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1.发明申请Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements 有权乙酰氨基酸作为抗血小板剂，营养和维生素补充剂公开(公告)号：US20110275713A1
公开(公告)日：2011-11-10
申请号：US13183013
申请日：2011-07-14
申请人： V. Ravi Chandran
发明人： V. Ravi Chandran
IPC分类号： A61K31/225 , A61P9/10 , A61P9/00
CPC分类号： A61K31/40 , A23L2/52 , A23L33/175 , A23V2002/00 , A61K31/198 , A61K31/22 , A61K31/221 , A61K31/222 , A61K31/223 , A61K31/401 , A61K31/4015 , A61K31/4365 , A61K31/519 , A61K31/616 , A61K38/00 , A61K45/06 , C07K5/0205 , C07K5/06026 , C07K5/0606 , C07K5/06069 , C07K5/06078 , C07K5/06165 , A61K2300/00 , A23V2200/326 , A23V2250/06
摘要： This invention relates to pharmaceutical compounds and nutritional supplements that are acetylated derivatives of naturally occurring amino acids and acetylated derivatives of peptides derived from naturally occurring amino acids containing hydroxyl groups. They are as useful as anti-platelet drugs, and as nutritional supplements.
摘要翻译： 本发明涉及天然氨基酸的乙酰化衍生物和衍生自含有羟基的天然存在的氨基酸的肽的乙酰化衍生物的药物化合物和营养补充剂。 它们与抗血小板药物和营养补充剂一样有用。
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2.发明授权Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements 有权乙酰氨基酸作为抗血小板剂，营养和维生素补充剂公开(公告)号：US08003683B2
公开(公告)日：2011-08-23
申请号：US11598425
申请日：2006-11-13
申请人： V. Ravi Chandran
发明人： V. Ravi Chandran
IPC分类号： A61K31/4015 , A61K31/22
CPC分类号： A61K31/40 , A23L2/52 , A23L33/175 , A23V2002/00 , A61K31/198 , A61K31/22 , A61K31/221 , A61K31/222 , A61K31/223 , A61K31/401 , A61K31/4015 , A61K31/4365 , A61K31/519 , A61K31/616 , A61K38/00 , A61K45/06 , C07K5/0205 , C07K5/06026 , C07K5/0606 , C07K5/06069 , C07K5/06078 , C07K5/06165 , A61K2300/00 , A23V2200/326 , A23V2250/06
摘要： This invention relates to pharmaceutical compounds and nutritional supplements that are acetylated derivatives of naturally occurring amino acids and acetylated derivatives of peptides derived from naturally occurring amino acids containing hydroxyl groups. They are as useful as anti-platelet drugs, and as nutritional supplements.
摘要翻译： 本发明涉及天然氨基酸的乙酰化衍生物和衍生自含有羟基的天然存在的氨基酸的肽的乙酰化衍生物的药物化合物和营养补充剂。 它们与抗血小板药物和营养补充剂一样有用。
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3.发明授权Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements 有权乙酰氨基酸作为抗血小板剂，营养和维生素补充剂公开(公告)号：US08940791B2
公开(公告)日：2015-01-27
申请号：US13183013
申请日：2011-07-14
申请人： V. Ravi Chandran
发明人： V. Ravi Chandran
IPC分类号： A01N37/02 , A61K31/40 , A23L1/305 , A61K31/198 , A61K31/22 , A61K31/221 , A61K31/223 , A61K31/401 , A61K31/4015 , A61K31/4365 , A61K31/519 , A61K31/616 , A61K45/06 , C07K5/02 , C07K5/062 , C07K5/065 , C07K5/078 , A23L2/52 , A61K31/222 , A61K38/00
CPC分类号： A61K31/40 , A23L2/52 , A23L33/175 , A23V2002/00 , A61K31/198 , A61K31/22 , A61K31/221 , A61K31/222 , A61K31/223 , A61K31/401 , A61K31/4015 , A61K31/4365 , A61K31/519 , A61K31/616 , A61K38/00 , A61K45/06 , C07K5/0205 , C07K5/06026 , C07K5/0606 , C07K5/06069 , C07K5/06078 , C07K5/06165 , A61K2300/00 , A23V2200/326 , A23V2250/06
摘要： This invention relates to pharmaceutical compounds and nutritional supplements that are acetylated derivatives of naturally occurring amino acids and acetylated derivatives of peptides derived from naturally occurring amino acids containing hydroxyl groups. They are as useful as anti-platelet drugs, and as nutritional supplements.
