-
公开(公告)号：US09778254B2
公开(公告)日：2017-10-03
申请号：US12669217
申请日：2008-07-18
申请人： Femke Karina De Theije , Thea Van Der Wijk , Albert Hendrik Jan Immink , Eduard Gerard Marie Pelssers , Wilhelmina Maria Hardeman , Sandra Marlin , Gordon Thomas Jowett
发明人： Femke Karina De Theije , Thea Van Der Wijk , Albert Hendrik Jan Immink , Eduard Gerard Marie Pelssers , Wilhelmina Maria Hardeman , Sandra Marlin , Gordon Thomas Jowett
IPC分类号： G01N27/74 , G01N33/543
CPC分类号： G01N33/54366 , G01N27/745 , Y10T29/49885
摘要： A system and method wherein components of a reagent such as labeled antibodies are separated from a biologically active sensor surface by depositing the reagent on a carrier surface distinct from a sensor surface in a detection region. The present device provides a short, well-defined and controlled, pre-incubation time between the particles of interest in the sample fluid and the reagent, thereby increasing the reproducibility by providing all components in one detection region such as a detection chamber.
-
公开(公告)号：US20100297780A1
公开(公告)日：2010-11-25
申请号：US12669217
申请日：2008-07-18
申请人： Femke Karina De Theije , Thea Van Der Wijk , Albert Hendrik Jan Immink , Eduard Gerard Marie Pelssers , Wilhelmina Maria Hardeman , Sandra Marlin , Gordon Thomas Jowett
发明人： Femke Karina De Theije , Thea Van Der Wijk , Albert Hendrik Jan Immink , Eduard Gerard Marie Pelssers , Wilhelmina Maria Hardeman , Sandra Marlin , Gordon Thomas Jowett
IPC分类号： G01N33/553 , G01N30/96 , B23P25/00
CPC分类号： G01N33/54366 , G01N27/745 , Y10T29/49885
摘要： A system and method is described wherein components of the reagent (4), e.g. labelled antibodies, are separated from the biologically active sensor surface (5) by depositing the reagent (4) on a carrier surface (3) distinct from the sensor surface (5) in the detection region (2), e.g. detection chamber. In this way, a high assay reproducibility is obtained. By allowing a short, well-defined and controlled, pre-incubation time between the particles of interest, e.g. drugs, in the sample fluid (20) and the reagent (4), the reproducibility will be increased, whereas the speed of the assay is guaranteed by having all components in one detection region (2), e.g. detection chamber.
摘要翻译： 描述了一种系统和方法，其中试剂（4）的组分例如。 通过将试剂（4）沉积在与检测区域（2）中的传感器表面（5）不同的载体表面（3）上，例如从生物活性传感器表面（5）分离。 检测室。 以这种方式，获得高的测定重现性。 通过在感兴趣的颗粒之间允许短的，明确的和受控的预孵育时间，例如。 药物在样品液体（20）和试剂（4）中的重现性将会增加，而测定的速度则通过在一个检测区域（2）中具有所有成分来保证。 检测室。
-
公开(公告)号：US09575081B2
公开(公告)日：2017-02-21
申请号：US14191043
申请日：2014-02-26
申请人： Jeroen Hans Nieuwenhuis , Ahmed Mohammed Taki Jehanli , Femke Karina De Theije , Eduard Gerard Marie Pelssers
发明人： Jeroen Hans Nieuwenhuis , Ahmed Mohammed Taki Jehanli , Femke Karina De Theije , Eduard Gerard Marie Pelssers
IPC分类号： G01N33/94 , B01L3/00 , G01N27/74 , G01N33/543
CPC分类号： G01N33/9486 , B01L3/502753 , G01N27/745 , G01N33/54326 , G01N33/54393 , G01N33/946
摘要： The invention provides a device for detecting drugs of abuse or other compounds in saliva. The invention thus provides a device for detecting the presence of one or more analytes in a saliva sample, comprising: (a) One or more pre-treatment regions for specifically or non-specifically removing at least a part of the fraction of the saliva sample interfering with detection of the one or more analytes; and (b) A detection region comprising a biosensor surface, the surface comprising: molecules capable of specifically binding the one or more analytes; or the one or more analytes and/or analyte analogues.
