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    NMR, MRI, and Spectroscopic MRI in Inhomogeneous Fields
    9.
    发明申请
    NMR, MRI, and Spectroscopic MRI in Inhomogeneous Fields 有权
    核磁共振，MRI和光谱MRI在不均匀场

    公开(公告)号：US20100102811A1

    公开(公告)日：2010-04-29

    申请号：US11917639

    申请日：2006-06-16

    申请人： Vasiliki Demas ,  Alexander Pines ,  Rachel W. Martin ,  John Franck ,  Jeffrey A. Reimer

    发明人： Vasiliki Demas ,  Alexander Pines ,  Rachel W. Martin ,  John Franck ,  Jeffrey A. Reimer

    IPC分类号： G01R33/48 ,  G01R23/00

    CPC分类号： G01R33/4833 ,  G01N24/084 ,  G01R33/3808 ,  G01R33/445 ,  G01R33/485 ,  G01R33/56563

    摘要： A method for locally creating effectively homogeneous or “clean” magnetic field gradients (of high uniformity) for imaging (with NMR, MRI, or spectroscopic MRI) both in in-situ and ex-situ systems with high degrees of inhomogeneous field strength. The method of imaging comprises: a) providing a functional approximation of an inhomogeneous static magnetic field strength B0 (r) at a spatial position r; b) providing a temporal functional approximation of Gshim(t) with i basis functions and j variables for each basis function, resulting in vij variables; c) providing a measured value Ω, which is an temporally accumulated dephasing due to the inhomogeneities of B0 (r); and d) minimizing a difference in the local dephasing angle (I) by varying the vij variables to form a set of minimized vij variables. The method requires calibration of the static fields prior to minimization, but may thereafter he implemented without such calibration, may he used in open or closed systems, and potentially portable systems.

    摘要翻译： 在具有高度不均匀场强的原位和非原位系统中，用于局部创建有效均匀或“清洁”磁场梯度（高均匀度））用于成像（使用NMR，MRI或光谱MRI）的方法。 成像方法包括：a）在空间位置r处提供非均匀静态磁场强度B0（r）的函数近似值; b）提供Gshim（t）的时间函数近似与i基函数和每个基函数的j变量，导致vij变量; c）提供由于B0（r）的不均匀性而导致的时间累积去相位的测量值＆amp; 以及d）通过改变vij变量来最小化局部相移角（I）的差异以形成一组最小化的vij变量。 该方法需要在最小化之前对静态场进行校准，然后可以在不进行这种校准的情况下进行实施，可以在开放或封闭的系统以及潜在的便携式系统中使用。