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公开(公告)号：US08540764B2
公开(公告)日：2013-09-24
申请号：US12425616
申请日：2009-04-17
申请人： Walter Bruszewski , Peggy Grills , Frank Harewood , Lana Woolley
发明人： Walter Bruszewski , Peggy Grills , Frank Harewood , Lana Woolley
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2/954 , A61F2002/061 , A61F2002/075 , A61F2002/30065 , A61F2002/30074 , A61F2002/30092 , A61F2002/30125 , A61F2002/30327 , A61F2002/30604 , A61F2002/821 , A61F2002/9665 , A61F2210/0014 , A61F2210/0057 , A61F2210/0071 , A61F2230/0008 , A61F2250/0039 , A61F2250/006
摘要： An endovascular prosthesis includes a tubular body and a mobile external coupling. The tubular body includes a graft material and stents coupled thereto, a forms a lumen therethrough. The mobile external coupling extends outwardly from the tubular body. The mobile external coupling includes a graft material and is generally frustoconically shaped. The mobile external coupling includes a base coupled to the tubular body, a top spaced from the tubular body, and a coupling lumen disposed between the base and the top, wherein the coupling lumen is in flow communication with the body lumen. The coupling graft material is a woven fabric with warp yarn which run generally parallel to a longitudinal axis of the mobile external coupling including a shape memory material.
摘要翻译： 血管内假体包括管状主体和移动外部联接器。 管状体包括移植材料和与其连接的支架，a形成通过其中的腔。 移动外部联接件从管状体向外延伸。 移动外部联接件包括移植材料并且通常是截头圆锥形的。 移动外部联接器包括联接到管状体的基部，与管状体间隔开的顶部以及设置在基部和顶部之间的联接腔，其中联接腔与体腔流动连通。 联接移植材料是具有大致平行于包括形状记忆材料的移动外部联接器的纵向轴线延伸的经纱的机织织物。
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公开(公告)号：US20100268327A1
公开(公告)日：2010-10-21
申请号：US12425616
申请日：2009-04-17
申请人： Walter Bruszewski , Peggy Grills , Frank Harewood , Lana Woolley
发明人： Walter Bruszewski , Peggy Grills , Frank Harewood , Lana Woolley
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2/954 , A61F2002/061 , A61F2002/075 , A61F2002/30065 , A61F2002/30074 , A61F2002/30092 , A61F2002/30125 , A61F2002/30327 , A61F2002/30604 , A61F2002/821 , A61F2002/9665 , A61F2210/0014 , A61F2210/0057 , A61F2210/0071 , A61F2230/0008 , A61F2250/0039 , A61F2250/006
摘要： An endovascular prosthesis includes a tubular body and a mobile external coupling. The tubular body includes a graft material and stents coupled thereto, a forms a lumen therethrough. The mobile external coupling extends outwardly from the tubular body. The mobile external coupling includes a graft material and is generally frustoconically shaped. The mobile external coupling includes a base coupled to the tubular body, a top spaced from the tubular body, and a coupling lumen disposed between the base and the top, wherein the coupling lumen is in flow communication with the body lumen. The coupling graft material is a woven fabric with warp yarn which run generally parallel to a longitudinal axis of the mobile external coupling including a shape memory material.
摘要翻译： 血管内假体包括管状主体和移动外部联接器。 管状体包括移植材料和与其连接的支架，a形成通过其中的腔。 移动外部联接件从管状体向外延伸。 移动外部联接件包括移植材料并且通常是截头圆锥形的。 移动外部联接器包括联接到管状体的基部，与管状体间隔开的顶部以及设置在基部和顶部之间的联接腔，其中联接腔与体腔流动连通。 联接移植材料是具有大致平行于包括形状记忆材料的移动外部联接器的纵向轴线延伸的经纱的机织织物。
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公开(公告)号：US20120136417A1
公开(公告)日：2012-05-31
申请号：US13279327
申请日：2011-10-23
申请人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Seamus Ledwith , Gwenda McMullin , Karun D. Naga , Stephen Nash , Francesco Piccagli , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Seamus Ledwith , Gwenda McMullin , Karun D. Naga , Stephen Nash , Francesco Piccagli , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
IPC分类号： A61F7/12
CPC分类号： A61B18/02 , A61B2017/22054 , A61B2017/22067 , A61B2018/00023 , A61B2018/00166 , A61B2018/0022 , A61B2018/00232 , A61B2018/0025 , A61B2018/00261 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
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公开(公告)号：US20120136344A1
公开(公告)日：2012-05-31
申请号：US13279321
申请日：2011-10-23
申请人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/22054 , A61B2017/22067 , A61B2018/00023 , A61B2018/00166 , A61B2018/0022 , A61B2018/00232 , A61B2018/0025 , A61B2018/00261 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
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5.发明申请公开(公告)号：US20120136418A1
公开(公告)日：2012-05-31
申请号：US13279328
申请日：2011-10-23
