公开(公告)号：US20090088566A1

公开(公告)日：2009-04-02

申请号：US12280781

申请日：2006-10-16

申请人： Weichuan Lu ,  Qian Zhang ,  Xin Cheng

发明人： Weichuan Lu ,  Qian Zhang ,  Xin Cheng

IPC分类号： C07D205/08

CPC分类号： C07D205/08 ,  C07F7/188

摘要： The present invention discloses the usage of Poly-3-hydroxybutyrates P(3HB) in preparation of β-lactam compounds and the method for the preparation of β-lactam compounds of formula (I) using Poly-3-hydroxybutyrates P(3HB) as followed: wherein: R is R1, R2, R3 are lower linear or branched C1-C4 alkyl. It is convenient to synthesize the said compound of formula (I) with the present method. Compared with the previous ones, the present method has less steps and higher yields. Meanwhile, it also avoids the use of the reagents of the environmental for pollution and high cost, so as to reduce the cost and pollution

摘要翻译： 本发明公开了聚-3-羟基丁酸酯P（3HB）在制备β-内酰胺化合物中的用途以及使用聚-3-羟基丁酸酯P（3HB）作为制备式（I）的β-内酰胺化合物的方法 其中：R为R 1，R 2，R 3为低级直链或支链C 1 -C 4烷基。 以本方法合成所述式（I）化合物是方便的。 与以前的方法相比，本方法具有较少的步骤和较高的收率。 同时也避免了环境污染物的使用和成本高昂，从而降低成本和污染

公开(公告)号：US07985857B2

公开(公告)日：2011-07-26

申请号：US12280781

申请日：2006-10-16

申请人： Weichuan Lu ,  Qian Zhang ,  Xin Cheng

发明人： Weichuan Lu ,  Qian Zhang ,  Xin Cheng

IPC分类号： C07D205/08 ,  C07F7/18

CPC分类号： C07D205/08 ,  C07F7/188

摘要： A method for preparing compounds having the formula(I) by using P(3HB), wherein R is R1, R2, R3 are lower linear or branched C1-C4 alkyl, comprising the steps of: a: obtaining (3R)-3-RO—CH(CH3)CH2COOCH3 by pyrolysis of P(3HB) and protection; b: obtaining (3R)-3-RO—CH(CH3)CH2CHO by reduction of (3R)-3-RO—CH(CH3)CH2COOCH3 ; c: enolizing (3R)-3-RO—CH(CH3)CH2CHO and then reacting with chlorosulfonyl isocyanate, at last getting the final product by reduction; wherein (3R)-3-RO—CH(CH3)CH2CHO is enolized by reacting (3R)-3-RO—CH(CH3)CH2CHO with isopropenyl acetate and p-toluenesulfonic acid by heating under reflux.

摘要翻译： 通过使用P（3HB）制备具有式（I）的化合物的方法，其中R为R 1，R 2，R 3为低级直链或支链C 1 -C 4烷基，包括以下步骤：a：获得（3R）-3- RO-CH（CH3）CH2COOCH3通过热解P（3HB）和保护; b：通过还原（3R）-3 -OR-CH（CH3）CH2COOCH3获得（3R）-3 -OR-CH（CH 3）CH 2 CHO; c：烯化（3R）-3 -OR-CH（CH 3）CH 2 CHO，然后与氯磺酰基异氰酸酯反应，最后通过还原得到最终产物; 其中通过在回流下加热使（3R）-3 -OR-CH（CH 3）CH 2 CHO与乙酸异丙烯酯和对甲苯磺酸反应来使（3R）-3 -OR-CH（CH 3）CH 2 CHO烯醇化。

公开(公告)号：US11149254B2

公开(公告)日：2021-10-19

申请号：US13506369

申请日：2012-04-13

申请人： Aladar A. Szalay ,  Nanhai G. Chen ,  Yong A. Yu ,  Qian Zhang

发明人： Aladar A. Szalay ,  Nanhai G. Chen ,  Yong A. Yu ,  Qian Zhang

IPC分类号： C12N7/00 ,  A61K35/768 ,  C07K16/22

摘要： Clonal strains of vaccinia viruses are provided. Also provided are methods of identifying and isolating attenuated and oncolytic clonal strains from virus preparations. Modified recombinant forms of the clonal strains also are provided. The clonal strains and virus preparations can be used for diagnostic and therapeutic methods, in particular for therapy and diagnosis or monitoring treatment of proliferative disorders, including neoplastic diseases, such as, but are not limited to, solid tumors and blood cancers.

