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公开(公告)号:US09687156B2
公开(公告)日:2017-06-27
申请号:US14342442
申请日:2012-09-07
申请人: Waltherus Cornelis Jozef Bierhoff , Bernardus Hendrikus Wilhelmus Hendriks , Franciscus Marinus Antonius Maria Van Gaal
发明人: Waltherus Cornelis Jozef Bierhoff , Bernardus Hendrikus Wilhelmus Hendriks , Franciscus Marinus Antonius Maria Van Gaal
CPC分类号: A61B5/0084 , A61B5/0071 , A61B5/0075 , A61B5/0086 , A61B5/6844 , A61B5/6848
摘要: A needle device includes a hollow shaft, an elongated insert and an operating lever. The hollow shaft has a first distal end portion with a bevel, the elongated insert has a second distal end portion and is movably arranged within the hollow shaft, and the operating lever is shiftable between a first condition and a second condition. Furthermore, the operating lever is interconnected with the elongated insert such that the second distal end portion is located within the hollow shaft and proximally to the bevel when the operating lever is in the first condition, and that the second distal end portion is located outside the hollow shaft and distally to the bevel when the operating lever is in the second condition.
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公开(公告)号:US20140213911A1
公开(公告)日:2014-07-31
申请号:US14342442
申请日:2012-09-07
申请人: Waltherus Cornelis Jozef Bierhoff , Bernardus Hendrikus Wilhelmus Hendriks , Franciscus Marinus Antonius Maria Van Gaal
发明人: Waltherus Cornelis Jozef Bierhoff , Bernardus Hendrikus Wilhelmus Hendriks , Franciscus Marinus Antonius Maria Van Gaal
IPC分类号: A61B5/00
CPC分类号: A61B5/0084 , A61B5/0071 , A61B5/0075 , A61B5/0086 , A61B5/6844 , A61B5/6848
摘要: A needle device according to the invention comprises a hollow shaft, an elongated insert and an operating means. The hollow shaft has a first distal end portion with a bevel, the elongated insert has a second distal end portion and is movably arranged within the hollow shaft, and the operating means is shiftable between a first condition and a second condition. Furthermore, the operating means is interconnected with the elongated insert, so that the second distal end portion is located within the hollow shaft and proximally to the bevel, when the operating means is in the first condition, and that the second distal end portion is located outside the hollow shaft and distally to the bevel, when the operating means is in the second condition.
摘要翻译: 根据本发明的针装置包括中空轴,细长插入件和操作装置。 空心轴具有带斜面的第一远端部分,细长插入件具有第二远端部分,并且可移动地布置在中空轴内,并且操作装置可在第一状态和第二状态之间移动。 此外,操作装置与细长插入件互连,使得当操作装置处于第一状态时,第二远端部分位于空心轴内并且向近侧位于斜面,并且第二远端部分位于 当操作装置处于第二状态时,在空心轴之外并且远离斜面。
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公开(公告)号:US20110218445A1
公开(公告)日:2011-09-08
申请号:US13129206
申请日:2009-06-15
申请人: Augustinus Laurentius Braun , Bernardus Hendrikus Wilhelmus Hendriks , Rik Harbers , Marjolein Van Der Voort , Adrien Emmanuel Desjardins , Rami Nachabe , Bernardus Wilhelmus Johannes Wassink , Franciscus Marinus Antonius Maria Van Gaal , Nenad Mihajlovic , Drazenko Babic
发明人: Augustinus Laurentius Braun , Bernardus Hendrikus Wilhelmus Hendriks , Rik Harbers , Marjolein Van Der Voort , Adrien Emmanuel Desjardins , Rami Nachabe , Bernardus Wilhelmus Johannes Wassink , Franciscus Marinus Antonius Maria Van Gaal , Nenad Mihajlovic , Drazenko Babic
CPC分类号: A61B5/6848 , A61B5/0075 , A61B5/0084
摘要: Needles equipped with fibres allow tissue inspection based on optical spectroscopy to diagnose whether tissue is cancerous or not. This requires integration of optical fibers into needles. The problem is how to manufacture the needle having at least one fiber exit at the distal end of the needle, where the fiber does not obstruct the hollow part of the needle if present as well as does not extend beyond the outer cylinder geometry. To solve this problem we propose to manufacture the needle consisting of four parts: an inner cylinder tube, an outer hollow cylinder tube, a needle tip part with integrated fiber exit and a holder part, wherein the hollow spacing between the inner and the outer cylinder is larger or equal to the outer diameter of the fibers, the inner and the outer cylinder are mounted in the holder part and where the tip part is mounted on the two cylinders.
