公开(公告)号：US20100210822A1

公开(公告)日：2010-08-19

申请号：US12676766

申请日：2008-09-04

申请人： Wenbing Yao ,  Hong Tian ,  Xiangyang Xu ,  Hairui Li ,  Yue Dong ,  Xiangdong Gao

发明人： Wenbing Yao ,  Hong Tian ,  Xiangyang Xu ,  Hairui Li ,  Yue Dong ,  Xiangdong Gao

IPC分类号： C07K14/78

CPC分类号： C07K14/78 ,  A61K38/00 ,  A61K47/48215 ,  A61K47/60

摘要： Provided is a kind of modified recombinant human endostatin that has the structure of CH3O—(CH2CH2O)m—CH2CH2CH2—NαH-Endostar, wherein the average molecular weight of CH3O—(CH2CH2O)m—CH2CH2CH2— is 20-40 kD. The modified recombinant human endostatin enhances the stability in vivo, improves blood drug concentration, prolongs half-life, markedly increases the activity of inhibiting the endothelial cells proliferation, thus reduces drug dosage and decreases administration frequency. Its application for preparing anti-tumor pharmaceutical compositions is also provided.

摘要翻译： 提供了一种具有CH3O-（CH2CH2O）m-CH2CH2CH2-NαH-Endostar结构的一种修饰的重组人内皮抑素，其中CH 3 O-（CH 2 CH 2 O）m -CH 2 CH 2 CH 2的平均分子量为20-40kD。 修饰的重组人内皮抑素增强体内的稳定性，改善血药浓度，延长半衰期，显着增加抑制内皮细胞增殖的活性，从而降低药物用量，降低给药频率。 还提供其制备抗肿瘤药物组合物的应用。

公开(公告)号：US08802824B2

公开(公告)日：2014-08-12

申请号：US12676766

申请日：2008-09-04

申请人： Wenbing Yao ,  Hong Tian ,  Xiangyang Xu ,  Hairui Li ,  Yue Dong ,  Xiangdong Gao

发明人： Wenbing Yao ,  Hong Tian ,  Xiangyang Xu ,  Hairui Li ,  Yue Dong ,  Xiangdong Gao

IPC分类号： A61K38/17 ,  C07K14/78 ,  A61K47/48 ,  A61K38/00

CPC分类号： C07K14/78 ,  A61K38/00 ,  A61K47/48215 ,  A61K47/60

摘要： Provided is a kind of modified recombinant human endostatin that has the structure of CH3O—(CH2CH2O)m—CH2CH2CH2—NαH-Endostar, wherein the average molecular weight of CH3O—(CH2CH2O)m—CH2CH2CH2— is 20-40 kD. The modified recombinant human endostatin enhances the stability in vivo, improves blood drug concentration, prolongs half-life, markedly increases the activity of inhibiting the endothelial cells proliferation, thus reduces drug dosage and decreases administration frequency. Its application for preparing anti-tumor pharmaceutical compositions is also provided.

摘要翻译： 提供了一种具有CH3O-（CH2CH2O）m-CH2CH2CH2-NαH-Endostar结构的一种修饰的重组人内皮抑素，其中CH 3 O-（CH 2 CH 2 O）m -CH 2 CH 2 CH 2的平均分子量为20-40kD。 修饰的重组人内皮抑素增强体内的稳定性，改善血药浓度，延长半衰期，显着增加抑制内皮细胞增殖的活性，从而降低药物用量，降低给药频率。 还提供其制备抗肿瘤药物组合物的应用。

公开(公告)号：US09230233B1

公开(公告)日：2016-01-05

申请号：US13247838

申请日：2011-09-28

申请人： Subramanian Sundaresan ,  Abhay Murarka ,  Sebastian Lehmann ,  Rohit K. Gupta ,  Hong Tian

发明人： Subramanian Sundaresan ,  Abhay Murarka ,  Sebastian Lehmann ,  Rohit K. Gupta ,  Hong Tian

IPC分类号： G06Q10/00 ,  G06Q10/08 ,  G06Q50/30

CPC分类号： G06Q10/08345 ,  G06Q10/0832 ,  G06Q50/30

摘要： The systems described herein may provide mechanisms for recommending specialty packaging in a materials handling facility dependent on physical characteristics of items to be shipped and/or feedback received in response to previous shipments of the items. For example, if feedback indicates frequent low customer ratings for damage during shipping and/or for the suitability of the container in which a particular item was shipped, of if feedback indicates that concession costs were repeatedly incurred due to damage of the item during shipping, the item may be designated as needing special damage protection. This protection may be realized by shipping the item in sturdier containers, in containers of a more suitable size, and/or with improved or increased protective cushioning. For example, a stored indication that an item is designated for special damage protection may influence the selection of a container recommended for shipping the item, e.g., by excluding unsuitable containers from consideration.

