公开(公告)号：US20150376248A1

公开(公告)日：2015-12-31

申请号：US14765016

申请日：2014-01-31

Applicant: VIRGINIA COMMONWEALTH UNIVERSITY

Inventor： Nicholas E. Kurland ,  Vamsi K. Yadavalli

IPC: C07K14/435 ,  G03F7/20 ,  G03F7/26 ,  C07K1/107

CPC classification number: C07K14/43586 ,  C07K1/1072 ,  C07K1/1077 ,  G03F7/038 ,  G03F7/0388 ,  G03F7/20 ,  G03F7/26

Abstract: A natural protein, specifically silk fibroin or sericin, is chemically modified such that it can be rendered photoactive, but which otherwise has similar structure and attributes as silk fibroin or sericin. This chemically modified silk conjugate can be patterned using radiant energy to produce patterned silk materials which may be used for a wide variety of applications such as making micro and nanoparticles of different shapes and functionalities for drug delivery, creating new forms of intricate 3D scaffolds for tissue engineering, and forming substrates for flexible bio-electronics.

Abstract translation: 化学修饰天然蛋白质，特别是丝素蛋白或丝胶蛋白，使其能够呈现光活性，但其具有与丝素蛋白或丝胶蛋白相似的结构和属性。 这种化学改性的丝绸缀合物可以使用辐射能图案化以产生图案化丝材料，其可用于各种应用，例如制备用于药物递送的不同形状和功能的微型和纳米颗粒，为组织创造复杂的3D支架的新形式 工程和形成柔性生物电子基材。

公开(公告)号：US09771400B2

公开(公告)日：2017-09-26

申请号：US14765016

申请日：2014-01-31

Applicant: VIRGINIA COMMONWEALTH UNIVERSITY

Inventor： Nicholas E. Kurland ,  Vamsi K. Yadavalli

IPC: G03F7/038 ,  C07K14/435 ,  C07K1/107 ,  G03F7/20 ,  G03F7/26

CPC classification number: C07K14/43586 ,  C07K1/1072 ,  C07K1/1077 ,  G03F7/038 ,  G03F7/0388 ,  G03F7/20 ,  G03F7/26

Abstract: A natural protein, specifically silk fibroin or sericin, is chemically modified such that it can be rendered photoactive, but which otherwise has similar structure and attributes as silk fibroin or sericin. This chemically modified silk conjugate can be patterned using radiant energy to produce patterned silk materials which may be used for a wide variety of applications such as making micro and nanoparticles of different shapes and functionalities for drug delivery, creating new forms of intricate 3D scaffolds for tissue engineering, and forming substrates for flexible bio-electronics.

公开(公告)号：US10655024B2

公开(公告)日：2020-05-19

申请号：US16000948

申请日：2018-06-06

Applicant: Virginia Commonwealth University

Inventor： Vamsi K. Yadavalli ,  Ramendra K. Pal

IPC: C09D11/04 ,  C09D11/52 ,  C09D11/037 ,  C09D11/102 ,  G03F7/039 ,  G03F7/038 ,  H01G11/78 ,  G03F7/16 ,  G03F7/32 ,  H01G11/48 ,  H01G11/56 ,  H01G11/36 ,  H01G11/86 ,  G03F7/20 ,  C09D11/106 ,  H01G11/26

Abstract: Provided herein is biodegradable supercapacitor system comprising a protein based flexible thin film substrate, patterned electrodes formed from a biocompatible conductive ink, and biocompatible gel electrolyte. Methods of making the supercapacitor system are also provided.

公开(公告)号：US20180355194A1

公开(公告)日：2018-12-13

申请号：US16000948

申请日：2018-06-06

Applicant: Virginia Commonwealth University

Inventor： Vamsi K. Yadavalli ,  Ramendra K. Pal

IPC: C09D11/04 ,  C09D11/52 ,  C09D11/037 ,  C09D11/102 ,  G03F7/039 ,  G03F7/038 ,  G03F7/20 ,  G03F7/16 ,  G03F7/32 ,  H01G11/48 ,  H01G11/56 ,  H01G11/36 ,  H01G11/86 ,  H01G11/78

CPC classification number: C09D11/04 ,  C09D11/037 ,  C09D11/102 ,  C09D11/52 ,  G03F7/038 ,  G03F7/039 ,  G03F7/16 ,  G03F7/2002 ,  G03F7/32 ,  H01G11/36 ,  H01G11/48 ,  H01G11/56 ,  H01G11/78 ,  H01G11/86

Abstract: Provided herein is biodegradable supercapacitor system comprising a protein based flexible thin film substrate, patterned electrodes formed from a biocompatible conductive ink, and biocompatible gel electrolyte. Methods of making the supercapacitor system are also provided.