摘要翻译: 配备纤维的针头允许基于光谱的组织检查来诊断组织是否是癌变的。 这需要将光纤集成到针中。 问题是如何制造在针的远端具有至少一个纤维出口的针,其中纤维不会阻塞针的中空部分,如果存在,并且不延伸超出外筒几何形状。 为了解决这个问题,我们建议制造由四部分组成的针:内筒管,外空心筒管,具有集成纤维出口的针尖部分和保持器部分,其中内筒和外筒之间的中空间隔 大于或等于纤维的外径,内筒和外筒安装在保持器部分中,并且尖端部分安装在两个气缸上。
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公开(公告)号:US20120113491A1
公开(公告)日:2012-05-10
申请号:US13320601
申请日:2010-05-10
申请人: Cornelius Antonius Hezemans , Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Augustinus Laurentius Braun , Nenad Mihajlovic
发明人: Cornelius Antonius Hezemans , Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Augustinus Laurentius Braun , Nenad Mihajlovic
IPC分类号: G02B26/10
CPC分类号: A61B5/6848 , A61B5/0068 , A61B5/0084 , G02B21/0012 , G02B21/0036 , G02B23/2423 , G02B23/26 , G02B26/103
摘要: The present invention relates to an optical probe (1) suitable for miniature applications. An example application is a fibre-based confocal miniaturized microscope. The optical probe comprises a coil-based actuation system (9, 10) comprising drive coils (9) capable of displacing the distal end (3) of an optical guide (2) housed (4) by the optical probe. The probe makes use of a feedback loop which alternate between driving the displacement of the optical guide by driving a current through the drive coils and switching off the current through the drive coils, and while the drive current being switched off, measure the speed of the distal end of the optical guide. The measured speed is compared to the set-point speed, and if a difference is detected, the drive current is adjusted to eliminate, or at least bring down, this difference.
摘要翻译: 本发明涉及适合于微型应用的光学探头(1)。 一个示例应用是基于光纤的共聚焦微型显微镜。 光探头包括基于线圈的致动系统(9,10),其包括驱动线圈(9),该驱动线圈能够移动由光学探头容纳(4)的光导(2)的远端(3)。 探头利用反馈回路,通过驱动通过驱动线圈的电流驱动光导的位移和切断通过驱动线圈的电流之间的交替,并且在驱动电流被切断时,测量速度 光导的远端。 将测量的速度与设定点速度进行比较,并且如果检测到差异,则调节驱动电流以消除或至少降低该差异。
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公开(公告)号:US20110201941A1
公开(公告)日:2011-08-18
申请号:US13125392
申请日:2009-10-19
申请人: Franciscus Martinus Antonius Maria Van Gaal , Bernardus Hendrikus Wilhelmus Hendriks , Augustinus Laurentius Braun , Cornelius Antonius Hezemans , Waltherus Cornelis Jozef Bierhoff
发明人: Franciscus Martinus Antonius Maria Van Gaal , Bernardus Hendrikus Wilhelmus Hendriks , Augustinus Laurentius Braun , Cornelius Antonius Hezemans , Waltherus Cornelis Jozef Bierhoff
IPC分类号: A61B6/00
CPC分类号: A61B5/0062 , A61B5/0084 , G02B23/2461 , G02B26/103
摘要: The present invention relates to an optical scanning probe assembly for microscopic guide optic scanning and inspection of tissues suitable for application in, e.g. in vivo medical inspection and biopsy. The assembly comprises an outer housing (3) comprising: i) a spring element for a scanning motor, the spring element formed as a hollow tube (5) adapted to receive an optical guide, the hollow tube having mechanical stiffness larger than the optical guide to be received, ii) a lens system (7) and iii) N means for deflecting (6) the distal end of the hollow tube in directions transverse to the longitudinal extension of the hollow tube, so as to form an optical scan pattern. The optical assembly is particularly advantageous as it increases the freedom to optimize the optical and mechanical performance of the system which is defined respectively by the optical guide and by the hollow tube. The probe can be used in resonant and non-resonant scanning modes.