摘要翻译： 本文所述的系统可以提供用于根据物品的物理特性来推荐特定包装在物料处理设备中的机制，并且/或响应于先前的物品运送而接收到的反馈。 例如，如果反馈意味着在运输过程中和/或特定物品运送时的容器的适用性反映频繁的低客户评级，如果反馈表明由于运输过程中物品损坏而重复出现特许成本， 该物品可能被指定为需要特殊的损坏保护。 这种保护可以通过将物品运送在更坚固的容器中，以更合适的尺寸的容器和/或具有改进或增加的保护性缓冲的容器中来实现。 例如，存储的指示物品被指定用于特殊损伤保护可能会影响对推荐用于运输物品的容器的选择，例如通过从考虑中排除不合适的容器。

公开(公告)号：US08340812B1

公开(公告)日：2012-12-25

申请号：US11847735

申请日：2007-08-30

申请人： Hong Tian ,  Mackenzie Smith ,  Devesh Mishra

发明人： Hong Tian ,  Mackenzie Smith ,  Devesh Mishra

IPC分类号： G06F7/00

CPC分类号： G06Q10/083 ,  B65B65/08 ,  G06Q10/04

摘要： Various systems, methods, and programs embodied in computer-readable mediums are provided for determining optimum sizes of packaging in a packaging suite employed in a materials handling facility. The packaging may be used, for example, in the shipping of items from the materials handling facility to various destinations. The sizes of the packaging in the packaging suite are determined based upon the shipping volumes associated with packages or shipments shipped from the materials handling facility.

摘要翻译： 提供了包含在计算机可读介质中的各种系统，方法和程序，用于确定在材料处理设施中使用的包装套件中的包装的最佳尺寸。 包装可以用于例如从物料搬运设施运送到各种目的地的物品。 包装套件中的包装尺寸根据与从物料搬运设施运送的包装或运输相关的运输量确定。

公开(公告)号：US08045295B2

公开(公告)日：2011-10-25

申请号：US12145464

申请日：2008-06-24

申请人： Yen Fu ,  Ellis T. Cha ,  Po-Kang Wang ,  Hong Tian ,  Manuel Hernandez ,  Yaw-Shing Tang ,  Ben Hu

发明人： Yen Fu ,  Ellis T. Cha ,  Po-Kang Wang ,  Hong Tian ,  Manuel Hernandez ,  Yaw-Shing Tang ,  Ben Hu

IPC分类号： G11B5/55

CPC分类号： H05K3/3442 ,  B24B37/00 ,  B24D18/00 ,  G11B5/4853 ,  H05K1/0215 ,  H05K2201/10727 ,  Y02P70/613

摘要： Method and apparatus are presented for electrically coupling a slider to ground. In one embodiment, a bonding pad is provided on a side of the slider body separate from the bonding pad(s) used for read/write signals. This separate bonding pad is electrically coupled within the slider body to components that are to be coupled to ground. A separate conductor provided on the suspension (e.g., a trace, a flex circuit, etc.) may be electrically coupled to the separate bonding pad via gold ball bonding. The conductor is also coupled to ground in the hard-disk drive device (e.g., via the preamplifier). The use of the separated bonding pad and trace may negate the need to use a conductive adhesive to electrically ground the slider via its attachment to the tongue of a slider.