摘要翻译： 本发明提供了一种用于检测唾液中的药物或其他化合物的装置。 因此，本发明提供了一种用于检测唾液样品中一种或多种分析物的存在的装置，其包括：（a）用于特异性或非特异性地去除唾液样品的至少一部分部分的一个或多个预处理区域 干扰一种或多种分析物的检测; 和（b）包含生物传感器表面的检测区域，所述表面包括：能够特异性结合所述一种或多种分析物的分子; 或一种或多种分析物和/或分析物类似物。
-
公开(公告)号：US09103843B2
公开(公告)日：2015-08-11
申请号：US12993100
申请日：2009-05-26
申请人： Jeroen Hans Nieuwenhuis , Ahmed Mohammed Taki Jehanli , Femke Karina De Theije , Eduard Gerard Marie Pelssers
发明人： Jeroen Hans Nieuwenhuis , Ahmed Mohammed Taki Jehanli , Femke Karina De Theije , Eduard Gerard Marie Pelssers
IPC分类号： G01N33/543 , G01N33/94 , B01L3/00 , G01N27/74
CPC分类号： G01N33/9486 , B01L3/502753 , G01N27/745 , G01N33/54326 , G01N33/54393 , G01N33/946
摘要： The invention provides a device for detecting drugs of abuse or other compounds in saliva. The invention thus provides a device for detecting the presence of one or more analytes in a saliva sample, comprising: (a) One or more pre-treatment regions for specifically or non-specifically removing at least a part of the fraction of the saliva sample interfering with detection of the one or more analytes; and (b) A detection region comprising a biosensor surface, the surface comprising: molecules capable of specifically binding the one or more analytes; or the one or more analytes and/or analyte analogs.
摘要翻译： 本发明提供了一种用于检测唾液中的药物或其他化合物的装置。 因此，本发明提供了一种用于检测唾液样品中一种或多种分析物的存在的装置，其包括：（a）用于特异性或非特异性地去除唾液样品的至少一部分部分的一个或多个预处理区域 干扰一种或多种分析物的检测; 和（b）包含生物传感器表面的检测区域，所述表面包括：能够特异性结合所述一种或多种分析物的分子; 或一种或多种分析物和/或分析物类似物。
-
公开(公告)号：US20110065211A1
公开(公告)日：2011-03-17
申请号：US12993100
申请日：2009-05-26
申请人： Jeroen Hans Nieuwenhuis , Ahmed Mohammed Taki Jehanli , Femke Karina De Theije , Eduard Gerard Marie Pelssers
发明人： Jeroen Hans Nieuwenhuis , Ahmed Mohammed Taki Jehanli , Femke Karina De Theije , Eduard Gerard Marie Pelssers
IPC分类号： G01N33/566 , G01N30/00
CPC分类号： G01N33/9486 , B01L3/502753 , G01N27/745 , G01N33/54326 , G01N33/54393 , G01N33/946
摘要： The invention provides a device for detecting drugs of abuse or other compounds in saliva. The invention thus provides a device for detecting the presence of one or more analytes in a saliva sample, comprising: (a) One or more pre-treatment regions for specifically or non-specifically removing at least a part of the fraction of the saliva sample interfering with detection of the one or more analytes; and (b) A detection region comprising a biosensor surface, the surface comprising: molecules capable of specifically binding the one or more analytes; or the one or more analytes and/or analyte analogues.
摘要翻译： 本发明提供了一种用于检测唾液中的药物或其他化合物的装置。 因此，本发明提供了一种用于检测唾液样品中一种或多种分析物的存在的装置，其包括：（a）用于特异性或非特异性地去除唾液样品的至少一部分部分的一个或多个预处理区域 干扰一种或多种分析物的检测; 和（b）包含生物传感器表面的检测区域，所述表面包括：能够特异性结合所述一种或多种分析物的分子; 或一种或多种分析物和/或分析物类似物。
-
公开(公告)号：US20090117670A1
公开(公告)日：2009-05-07
申请号：US12299806
申请日：2007-04-27
IPC分类号： G01N33/543
CPC分类号： G01N33/54333 , G01N27/745 , G01N2446/00
摘要： The application relates to a method for detecting a target in a sample suspected of containing the target. The method comprises contacting the sample and a first binding molecule attached to a magnetic particle with a second binding molecule attached to a solid support. The first binding molecule is capable of binding to the second binding molecule, and the target is capable of interfering with this binding. Magnetic force is applied to bring the magnetic particle into close proximity with the solid support. The number of magnetic particles bound to the solid support is detected.