摘要翻译: 本发明涉及一种光学扫描探针组件,用于微观引导光学扫描和检查适用于例如, 体内检查和活检。 该组件包括外壳(3),包括:i)用于扫描电机的弹簧元件,弹簧元件形成为适于容纳光导的中空管(5),所述中空管的机械刚度大于光导 ii)透镜系统(7),以及iii)用于使中空管的远端沿垂直于中空管的纵向延伸的方向偏转(6)的装置,以形成光学扫描图案。 光学组件是特别有利的,因为它增加了由光导和中空管分别限定的优化系统的光学和机械性能的自由度。 探头可用于谐振和非谐振扫描模式。
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公开(公告)号:US09131846B2
公开(公告)日:2015-09-15
申请号:US13125392
申请日:2009-10-19
申请人: Franciscus Martinus Antonius Maria Van Gaal , Bernardus Hendrikus Wilhelmus Hendriks , Augustinus Laurentius Braun , Cornelius Antonius Hezemans , Waltherus Cornelis Jozef Bierhoff
发明人: Franciscus Martinus Antonius Maria Van Gaal , Bernardus Hendrikus Wilhelmus Hendriks , Augustinus Laurentius Braun , Cornelius Antonius Hezemans , Waltherus Cornelis Jozef Bierhoff
CPC分类号: A61B5/0062 , A61B5/0084 , G02B23/2461 , G02B26/103
摘要: An optical scanning probe assembly for microscopic guide optic scanning and inspection of tissues includes an outer housing having a spring element for a scanning motor. The spring element is formed as a hollow tube configured to receive an optical guide, where the hollow tube has a mechanical stiffness larger than the optical guide to be received. The assembly further includes a lens system and a deflector configured to deflect the distal end of the hollow tube in directions transverse to the longitudinal extension of the hollow tube, so as to form an optical scan pattern.
摘要翻译: 用于微小导向光学扫描和组织检查的光学扫描探针组件包括具有用于扫描电机的弹簧元件的外壳。 弹簧元件形成为构造成接收光导的中空管,其中中空管具有比要接收的光导更大的机械刚度。 组件还包括透镜系统和偏转器,其被配置为使中空管的远端沿垂直于中空管的纵向延伸的方向偏转,以形成光学扫描图案。
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公开(公告)号:US08717654B2
公开(公告)日:2014-05-06
申请号:US13320601
申请日:2010-05-10
申请人: Cornelius Antonius Hezemans , Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Augustinus Laurentius Braun , Nenad Mihajlovic
发明人: Cornelius Antonius Hezemans , Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Augustinus Laurentius Braun , Nenad Mihajlovic
CPC分类号: A61B5/6848 , A61B5/0068 , A61B5/0084 , G02B21/0012 , G02B21/0036 , G02B23/2423 , G02B23/26 , G02B26/103
摘要: The present invention relates to an optical probe (1) suitable for miniature applications. An example application is a fiber-based confocal miniaturized microscope. The optical probe comprises a coil-based actuation system (9, 10) comprising drive coils (9) capable of displacing the distal end (3) of an optical guide (2) housed (4) by the optical probe. The probe makes use of a feedback loop which alternate between driving the displacement of the optical guide by driving a current through the drive coils and switching off the current through the drive coils, and while the drive current being switched off, measure the speed of the distal end of the optical guide. The measured speed is compared to the set-point speed, and if a difference is detected, the drive current is adjusted to eliminate, or at least bring down, this difference.
摘要翻译: 本发明涉及适合于微型应用的光学探头(1)。 一个示例应用是基于光纤的共聚焦微型显微镜。 光探头包括基于线圈的致动系统(9,10),其包括驱动线圈(9),该驱动线圈能够移动由光学探头容纳(4)的光导(2)的远端(3)。 探头利用反馈回路,通过驱动通过驱动线圈的电流驱动光导的位移和切断通过驱动线圈的电流之间的交替,并且当驱动电流被切断时,测量速度 光导的远端。 将测量的速度与设定点速度进行比较,并且如果检测到差异,则调节驱动电流以消除或至少降低该差异。
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公开(公告)号:US20100207015A1
公开(公告)日:2010-08-19
申请号:US12668905
申请日:2008-07-14
申请人: Waltherus Cornelis Jozef Bierhoff , Bernardus Hendrikus Wilhelmus Hendriks , Augustinus Laurentius Braun , Nanad Mihajlovic
发明人: Waltherus Cornelis Jozef Bierhoff , Bernardus Hendrikus Wilhelmus Hendriks , Augustinus Laurentius Braun , Nanad Mihajlovic
IPC分类号: G02B26/10
CPC分类号: G02B26/101 , A61B5/0062 , A61B5/0084
摘要: A fiber scanning system is provided comprising a housing (102) with a fiber (13), the fiber (13) comprising a fixed part and a free end, the fixed part being attached to a bottom of the housing (102) and the fiber (13) extending parallel to the wall of the housing (102). At least one electrical coil (12) is attached to the wall at a position in between the fixed part and the free end of the fiber (13), a winding of the electrical coil (12) being in a plane parallel to the fiber (13). A magnet (11) is attached to the fiber (13), such that the electrical coil (12) may induce a force on the magnet (11). The magnet (11) is attached to the fiber (13) at a position just before or after the electrical coil (12), a width of the magnet (11) being such that the magnet (11) extends over the electrical coil (12).
