送集成到应用程序中的WEB功能块以实现WEB客户端功能，以及能够 在TCP / IP网络和由URL地址标识的WEB功能块之间路由消息。 HTTP请求的内容可以是XML帧或UEL编码帧。

    Surgical wound closure device
    9.
    发明申请
    Surgical wound closure device 有权
    手术伤口闭合装置

    公开(公告)号：US20050034732A1

    公开(公告)日：2005-02-17

    申请号：US10830948

    申请日：2004-04-23

    申请人： Robert Rousseau ,  An-Min Sung

    发明人： Robert Rousseau ,  An-Min Sung

    IPC分类号： A61B17/08 ,  A61B19/08 ,  A61F13/00 ,  A61F13/02 ,  A61B19/00 ,  A61F5/37

    CPC分类号： A61F13/023 ,  A61B17/085 ,  A61F13/0206 ,  A61F13/0209 ,  A61F13/022 ,  A61F13/0223 ,  A61F13/0259 ,  A61F2013/0057

    摘要： One embodiment includes a surgical wound closure device comprising a substrate having a proximal surface and a distal surface; a drape having a proximal surface and a distal surface, and being disposed proximally to said substrate; and an adhesive layer having a proximal surface and a distal surface; said drape being disposed releasably adherently to said distal surface of said adhesive layer. Another embodiment includes a surgical procedure comprising the steps of providing a surgical wound closure device comprising a substrate having a proximal surface and a distal surface, a drape having a proximal surface and a distal surface and being disposed proximally to said substrate, and an adhesive layer having a proximal surface and a distal surface, where said drape being disposed releasably adherently to said distal surface of said adhesive layer; positioning the proximal surface of said adhesive layer on the skin of a patient; separating said substrate from said drape and adhesive layer to expose said distal surface of said drape; making a surgical incision through said drape; performing a surgical procedure; removing said drape from said adhesive layer to expose said distal surface of said adhesive layer; aligning said substrate and said adhesive layer; and adhering said proximal surface of said substrate to said distal surface of said adhesive layer.

    摘要翻译： 一个实施例包括外科伤口闭合装置，其包括具有近端表面和远侧表面的基底; 具有近侧表面和远侧表面的盖布，并且被布置在所述基底的近侧; 以及具有近端表面和远侧表面的粘合剂层; 所述盖布可剥离地贴合在所述粘合剂层的所述远端表面上。 另一个实施方案包括一种外科手术方法，其包括提供包括具有近端表面和远侧表面的基底的外科伤口闭合装置，具有近端表面和远端表面的盖布，并且邻近所述基底设置的粘合剂层 具有近端表面和远侧表面，其中所述盖布可剥离地设置在所述粘合剂层的所述远侧表面上; 将所述粘合剂层的近侧表面定位在患者的皮肤上; 将所述基底与所述覆盖层和粘合剂层分离以暴露所述盖布的所述远侧表面; 通过悬垂手术切口; 执行外科手术; 从所述粘合剂层去除所述盖布，以暴露所述粘合剂层的所述远侧表面; 对准所述基底和所述粘合剂层; 以及将所述基底的所述近端表面粘附到所述粘合剂层的所述远侧表面。

    Method of separating components in a biological fluid
    10.
    发明授权
    Method of separating components in a biological fluid 失效
    在生物流体中分离组分的方法

    公开(公告)号：US4158547A

    公开(公告)日：1979-06-19

    申请号：US695311

    申请日：1976-06-11

    申请人： Robert Rousseau ,  Charles A. Manganaro

    发明人： Robert Rousseau ,  Charles A. Manganaro

    IPC分类号： G01N33/50 ,  G01N33/78 ,  G01N33/16

    CPC分类号： G01N33/50 ,  G01N33/78 ,  Y10S436/804 ,  Y10S436/825 ,  Y10S436/826

    摘要： Insolubilized serum protein adsorbent, for example bovine serum albumin, of small particle size is an excellent adsorbent for adsorbable components in a biological fluid such as serum. Macroaggregated and polymerized albumin are particularly suited as adsorbents for unbound thyroid hormone in serum and can be used in diagnostic kits for determining total T.sub.4 and for T.sub.3 uptake.

    摘要翻译： 不溶解的血清蛋白质吸附剂，例如小粒径的血清白蛋白，是生物液体如血清中可吸附组分的优良吸附剂。 大量聚集和聚合的白蛋白特别适用于血清中未结合甲状腺激素的吸附剂，可用于诊断试剂盒，用于测定总T4和T3摄取。