摘要翻译： 呈现用于将滑块电耦合到地面的方法和装置。 在一个实施例中，接合焊盘设置在与用于读/写信号的接合焊盘分开的滑块体的一侧上。 该单独的接合焊盘在滑块体内电耦合到要耦合到地面的部件。 设置在悬架上的单独的导体（例如，迹线，柔性电路等）可以通过金球接合电耦合到单独的接合焊盘。 导体也耦合到硬盘驱动装置中的接地（例如，经由前置放大器）。 使用分离的接合焊盘和迹线可能会使得不需要使用导电粘合剂来将滑块经由其附接件电连接到滑块的舌部。

公开(公告)号：US20080202036A1

公开(公告)日：2008-08-28

申请号：US11842823

申请日：2007-08-21

申请人： Guo Qiang Zheng ,  Jia Bing Shen ,  Yu Li ,  Hong Tian

发明人： Guo Qiang Zheng ,  Jia Bing Shen ,  Yu Li ,  Hong Tian

IPC分类号： B24D18/00 ,  B24D11/00 ,  B24B1/00

CPC分类号： B24B37/046 ,  B24B7/228 ,  G11B5/455 ,  G11B5/82 ,  G11B5/8404 ,  G11B23/505

摘要： A system and method for treating (e.g. polishing to remove defects) the surface of a media, such as a magnetic hard disk, while in operation, such as during dynamic electrical testing is disclosed. Further, a method for manufacturing a head for treating the surface of a media is disclosed.

摘要翻译： 公开了在动态电气测试期间在操作中处理（例如抛光以消除缺陷）的媒体例如磁性硬盘的表面的系统和方法。 此外，公开了一种用于制造用于处理介质表面的头部的方法。

公开(公告)号：US20070217894A1

公开(公告)日：2007-09-20

申请号：US11580704

申请日：2006-10-13

申请人： Hong Tian ,  Xiaqi Wang

发明人： Hong Tian ,  Xiaqi Wang

IPC分类号： B65G67/60

CPC分类号： B65G63/025

摘要： The present invention discloses a container transportation carrier comprising: a bottom frame; a set of wheels, mounted on said bottom frame, said set of wheels being positioned on a set of tracks so that said container transportation carrier travels along the tracks; wheel driving means, mounted on said bottom frame, for driving said set of wheels; rotary mechanism, mounted on said bottom frame, being rotatable with respect to said bottom frame; a rotary platform, spanned on said rotary mechanism by rotary supporting means, with containers positioned on said rotary platform; rotary driving means, mounted on said bottom frame, for driving said rotary mechanism to rotate said rotary platform. The present invention also discloses a container transportation system and a whole arrangement scheme of container wharf using the above transportation carrier. Using the technical solutions of the present invention, the speed of transportation between cranes at shore of container wharf and ones at the container yard will be significantly increased and the problem of 90-degree rotation will be solved. In addition, the handling way can be used at non-automatic wharfs, and, preferably, at automatic wharfs. The advantage of efficient handling is to enhance efficiency and technical level of the container handling port.

摘要翻译： 本发明公开了一种集装箱运输载体，包括：底架; 安装在所述底架上的一组轮子，所述一组车轮定位在一组轨道上，使得所述集装箱运输托架沿轨道行进; 车轮驱动装置，安装在所述底架上，用于驱动所述一组车轮; 旋转机构，安装在所述底架上，可相对于所述底架旋转; 旋转平台，通过旋转支撑装置跨越所述旋转机构，具有位于所述旋转平台上的容器; 旋转驱动装置，安装在所述底架上，用于驱动所述旋转机构以旋转所述旋转平台。 本发明还公开了使用上述运输工具的集装箱码头的集装箱运输系统和整体布置方案。 利用本发明的技术方案，集装箱码头岸上的起重机与集装箱码头的起重机运输速度将显着增加，解决90度旋转的问题。 此外，处理方式可用于非自动码头，最好在自动码头使用。 有效处理的优点是提高集装箱处理口的效率和技术水平。

公开(公告)号：US5497085A

公开(公告)日：1996-03-05

申请号：US358282

申请日：1994-12-19

申请人： Hong Tian ,  Jia-Kuen J. Lee ,  Ellis T. Cha

发明人： Hong Tian ,  Jia-Kuen J. Lee ,  Ellis T. Cha

IPC分类号： G11B21/21 ,  G11B5/60 ,  G11B5/84

CPC分类号： G11B5/6005

摘要： A method is shown for testing a magnetic disk to be used in a disk drive. The method includes the steps of measuring a height profile of an outer radial edge of the disk, using the profile to determine a slope value for each of a pair of radial segments of the disk, calculating a difference value between the slope values of the pair, comparing the difference value to a preselected threshold difference value and indicating when the difference value is equal to or less than the threshold difference value. The threshold value indicates an outer most diameter of the disk where fly height operation for a head is still stable.