公开(公告)号：US09231709B2

公开(公告)日：2016-01-05

申请号：US13582734

申请日：2011-03-30

申请人： Kaishun Wu ,  Qian Zhang ,  Lionel Ming Shuan Ni

发明人： Kaishun Wu ,  Qian Zhang ,  Lionel Ming Shuan Ni

IPC分类号： H04B14/02 ,  H04J3/16

CPC分类号： H04B14/026 ,  H04B14/02 ,  H04J3/1676

摘要： Systems, methods, and apparatus are described that employ specially designed interference patterns to build an in-band side channel without degrading the effective throughput of the main channel. A first device (100) includes a control component (130) that generates control information and an interference component (140) that transmits the control information (450) through emission of patterned interference data concurrently while other users are transmitting other data (420). A second device (300) receives the patterned interference data and the other data via a single antenna (350) and decodes the patterned interference data to extract the control data (450). The first device (100) transmits the other data (420) on a side channel (440) that resides in the same spectrum as the main channel (410) in which the other data (420) is emitted. The first device (100) encodes the interference patterns such that the control data (450) can be safely transmitted and extracted without effecting other data transmission. In one aspect, devices (100, 200, 300) can employ a dynamic cooperation multi-access channel (DC-MAC) protocol (1510) to schedule transmission of the other data (420) on the main channel (410), and to employ the side channel (440) for control and coordination.

摘要翻译： 描述了采用专门设计的干扰模式来构建带内侧信道而不降低主信道的有效吞吐量的系统，方法和装置。 第一设备（100）包括产生控制信息的控制组件（130）和通过在其他用户正在发送其他数据的同时发射图案化干扰数据来发送控制信息（450）的干扰组件（140）（420）。 第二设备（300）经由单个天线（350）接收图案化的干扰数据和其它数据，并解码图案化的干扰数据以提取控制数据（450）。 第一设备（100）在与发送其他数据（420）的主信道（410）相同的频谱的侧信道（440）上发送其他数据（420）。 第一设备（100）对干扰图案进行编码，使得可以安全地传输和提取控制数据（450）而不影响其他数据传输。 在一个方面，设备（100,200,300）可以使用动态协作多址信道（DC-MAC）协议（1510）来调度主信道（410）上的其他数据（420）的传输，并且 使用侧信道（440）进行控制和协调。

公开(公告)号：US09161111B2

公开(公告)日：2015-10-13

申请号：US13645323

申请日：2012-10-04

申请人： Xiaotao Yuan ,  Qian Zhang ,  Hongyan Lu

发明人： Xiaotao Yuan ,  Qian Zhang ,  Hongyan Lu

IPC分类号： H04B3/00 ,  H04R1/02 ,  F21V33/00

CPC分类号： H04R1/023 ,  F21V33/0052 ,  F21V33/0056 ,  H04R1/026 ,  H04R1/028 ,  H04R2201/021 ,  H04R2420/07

摘要： Disclosed is a wireless speaker having a structure with the outer cover. The outer cover can be easily detached from the speaker body, facilitating user's mounting external electronic products as desired, for example, various types of bulbs, such as an LED or energy-saving lamp, and a wireless router or a camera. Also disclosed is a wireless speaker system, where the wireless set and the wireless speaker use wireless transmitting and receiving modules, or may use WiFi, Bluetooth or other wireless transmission modes. The wireless set supports a plurality of wireless speakers, and the wireless receiving speaker may be mounted on the ceiling, wall, or hidden place in a kitchen, living room, bedroom, bathroom or even bar, and restaurant; or even mounted on a table or floor lamp, or transportation means such as trains and planes, serving as a video and audio center for households and entertainment places by free combinations.