摘要翻译： 本申请涉及一种用于检测疑似含有靶标的样品中的靶标的方法。 该方法包括将样品和附着于磁性颗粒的第一结合分子与连接至固体支持物的第二结合分子接触。 第一结合分子能够结合第二结合分子，并且靶能够干扰该结合。 施加磁力以使磁性颗粒与固体支持物紧密接近。 检测与固体支持物结合的磁性颗粒的数量。
-
公开(公告)号：US20110100104A1
公开(公告)日：2011-05-05
申请号：US13000728
申请日：2009-06-22
CPC分类号： B01L3/502715 , A61B10/0045 , B01L3/5029 , B01L2200/027 , B01L2200/10 , B01L2200/16 , B01L2300/0636 , B01L2300/0816 , B01L2400/0406 , B01L2400/0481 , G01N2001/028
摘要： The present invention relates to a device (10, 110, 210) for sampling sample material for an analyte, comprising: a receiving swab (15, 115, 215, 315), wherein at least a portion (20, 120, 220) of the receiving swab is compressible; a sensor (25, 125, 225) for sensing the analyte; and a casing (30, 130, 230), wherein the casing at least partially encloses the receiving swab and the sensor and allows for a transfer of sample material received by the receiving swab to the sensor along a transfer path (35, 135, 235) inside of the casing; wherein the compressible portion (20, 120, 220) of the receiving swab is located inside the casing, wherein by compressing the compressible portion the transfer path is closable towards the outside of the device. The present invention further relates to a corresponding system and a corresponding method.
摘要翻译： 本发明涉及一种用于对分析物的样品材料进行取样的装置（10,110,210），包括：接收拭子（15,115,215,315），其中至少一部分（20,120,220）的 接收棉签是可压缩的; 用于感测分析物的传感器（25,125,225）; 以及壳体（30,130,230），其中所述壳体至少部分地包围所述接收拭子和所述传感器，并且允许将由所述接收棉签接收的样品材料沿着传送路径（35,135,235）传送到所述传感器 ）套管内; 其中所述接收拭子的可压缩部分（20,120,220）位于所述壳体内部，其中通过压缩所述可压缩部分，所述传送路径可朝向所述装置的外部封闭。 本发明还涉及相应的系统和相应的方法。
-
公开(公告)号：US08770049B2
公开(公告)日：2014-07-08
申请号：US13000728
申请日：2009-06-22
CPC分类号： B01L3/502715 , A61B10/0045 , B01L3/5029 , B01L2200/027 , B01L2200/10 , B01L2200/16 , B01L2300/0636 , B01L2300/0816 , B01L2400/0406 , B01L2400/0481 , G01N2001/028
摘要： A device, system and method for sampling sample material for an analyte including a receiving swab, wherein at least a portion of the receiving swab is compressible; a sensor for sensing the analyte; and a casing, wherein the casing at least partially encloses the receiving swab and the sensor and allows for a transfer of sample material received by the receiving swab to the sensor along a transfer path inside of the casing. The compressible portion of the receiving swab is located inside the casing, wherein by compressing the compressible portion, the transfer path is closable towards the outside of the device.
摘要翻译： 一种用于对包括接收拭子的分析物的样品材料进行采样的装置，系统和方法，其中所述接收拭子的至少一部分是可压缩的; 用于感测分析物的传感器; 以及壳体，其中所述壳体至少部分地包围所述接收拭子和所述传感器，并允许沿着所述壳体内部的传送路径将由所述接收棉签接收的样品材料传送到所述传感器。 接收拭子的可压缩部分位于壳体内部，其中通过压缩可压缩部分，传送路径可朝向装置的外部封闭。
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.037 秒)
