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12 条记录 (耗时 0.035 秒)

    Opto-acoustic transducer for medical applications
    1.
    发明授权
    Opto-acoustic transducer for medical applications 失效
    用于医疗应用的光学传感器

    公开(公告)号：US06379325B1

    公开(公告)日：2002-04-30

    申请号：US09350494

    申请日：1999-07-09

    申请人： William Benett ,  Peter Celliers ,  Luiz Da Silva ,  Michael Glinsky ,  Richard London ,  Duncan Maitland ,  Dennis Matthews ,  Peter Krulevich ,  Abraham Lee

    发明人： William Benett ,  Peter Celliers ,  Luiz Da Silva ,  Michael Glinsky ,  Richard London ,  Duncan Maitland ,  Dennis Matthews ,  Peter Krulevich ,  Abraham Lee

    IPC分类号： A61B1720

    CPC分类号： A61B18/26 ,  A61B17/2202 ,  A61B2017/00106 ,  A61B2017/22084 ,  A61B2090/378

    摘要： This invention is an optically activated transducer for generating acoustic vibrations in a biological medium. The transducer is located at the end of a fiber optic which may be located within a catheter. Energy for operating the transducer is provided optically by laser light transmitted through the fiber optic to the transducer. Pulsed laser light is absorbed in the working fluid of the transducer to generate a thermal pressure and consequent adiabatic expansion of the transducer head such that it does work against the ambient medium. The transducer returns to its original state by a process of thermal cooling. The motion of the transducer within the ambient medium couples acoustic energy into the medium. By pulsing the laser at a high repetition rate (which may vary from CW to 100 kHz) an ultrasonic radiation field can be established locally in the medium. This method of producing ultrasonic vibrations can be used in vivo for the treatment of stroke-related conditions in humans, particularly for dissolving thrombus. The catheter may also incorporate anti-thrombolytic drug treatments as an adjunct therapy and it may be operated in conjunction with ultrasonic detection equipment for imaging and feedback control.

    摘要翻译： 本发明是用于在生物介质中产生声振动的光学激活换能器。 传感器位于可以位于导管内的光纤的端部。 用于操作换能器的能量由通过光纤传输到换能器的激光光学地提供。 脉冲激光被吸收在换能器的工作流体中，以产生热压力并随之导致换能器头部的绝热膨胀，使其对环境介质起作用。 传感器通过热冷却过程返回到其原始状态。 传感器在环境介质中的运动将声能耦合到介质中。 通过以高重复率脉冲激光（其可以从CW变化到100kHz），可以在介质中局部地建立超声辐射场。 这种生产超声波振动的方法可以在体内用于治疗人类中风相关病症，特别是用于溶解血栓。 导管还可以掺入抗血栓溶解药物治疗作为辅助治疗，并且其可以与用于成像和反馈控制的超声波检测设备结合操作。

    Photoacoustic removal of occlusions from blood vessels
    4.
    发明申请
    Photoacoustic removal of occlusions from blood vessels 审中-公开
    光声消除血管闭塞

    公开(公告)号：US20050021013A1

    公开(公告)日：2005-01-27

    申请号：US10241741

    申请日：2002-09-10

    申请人： Steven Visuri ,  Luiz Da Silva ,  Peter Celliers ,  Richard London ,  Duncan Maitland ,  Victor Esch

    发明人： Steven Visuri ,  Luiz Da Silva ,  Peter Celliers ,  Richard London ,  Duncan Maitland ,  Victor Esch

    IPC分类号： A61B17/22 ,  A61B18/20 ,  A61B18/22 ,  A61B18/24 ,  A61N5/06 ,  A61B18/18

    CPC分类号： A61B18/245 ,  A61B2018/20359 ,  A61B2018/2211

    摘要： Partial or total occlusions of fluid passages within the human body are removed by positioning an array of optical fibers in the passage and directing treatment radiation pulses along the fibers, one at a time, to generate a shock wave and hydrodynamic flows that strike and emulsify the occlusions. A preferred application is the removal of blood clots (thrombi and emboli) from small cerebral vessels to reverse the effects of an ischemic stroke. The operating parameters and techniques are chosen to minimize the amount of heating of the fragile cerebral vessel walls occurring during this photoacoustic treatment. One such technique is the optical monitoring of the existence of hydrodynamic flow generating vapor bubbles when they are expected to occur and stopping the heat generating pulses propagated along an optical fiber that is not generating such bubbles.

    摘要翻译： 通过将光纤阵列定位在通道中并沿着纤维一次一个地引导处理辐射脉冲来去除人体内的流体通道的部分或完全闭塞，以产生冲击波和流体动力学流动，其冲击和乳化 闭塞。 优选的应用是从小脑血管移除血块（血栓和栓塞）以逆转缺血性卒中的作用。 选择操作参数和技术以最小化在该光声处理期间发生的脆弱的脑血管壁的加热量。 一种这样的技术是当期望发生流体动力学流动产生蒸汽气泡的存在并且阻止沿着不产生这种气泡的光纤传播的发热脉冲时的光学监测。

    System for diffusing light from an optical fiber or light guide
    7.
    发明申请
    System for diffusing light from an optical fiber or light guide 有权
    用于漫射光纤或光导的光的系统

    公开(公告)号：US20080019657A1

    公开(公告)日：2008-01-24

    申请号：US11489138

    申请日：2006-07-18

    申请人： Duncan Maitland ,  Ward Small ,  Thomas Wilson ,  William Benett

    发明人： Duncan Maitland ,  Ward Small ,  Thomas Wilson ,  William Benett

    IPC分类号： G02B6/00 ,  G02B6/26 ,  G02B6/42

    CPC分类号： G02B6/262 ,  G02B6/0008

    摘要： A system for diffusing light from an optical fiber wherein the optical fiber is coupled to a light source, comprising forming a polymer element adapted to be connected to the optical fiber and incorporating a scattering element with the polymer element wherein the scattering element diffuses the light from the polymer element. The apparatus of the present invention comprises a polymer element operatively connected to the optical fiber and a scattering element operatively connected with the shape polymer element that diffuses the light from the polymer element.

    摘要翻译： 一种用于从光纤漫射光的系统，其中所述光纤耦合到光源，包括形成适于连接到所述光纤的聚合物元件并且与所述聚合物元件结合散射元件，其中所述散射元件将来自 聚合物元素。 本发明的装置包括可操作地连接到光纤的聚合物元件和与聚合物元件的光扩散的形状聚合物元件可操作地连接的散射元件。