摘要翻译： 本发明涉及天然氨基酸的乙酰化衍生物和衍生自含有羟基的天然存在的氨基酸的肽的乙酰化衍生物的药物化合物和营养补充剂。 它们与抗血小板药物和营养补充剂一样有用。
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4.发明申请ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS 审中-公开乙酰胺作为抗药剂，营养和维生素补充剂公开(公告)号：US20110312890A1
公开(公告)日：2011-12-22
申请号：US13195229
申请日：2011-08-01
申请人： V. Ravi Chandran
发明人： V. Ravi Chandran
IPC分类号： A61K38/05 , A61K31/401 , A61K31/616 , A61K31/4365 , A61K31/519 , C07K4/00 , C07C237/20 , C07C237/12 , C07D207/16 , C07D403/12 , A61K38/03 , C07C229/36 , C07C229/04 , A61P9/00 , A61P9/10 , A61P7/02 , A23L1/305 , A61K31/225
CPC分类号： A61K31/221 , A23L33/175 , A23V2002/00 , A61K31/223 , A61K31/401 , A61K31/4365 , A61K31/519 , A61K31/616 , A61K38/00 , A61K45/06 , C07K5/0205 , C07K5/06017 , C07K5/0606 , C07K5/06069 , C07K5/06078 , C07K5/06165 , A61K2300/00 , A23V2200/326
摘要： This invention relates to pharmaceutical compounds and nutritional supplements that are acetylated derivatives of naturally occurring amino acids and acetylated derivatives of peptides derived from naturally occurring amino acids containing hydroxyl groups. They are as useful as anti-platelet drugs, and as nutritional supplements.
摘要翻译： 本发明涉及天然氨基酸的乙酰化衍生物和衍生自含有羟基的天然存在的氨基酸的肽的乙酰化衍生物的药物化合物和营养补充剂。 它们与抗血小板药物和营养补充剂一样有用。
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公开(公告)号：US08563776B2
公开(公告)日：2013-10-22
申请号：US12556968
申请日：2009-09-10
申请人： V. Ravi Chandran
发明人： V. Ravi Chandran
IPC分类号： C07C229/00
CPC分类号： A61K38/12 , A61K38/10 , A61K45/06 , A61K47/542 , C07C229/08 , C07C229/22 , C07C229/26 , C07C229/36 , C07C233/47 , C07C2602/22 , C07D207/33 , C07D209/10 , C07D209/14 , C07D211/34 , C07D211/90 , C07D215/38 , C07D217/26 , C07D223/16 , C07D239/10 , C07D261/20 , C07D265/18 , C07D275/04 , C07D295/185 , C07D311/24 , C07D311/32 , C07D333/58 , C07D401/06 , C07D401/12 , C07D403/10 , C07D405/14 , C07D409/06 , C07D413/06 , C07D473/18 , C07D473/34 , C07D493/04 , C07D493/10 , C07D495/04 , C07D498/06 , C07D498/14 , C07D499/14 , C07D501/22 , C07D501/34 , C07D501/46 , C07D501/56 , C07F9/572 , C07F9/65616
摘要： The present invention is directed to a derivative comprised of an L-Threonine bonded to a medicament or drug having a hydroxy, amino, carboxy or acylating derivative thereon. The derivative has the same utility as the drug from which it is made, but it has enhanced therapeutic properties. In fact, the derivatives of the present invention enhance at least one or more therapeutic qualities, as defined herein. The present invention is also directed to pharmaceutical compositions containing same.