摘要翻译: 提供一种纤维扫描系统,其包括具有纤维(13)的壳体(102),所述纤维(13)包括固定部分和自由端,所述固定部分附接到所述壳体(102)的底部,并且所述纤维 (13)平行于壳体(102)的壁延伸。 至少一个电线圈(12)在所述固定部分和所述光纤(13)的所述自由端之间的位置处附接到所述壁,所述电线圈(12)的绕组处于与所述光纤平行的平面( 13)。 磁体(11)附着在光纤(13)上,使得电线圈(12)可以在磁铁(11)上产生一个力。 磁体(11)在刚好在电线圈(12)之前或之后的位置处附接到光纤(13),磁体(11)的宽度使得磁体(11)在电线圈(12)上方延伸 )。
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公开(公告)号:US09072475B2
公开(公告)日:2015-07-07
申请号:US13881379
申请日:2011-10-17
申请人: Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Gerhardus Wilhelmus Lucassen , Rami Nachabe , Theodoor Jacques Marie Ruers
发明人: Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Gerhardus Wilhelmus Lucassen , Rami Nachabe , Theodoor Jacques Marie Ruers
IPC分类号: A61B5/1459 , A61B5/00 , A61M25/06
CPC分类号: A61B5/1459 , A61B5/0075 , A61B5/0084 , A61B5/6848 , A61B5/6882 , A61M25/065
摘要: A needle comprises an elongated first shaft element with a C-shaped cross section and an elongated second shaft element with a C-shaped cross section. The first shaft element and the second shaft element are adapted to be detachably connected to each other. This is achieved by an overlap of respective end sections of the first and second shaft elements. Within the channel formed by the shaft elements, an optical probe may be accommodated from which the shaft elements may be removed by separating the two shaft elements from each other.
摘要翻译: 针包括具有C形横截面的细长的第一轴元件和具有C形横截面的细长的第二轴元件。 第一轴元件和第二轴元件适于彼此可拆卸地连接。 这通过第一和第二轴元件的相应端部部分的重叠来实现。 在由轴元件形成的通道内,可以容纳光学探针,通过将两个轴元件彼此分离,可以从中移除轴元件。
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公开(公告)号:US20140142563A1
公开(公告)日:2014-05-22
申请号:US14131518
申请日:2012-07-05
申请人: Bernardus Hendrikus Wilhelmus Hendriks , Nicolaas Jan Noordhoek , Gerhardus Wilhelmus Lucassen , Pieter Maria Mielekamp , Rami Nachabé , Marjolein Van Der Voort , Waltherus Cornelis Jozef Bierhoff
发明人: Bernardus Hendrikus Wilhelmus Hendriks , Nicolaas Jan Noordhoek , Gerhardus Wilhelmus Lucassen , Pieter Maria Mielekamp , Rami Nachabé , Marjolein Van Der Voort , Waltherus Cornelis Jozef Bierhoff
CPC分类号: A61B34/10 , A61B18/14 , A61B2018/00577 , A61B2034/101
摘要: The invention relates to an energy application planning apparatus for planning an application of energy to an object (3) like a tumor. An energy application element representation represents an energy application element (5) like an ablation needle including an energy application part for applying energy and a sensing part (7). An arrangement of the energy application element (5) with respect to the object (3) is determined depending on the positions of the energy application part and the sensing part (7) with respect to the energy application element (5) as defined by the energy application element representation and depending on the object representation. The application of energy can therefore not only be planned such that the application of energy is performed as desired, but also such that the object and/or a surrounding of the object are sensible as desired. In this way, the planning procedure can be improved.
摘要翻译: 本发明涉及一种能量应用计划装置,用于规划能量到诸如肿瘤的物体(3)的应用。 能量应用元件表示代表诸如包括用于施加能量的能量施加部分和感测部分(7)的消融针的能量施加元件(5)。 能量施加元件(5)相对于物体(3)的布置根据能量施加部分和感测部分(7)相对于能量施加元件(5)的位置来确定,如由 能量应用元素表示,并取决于对象表示。 因此,能量的施加不仅可以被规划,使得能量的应用按照需要执行,而且还使得物体和/或物体的周围是期望的。 这样可以提高规划程序。
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