摘要翻译： 公开了一种具有外盖结构的无线扬声器。 外盖可以容易地从扬声器主体分离，便于用户根据需要安装外部电子产品，例如各种类型的灯泡，例如LED或节能灯，以及无线路由器或照相机。 还公开了一种无线扬声器系统，其中无线电设备和无线扬声器使用无线发射和接收模块，或者可以使用WiFi，蓝牙或其他无线传输模式。 无线机支撑多个无线扬声器，无线接收扬声器可以安装在厨房，客厅，卧室，浴室甚至酒吧和餐厅的天花板，墙壁或隐藏处; 甚至安装在桌面或落地灯上，或搭载火车和飞机的运输工具，作为家庭和娱乐场所的视频和音频中心，通过自由组合。

公开(公告)号：US08861496B2

公开(公告)日：2014-10-14

申请号：US13619222

申请日：2012-09-14

申请人： Yijun Yu ,  Qian Zhang

发明人： Yijun Yu ,  Qian Zhang

IPC分类号： H04W4/00 ,  H04W76/06 ,  H04W24/00

CPC分类号： H04W60/06 ,  H04W36/0022 ,  H04W36/14 ,  H04W76/30 ,  H04W76/32 ,  H04W76/34

摘要： A method and device for detaching a user equipment (UE) are disclosed in the present invention. The UE is registered with a mobility management entity (MME) in a packet switched (PS) network and a mobile switching center (MSC) in a circuit switched (CS) network. When the UE needs to detach from the PS network, the MSC receives a Detach Request with a Detach Type indicating the detaching from the PS network only; after receiving the Detach Request, the MSC deletes the context of the PS core network entity and clears the connection between the MSC and the MME. An MME for performing UE detachment is also disclosed in the present invention. The present invention helps reduce the time delay during the subsequent handover and quickly provide users with communications services, so as to improve user's experience and meet the carriers' requirements.

摘要翻译： 在本发明中公开了一种用于分离用户设备（UE）的方法和设备。 UE被分配交换（PS）网络中的移动性管理实体（MME）和电路交换（CS）网络中的移动交换中心（MSC））注册。 当UE需要从PS网络分离时，MSC接收到具有分离类型的分离请求，指示仅从PS网络分离; MSC收到分离请求后，删除PS核心网实体的上下文，并清除MSC与MME之间的连接。 在本发明中还公开了用于执行UE分离的MME。 本发明有助于减少后续切换期间的时延，并迅速为用户提供通信服务，从而提高用户体验并满足运营商的需求。

公开(公告)号：US20140087362A1

公开(公告)日：2014-03-27

申请号：US13815727

申请日：2013-03-13

申请人： Aladar A. Szalay ,  Nanhai G. Chen ,  Huiqiang Wang ,  Melody Fells ,  Albert Roeder ,  Qian Zhang ,  Boris Minev

发明人： Aladar A. Szalay ,  Nanhai G. Chen ,  Huiqiang Wang ,  Melody Fells ,  Albert Roeder ,  Qian Zhang ,  Boris Minev

IPC分类号： C12Q1/70

CPC分类号： C12Q1/701 ,  A61K38/00 ,  C07K14/00 ,  C07K16/28 ,  C07K2317/34 ,  C07K2319/00 ,  C12N2710/24132 ,  C12N2710/24162 ,  C12N2710/24171 ,  G01N33/57496 ,  G01N2800/52

摘要： Diagnostic methods for in vivo and ex vivo detection of circulating tumor cells (CTCs) for the diagnosis and treatment of cancer are provided. The diagnostic methods employ oncolytic viruses alone or in combination with one or more tumor cell enrichment and/or detection methods. Combinations and kits for use in the practicing the methods also are provided.

摘要翻译： 提供了用于诊断和治疗癌症的循环肿瘤细胞（CTC）的体内和体外检测的诊断方法。 诊断方法单独使用溶瘤病毒或与一种或多种肿瘤细胞富集和/或检测方法组合使用。 还提供了用于实施该方法的组合和试剂盒。