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公开(公告)号：US20120289471A1
公开(公告)日：2012-11-15
申请号：US13449791
申请日：2012-04-18
申请人： V. Ravi Chandran
发明人： V. Ravi Chandran
IPC分类号： C07K7/64 , A61K31/702 , A61K38/13 , C07D499/68 , A61K31/43 , C07H17/08 , A61K31/7048 , C07C229/36 , A61K31/223 , C07D207/16 , A61K31/401 , C07C69/612 , A61K31/24 , C07C69/757 , A61K31/215 , A61K31/616 , C07D491/16 , A61K31/436 , C07D495/04 , A61K31/4365 , C07J71/00 , A61K31/58 , A61P29/00 , A61P37/06 , C07H15/203
CPC分类号： A61K38/12 , A61K47/542 , C07C229/08 , C07C229/22 , C07C229/26 , C07C229/36 , C07C233/47 , C07C2602/22 , C07D207/33 , C07D209/10 , C07D209/14 , C07D211/34 , C07D211/90 , C07D215/38 , C07D217/26 , C07D223/16 , C07D239/10 , C07D261/20 , C07D265/18 , C07D275/04 , C07D295/185 , C07D311/24 , C07D311/32 , C07D333/58 , C07D401/06 , C07D401/12 , C07D403/10 , C07D405/14 , C07D409/06 , C07D413/06 , C07D473/18 , C07D473/34 , C07D493/04 , C07D493/10 , C07D495/04 , C07D498/06 , C07D498/14 , C07D499/14 , C07D501/22 , C07D501/34 , C07D501/46 , C07D501/56 , C07F9/572 , C07F9/65616 , Y02A50/411
摘要： The present invention is directed to novel therapeutic compounds comprised of an amino acid bonded to a medicament or drug having a hydroxy, amino, carboxy or acylating derivative thereon. These high therapeutic index derivatives have the same utility as the drug from which they are made, and they have enhanced pharmacological and pharmaceutical properties. In fact, the novel drug derivatives of the present invention enhance at least one therapeutic quality, as defined herein. The present invention is also directed to pharmaceutical compositions containing same.
摘要翻译： 本发明涉及由与其上具有羟基，氨基，羧基或酰化衍生物的药物或药物结合的氨基酸组成的新型治疗化合物。 这些高治疗指数衍生物与其制备的药物具有相同的效用，并且它们具有增强的药理学和药物性质。 事实上，本发明的新型药物衍生物增强至少一种如本文所定义的治疗质量。 本发明还涉及含有其的药物组合物。
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公开(公告)号：US20100069489A1
公开(公告)日：2010-03-18
申请号：US12557080
申请日：2009-09-10
申请人： V. Ravi Chandran
发明人： V. Ravi Chandran
IPC分类号： A61K31/216 , A61P29/00
CPC分类号： A61K38/12 , A61K38/10 , A61K45/06 , A61K47/542 , C07C229/08 , C07C229/22 , C07C229/26 , C07C229/36 , C07C233/47 , C07C2602/22 , C07D207/33 , C07D209/10 , C07D209/14 , C07D211/34 , C07D211/90 , C07D215/38 , C07D217/26 , C07D223/16 , C07D239/10 , C07D261/20 , C07D265/18 , C07D275/04 , C07D295/185 , C07D311/24 , C07D311/32 , C07D333/58 , C07D401/06 , C07D401/12 , C07D403/10 , C07D405/14 , C07D409/06 , C07D413/06 , C07D473/18 , C07D473/34 , C07D493/04 , C07D493/10 , C07D495/04 , C07D498/06 , C07D498/14 , C07D499/14 , C07D501/22 , C07D501/34 , C07D501/46 , C07D501/56 , C07F9/572 , C07F9/65616
摘要： The present invention is directed to a derivative comprised of an L-Threonine bonded to a medicament or drug having a hydroxy, amino, carboxy or acylating derivative thereon. The derivative has the same utility as the drug from which it is made, but it has enhanced therapeutic properties. In fact, the derivatives of the present invention enhance at least one or more therapeutic qualities, as defined herein. The present invention is also directed to pharmaceutical compositions containing same.
摘要翻译： 本发明涉及由与其上具有羟基，氨基，羧基或酰化衍生物的药物或药物结合的L-苏氨酸组成的衍生物。 该衍生物与其制备的药物具有相同的效用，但具有增强的治疗性质。 事实上，本发明的衍生物增强至少一种或多种如本文所定义的治疗质量。 本发明还涉及含有其的药物组合物。
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公开(公告)号：US08188311B2
公开(公告)日：2012-05-29
申请号：US12557030
申请日：2009-09-10
申请人： V. Ravi Chandran
发明人： V. Ravi Chandran
IPC分类号： C07C229/00
CPC分类号： A61K38/12 , A61K38/10 , A61K45/06 , A61K47/542 , C07C229/08 , C07C229/22 , C07C229/26 , C07C229/36 , C07C233/47 , C07C2602/22 , C07D207/33 , C07D209/10 , C07D209/14 , C07D211/34 , C07D211/90 , C07D215/38 , C07D217/26 , C07D223/16 , C07D239/10 , C07D261/20 , C07D265/18 , C07D275/04 , C07D295/185 , C07D311/24 , C07D311/32 , C07D333/58 , C07D401/06 , C07D401/12 , C07D403/10 , C07D405/14 , C07D409/06 , C07D413/06 , C07D473/18 , C07D473/34 , C07D493/04 , C07D493/10 , C07D495/04 , C07D498/06 , C07D498/14 , C07D499/14 , C07D501/22 , C07D501/34 , C07D501/46 , C07D501/56 , C07F9/572 , C07F9/65616
摘要： The present invention is directed to a derivative comprised of an L-Threonine bonded to a medicament or drug having a hydroxy, amino, carboxy or acylating derivative thereon. The derivative has the same utility as the drug from which it is made, but it has enhanced therapeutic properties. In fact, the derivatives of the present invention enhance at least one or more therapeutic qualities, as defined herein. The present invention is also directed to pharmaceutical compositions containing same.