摘要翻译： 显示了一种用于测试在磁盘驱动器中使用的磁盘的方法。 该方法包括以下步骤：使用轮廓来测量盘的外径向边缘的高度轮廓，以确定盘的一对径向段中的每一个的斜率值，计算该对的斜率值之间的差值 将差分值与预先选择的阈值差值进行比较，并指示差值等于或小于阈值差值。 阈值表示磁头的飞行高度操作仍然稳定的磁盘的最外径。

公开(公告)号：US08401975B1

公开(公告)日：2013-03-19

申请号：US11744336

申请日：2007-05-04

申请人： Hong Tian ,  Devesh Mishra ,  Mackenzie Smith ,  James E. Bacus

发明人： Hong Tian ,  Devesh Mishra ,  Mackenzie Smith ,  James E. Bacus

IPC分类号： G06Q99/00

CPC分类号： G06Q10/08

摘要： A computer-implemented method for analyzing package performance in a materials handling facility may include calculating an expected shipping cost for an item package and an actual shipping cost for the item package to determine excess shipping costs due to shipping item packages in the wrong container. The expected shipping cost may be the sum of the transportation cost and shipping materials cost when the item package is shipped in a recommended container. The actual shipping cost may be the sum of the transportation cost and shipping materials cost when the item is shipped in another container. The shipping materials costs may include the costs of the containers themselves and any non-item contents in the containers. A package performance analyzer may be configured to calculate excess shipping costs, generate various package performance reports according to received report parameters, and recommend corrective actions, including changing the available container types or providing training.

摘要翻译： 用于分析材料处理设施中的包装性能的计算机实现的方法可以包括计算物品包裹的预期运输成本和物品包裹的实际运输成本，以确定由于错误的容器中的运输物品包裹而导致的超出运送费用。 预期的运输成本可能是在推荐的集装箱中运送物品包裹时的运输成本和运输材料成本的总和。 实际运输成本可能是货物在另一个集装箱中运输时的运输成本和运输成本的总和。 运输材料成本可能包括集装箱本身的成本和集装箱中的任何非物品内容。 可以将包装性能分析器配置为计算超额运输成本，根据接收到的报告参数生成各种包装性能报告，并建议纠正措施，包括更改可用的容器类型或提供培训。

公开(公告)号：US08087867B2

公开(公告)日：2012-01-03

申请号：US12356113

申请日：2009-01-20

申请人： Hong Tian

发明人： Hong Tian

IPC分类号： B66C19/00 ,  B65G63/00

CPC分类号： B65G63/004 ,  B66C19/002

摘要： Embodiments of the present invention include quayside cranes and yard cranes related by a low elevated transfer system and a ground transportation carrier system. The low elevated transfer system includes low elevated transfer subsystems having low elevated rails, the low elevates rails include low elevated crane rails and low elevated flat carrier rails, low elevated cranes are disposed on the low elevated crane rails and low elevated flat carriers are disposed on the low elevated flat carrier rail. The ground transportation carrier system includes ground transportation carrier rails and transportation carriers moving along the ground transportation carrier rails. Embodiments of the present invention transport the containers by rails and use municipal electric as the power supply. A three-dimensional low elevated transfer system and a ground transportation carrier system are provided to implement three-dimensional transportation of containers. Embodiments of the present invention provide a container transportation schema that is efficient, power saving, environmental and automatic, ground resources are utilized with high efficiency. The present invention is an expansion and development of the invention provided in CN 200510111464.0.

摘要翻译： 本发明的实施例包括由低升高的传送系统和地面运输载体系统相关的码头起重机和码头起重机。 低升高的转移系统包括具有低升高轨道的低升高的运输子系统，低升降轨道包括低升高的起重机轨道和低升高的平板运输轨道，低高架起重机布置在低高架起重机轨道上，并且将低升高的平板运输机设置在 低架高架平板载轨。 地面运输承运人系统包括地面运输承载轨道和沿地面运输承载轨道运输的运输承运人。 本发明的实施例通过轨道运输容器并使用市电作为电源。 提供了一种三维低架转移系统和地面运输承载系统来实现集装箱的三维运输。 本发明的实施例提供了一种高效，节能，环保和自动的集装箱运输方案，高效率地利用了地面资源。 本发明是CN 200510111464.0中提供的本发明的扩展和发展。