公开(公告)号：US08675887B2

公开(公告)日：2014-03-18

申请号：US12874905

申请日：2010-09-02

申请人： Xiaotao Yuan ,  Qian Zhang ,  Hongyan Lu

发明人： Xiaotao Yuan ,  Qian Zhang ,  Hongyan Lu

IPC分类号： H04B3/00 ,  H04R5/02

CPC分类号： F21V33/0056 ,  H04R1/028 ,  H04R2201/021 ,  H04R2420/07

摘要： A wireless illuminative speaker system, comprising a wireless transmitter comprising a transmitter body, a wireless transmit module, a main board printed board circuit assembly (PCBA), and a support, and at least one wireless illuminative receiving speaker comprising a speaker body, an illuminating part, a speaker part, and a wireless receiving module. The wireless transmitter operates to obtain audio data from an external electronic device and to transmit the audio data in the form of wireless audio digital signals, the wireless transmit module is disposed in the transmitter body, the main board PCBA operates to control the wireless transmit module, the support operates to mount an audio playing device thereon, the wireless illuminative receiving speaker operates to receive the wireless audio digital signals from the wireless transmitter and to plays the received wireless audio digital signals after digital-to-analog conversion, and the illuminating part is disposed in the speaker body.

摘要翻译： 一种无线照明扬声器系统，包括：无线发射器，包括发射器主体，无线发射模块，主板印刷电路板组件（PCBA）和支架;以及至少一个无线照明接收扬声器，包括扬声器主体，照明 部分，扬声器部分和无线接收模块。 无线发射机操作以从外部电子设备获得音频数据，并以无线音频数字信号的形式发送音频数据，无线发射模块设置在发射机主体中，主板PCBA操作以控制无线发射模块 支持操作以在其上安装音频播放设备，无线照明接收扬声器操作以从无线发射器接收无线音频数字信号，并且在数模转换之后播放接收到的无线音频数字信号，并且照明部分 设置在扬声器主体中。

公开(公告)号：US20140003711A1

公开(公告)日：2014-01-02

申请号：US13539046

申请日：2012-06-29

申请人： King Ngi Ngan ,  Chunhui Cui ,  Qian Zhang ,  Songnan Li

发明人： King Ngi Ngan ,  Chunhui Cui ,  Qian Zhang ,  Songnan Li

IPC分类号： G06K9/34

CPC分类号： G06T7/174 ,  G06T7/11 ,  G06T7/136 ,  G06T7/194 ,  G06T2207/10016 ,  G06T2207/10024 ,  H04N2013/0081 ,  H04N2013/0092

摘要： Subject matter disclosed herein relates to foreground image extraction and image depth of video images.

摘要翻译： 本文公开的主题涉及视频图像的前景图像提取和图像深度。

公开(公告)号：US08619712B2

公开(公告)日：2013-12-31

申请号：US12971612

申请日：2010-12-17

申请人： Yijun Yu ,  Qian Zhang

发明人： Yijun Yu ,  Qian Zhang

IPC分类号： H04W4/00 ,  H04W40/00 ,  H04M1/00

CPC分类号： H04W60/06 ,  H04W36/0022 ,  H04W36/14 ,  H04W76/30 ,  H04W76/32 ,  H04W76/34

摘要： A method and device for detaching a user equipment (UE) are disclosed in the present invention. The UE is registered with a mobility management entity (MME) in a packet switched (PS) network and a mobile switching center (MSC) in a circuit switched (CS) network. When the UE needs to detach from the PS network, the MSC receives a Detach Request with a Detach Type indicating the detaching from the PS network only; after receiving the Detach Request, the MSC deletes the context of the PS core network entity and clears the connection between the MSC and the MME. An MME for performing UE detachment is also disclosed in the present invention. The present invention helps reduce the time delay during the subsequent handover and quickly provide users with communications services, so as to improve user's experience and meet the carriers' requirements.

摘要翻译： 在本发明中公开了一种用于分离用户设备（UE）的方法和设备。 UE被分配交换（PS）网络中的移动性管理实体（MME）和电路交换（CS）网络中的移动交换中心（MSC））注册。 当UE需要从PS网络分离时，MSC接收到具有分离类型的分离请求，指示仅从PS网络分离; MSC收到分离请求后，删除PS核心网实体的上下文，并清除MSC与MME之间的连接。 在本发明中还公开了用于执行UE分离的MME。 本发明有助于减少后续切换期间的时延，并迅速为用户提供通信服务，从而提高用户体验并满足运营商的需求。