摘要翻译： 本发明涉及由与其上具有羟基，氨基，羧基或酰化衍生物的药物或药物结合的L-苏氨酸组成的衍生物。 该衍生物与其制备的药物具有相同的效用，但具有增强的治疗性质。 事实上，本发明的衍生物增强至少一种或多种如本文所定义的治疗质量。 本发明还涉及含有其的药物组合物。
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公开(公告)号：US20100004481A1
公开(公告)日：2010-01-07
申请号：US12556968
申请日：2009-09-10
申请人： V. Ravi Chandran
发明人： V. Ravi Chandran
IPC分类号： C07C69/88 , C07C229/00
CPC分类号： A61K38/12 , A61K38/10 , A61K45/06 , A61K47/542 , C07C229/08 , C07C229/22 , C07C229/26 , C07C229/36 , C07C233/47 , C07C2602/22 , C07D207/33 , C07D209/10 , C07D209/14 , C07D211/34 , C07D211/90 , C07D215/38 , C07D217/26 , C07D223/16 , C07D239/10 , C07D261/20 , C07D265/18 , C07D275/04 , C07D295/185 , C07D311/24 , C07D311/32 , C07D333/58 , C07D401/06 , C07D401/12 , C07D403/10 , C07D405/14 , C07D409/06 , C07D413/06 , C07D473/18 , C07D473/34 , C07D493/04 , C07D493/10 , C07D495/04 , C07D498/06 , C07D498/14 , C07D499/14 , C07D501/22 , C07D501/34 , C07D501/46 , C07D501/56 , C07F9/572 , C07F9/65616
摘要： The present invention is directed to a derivative comprised of an L-Threonine bonded to a medicament or drug having a hydroxy, amino, carboxy or acylating derivative thereon. The derivative has the same utility as the drug from which it is made, but it has enhanced therapeutic properties. In fact, the derivatives of the present invention enhance at least one or more therapeutic qualities, as defined herein. The present invention is also directed to pharmaceutical compositions containing same.
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公开(公告)号：US07589233B2
公开(公告)日：2009-09-15
申请号：US11442027
申请日：2006-05-26
申请人： V. Ravi Chandran
发明人： V. Ravi Chandran
IPC分类号： C07C229/00
CPC分类号： A61K38/12 , A61K38/10 , A61K45/06 , A61K47/542 , C07C229/08 , C07C229/22 , C07C229/26 , C07C229/36 , C07C233/47 , C07C2602/22 , C07D207/33 , C07D209/10 , C07D209/14 , C07D211/34 , C07D211/90 , C07D215/38 , C07D217/26 , C07D223/16 , C07D239/10 , C07D261/20 , C07D265/18 , C07D275/04 , C07D295/185 , C07D311/24 , C07D311/32 , C07D333/58 , C07D401/06 , C07D401/12 , C07D403/10 , C07D405/14 , C07D409/06 , C07D413/06 , C07D473/18 , C07D473/34 , C07D493/04 , C07D493/10 , C07D495/04 , C07D498/06 , C07D498/14 , C07D499/14 , C07D501/22 , C07D501/34 , C07D501/46 , C07D501/56 , C07F9/572 , C07F9/65616
摘要： The present invention is directed to a derivative comprised of an L-Threonine bonded to a medicament or drug having a hydroxy, amino, carboxy or acylating derivative thereon. The derivative has the same utility as the drug from which it is made, but it has enhanced therapeutic properties. In fact, the derivatives of the present invention enhance at least one or more therapeutic qualities, as defined herein. The present invention is also directed to pharmaceutical compositions containing same.
摘要翻译： 本发明涉及由与其上具有羟基，氨基，羧基或酰化衍生物的药物或药物结合的L-苏氨酸组成的衍生物。 该衍生物与其制备的药物具有相同的效用，但具有增强的治疗性质。 事实上，本发明的衍生物增强至少一种或多种如本文所定义的治疗质量。 本发明还涉及含有其的药物组合物。
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