申请人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Seamus Ledwith , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Seamus Ledwith , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
IPC分类号： A61F7/12
CPC分类号： A61B18/02 , A61B2018/00214 , A61B2018/00232 , A61B2018/00255 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/0212
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
摘要翻译： 本文公开了神经调节冷冻治疗装置及相关系统和方法。 根据本技术的特定实施例配置的冷冻治疗装置可以包括细长轴，其具有沿轴的至少一部分的远侧部分和供应内腔。 轴可以被配置为将远端部分血管内定位在肾动脉或肾口附近的治疗部位。 供应内腔可被配置为接收液体制冷剂。 冷冻治疗装置还可以包括在轴的远端处的冷却组件。 冷却组件可以包括与供应内腔流体连通的施加器，并且构造成当冷却组件处于展开状态时，将冷冻治疗冷却递送到靠近目标部位的神经。
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公开(公告)号：US09439708B2
公开(公告)日：2016-09-13
申请号：US13279326
申请日：2011-10-23
申请人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins , Michael Turovskiy
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins , Michael Turovskiy
CPC分类号： A61B18/02 , A61B2017/22054 , A61B2017/22067 , A61B2018/00023 , A61B2018/00166 , A61B2018/0022 , A61B2018/00232 , A61B2018/0025 , A61B2018/00261 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
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7.发明授权公开(公告)号：US09060754B2
公开(公告)日：2015-06-23
申请号：US13279328
申请日：2011-10-23
申请人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Seamus Ledwith , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Seamus Ledwith , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
CPC分类号： A61B18/02 , A61B2018/00214 , A61B2018/00232 , A61B2018/00255 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/0212
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment includes an elongated shaft and a cooling assembly at a distal portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site within or otherwise proximate a renal artery. The cryotherapeutic device can further include a supply lumen configured to carry liquid refrigerant toward the cooling assembly. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when in a deployed state.
摘要翻译： 本文公开了神经调节冷冻治疗装置及相关系统和方法。 根据特定实施例构造的冷冻治疗装置包括细长轴和在轴的远端部分处的冷却组件。 轴可以被配置为将血管内远端部分定位在肾动脉内或其他邻近肾动脉处的处置部位。 冷冻治疗装置还可以包括被配置为将液体制冷剂运送到冷却组件的供应管腔。 冷却组件可以包括与供应内腔流体连通的施加器，并且构造成当处于展开状态时，将冷冻治疗冷却递送到靠近目标部位的神经。
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公开(公告)号：US20120130360A1
公开(公告)日：2012-05-24
申请号：US13279326
申请日：2011-10-23
申请人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins , Michael Turovskiy
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins , Michael Turovskiy
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/22054 , A61B2017/22067 , A61B2018/00023 , A61B2018/00166 , A61B2018/0022 , A61B2018/00232 , A61B2018/0025 , A61B2018/00261 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
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9.发明授权公开(公告)号：US09060755B2
公开(公告)日：2015-06-23
申请号：US13279330
申请日：2011-10-23
申请人： Naomi Buckley , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Micheal Moriarty , Karun D. Naga , Fiachra Sweeney , Vincenzo Tilotta , Ronan Wood , Lana Woolley , Denise Zarins , Mark S. Leung , Mark Gelfand , Barry Mullins
发明人： Naomi Buckley , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Micheal Moriarty , Karun D. Naga , Fiachra Sweeney , Vincenzo Tilotta , Ronan Wood , Lana Woolley , Denise Zarins , Mark S. Leung , Mark Gelfand , Barry Mullins
CPC分类号： A61B18/02 , A61B2017/22054 , A61B2017/22067 , A61B2018/00023 , A61B2018/00166 , A61B2018/0022 , A61B2018/00232 , A61B2018/0025 , A61B2018/00261 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
摘要翻译： 本文公开了神经调节冷冻治疗装置及相关系统和方法。 根据本技术的特定实施例配置的冷冻治疗装置可以包括细长轴，其具有沿轴的至少一部分的远侧部分和供应内腔。 轴可以被配置为将远端部分血管内定位在肾动脉或肾口附近的治疗部位。 供应内腔可被配置为接收液体制冷剂。 冷冻治疗装置还可以包括在轴的远端处的冷却组件。 冷却组件可以包括与供应内腔流体连通的施加器，并且构造成当冷却组件处于展开状态时，将冷冻治疗冷却递送到靠近目标部位的神经。
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公开(公告)号：US08945107B2
公开(公告)日：2015-02-03
申请号：US13279327
申请日：2011-10-23
申请人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Seamus Ledwith , Gwenda McMullin , Karun D. Naga , Stephen Nash , Francesco Piccagli , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Seamus Ledwith , Gwenda McMullin , Karun D. Naga , Stephen Nash , Francesco Piccagli , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
CPC分类号： A61B18/02 , A61B2017/22054 , A61B2017/22067 , A61B2018/00023 , A61B2018/00166 , A61B2018/0022 , A61B2018/00232 , A61B2018/0025 , A61B2018/00261 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
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